scholarly journals Impact of stroke history on the presence of cerebral microbleeds in hemodialysis patients

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Toshihide Naganuma ◽  
Daijiro Kabata ◽  
Yoshiaki Takemoto ◽  
Junji Uchida ◽  
Ayumi Shintani
Keyword(s):  
Multivariable Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Cerebral Microbleeds ◽  
Cross Sectional ◽  
Ischemic Cerebrovascular Disease ◽  
High Prevalence ◽  
History Of ◽  
Weighted Magnetic Resonance Imaging ◽  
Magnetic Resonance Imaging Mri

Abstract Introduction Cerebral microbleeds (CMBs) are detected on gradient-echo T2*-weighted magnetic resonance imaging (MRI). Clinically, CMBs are often detected after stroke, including in cases of intracerebral hemorrhage and ischemic cerebrovascular disease. Hemodialysis (HD) patients are widely known to have a high incidence of stroke, and HD patients without stroke history have been reported to have a high prevalence of CMBs. In this study, we investigated whether history of stroke affects the prevalence of CMBs in HD patients. Methods A cross-sectional study was performed in 241 HD patients who underwent brain T2*-weighted MRI. We compared the prevalence of CMBs between the patients with and without a history of stroke. Moreover, the relationship between history of stroke and presence of CMBs was examined by multivariate logistic regression analysis. Results Among these patients, 22 (9.1%) had a history of stroke. CMBs were detected in 70 patients (29.0%). The prevalence of CMBs was significantly higher in patients with a history of stroke compared to those without this history (54.5 vs. 26.5%, p = 0.012). In the multivariable analysis adjusted for background characteristics, history of stroke was a significant and independent factor related to CMBs (OR: 3.24, 95%CI: 1.18–8.89, p = 0.02). Discussion/conclusions As has been reported for non-dialysis patients, our results showed a high prevalence of CMBs in HD patients with a history of stroke, and indicated that a history of stroke is significantly and independently associated with CMBs in HD patients.

scholarly journals Prevalence of MDR organism (MDRO) carriage in children and their household members in Siem Reap Province, Cambodia

2020 ◽  
Vol 2 (4) ◽  
Author(s):  
Shweta R Singh ◽  
Bunsoth Mao ◽  
Konstantin Evdokimov ◽  
Pisey Tan ◽  
Phana Leab ◽  
...  
Keyword(s):  
Final Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Middle Income ◽  
E Coli ◽  
Middle Income Countries ◽  
Siem Reap ◽  
High Prevalence ◽  
Significant Public Health ◽  
History Of

Abstract Background The rising incidence of infections caused by MDR organisms (MDROs) poses a significant public health threat. However, little has been reported regarding community MDRO carriage in low- and middle-income countries. Methods We conducted a cross-sectional study in Siem Reap, Cambodia comparing hospital-associated households, in which an index child (age: 2–14 years) had been hospitalized for at least 48 h in the preceding 2–4 weeks, with matched community households on the same street, in which no other child had a recent history of hospitalization. Participants were interviewed using a survey questionnaire and tested for carriage of MRSA, ESBL-producing Enterobacterales (ESBL-E) and carbapenemase-producing Enterobacterales (CPE) by culture followed by antibiotic susceptibility testing. We used logistic regression analysis to analyse associations between collected variables and MDRO carriage. Results Forty-two pairs of households including 376 participants with 376 nasal swabs and 290 stool specimens were included in final analysis. MRSA was isolated from 26 specimens (6.9%). ESBL-producing Escherichia coli was detected in 269 specimens (92.8%) whereas ESBL-producing Klebsiella pneumoniae was isolated from 128 specimens (44.1%), of which 123 (42.4%) were co-colonized with ESBL-producing E. coli. Six (2.1%) specimens tested positive for CPE (4 E. coli and 2 K. pneumoniae). The prevalence ratios for MRSA, ESBL-producing E. coli and ESBL-producing K. pneumoniae carriage did not differ significantly in hospital-associated households and hospitalized children compared with their counterparts. Conclusions The high prevalence of ESBL-E across both household types suggests that MDRO reservoirs are common in the community. Ongoing genomic analyses will help to understand the epidemiology and course of MDRO spread.

scholarly journals Study of the health status of geriatric age group in Chitwan district of Nepal

2015 ◽  
Vol 5 (1) ◽  
pp. 11-17
Author(s):  
L Subedi ◽  
R B Sah
Keyword(s):  
Health Status ◽  
Well Being ◽  
Cross Sectional Study ◽  
Living Alone ◽  
Age Group ◽  
Cross Sectional ◽  
High Prevalence ◽  
Health Related ◽  
History Of ◽  
Mental Well Being

Retirement, change in housing, illness or death of spouse greatly affect the physical and mental well-being of the geriatric person. This study aims to find out the health status of geriatric age group in chitwan district of Nepal. A cross sectional study was carried out among 300 geriatric people where 15.7% of the geriatric were living alone, 50.3 % and 39.7% of geriatrics gave history of regular use of tobacco and alcohol respectively. Co-morbidities were found in 63% of geriatrics who suffered from 2 or more diseases. In Total 44% were found to have Ophthalmic problems, 23% were found to have ENT problems, 5.33% were found to mental disorders, 33% were found to have CVS problems, 43% were found to have GI problems, 15.67 % were found to have Metabolic disorder. The study highlighted a high prevalence of morbidity and health related problems in geriatric age groups.DOI: http://dx.doi.org/10.3126/jcmc.v5i1.12560

Prevalence and Determinants of Malnutrition Among Reproductive Aged Women of Rural Bangladesh

2009 ◽  
Vol 22 (1) ◽  
pp. 110-117 ◽  
Author(s):  
Abul Hasnat Milton ◽  
Wayne Smith ◽  
Bayzidur Rahman ◽  
Bashir Ahmed ◽  
S.M. Shahidullah ◽  
...  
Keyword(s):  
Rural Women ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Health Consequences ◽  
Cross Sectional ◽  
High Prevalence ◽  
Pregnancy Status ◽  
History Of ◽  
Reproductive Aged Women ◽  
Special Priority

Malnutrition among the rural Bangladeshi women of reproductive age is still very high. This high prevalence attributes to a range of adverse health consequences on the women and their offspring. A total of 2341 women aged between 20 and 45 years residing in the study area were interviewed in this cross-sectional study. Information on socioeconomic variables, nutritional status, and pregnancy-related history was obtained using interviewer administered questionnaire. A total of 34% of the reproductive aged rural women suffer from malnutrition. A multivariate analysis shows association between malnutrition and monthly household income, history of taking oral contraceptive, current pregnancy status, and history of breastfeeding. The final regression model shows a statistically significant decreasing trend in malnutrition status with increasing income ( P for trend <.001). The economic and health consequences of malnutrition in this group of women are enormous. National nutritional program should target this women group for any intervention with a special priority.

Traumatismo dento-alveolar em escolares de uma ONG em Salvador-Bahia: uma abordagem epidemiológica

2019 ◽  
Vol 9 ◽  
pp. 173
Author(s):  
Tatiana Frederico de Almeida ◽  
Carolina Silva Cervino Garcia
Keyword(s):  
Young People ◽  
Cross Sectional Study ◽  
Older Children ◽  
Cross Sectional ◽  
Children And Young People ◽  
Oral Health Problem ◽  
The Family ◽  
High Prevalence ◽  
History Of ◽  
Dentoalveolar Trauma

Introdução: O traumatismo dento-alveolar em vários locais do mundo tem alta prevalência na dentição decídua e permanente de crianças e jovens, com cerca de um terço destes sendo afetados. Objetivo: descrever a prevalência e gravidade de traumatismo dento-alveolar em crianças e jovens de 03 a 18 anos, assim como fatores associados. Metodologia: Foi realizado estudo transversal no Centro de Integração Familiar em Salvador, Bahia, que atende cerca de 400 crianças e jovens. Foram registradas informações sociodemográficas e história do trauma. O estudo foi realizado com uma amostra de 357 escolares. Resultados: A amostra tinha idade média de 8,3 anos. A prevalência do traumatismo foi de 15,69%, sendo a fratura de esmalte o agravo mais frequentemente encontrado, e sua etiologia principal a queda. Conclusão: O trauma acometeu o sexo feminino, as crianças mais velhas, de cor branca/outras, com overjet acentuado e com mais de dois irmãos. É necessária maior divulgação de informações de prevenção deste problema de saúde bucal.AbstractIntroduction: Dento-alveolar trauma in many places around the world has a high prevalence in deciduous and permanent dentition of children and young people, with about one third of them being affected. Objective: To describe the prevalence and severity of dentoalveolar trauma in children and young people from 03 to 18 years old, as well as associated factors. Methodology: A cross-sectional study was conducted at the Family Integration Center in Salvador, Bahia, which serves about 400 children and young people. Sociodemographic information and history of trauma were recorded. The study was conducted with a sample of 357 students. Results: The sample had a mean age of 8.3 years. The prevalence of trauma was 15.69%, with the enamel fracture being the most frequently encountered injury, and its main etiology being the fall. Conclusion: The trauma affected females, older children, white/others people, with severe overjet and with more than two siblings. More information on prevention of this oral health problem is needed.

Syphilis and HIV Infection among Displaced Pregnant Women in Rural Mozambique

1994 ◽  
Vol 5 (2) ◽  
pp. 117-123 ◽  
Author(s):  
H A Cossa ◽  
S Gloyd ◽  
R G Vaz ◽  
E Folgosa ◽  
E Simbine ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Pregnant Women ◽  
Hiv Transmission ◽  
Perinatal Transmission ◽  
Anal Intercourse ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Hiv Seroprevalence ◽  
High Prevalence ◽  
History Of

A cross-sectional study was conducted among displaced pregnant women in Mozambique to determine the prevalence and correlates of HIV infection and syphilis. Between September 1992 and February 1993, 1728 consecutive antenatal attendees of 14 rural clinics in Zambézia were interviewed, examined, and tested for HIV and syphilis antibodies. The seroprevalence of syphilis and HIV were 12.2% and 2.9%, respectively. Reported sexual abuse was frequent (8.4%) but sex for money was uncommon. A positive MHA-TP result was significantly associated with unmarried status, history of past STD, HIV infection, and current genital ulcers, vaginal discharge, or genital warts. Significant correlates of HIV seropositivity included anal intercourse, history of past STD, and syphilis. In summary, displaced pregnant women had a high prevalence of syphilis but a relatively low HIV seroprevalence suggesting recent introduction of HIV infection in this area or slow spread of the epidemic. A syphilils screening and treatment programme is warranted to prevent perinatal transmission and to reduce the incidence of chancres as a cofactor for HIV transmission.

scholarly journals High Prevalence of Infertility among Women with Graves’ Disease and Hashimoto’s Thyroiditis

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Alessandra Quintino-Moro ◽  
Denise E. Zantut-Wittmann ◽  
Marcos Tambascia ◽  
Helymar da Costa Machado ◽  
Arlete Fernandes
Keyword(s):  
Autoimmune Diseases ◽  
Hashimoto’S Thyroiditis ◽  
Cross Sectional Study ◽  
Hashimoto's Thyroiditis ◽  
Graves Disease ◽  
Cross Sectional ◽  
Unprotected Sexual Intercourse ◽  
High Prevalence ◽  
History Of ◽  
Endocrinology Clinic

Objectives. To evaluate the prevalence of infertility in women with Graves’ disease (GD) or Hashimoto’s thyroiditis (HT) and associated factors.Material and Methods. This cross-sectional study was conducted at the Endocrinology Clinic for Thyroid Autoimmune Diseases, with 193 women aged 18–50 years with GD and 66 women aged 18–60 years with HT. The women were interviewed to obtain data on their gynecological and obstetric history and family history of autoimmune diseases. Their medical records were reviewed to determine the characteristics of the disease and to confirm association with other autoimmune diseases. Infertility was defined as 12 months of unprotected sexual intercourse without conception.Results. The prevalence of infertility was 52.3% in GD and 47.0% in HT. Mean age at diagnosis was 36.5 years and 39.2 years, in GD and HT, respectively. The mean number of pregnancies was lower in women who were 35 years old or younger at diagnosis and was always lower following diagnosis of the disease, irrespective of age. The only variable associated with infertility was a shorter time of the disease in HT.Conclusions. The prevalence of infertility was high in women with GD and HT and affected the number of pregnancies in young women.

scholarly journals Pathogenic NOTCH3 Variants Are Frequent Among the Korean General Population

2021 ◽  
Vol 7 (6) ◽  
pp. e639
Author(s):  
Chul-Hoo Kang ◽  
Young Mee Kim ◽  
Yang-Ji Kim ◽  
Su-Jeong Hong ◽  
Do Yoon Kim ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Genome Project ◽  
Jeju Island ◽  
Cross Sectional ◽  
Genome Database ◽  
Pathogenic Variants ◽  
Number Of Patients ◽  
High Prevalence ◽  
History Of ◽  
Reference Genome Database

ObjectiveThis study aimed to determine the frequency of pathogenic NOTCH3 variants among Koreans.MethodsIn this cross-sectional study, we queried for pathogenic NOTCH3 variants in 2 Korean public genome databases: the Korean Reference Genome Database (KRGDB) and the Korean Genome Project (Korea1K). In addition, we screened the 3 most common pathogenic NOTCH3 variants (p.Arg75Pro, p.Arg544Cys, and p.Arg578Cys) for 1,000 individuals on Jeju Island, where the largest number of patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) have been reported in Korea.ResultsThe pathogenic NOTCH3 variant (p.Arg544Cys) was found in 0.12% of sequences in the KRGDB, and 3 pathogenic variants (p.Arg75Pro, p.Arg182Cys, and p.Arg544Cys) were present in 0.44% of the Korea1K database. Of the 1,000 individuals on Jeju Island, we found 2 cysteine-altering NOTCH3 variants (p.Arg544Cys variant in 9 and p.Arg578Cys in 1 individual) in 1.00% of the participants (95% confidence interval: 0.48%–1.83%). The presence of cysteine-altering NOTCH3 variants was significantly associated with a history of stroke (p < 0.001).DiscussionPathogenic NOTCH3 variants are frequently found in the general Korean population. Such a high prevalence of pathogenic variants could threaten the brain health of tens of thousands to hundreds of thousands of older adults in Korea.

scholarly journals Incidence and Risk Factors of Post-Operative Delirium in Elderly Patients Who Underwent Spinal Anesthesia in Orotta, Halibet and Sembel Hospitals: A Cross Sectional Study in Eritrea

2021 ◽  
pp. 1-8
Author(s):  
Michael Beraki Mengistu ◽  
◽  
Yonatan Mehari Andemeske ◽  
AriamTsegay Emhatsion ◽  
HabtomTareke Wrieta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Spinal Anesthesia ◽  
Significant Risk ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of

Background: Delirium is a common but often underdiagnosed set of transient symptoms often seen in elderly patients following surgeries under spinal anesthesia. With early recognition and diagnosis based on the established standard criteria delirium can be improved. Early identification of the possible contributingfactors and the magnitude of the burden will help in the management of the fragile elderly patients. The aim of this study is to determine the incidence of postoperative delirium and associated risk factors in elderly patients who have done surgery under spinal anesthesia. Method: This cross sectional study was conducted in the National Referral Hospitals and Sembel PrivateHospital, in Asmara, Eritrea from February to May, 2019. The study participants were elderly patients (age ≥65 years) having no known history of dementia or delirium or no mental disorder, no history of acute cerebrovascular disease. Basic background and clinical characteristics of the patients was collected. To assess the status of cognitive impairment level, the Mini Mental State Examination and Confusion Assessment Method tools were used. Data was collected through an interview method. After the data was entered into SPSS version 22 software, data was analyzed with frequency, percentage, bivariate and multivariate logistic regression analysis method as appropriate. P value <0.05 was considered as statistically significant. Results: The mean age of the participants was 74 ±6.62 and 102 (79.1%) of the participants were males. POD occurred in 14 (10.9%) of the patients. Adjusting all the potential factors, age was identified as arisk factor for developing POD. Conclusion: Age was determined to be a significant risk factor of delirium. Elderly patients require more attention and care and the findings might help to develop preventive strategies to the occurrence of POD

scholarly journals The Prevalence of Allergic Rhinitis, Eczema and Asthma in Students of Guidance Schools in Mazandaran Province, Iran

2016 ◽  
Vol 4 (4) ◽  
pp. 619-623 ◽  
Author(s):  
Daniel Zamanfar ◽  
Javad Ghaffari ◽  
Salar Behzadnia ◽  
Jamshid Yazdani-charati ◽  
Sahar Tavakoli
Keyword(s):  
Allergic Rhinitis ◽  
Cross Sectional Study ◽  
Caesarian Section ◽  
Sectional Study ◽  
Mazandaran Province ◽  
Cross Sectional ◽  
High Prevalence ◽  
History Of ◽  
Spss Software ◽  
Allergic Disorders

BACKGROUND: Eczema, allergic rhinitis and asthma are common chronic allergic disorders in childhood.AIM: The aim of this study was to determine the prevalence of common allergic disorders among Iranian guidance schools students in Mazandaran Province, northern Iran.METHODS: This analytical cross-sectional study was performed on 3000 children aged 11‐14 years old during 2012‐13 according to ISAAC study. Of 3000 recruited children 1576 (52.54%) were female and 1424 (47.46%) were male. Data gathered by ISAAC first phase questionnaire analysed by SPSS software 20.RESULTS: The prevalence of wheezing, allergic rhinitis symptoms (sneezing and pruritus) and atopic dermatitis symptoms (pruritus skin lesion) were 30.5%, 30% and 15% respectively. History of pets contact and smoking was positive 6.6% and 36 % respectively. About 52% was born with caesarian section. There was wheezing in 32.5% during sport. The diagnosis of asthma, allergic rhinitis and eczema were 12.2%, 28.5% and 15% respectively. Eczema, asthma and allergic rhinitis were significantly more common in boys students (p < 0.05).CONCLUSIONS: The results of this study showed that asthma, allergic rhinitis and eczema have a high prevalence and they are more common in boys.

scholarly journals Are presbyopes willing to pay for spectacles? A Cross-sectional study’’

2019 ◽  
Author(s):  
Haile Woretaw Alemu ◽  
Anthony Carlson
Keyword(s):  
Willingness To Pay ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Monthly Income ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
History Of ◽  
The Mean ◽  
South Gondar

Abstract Objective Cross-sectional study design were used to assess willingness to pay for spectacles among south Gondar presbyopic population.Results Of the total 322 people participating in the study, only 53.4% (172) were experienced by spectacles users. The median gross monthly income of participants was US$ 75.0 (ranged US$ 7.1 - 321.4) and the mean amount of money willing to pay for a pair of spectacles was US$ 17.9 (ranged US$ 1.1-107.1). Participants who were willing to pay US$ 12.5 for a pair of spectacles from a government optical accounted for 63.0% (95% CI: 57.8-68.3), while those willing to pay the minimum international pair of spectacle price US$ 5.6 were accounted 73.9% (95% CI: 68.9-79.2%) and spectacle from local private optical price US$ 17.8 accounted 46.6% (95% CI: 40.4-52.2). Multivariate logistic regression analysis indicated factors such as age (P=0.049), occupation (0.001), monthly income (0.001) and history of the previous spectacle wear (0.005) to be significantly associated with willingness to pay for a pair of spectacles. Public willingness to pay for a pair of spectacle has to be supported with the accessible provision of spectacles to increase spectacle coverage among presbyopic individuals.

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