scholarly journals Alcohol consumption in relation to cardiovascular and non-cardiovascular mortality in an elderly male Chinese population

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiao-Fei Ye ◽  
Chao-Ying Miao ◽  
Wei Zhang ◽  
Chang-Sheng Sheng ◽  
Qi-Fang Huang ◽  
...  

Abstract Background We investigated the association of alcohol consumption with cardiovascular and non-cardiovascular mortality in elderly Chinese men. Methods Our participants were recruited from residents living in a suburban town of Shanghai (≥60 years of age, n = 1702). Alcohol intake was classified as non-drinkers, past drinkers (stopped drinking for ≥12 months), and current light-to-moderate (1 to 299 g/week) and heavy drinkers (≥300 g/week). Alcoholic beverages were classified as beer/wine, rice aperitif and liquor/mix drinking. Results During 5.9 years (median) of follow-up, all-cause, cardiovascular and non-cardiovascular deaths occurred in 211, 98 and 113 participants, respectively. The corresponding incidence rates were 23.6/1000, 10.9/1000 and 12.6/1000 person-years, respectively. Both before and after adjustment for confounding factors, compared with non-drinkers (n = 843), past drinkers (n = 241), but not the current light-to-moderate (n = 241) or heavy drinkers (n = 377), had a higher risk of all-cause (adjusted hazard ratio [HR] 1.90, 95% confidence interval [CI] 1.35–2.68, P = 0.0003) and non-cardiovascular mortality (HR 2.46, 95% CI 1.55–3.91, P = 0.0001). Similar trends were observed for cardiovascular mortality (HR 1.44, 95% CI 0.85–2.44, P = 0.18). In similar unadjusted and adjusted analyses, compared with the current beer/wine drinkers (n = 203), liquor/mix drinkers (n = 142), but not aperitif drinkers (n = 273), had a significantly higher risk of all-cause (HR 3.07, 95% CI 1.39–6.79, P = 0.006), and cardiovascular mortality (HR 10.49, 95% CI 2.00–55.22, P = 0.006). Similar trends were observed for non-cardiovascular mortality (HR 1.94, 95% CI 0.73–5.16, P = 0.18). Conclusions Our study showed risks of mortality associated with past drinking and liquor drinking in the elderly Chinese men.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lizhen Han ◽  
Jinzhu Jia

Abstract Background In the context of increasing global aging, the long-term effects of alcohol consumption on cognitive function in older adults were analyzed in order to provide rationalized health recommendations to the elderly population. Methods The study used the Chinese Longitudinal Healthy Longevity Survey (CLHLS) dataset, from which 5354 Chinese seniors aged 65–112 years were selected as the subjects, spanning the years 1998–2018. Data on alcohol, diet, activity, and cognition were collected by questionnaire and cognitive levels were judged by the Mini-Mental State Examination scale (also referenced to the Functional Assessment Staging Test). Data cleaning and preprocessing was implemented by R software. The dynamic Cox model was applied for model construction and data analysis. Results The results of the dynamic Cox model suggested that seniors who drank alcohol were at higher risk of cognitive decline compared to those who never drank (HR = 1.291, 95%CI: 1.175–1.419). The risk was similarly exacerbated by perennial drinking habits (i.e., longer drinking years, HR = 1.008, 95%CI: 1.004–1.013). Compared to non-alcoholic beverages, liquor (≥ 38°), liquor (< 38°), wine and rice wine all showed negative effects. Whereas, the risk of cognitive decline was relatively lower in seniors who consumed liquors (< 38°) and rice wine compared to the high-level liquor (HR: 0.672 (0.508, 0.887) and 0.732 (0.559, 0.957), respectively). Conclusions Alcohol consumption has a negative and long-term effects on cognitive function in seniors. For the elderly, we suggested that alcohol intake should be avoided as much as possible.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Siwen Zhang ◽  
Yujia Liu ◽  
Gang Wang ◽  
Xianchao Xiao ◽  
Xiaokun Gang ◽  
...  

Aim. The relationship between alcohol consumption and glycometabolic abnormality is controversial, especially in different ethnic population. In this study, a cross-sectional survey was carried out to examine the relationship between alcohol consumption and glycometabolic abnormality in middle-aged and elderly Chinese men. Methods. Using cluster random sampling, Chinese men aged more than 40 years from Changchun, China, were given standardized questionnaires. In total, 1996 individuals, for whom complete data was available, were recruited into the study. We calculated the incidence of prediabetes and newly diagnosed diabetes by three levels of alcohol consumption: light, moderate, and heavy. Multivariate logistic regression models adjusted for socioeconomic variables and diabetes-related risk factors were used to analyze the association between alcohol consumption and the onset of prediabetes and diabetes. Results. The univariate analysis revealed higher incidence of prediabetes among drinkers (32.8%) compared with nondrinkers (28.6%), particularly in heavy alcohol consumers. The logistic regression analysis showed that alcohol consumption, especially heavy consumption, was an independent risk factor for prediabetes. Conclusions. Alcohol consumption, heavy consumption in particular, is an independent risk factor for the development of prediabetes, but not for diabetes.


PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e77919 ◽  
Author(s):  
Liang Shi ◽  
Xiao-Ou Shu ◽  
Honglan Li ◽  
Hui Cai ◽  
Qiaolan Liu ◽  
...  

Author(s):  
Karina Conde ◽  
Paula Victoria Gimenez ◽  
Tomás Salomón ◽  
Raquel Inés Peltzer ◽  
Sebastián Laspiur ◽  
...  

The impact of the COVID-19 pandemic and isolation measures on alcohol consumption remains unknown among Latin-American countries. This paper characterizes differences in alcohol consumption and related problems before and after the pandemic among Argentinians from different genders, age groups, income levels, and behaviors regarding the acquisition of alcoholic beverages. Through an online survey 1446 participants were assessed regarding four alcohol consumption dimensions (frequency, quantity, heavy episodic drinking -HED- and alcohol-related problems) three months prior and after the first cases in the country and subsequent lockdown measures. Overall, participants reported small reductions for usual consumption and moderate ones for HED and related problems. As expected, very high reductions were found for those underage (14 to 18 years), and young adults (19 to 24 years). Those who had an increase in income after the pandemic did not report changes in consumption, while those whose income remained equal or lowered reported reductions. Those who did not report special behaviors to acquire alcohol (e.g. pre-stocking) informed decreases in consumption compared to those who did. This study provides new evidence on the impact of environmental factors in public health, suggesting restricted access to alcohol generates a significant decrease in alcohol consumption and related problems.


2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Lei Duan ◽  
Yongyi Bai ◽  
Man Li ◽  
Huiying Li ◽  
Yanping Li ◽  
...  

Abstract Background It is well established that long-term use of aspirin can cause gastric mucosal injury. ACEIs and ARBs are inversely related to gastric ulcer development. This study aimed to evaluate the relationship between SLCO1B1 polymorphisms, which can affect ACEI and ARB transport, and gastric mucosal erosion in elderly male Chinese patients with cardiovascular disease who use aspirin. Methods Patients taking aspirin and an ACEI or ARB concomitantly who had undergone endoscopic screening for gastric erosion were analyzed for SLCO1B1 polymorphisms by a TaqMan assay. Results The frequency of the SLCO1B1*1b/*1b diplotype (42% vs. 24%; p = 0.002) was significantly higher in the gastric mucosal erosion group than in the control group. After adjustment for significant factors, SLCO1B1*1b/*1b (OR, 2.64; 95% CI, 1.59–4.17; p < 0.05) was found to be associated with gastric mucosal erosion in aspirin users. Conclusions The presence of the SLCO1B1*1b/*1b diplotype may be a risk factor for aspirin-induced gastric mucosal erosion in elderly Chinese men taking aspirin and an ACEI or ARB concomitantly.


2012 ◽  
Vol 8 (4) ◽  
pp. 202
Author(s):  
Nancy Swanida Henriette Malonda ◽  
Lucia Kris Dinarti ◽  
Retno Pangastuti

Background: Hypertension is one of the major chronic diseases in the elderly and the prevalence is constantly increasing. The results of Health Research Survey (Riskesdas) in 2007 showed that the prevalence of hypertension in the city of Tomohon was 41.6%. The prevalence of fatty foods consumption in Tomohon was relatively high, amounted to 17.2%. The proportion of alcohol consumer in North Sulawesi province was higher (17.4%) than the National proportion (4.6%), and Tomohon has signifi cantly higher alcohol consumers (36%). The consumption pattern of fatty foods and alcoholic beverages were factors that might increase the risk of hypertension.Objectives: To identify the infl uence of eating pattern and alcohol consumption as risk factors of hypertension in the elderly at Tomohon Municipality.Methods: This is an analytic observational study with case control design. Subjects were elderly people aged 60 – 65 years at Tomohon Municipality consisted of 76 cases (hypertensive) and 76 control (non-hypertensive). Data was collected through structured interviews, food frequency questionaire (FFQ ) was used to assess dietary pattern, mental health questionnaire (Self Reporting Questionnaire) was used to determine the condition of stress, waist-hip ratio measurement for obesity status, and blood pressure measurements. Data were analysed by bivariate and multiple logistic regression analysis.Results: The result of bivariate analysis showed that fat intake (OR=3.046; 95% CI:1.338 –6.933; p=0.008), alcohol consumption (OR=2.8; 95% CI:1.418 – 5.299; p=0.003), and obesity (OR=2.4; 95% CI:1.072 – 5.404; p=0.033) signifi cant increase the risk of hypertension. The intake of natrium, potassium and calcium, family history, smoking and stress showed no signifi cant association with hypertension. Statistical analysis revealed that the variables that become dominant risk factors for hypertension and affected the incidence of hypertension were fat (OR=3.303; 95% CI:1.346 – 8.10; p=0.009) and alcohol consumption (OR=2.792; 95% CI:1.347–5.789; p=0.006).Conclusion: High fat and alcohol consumption were risk factors that affect the incidence of hypertension amongst the elderly at Tomohon Municipality.


2020 ◽  
Author(s):  
Lizanne JS Schweren ◽  
Jan Haavik ◽  
Lin Li ◽  
Berit Skretting Solberg ◽  
Henrik Larsson ◽  
...  

AbstractExcessive alcohol intake compromises cognitive functioning. At the same time, moderate alcohol consumption is reported to protect against Alzheimer’s disease among elderly. Little is known about dose-dependent effects of alcohol consumption on higher-order cognitive functioning among generally healthy adults. Here, we applied propensity weighted analyses to investigate associations between habitual drinking patterns and executive functioning in the general population.A community sample of N=78,832 Dutch adults (age 18-65, 40.9% male) completed the Ruff Figural Fluency Task of executive functioning (range 1-165), and self-reported their past month consumption of alcoholic beverages on a food frequency questionnaire. Participants were stratified according to drinking level (abstinent [22.0%], occasional [<2.5 g/day, 21.4%], light [2.5–14.9 g/day, 42.9%], moderate [15–29.9 g/day, 11.4%], or heavy [>30 g/day, 2.3%]) and binge-drinking (yes [10.6%] vs. no [89.4%]). Groups were equivalised using multinomial propensity score weighing based on demographic, socioeconomic, health-related and psychosocial factors influencing drinking behaviour.Compared to abstinent participants, task performance was better among light drinkers (β[95% CI]=0.056[0.033-0.078] or +1.3 points, p<0.0001) and moderate drinkers (β[95% CI]=0.111[0.079-0.143] or +2.5 points, p<0.0001), but not among occasional drinkers (β[95% CI]=0.018[-0.006-0.043], p=0.1432) or heavy drinkers (β[95% CI]=0.075[-0.009-0.158], p=0.0791). No difference was found between binge-drinkers and non-binge-drinkers (β[95% CI]=0.032[-0.002-0.066], p=0.0654).In conclusion, we observed better executive functioning in light-moderate drinkers compared to abstainers, but not in occasional drinkers, heavy drinkers or binge-drinkers. This non-linear association is reminiscent of the dose-dependent effect of alcohol consumption on cardiovascular risk. Further studies may determine whether cardiovascular, inflammatory and/or other somatic factors mediate the association between moderate drinking and higher-order cognitive functions. Although analyses were adjusted for observed factors that influence drinking behaviours, we cannot exclude a contribution from unobserved residual confounding.


2001 ◽  
Vol 120 (5) ◽  
pp. A117-A117
Author(s):  
K DEAR ◽  
M BRADLEY ◽  
K MCCORMACK ◽  
R PECK ◽  
D GLEESON

Author(s):  
Niken Setyaningrum ◽  
Andri Setyorini ◽  
Fachruddin Tri Fitrianta

ABSTRACTBackground: Hypertension is one of the most common diseases, because this disease is suffered byboth men and women, as well as adults and young people. Treatment of hypertension does not onlyrely on medications from the doctor or regulate diet alone, but it is also important to make our bodyalways relaxed. Laughter can help to control blood pressure by reducing endocrine stress andcreating a relaxed condition to deal with relaxation.Objective: The general objective of the study was to determine the effect of laughter therapy ondecreasing elderly blood pressure in UPT Panti Wredha Budhi Dharma Yogyakarta.Methods: The design used in this study is a pre-experimental design study with one group pre-posttestresearch design where there is no control group (comparison). The population in this study wereelderly aged over> 60 years at 55 UPT Panti Wredha Budhi Dharma Yogyakarta. The method oftaking in this study uses total sampling. The sample in this study were 55 elderly. Data analysis wasused to determine the difference in blood pressure before and after laughing therapy with a ratio datascale that was using Pairs T-TestResult: There is an effect of laughing therapy on blood pressure in the elderly at UPT Panti WredhaBudhi Dharma Yogyakarta marked with a significant value of 0.000 (P <0.05)


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