scholarly journals Demographic, lifestyle, and reproductive determinants of serum anti-Müllerian hormone levels in adult women of reproductive age in Ilorin, North-Central Nigeria

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Oyinkansola Islamiyat Lawal ◽  
Jameelu-deen Omokunmi Yusuff
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Cycle Length ◽  
Univariate Analysis ◽  
Multivariable Analysis ◽  
Negative Relationship ◽  
Reproductive Age ◽  
Enzyme Linked Immunosorbent Assay ◽  
Adult Women ◽  
Women Of Reproductive Age

Abstract Background Anti-Müllerian hormone is a dimeric glycoprotein produced by the granulosa cells of preantral and small antral follicles of the ovaries. It is a reliable biomarker of ovarian reserve, ageing, and response in the management of women with infertility. However, there are few studies on the determinants of serum anti-Müllerian hormone in Nigerian women. This study aimed to investigate determinants of serum anti-Müllerian hormone among adult women of reproductive age. The study was a hospital-based cross-sectional study involving 161 women of reproductive age attending the gynaecology clinic and immunisation clinic of a Nigerian tertiary hospital. Baseline characteristics were collected using a semi-structured questionnaire. Serum anti-Müllerian hormone was quantified using enzyme-linked immunosorbent assay. Results In univariate analysis, age (B = − 0.035, P = 0.000), parity (B = − 0.080, P = 0.001), and infertility duration (B = − 0.050, P = 0.011) had a negative relationship with serum anti-Müllerian hormone, while ethnicity (B = 0.180, P = 0.040), body mass index (B = 0.015, P = 0.010), and cycle length (B = 0.042, P = 0.000) had a positive relationship with serum anti-Müllerian hormone. In multivariable analysis, all relationships except infertility duration persisted. Conclusion We found that age, ethnicity, parity, infertility duration, body mass index, and cycle length were associated with serum anti-Müllerian hormone. A large prospective population-based study is required to better understand factors that are associated with serum anti-Müllerian hormone in an ethnically diverse country like Nigeria.

scholarly journals Pattern of Body Mass Index and Common Health Problems in Women of Reproductive Age Group in a Private Clinic in Kathmandu

2017 ◽  
Vol 56 (207) ◽  
pp. 352-356 ◽  
Author(s):  
Saraswati M Padhye
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Health Problems ◽  
Overweight And Obesity ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Reproductive Age Group ◽  
Genitourinary Infection

Introduction: High Body Mass Index is one of the risk factors for many chronic diseases and adverse health outcomes. It is associated with an increased risk of coronary heart disease, ischemic stroke, high blood pressure and type 2 diabetes mellitus. It also have many adverse effect on reproductive health of the women like sub fertility, polycystic ovarian disease, menstrual abnormality etc. The purpose of this study is to find Basal Metabolic Rate and the diseases pattern of reproductive age woman in Nepal. Methods: This is a descriptive study of women of reproductive age (15 to 49 years) attending a private gynaecology clinic in Kathmandu Valley from October 2016 to June 2017. Six hundred and eight women of current reproductive age group participated in this study. Women’s particulars and complaints were noted down. Detailed history was taken. Height, weight and blood pressure were recorded and general examination was done. BMI was calculated as BMI is weight in kilogram divided by height in meter square, and it was interpreted as per WHO guidelines. Results: Out of the total 608 participants, 243 (40%) were overweight, 96 (15.8%) were obese. Regarding the common health problems, 154 (25.3%) have sub fertility and 199 (32%) had genitourinary infection. Similarly, 90 (14.8%) had menstrual problems. Conclusions: Prevalence of overweight and obesity has risen significantly comparing to the study done decade ago in same setting. Similarly, sub fertility rate has also risen whereas the prevalence of genitourinary infections has decreased. Keywords: BMI; genitourinary infection; Nepal-reproductive age women; sub fertility.

scholarly journals Normal uterine size in women of reproductive age in northern Islamic Republic of Iran

2004 ◽  
Vol 10 (3) ◽  
pp. 437-441
Author(s):  
S. Esmaelzadeh ◽  
N. Rezaei ◽  
M. Hajiahmadi
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Reproductive Age ◽  
Islamic Republic ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Nulliparous Women ◽  
Multiparous Women ◽  
Islamic Republic Of Iran ◽  
Ultrasonographic Assessment

Todetermine the efficacy of ultrasonographic assessment of uterus size in women of reproductive age, we conducted a cross-sectional analytic study of 231 women aged 15-45 years in Babol, northern Islamic Republic of Iran. Mean uterus size was 86.6 mm x 49.6 mm x 40.6 mm overall, 72.8 mm x 42.8 mm x 32.4 mm for nulliparous women and 90.8 mm x 51.7 mm x 43.0 mm for multiparous women. Mean age was 31.7 +/- 9.6 years and mean body mass index [BMI] was 24.7 +/- 4.0 kg/m2. Uterus size was significantly associated with parity and age; but not with BMI. Our findings show a greater mean uterus size than reported by others. Ultrasonographic measurement of uterus size is valuable for predicting pathologies associated with abnormal uterine size

Abstract 5714: Influence of Body Mass Index on Early Diastolic Untwisting Velocity in Healthy Children

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Christine O’Reilly ◽  
Katrina Abhayaratna ◽  
Satoru Sakuragi ◽  
Richard Telford ◽  
Walter P Abhayaratna
Keyword(s):  
Body Mass Index ◽  
Heart Rate ◽  
Body Mass ◽  
Univariate Analysis ◽  
Multivariable Analysis ◽  
Left Ventricular ◽  
Lv Function ◽  
Healthy Children ◽  
Diastolic Relaxation ◽  
And Function

Background: Childhood obesity is increasingly prevalent in the community and is predictive of adverse cardiovascular outcomes in adulthood. We hypothesised that increased body mass index (BMI) in children has an adverse influence on left ventricular (LV) untwisting, a sensitive marker of LV function that reflects a key process in the transition between LV relaxation and suction. Methods: Cardiac structure and function were assessed by transthoracic echocardiography. LV twist mechanics were quantitated using 2-dimensional speckle tracking imaging of the LV base and apex in short axis. Univariate associations of LV untwisting velocity (Er) were evaluated using Spearman’s correlation analysis. Significant univariate predictors (p≤0.10) were included into multivariable regression analysis to determine the independent relationship between body mass and Er (rad/s). Results: Of the first 150 children assessed (age 10.2 ± 0.3 years; 83 boys), the mean BMI was 18.2 ± 2.8 kg/m 2 . In univariate analysis, Er was inversely related to BMI (ρ= −0.13, p=0.10), LV end-diastolic diameter (ρ= −0.13, p=0.10) and LV end-systolic diameter (ρ= −0.28, p<0.001); and positively correlated with LV torsion (ρ=0.55, p<0.001), LV twisting velocity (ρ=0.29, p<0.001), early diastolic annular velocity (e′) (ρ=0.13, p=0.10), LV ejection fraction (EF) (ρ=0.14, p=0.09) and heart rate (ρ=0.18, p=0.03). There was no correlation between Er and LV relative wall thickness or mass index (p>0.25). In multivariable analysis, body mass index was independently associated with Er, independent of LV torsion, heart rate, EF, LV chamber size and e′ (Table ). Conclusion: Increased body mass is independently related to lower LV untwisting velocity during early diastole in healthy children. Additional studies are required to evaluate whether lifestyle measures to reduce body mass will attenuate further deterioration in LV diastolic relaxation and suction. Table: Independent Predictors of Left Ventricular Untwisting Velocity in Children

Features of metabolic and hormonal abnormalities in women with metabolic syndrome at the stage pregrada

2017 ◽  
pp. 57-61
Author(s):  
O.A. Dyndar ◽  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Reproductive System ◽  
The Body ◽  
Reproductive Age ◽  
High Density Lipoproteins ◽  
Women Of Reproductive Age ◽  
Female Population ◽  
Number Of Components

The problem of obesity and metabolic syndrome among the female population of Ukraine is extremely important, given the current trend toward increasing age of realization of reproductive function,. The prevalence of metabolic syndrome among women of reproductive age is 6–35%, fertility problems are found in 30-35% of women. The objective: to study the characteristics of metabolic disorders and hormonal condition of the reproductive system in women with obesity and the metabolic syndrome on pregravidarity stage depending on the body mass index and severity of metabolic syndrome. Patients and methods. We examined a total of 124 women with obesity and metabolic syndrome that appealed on pregravidar stage and 53 women who had no history of somatic and gynecological pathology. Antropometric studies, determination of blood pressure, examination of carbohydrate and lipid metabolism, evaluation of the endocrine status of the reproductive system, ultrasound examination of small pelvis organs were done. Results. In women of reproductive age, we observed increase of total cholesterol, triglycerides, low-density lipoproteins and decrease high-density lipoproteins, with a predominance of IIb and IV types of dyslipidemia. Insulin resistance was diagnosed in 28.3% of women And 47.4% – II and in 69.7% with III degree of obesity. Metabolic syndrome was diagnosed in 79.2% of patients with obesity of I, in 94.7% – II 100% III. The number of components of metabolic syndrome correlate directly proportional to the severity of obesity. The index of fertility with III degree of obesity increased to 2.7, hypoestrogenia marked with And hyperestrogenia from 50.7% of women in II and III degree of obesity, progesterona failure identified at 66.9%, hyperandrogenism in 58.8%, reduced sex-binding globulin in 83.0% of the observations. Conclusion. Pathological changes of the hormonal status of the female reproductive system on prepregnansy stage is directly proportional to depend on the body mass index number of components of metabolic syndrome and dysmetabolic disorders. Key words: obesity, metabolic syndrome, pregnancy planning.

scholarly journals KORELASI INDEKS MASA TUBUH DENGAN KADAR TRIGLISERIDA

2019 ◽  
Vol 3 (2) ◽  
pp. 52
Author(s):  
Marisa Ester Nurdamayanti ◽  
Yunus Elon
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Univariate Analysis ◽  
Age Groups ◽  
Sampling Technique ◽  
P Value ◽  
Adult Women ◽  
Cross Sectional ◽  
Pearson Product Moment Correlation ◽  
Purposive Sampling

One cause of risk factors for ischemic stroke is high triglycerides in the blood due to excessive fat intake. This study aims to determine the picture and the relationship between BMI (Body Mass Index) and blood triglyceride (TG) levels in adult women. The research method used was analytic survey with Cross Sectional approach. The sample used is adult women aged 26-45 years who live in Cihanjuang Rahayu Village by using purposive sampling technique. BMI is measured by comparing the results of height calculation with body weight. Triglycerides are taken after fasting for 10 hours and analyzed in a laboratory by Lab personnel. Univariate analysis result showed the majority of respondents had an excess BMI of 73.3%, normal triglyceride levels of 93.9%. The results of the correlation test analysis using Pearson Product-Moment Correlation 0.119 with p-value = >0.05. This show that there is no significant relationship between BMI and triglyceride levels. In the future studies it is necessary to compare between male and female sexes and different age groups in order to provide a complete picture if BMI with triglycerides. Keywords: BMI, Body Mass Index, Triglyceride, Obesity   Abstrak Salah satu penyebab faktor resiko terjadinya stroke iskemia yaitu tingginya trigliserida dalam darah akibat intake lemak yang berlebihan. Penelitian ini bertujuan untuk mengetahui gambaran dan hubungan antara indeks massa tubuh dan kadar trigliserida (TG) darah pada wanita dewasa. Metode penelitian yang digunakan adalah survei analitik dengan pendekatan Cross Sectional. Sampel yang digunakan yaitu wanita dewasa yang berusia 26-45 tahun yang tinggal di Desa Cihanjuang Rahayu dengan menggunakan teknik purposive sampling. Indeks massa tubuh diukur dengan membandingkan hasil perhitungan tinggi badan dengan berat badan. Trigliserida diambil setelah puasa selama 10 jam dan dianilisa dilaboratorium oleh petugas Lab. Hasil analisis univariate menunjukkan mayoritas responden memiliki indeks massa tubuh berlebih sebanyak 73,3%, kadar trigliserida normal sebanyak 93,9%. Hasil analisis Uji korelasi menggunakan Pearson Product-Moment Correlation 0.119 dengan p-value = >0.05. Hal ini menunjukkan tidak ada hubungan yang bermakna antara indeks massa tubuh dengan kadar trigliserida dalam darah. Pada penelitian selanjutnya perlu membandingkan antara jenis kelamin pria dan wanita serta kelompok usia berbeda agar dapat memberikan gambaran utuh tentang indeks massa tubuh dengan Trigliserida. Kata Kunci: Indeks Massa Tubuh, Trigliserida, Obesitas

Effect of body mass index on outcomes in biliary tract cancer.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 399-399
Author(s):  
Mark Doherty ◽  
Mairead Geraldine McNamara ◽  
Priya Aneja ◽  
Lisa W Le ◽  
Sean P. Cleary ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Prognostic Factors ◽  
Body Mass ◽  
Biliary Tract ◽  
Biliary Tract Cancer ◽  
Univariate Analysis ◽  
Multivariable Analysis ◽  
Prognostic Variables ◽  
Tract Cancer ◽  
Definitive Surgery

399 Background: Biliary Tract Cancer (BTC) is associated with poor outcomes, and prognostic factors are not well documented. Body Mass Index (BMI) has been shown to correlate with survival in colon, breast, lung and prostate cancer. The effect of BMI on survival in patients with BTC is unclear. Greater understanding of prognostic markers in BTC can help with treatment decisions. Methods: Patients treated for BTC in Princess Margaret Cancer Centre between 06/1987 and 08/2014 were included for analysis. Data were collected on clinicopathologic features, BMI, and survival. Patients were separated into two groups by resectability: definitive surgery (DS) or no definitive surgery (NDS). Multivariable proportional hazards regression was used to investigate the association between variables and overall survival (OS) for DS and NDS groups. Results: 902 patients (461 DS, 441 NDS) were included, with median BMI 25.7 (range 15.5-48.7). Median OS was 48.1 months in DS patients and 11 months in NDS patients. 244 NDS patients received palliative chemotherapy (55%). BMI was prognostic for OS in DS patients. In univariate analysis, DS patients with BMI <25 had poorer outcomes than those with BMI ≥25 [HR 1.40, 95% CI 1.08-1.82, p=0.01]. In multivariable analysis, the effect of BMI in DS patients remained significant: BMI <25 was associated with poorer OS [HR 1.36, 95%CI 1.03-1.81, p=0.03]. No significant differences were found in OS in NDS patients according to BMI by univariate [HR 1.04, 95%CI 0.83-1.29, p=0.74] or multivariable analysis. Prognostic factors by multivariable analysis are summarized in the Table. Conclusions: For patients undergoing definitive surgery for BTC, BMI <25 was a poor prognostic marker independent of other known prognostic variables. Other prognostic variables from our dataset match reported literature. This study is limited by its retrospective nature, however BMI may aid patient risk stratification after DS for BTC. [Table: see text]

ETIOPATHOGENETIC ASPECTS, CLINICAL AND DIAGNOSTIC CRITERIA AS WELL AS COMPREHENSIVE APPROACH TO TREATMENT OF METABOLIC SYNDROME IN WOMEN OF REPRODUCTIVE AGE

2020 ◽  
pp. 40-44
Author(s):  
O. V. Dolenko
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Transvaginal Ultrasound ◽  
Combined Treatment ◽  
Clinical Effectiveness ◽  
Comprehensive Approach ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Clinical Efficiency

The development of metabolic syndrome in women of reproductive age is one of the most common causes of anovulatory infertility, miscarriage in early pregnancy. In this pathology treatment in women there is used a comprehensive approach, which aims to restore specific functions, i.e. menstrual, secretory and reproductive ones. Important points are the detection of metabolic disorders in the patients before the formation of polycystic ovaries, normalization of body weight. In order to study the clinical effectiveness of the herbal drug "Glucemedin" in the combined treatment of metabolic syndrome in 40 women of reproductive age, a clinical and laboratory investigation was performed, also transvaginal ultrasound and body mass index were determined. In the first group of patients as the main treatment the metformin was prescribed hydrochloride as monotherapy in a dosage of 500 mg 2 times a day, in the second there was added phytodrug "Glucemedin" in a dosage of 1 capsule 3 times a day. The combined treatment showed a more pronounced dynamics of reduction of total and free cholesterol, low−density lipoprotein, triglycerides, atherogenic factor, decreased body mass index compared with the patients receiving metformin monotherapy. Based on analysis of the results of clinical and laboratory studies a high clinical efficiency of the herbal phytodrug "Glucemedin", which is stipulated with the pronounced effect on lipid spectrum of blood. The presence of natural components being a part of the phytodrug "Glucemedin", their high bioavailability, safety of the drug, no side effects and contraindications indicate its pronounced clinical effectiveness and feasibility of inclusion into the treatment of metabolic syndrome in women of childbearing age. Key words: metabolic syndrome, lipid profile, body mass index, transvaginal ultrasound, Glucemedin, clinical efficiency, combined treatment, women of reproductive age.

scholarly journals Daily Profiles of Dehydroepiandrosterone and Its Hydroxylated Metabolites with Respect to Food Intake

2015 ◽  
Vol 116 (1) ◽  
pp. 40-48 ◽  
Author(s):  
Luboslav Stárka ◽  
Beata Rácz ◽  
Monika Šrámková ◽  
Martin Hill ◽  
Michaela Dušková
Keyword(s):  
Body Mass Index ◽  
Food Intake ◽  
Steroid Hormones ◽  
Body Mass ◽  
Reproductive Age ◽  
Normal Body Mass Index ◽  
Women Of Reproductive Age ◽  
Hydroxylated Metabolites ◽  
Hormonal Milieu ◽  
Main Meals

Eight women of reproductive age with normal body mass index were given 5 standardised meals, and their hormonal milieu was determined during the course of the day. Plasma from 12 withdrawals was analysed for dehydroepiandrosterone and its 7- and 16-hydroxylated metabolites. Overall, there was a maximum in the levels of steroid hormones in the morning, followed by decreases throughout the day. There was also an additional significant decrease found for dehydroepiandrosterone and its 7α-hydroxyderivative in association with the consumption of main meals, but not for the 7β-isomer or 16α-hydroxyderivative.

scholarly journals Features of the hormonal profile in obese reproductive-age women

2020 ◽  
Vol 5 (3) ◽  
pp. 77-84
Author(s):  
N. V. Artymuk ◽  
O. A. Tachkova ◽  
N. A. Sukhova
Keyword(s):  
Insulin Resistance ◽  
Body Mass Index ◽  
Body Mass ◽  
Density Lipoprotein ◽  
Dehydroepiandrosterone Sulfate ◽  
Reproductive Age ◽  
Obese Women ◽  
Women Of Reproductive Age ◽  
Hormonal Profile ◽  
Reproductive Age Women

Aim. To assess the hormonal profile features in obese reproductive-age women. Materials and Methods. We consecutively enrolled 163 women of reproductive age (140 women with body mass index ≥ 30 kg/m2 and 23 women with normal body mass index) who have been admitted to Podgorbunskiy Regional Emergency Medicine Hospital. All patients of both groups underwent general and gynecological examination. Serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, estradiol, estrone, testosterone, dehydroepiandrosterone sulfate, thyroid-stimulating hormone, free triiodothyronine, total and free thyroxine, cortisol, leptin, immunoreactive insulin, and progesterone were assessed on days 5-6 and 21-22 of the menstrual cycle. Results. Obese women of reproductive age were characterised by higher values of LH, LH/ FSH ratio, testosterone, estradiol, estrone, leptin, IRI and by lower levels of FSH and progesterone compared with normal weight women. A direct correlation was found between the level of leptin and estrone (r = 0.21, p = 0.014), insulin resistance (r = 0.18, p = 0.039), triglycerides (r = 0.20, p = 0.030), and low-density lipoprotein cholesterol (r = 0.22, p = 0.016). There was a statistically significant inverse correlation between the level of leptin and high-density lipoprotein cholesterol (r = -0.18, p = 0.043). A direct correlation was established between insulin and LH (r = 0.24, p = 0.030), testosterone (r = 0.32, p = 0.037), dehydroepiandrosterone sulfate (r = 0.56, p = 0.003), insulin resistance (r = 0.95, p < 0.001), cholesterol (r = 0.20, p = 0.024), triglycerides (r = 0.29, p < 0.001). Conclusion. Obese women of reproductive age have certain hormonal features that underlie menstrual and reproductive disorders in these patients.

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