scholarly journals Oxidative stress and anti-oxidants in asymptomatic malaria-positive patients: a hospital-based cross-sectional Nigerian study

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Ayodele S. Babalola ◽  
J. Jonathan ◽  
Boluwatife E. Michael
Keyword(s):  
Oxidative Stress ◽  
Clinical Symptoms ◽  
Asymptomatic Malaria ◽  
Related Factors ◽  
Cross Sectional ◽  
Gray Area ◽  
Asymptomatic Patients ◽  
Strong Positive Relationship ◽  
The Mean ◽  
Elimination Goal

Abstract Background Asymptomatic malaria is a threat to malaria eradication program. Host-related factors (e.g., immunity, oxidative stress, anti-oxidants activities) associated with asymptomatic malaria remain a gray area in research. This study seeks to determine the serum level of oxidative stress and anti-oxidants in 130 symptomatic and asymptomatic patients with different intensities of malaria parasite infection from a hospital in Ibadan, Nigeria. Results The prevalence of infection was 48.5% among the respondents. Most of the patients with parasitemia were asymptomatic (64.7%). The mean titer value of malondialdehyde (MDA) was significantly higher (p < 0.05) among those with malaria infection (6.05 ± 0.60) compared with those who tested negative for malaria parasites (2.38 ± 0.28). Furthermore, the mean titer value of MDA was significantly higher (p < 0.05) among patients who showed symptoms of malaria (5.49 ± 0.77) compared with those without symptoms (2.93 ± 0.47). A strong positive relationship existed between MDA (r = 0.717, p < 0.05), glutathione peroxidase (GPx) (r = 0.695, p < 0.05), and density of infection. On the other hand, a weak negative correlation existed between intensity and superoxide dismutase (SOD) (r = − 0.115, p > 0.05) and glutathione (GSH) (r = − 0.278, p > 0.05). The level of SOD and GSH also decreased significantly (p < 0.05) with an increase in MDA level. Conclusions This study showed that lipid peroxidation did not only increase in positive patients, it also rises in patients with clinical symptoms of malaria. Furthermore, a similar level of anti-oxidant responses was observed in both symptomatic and asymptomatic malaria patients. There is a need to inform health policies that encourage routine diagnosis and treatment of malaria in apparently healthy people if the malaria elimination goal is to be achieved in Africa.

scholarly journals Investigation of work ability index (WAI) and its relationship with maximal aerobic capacity (VO2max) among cement industry employer

2020 ◽  
Author(s):  
M Kavousian ◽  
A Salehi sashlabadi ◽  
MJ Jafari ◽  
S Khodakarim ◽  
H Rabiei
Keyword(s):  
Sleep Quality ◽  
Aerobic Capacity ◽  
Work Experience ◽  
Cement Industry ◽  
Maximal Aerobic Capacity ◽  
Work Ability Index ◽  
Sports Activity ◽  
Related Factors ◽  
Cross Sectional ◽  
The Mean

Introduction: Given the importance of adapting workers' physical and mental capabilities to their job needs, measuring their ability to work, maintaining, and upgrading, it has become an essential task. This study aimed to investigate WAI and its relationship with VO2max at one of the cement companies. Materials and Methods: This cross-sectional study was conducted among 130 employees of a cement company in Iran in 2018. For data collection, the WAI, Queens's test for maximum oxygen consumption, and a questionnaire designed by researchers (socio-demographic and work-related factors) were used. SPSS 21 was used to analyze the data.  Results: The results showed that the mean ± standard deviation of WAI in staff was 39.35 ± 4.64. Among the demographic and related variables, sports activity (P > 0.04) and sleep quality (P < 0.001), and work experience (P> 0.046) were significantly correlated with WAI. There was a significant positive correlation between the mean score of WAI and Vo2max (r = 0.21, p < 0.05). Regression modeling showed that Vo2max was the only significant predictor of WAI. Conclusion: According to the results of the study, to control and enhance the ability of the staff of the study, occupational intervention programs should focus on improving sleep quality and increased exercise. Also, considering the positive relationship of Vo2max to the WAI of the surveyed staff, it is recommended to select suitable employees in terms of aerobic capacity according to the workload of the job.

scholarly journals Clinical features of imported cases of coronavirus disease 2019 in Tibetan patients in the Plateau area

2020 ◽  
Author(s):  
Yu Lei ◽  
Xiaobo Huang ◽  
Bamu SiLang ◽  
YunPing Lan ◽  
Jianli Lu ◽  
...  
Keyword(s):  
Clinical Laboratory ◽  
Clinical Symptoms ◽  
Asymptomatic Group ◽  
Asymptomatic Patients ◽  
Abnormal Chest ◽  
Plateau Area ◽  
Imported Cases ◽  
High Altitude Area ◽  
History Of ◽  
The Mean

AbstractCoronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, has rapidly spread throughout China, but the clinical characteristics of Tibetan patients living in the Qinghai-Tibetan plateau are unknown. We aimed to investigate the epidemiological, clinical, laboratory and radiological characteristics of these patients. We included 67 Tibetan patients with confirmed SARS-CoV-2 infection. The patients were divided into two groups based on the presence of clinical symptoms at admission, with 31 and 36 patients in the symptomatic and asymptomatic groups, respectively. The epidemiological, clinical, laboratory and radiological characteristics were extracted and analysed. No patient had a history of exposure to COVID-19 patients from Wuhan or had travelled to Wuhan. The mean age of Tibetan patients was 39.3 years and 59% of the patients were male. Seven patients presented with fever on admission and lymphocytopenia was present in 20 patients. 47 patients had abnormal chest CTs at admission instead of stating that 20 were unchanged. Lactate dehydrogenase levels were increased in 31 patients. Seven patients progressed to severe COVID-19; however, after treatment, their condition was stable. No patients died. Of the 36 asymptomatic patients, the mean age was younger than the symptomatic group (34.4±17.3vs 44.9±18.1 years, P=0.02). Lymphocyte count and prealbumin levels were higher in the asymptomatic group than the group with clinical symptoms (1.6±0.5 vs 1.3±0.6 and 241.8±68.2 vs 191.9±60.3, respectively; P<0.05). Imported cases of COVID-19 in Tibetan patients were generally mild in this high-altitude area. Absence of fever or radiologic abnormalities on initial presentation were common.

scholarly journals Emotion dysregulation in idiopathic rapid eye movement sleep behavior disorder

SLEEP ◽  
2019 ◽  
Author(s):  
Jin-Sun Jun ◽  
Ryul Kim ◽  
Hye-Min Jung ◽  
Jung-Ick Byun ◽  
Jin Myoung Seok ◽  
...  
Keyword(s):  
Emotion Regulation ◽  
Clinical Symptoms ◽  
Rem Sleep Behavior Disorder ◽  
Behavior Disorder ◽  
Control Group ◽  
Cognitive Emotion Regulation ◽  
Related Factors ◽  
Cross Sectional ◽  
Sleep Behavior ◽  
Korean Version

Abstract Study Objectives To characterize emotion regulation strategies in patients with idiopathic REM sleep behavior disorder (iRBD) and to explore whether these strategies are associated with clinical symptoms. Methods In this cross-sectional multicenter study, a total of 94 polysomnography-confirmed iRBD patients (mean age, 67.6 years; men, 56%) and 50 healthy controls (mean age, 65.4 years; men, 48%) completed the Cognitive Emotion Regulation Questionnaire (CERQ), the Korean version of the RBD questionnaire-Hong Kong (RBDQ-KR), the Buss-Durkee Hostility Inventory (BDHI), the second edition of the Beck Depression Inventory (BDI-II), and the Korean version of the Montreal Cognitive Assessment (MoCA-K). Results The iRBD group had lower CERQ adaptive scores than the control group, whereas the CERQ maladaptive scores were not significantly different between the groups. Among the CERQ adaptive subscales, the scores for positive refocusing, refocusing on planning, and positive reappraisal were significantly lower in the iRBD group than in the control group. Higher CERQ adaptive scores were correlated with lower scores on RBDQ-KR factor 1 (dream-related) and the BDI-II and higher MoCA-K scores but were not correlated with RBDQ-KR factor 2 (behavioral manifestation) or BDHI scores. Among the dream content-related items of RBDQ-KR factor 1, the CERQ adaptive score was associated only with frequent nightmares. No correlation was found between CERQ maladaptive scores and any variable except for a positive correlation with BDI-II scores. Conclusions Our results provide evidence of emotion regulation deficits in iRBD patients. Furthermore, these results were linked to dream-related factors, especially nightmares, along with depressive symptoms and cognitive impairment.

Effect of job and individual factors on Work Ability Index (WAI) in a dairy company

2016 ◽  
pp. 34-39
Author(s):  
Haji Omid Kalte
Keyword(s):  
Sleep Quality ◽  
Work Ability ◽  
Job Insecurity ◽  
Statistical Analyses ◽  
Work Ability Index ◽  
Related Factors ◽  
Cross Sectional ◽  
Work Related ◽  
Ability Index ◽  
The Mean

Abstract Background: The work ability index (WAI) is one the most widely used instruments for measuring perceived work ability. However, very few studies have used this instrument in Iran. The present study is designed to assess effect of individual and work-related risk factors on the WAI in one dairy factory. Methods: This cross-sectional study was designed among 117 workers. Work ability was measured by the Persian versions of Work Ability Index (P-WAI). An author-developed measure was used to assess individual and work-related factors. All Statistical analyses were performed using IBM SPSS Statistics 21 (USA, SPSS Inc.). Results: The mean age of participants was 32.38 ± 7.3 and the Mean score of the WAI was 44.92 ± 5.56. According to the categorical classification of WAI score, 10.9, 35.6, and 53.5 % of participants had moderate, good and excellent work ability, respectively. The results of statistical analyses showed that mean WAI significantly differed with age (0.049), sleep quality (p= 0.035) and employment status (p= 0.014). Conclusion: To improve the workers’ work ability, intervention programs should focus on improving sleep quality and exercise. Also, we suggest that increasing job insecurity should be considered an important intervention in promoting worker’s work ability. Keywords: Work Ability Index (WAI), Sleep Quality, Job Insecurity

scholarly journals Soft Tissue Sarcoma of Lower Extremity: Functional Outcome and Quality of Life

2021 ◽  
Author(s):  
Gilber Kask ◽  
Jussi P. Repo ◽  
Erkki J. Tukiainen ◽  
Carl Blomqvist ◽  
Ian Barner-Rasmussen
Keyword(s):  
Quality Of Life ◽  
Soft Tissue ◽  
Lower Extremity ◽  
Functional Outcome ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Related Factors ◽  
Cross Sectional ◽  
The Mean

Abstract Background Few studies have focused on patient-related factors in analyzing long-term functional outcome and health-related quality of life (HRQoL) in patients with postoperative lower extremity soft tissue sarcoma (STS). Objective The purpose of this study was to investigate factors associated with postoperative functional outcome and HRQoL in patients with lower extremity STS. Methods This cross-sectional study was performed in a tertiary referral center using the Toronto Extremity Salvage Score (TESS), Quality-of-Life Questionnaire (QLQ)-C30 and 15 Dimension (15D) measures. Functional outcome and HRQoL data were collected prospectively. All patients were treated by a multidisciplinary team according to a written treatment protocol. Results A total of 141 patients who had undergone limb-salvage surgery were included. Depending on the outcome measure used, 19–51% of patients were completely asymptomatic and 13–14% of patients had an unimpaired HRQoL. The mean score for TESS, 15D mobility score, and QLQ-C30 Physical Functioning scale were 86, 0.83, and 75, respectively, while the mean score for 15D was 0.88, and 73 for QLQ-C30 QoL. Lower functional outcome was statistically significantly associated with higher age, higher body mass index (BMI), and the need for reconstructive surgery and radiotherapy, while lower HRQoL was statistically significantly associated with higher age, higher BMI, and reconstructive surgery. Conclusion Functional outcome and HRQoL were generally high in this cross-sectional study of patients with STS in the lower extremity. Both tumor- and treatment-related factors had an impact but patient-related factors such as age and BMI were the major determinants of both functional outcome and HRQoL.

scholarly journals Investigation of Health-Promoting Lifestyle and its Determinants Among Students of Medical Sciences in Iran

2020 ◽  
Vol 13 (1) ◽  
pp. 627-633
Author(s):  
Mohammad Amiri ◽  
Ahmad Khosravi ◽  
Niloofar Aboozarzadeh ◽  
Leila Khojasteh ◽  
Zakieh Sadeghi ◽  
...  
Keyword(s):  
Self Efficacy ◽  
Pearson Correlation ◽  
Well Being ◽  
Cross Sectional Study ◽  
Medical Sciences ◽  
Related Factors ◽  
Cross Sectional ◽  
Health Promoting ◽  
The Mean ◽  
Health Promoting Lifestyle

Background: A person's lifestyle plays an important role in his health. This study aimed at determining thehealth-promoting lifestyle and its related factors among the medical students of Shahroud Islamic Azad University. Methods: In this cross-sectional study, a total of500 students of medical sciences were selected using the stratified random sampling method and they completed the health-promoting lifestyle, self-efficacy, and well-being questionnaires. The collected data were entered into SPSS 16 and were analyzed with a T-test, Chi-square, Pearson correlation coefficient, and a backward regression model. Results: The mean age of the students was 22.25±1.45 and 65% of the participants were female. The mean scores of health-promoting lifestyle, well-being, and self-efficacy were 134.1±23.85, 14.41±5.09, and 41.67±8.05, respectively. Among the students, 32.8% had a health disorder and only 2.2% had a high self-efficacy. Well-being and self-efficacy were statistically correlated with the health-promoting lifestyle (p<0.001). The results showed that out of 17 independent variables, only 4 variables of educational level, academic year, marital status, well-being were the best predictors of health-promoting lifestyle. Conclusion: More than 90% of students had low self-efficacy and more than 30% of them did not have good well-being. Moreover, the health-promoting lifestyle of students was moderate. More attention to the above areas, such as well-being status and applying required interventions, can help to improve the situation.

scholarly journals Evaluation of Oxidative Stress in Patients with Fracture Admitted to Khatam Al-Anbia Hospital in Zahedan

2020 ◽  
Vol 18 (3) ◽  
Author(s):  
Mansour Karajibani ◽  
Farzaneh Montazerifar ◽  
Faezeh Kazemi ◽  
Ali Reza Dashipour
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activities ◽  
Control Group ◽  
Case Group ◽  
Cross Sectional ◽  
Stress Markers ◽  
Significant Difference ◽  
Before And After ◽  
Markers Of Oxidative Stress ◽  
The Mean

Background: Caused by an imbalance in the body’s oxidant and antioxidant status, oxidative stress can give rise to tissue damage and exacerbation of many diseases. Objectives: This study investigated the oxidative stress markers in patients with fractures and healthy subjects. Methods: In a cross-sectional case-control study, 40 patients with fractures admitted to an orthopedic ward and 40 healthy, non-fractured patients were selected using convenience sampling. Serum was analyzed for oxidant and antioxidant activities based on standard methods. P < 0.05 was considered statistically significant. Results: There was a significant difference in mean TAC between the case (748.2 ± 302.83 μmol/L) and control (984.90 ± 207.02 μmol/L) groups (P = 0.003). The mean MDA was 16.61 ± 4.16 µmol/L in the case group and 18.45 ± 5.43 µmol/L in the control group (P = 0.09). The mean SOD was 63.41 ± 16.67 U/g Hb in the case group and 58.54 ± 21.83 U/g Hb in the control group (P = 0.2). There was no significant difference between the two groups in terms of BMI and other variables. Conclusions: A significant difference existed in TAC between the two groups, which indicated increased oxidative stress in patients. However, oxidative stress could occur before and after undergoing fractures. The results suggested a slight, but not significant, difference between the two groups in the SOD and MDA scores. More conclusive results are required to determine the enzymatic and non-enzymatic markers of oxidative stress in larger sample sizes and during different stages of treatment.

scholarly journals Correlation Between Anger, Sleep Quality, and Indoor Activities During COVID-19 Quarantine

2022 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Arash Mani ◽  
Mehdi Pasalar ◽  
Mahsa Kamali ◽  
Hossein Molavi Vardanjani ◽  
AliReza Estedlal ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Social Factors ◽  
Cross Sectional Study ◽  
Social Consequences ◽  
Related Factors ◽  
Cross Sectional ◽  
Persian Medicine ◽  
Life Threatening ◽  
The Mean ◽  
The Relationship

Background: Coronavirus disease 2019 (COVID-19) is a life-threatening disease that has spread globally and received international concern. Iran is one of the countries severely affected by this pandemic, implementing social lockdown and restrictive strategies. According to Persian medicine, restrictions like quarantine have psychological and social consequences. Objectives: This study aimed to investigate the relationship between sleep quality and anger behaviors in Iran and compare it with Persian medicine viewpoints. Methods: In this cross-sectional study, 739 participants were interviewed in April 2020 in Shiraz, Iran. The questionnaire included the Pittsburgh Sleep Quality Index (PSQI), the Multidimensional Anger Inventory (MAI), and items on demographics, temperament, and the quarantine situation social factors. All participants completed the questionnaires willingly and were ensured of data confidentiality. Results: We found that 58.3% of the participants had low sleep quality. Females showed higher scores on anger and its related aspects (P < 0.05). In addition, people with lower education and income levels revealed higher anger scores (P < 0.05). Moreover, the mean scores of anger and its related factors were higher in participants with low sleep quality, higher sleep latency, daytime dysfunction, and experience of using sleep medications (P < 0.05). Also, after adjustment for demographics and other social factors, the mean scores of anger and all of its aspects were higher in those with a sleep disorder, use of sleep medications, and daytime dysfunction (P < 0.05). Conclusions: In conclusion, our findings illustrated that various factors, including low sleep quality, are associated with anger in individuals with the experience of home quarantine during the COVID-19 outbreak. The outcome is compatible with Persian medicine evidence.

scholarly journals The Relation of Allergic Rhinitis Classification with IL-5 on The Aller-gic Rhinitis

2019 ◽  
Vol 2 (3) ◽  
pp. 123-127
Author(s):  
Ismayani
Keyword(s):  
Quality Of Life ◽  
Clinical Symptoms ◽  
Mean Value ◽  
P Value ◽  
Significant Relation ◽  
Cross Sectional ◽  
The Mean ◽  
The Impact

IL-5 is an important role cytokine on the RA. IL-5 has an important role on eosinophils. ARIA-WHO made classification of RA based on how long the clinical symptoms and the impact on quality of life. The aim of this study was to know the classification of RA with IL-5 on RA study. This study used a cross-sectional method with 39 samples. The examination of IL-5 used ELISA. The highest classification of RA was medium-severe persistent of 43.58% with the mean value IL-5 was 56.25 pg/ml. Based on the test of Kruskal Wallis, it was obtained p-value = 0.664. Conclusion: There was no significant relation between classification RA and IL-5.  

scholarly journals Prevalence and Correlates of Mycoplasma genitalium Infections among Patients Attending a Sexually Transmitted Infection Clinic in Guangdong, China a Cross-sectional Study

2020 ◽  
Author(s):  
Xiaohui Zhang ◽  
PZ Zhao ◽  
WJ Ke ◽  
LY Wang ◽  
Lai Sze Tso ◽  
...  
Keyword(s):  
Sexually Transmitted Infection ◽  
Clinical Symptoms ◽  
Mycoplasma Genitalium ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Asymptomatic Patients ◽  
Tract Infections

Abstract Background: Mycoplasma genitalium (MG) causes urogenital tract infections and is associated with reproductive morbidity. Although MG has been reported across many regions and population groups, it is not yet routinely tested for in China. Our study contributes to current research by reporting the prevalence and correlates of MG infection in patients attending a sexually transmitted infection (STI) clinic in Guangdong from Jan 2017-May 2018.Methods: Urethral (from 489 men) and endo-cervical (from 189 women) samples, blood samples, and patient histories (via questionnaires) were collected. Doctors clinically diagnosed anogenital warts (GW) during the examination (n=678). The presence of MG was evaluated using an in-house via polymerase chain reaction protocol. We also tested all participants for herpes simplex virus-2 (HSV-2), Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), syphilis and HIV. Univariate and multivariate logistic regression were used to evaluate factors associated with MG.Results: MG was detected in 7.2% (49/678) of the patients (men, 7.4%; women, 6.9%). The MG positivity rate was 14.2% among symptomatic patients, and 5.6% for asymptomatic patients , respectively. Only 36.7% (18/49) Mg positive patients were symptomatic. Among the MG-infected patients, 10.2% were co-infected with CT, 6.1% with NG, 8.2% with HSV-2, 4.1% with syphilis and 22.4% with GW. Presentation with clinical symptoms was significantly associated with MG infection [OR=2.52 (2.03-3.13)]. In our analysis, MG was not associated with other STIs.Conclusions: MG is a relatively common infection among individuals attending an STI clinic in Guangdong Province. Routine testing of symptomatic patients may be necessary, and more epidemiological studies are needed to provide evidence for future testing guidelines,

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