Use of a large bore syringe creates significantly fewer high intensity transient signals (HITS) into a cardiopulmonary bypass system than a small bore syringe

Perfusion ◽  
2006 ◽  
Vol 21 (1) ◽  
pp. 67-71 ◽  
Author(s):  
James L Rudolph ◽  
Daniel Tilahun ◽  
Patrick R Treanor ◽  
Val E Pochay ◽  
Meetali A Mahendrakar ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
High Intensity ◽  
Injection Rate ◽  
The Other ◽  
Arterial Line ◽  
Injection Time ◽  
Transient Signals ◽  
Relationship Of ◽  
The Relationship

Introduction: High intensity transient signals (HITS) have been reported to occur following perfusionist intervention during cardiac surgery. This study investigates the relationship of the syringe bore, injection rate, and HITS created. Methods: Syringes (10 mL) with a male luer-lock connection (Large Bore) and Abboject ‘jet syringes’ with a 20 GA needle and male luer-lock connector (Small Bore) were filled with 10 mL of 0.9 N saline. A perfusionist was randomly assigned a set of four similar syringes followed by the other syringe bore. Each of the four syringes was injected into an in vitro saline-primed cardiopulmonary bypass (CPB) system over 5, 10, 15, or 20 sec. Sixteen randomizations of small and large bore syringes were completed at the four injection times (128 injections). HITS in the CPB arterial line were detected with transcranial Doppler (TCD) probes, were recorded for the 2 min following the injection, and were counted independently off-line by two reviewers. Results: The use of a large bore syringe compared to a small bore syringe created significantly fewer HITS (29±6 versus 145±17 [mean±SEM], p <0.001) introduced into the CPB arterial line. Injection over a longer time produced significantly fewer HITS than shorter injection times ( p <0.001). Conclusion: Significantly fewer HITS are introduced into the CPB system by using standard syringes and slower injection time.

scholarly journals IMMUNE RESPONSES IN VITRO

1972 ◽  
Vol 136 (5) ◽  
pp. 1241-1257 ◽  
Author(s):  
Robert E. Click ◽  
Loretta Benck ◽  
Barbara J. Alter ◽  
Judith C. Lovchik
Keyword(s):  
Immune Responses ◽  
The Other ◽  
Dilution Technique ◽  
Antibody Synthesis ◽  
Different Strains ◽  
Relationship Of ◽  
The Relationship ◽  
Limiting Dilution

The finding that the relationship of the in vitro and in vivo responses of different strains of mice is under genetic control indicates that at least two mechanisms must operate under in vivo conditions to control 19S antibody synthesis. One is involved in the termination of 19S antibody synthesis; the other has a regulatory role on the magnitude of the response. In light of these findings, various concepts based on other genetically controlled immune responses and on the limiting dilution technique should be reassessed. Furthermore, the suppressive in vivo mechanism may be an important type of control in the resistance or susceptibility to the establishment or maintainance of neoplasms.

An in vitro comparison of the ability of three commonly used pediatric cardiopulmonary bypass circuits to filter gaseous microemboli

Perfusion ◽  
2010 ◽  
Vol 25 (4) ◽  
pp. 255-263 ◽  
Author(s):  
Richard W Melchior ◽  
Tami Rosenthal ◽  
Andrew C Glatz
Keyword(s):  
Cardiopulmonary Bypass ◽  
In Vitro Model ◽  
The Other ◽  
Arterial Line ◽  
Independent Variables ◽  
Absolute Flow ◽  
In Vitro Investigation ◽  
Vitro Model ◽  
Different Levels

Background: The purpose of this study was to compare the ability of three commonly used pediatric cardiopulmonary bypass (CPB) circuits to filter gaseous microemboli (GME) in an in vitro model. Methods: Devices were tested at different levels of two specific independent variables: volume of air injected (1, 3, 5ml) and percentage of each oxygenator’s rated flow (50%, 75%, 100%, 125%). The air-handling ability of each CPB circuit was determined by the Emboli Detection and Classification Quantifier (Luna Innovations Inc., Roanoke,VA). Results: At all tested conditions, the FX-05 allowed a higher percentage of GME when compared to either one or both of the other two CPB circuits. When comparing oxygenators at similar absolute flow rates, the KIDS D100/D130 CPB circuit performed worse compared to the other two CPB circuits. C onclusions: The combination of the Baby RX-05 oxygenator and Capiox AF02 arterial line filter provides the highest level of protection from air emboli in an in vitro investigation.

The Relationship of Width, Thickness, Volume and Load to Extension for Human Skin in Vitro

1980 ◽  
Vol 9 (4) ◽  
pp. 179-183 ◽  
Author(s):  
H L Stark ◽  
A Al-Haboubi
Keyword(s):  
Human Skin ◽  
Collagen Fibre ◽  
Phase Volume ◽  
Lateral Contraction ◽  
Low Stiffness ◽  
Phase Thickness ◽  
Relationship Of ◽  
The Relationship ◽  
Fibre Matrix

The relationships of width, thickness, volume and load to extension for human skin in vitro are reported. The specimens tested exhibited a low stiffness phase followed by a high stiffness phase. Volume rose than fell back to the initial volume at approximately the end of the low stiffness phase, and continued on falling to a final reduction of about 20 per cent at failure. Width decreased throughout, showing a maximum rate of reduction at approximately the end of the low stiffness phase. Thickness increased at a rate which also was maximum at the end of the low stiffness phase. The specimens used were long compared with their width and thickness thus offering no constraint to lateral contraction. An interpretation of this data in respect of the behaviour of the collagen fibre matrix is postulated.

scholarly journals On Newcomb's method of investigating periodicities and its application to Brückner's weather cycle

1914 ◽  
Vol 90 (619) ◽  
pp. 349-355
Keyword(s):  
Thermal Radiation ◽  
The Other ◽  
New Method ◽  
Critical Examination ◽  
Numerical Work ◽  
Average Value ◽  
Other Hand ◽  
Relationship Of ◽  
The Relationship ◽  
Great Simplicity

During the last few years of his life Prof. Simon Newcomb was keenly interested in the problem of periodicities, and devised a new method for their investigation. This method is explained, and to some extent applied, in a paper entitled "A Search for Fluctuations in the Sun's Thermal Radiation through their Influence on Terrestrial Temperature." The importance of the question justifies a critical examination of the relationship of the older methods to that of Newcomb, and though I do not agree with his contention that his process gives us more than can be obtained from Fourier's analysis, it has the advantage of great simplicity in its numerical work, and should prove useful in a certain, though I am afraid, very limited field. Let f ( t ) represent a function of a variable which we may take to be the time, and let the average value of the function be zero. Newcomb examines the sum of the series f ( t 1 ) f ( t 1 + τ) + f ( t 2 ) f ( t 2 + τ) + f ( t 3 ) f ( t 3 + τ) + ..., where t 1 , t 2 , etc., are definite values of the variable which are taken to lie at equal distances from each other. If the function be periodic so as to repeat itself after an interval τ, the products are all squares and each term is positive. If, on the other hand, the periodic time be 2τ, each product will be negative and the sum itself therefore negative. It is easy to see that if τ be varied continuously the sum of the series passes through maxima and minima, and the maxima will indicated the periodic time, or any of its multiples.

Investigation on Polymer Adsorption and Retention in a Polymer Flooded Reservoir

2013 ◽  
Vol 734-737 ◽  
pp. 1200-1203
Author(s):  
Shu Qiang Liu ◽  
Ji Cheng Zhang ◽  
Jin Cheng Xu
Keyword(s):  
Polymer Solution ◽  
Influencing Factors ◽  
Polymer Adsorption ◽  
Solution Concentration ◽  
Injection Rate ◽  
The Other ◽  
Injection Time ◽  
Factors Affecting ◽  
Dynamic Factors ◽  
Polymer Retention

During polymer flooding, certain amount of polymer would be lost. Polymer retention causes sweep volume expanding on one side, it also causes polymer loss on the other. Therefore, it is a very important topic to study the influencing factors of polymer retention. There are many factors affecting polymer retention process. This paper mainly studied the influence from dynamic factors such as polymer solution concentration, injection rate, injection time, injected pv number. This paper investigated the influence of these factors on polymer retention process, and optimized these factors to minimize polymer loss in reservoir.

scholarly journals Physical Activity and Psychological Well-Being: Testing Alternative Sociological Interpretations

1990 ◽  
Vol 7 (4) ◽  
pp. 329-346 ◽  
Author(s):  
William McTeer ◽  
James E. Curtis
Keyword(s):  
Physical Activity ◽  
Socioeconomic Status ◽  
Social Interaction ◽  
Physical Fitness ◽  
Well Being ◽  
The Other ◽  
Positive Zero ◽  
Psychological Well Being ◽  
Relationship Of ◽  
The Relationship

This study examines the relationship between physical activity in sport and feelings of well-being, testing alternative interpretations of the relationship between these two variables. It was expected that there would be positive relationships between physical activity on the one hand and physical fitness, feelings of well-being, social interaction in the sport and exercise environment, and socioeconomic status on the other hand. It was also expected that physical fitness, social interaction, and socioeconomic status would be positively related to psychological well-being. Further, it was expected that any positive zero-order relationship of physical activity and well-being would be at least in part a result of the conjoint effects of the other variables. The analyses were conducted separately for the male and female subsamples of a large survey study of Canadian adults. The results, after controls, show a modest positive relationship of physical activity and well-being for males but no such relationship for females. The predicted independent effects of the control factors obtained for both males and females. Interpretations of the results are discussed.

THE RELATIONSHIP OF THE SODIUM, POTASSIUM, AND CHLORIDE CONCENTRATION OF THE FEEDING TO THE WEIGHT GAIN OF PREMATURE INFANTS

PEDIATRICS ◽  
1962 ◽  
Vol 30 (6) ◽  
pp. 909-916
Author(s):  
Herbert I. Goldman ◽  
Samuel Karelitz ◽  
Hedda Acs ◽  
Eli Seifter
Keyword(s):  
Weight Gain ◽  
Sodium Chloride ◽  
Human Milk ◽  
Premature Infants ◽  
Chloride Concentration ◽  
The Other ◽  
Milk Formula ◽  
Sodium Potassium ◽  
Relationship Of ◽  
The Relationship

One hundred four healthy premature infants, of birth weight 1,000 to 1,800 gm, were fed one of five feedings: (1) human milk; (2) human milk plus 13 meq/l of sodium chloride; (3) human milk plus 13 meq/l of sodium chloride and 18 meq/l of potassium chloride; (4) a half-skimmed cows milk formula; and (5) a partially-skimmed vegetable oil, cows milk formula. The infants fed any of the three human milk formulas gained weight at a slower rate than the infants fed either of the two cows milk formulas. Infants whose diets were changed from unmodified human milk to the half-skimmed cows milk gained large amounts of weight, and at times were visibly edematous. Infants whose diets were changed from the human milks with added sodium chloride, to the half-skimmed cows milk, gained lesser amounts of weight and did not become edematous. The infants fed the two cows milk diets gained similar amounts of weight, although one diet provided 6.5 gm/kg/day, the other 3.1 gm/kg/day of protein.

Een beetje onsterfelijk

Lampas ◽  
2019 ◽  
Vol 52 (4) ◽  
pp. 437-452
Author(s):  
Gerard Boter
Keyword(s):  
Present Article ◽  
The Other ◽  
Relationship Of ◽  
The Relationship ◽  
Immortality Of The Soul

Summary The present article discusses three hotly debated interpretational issues in Diotima´s speech in Plato´s Symposium. The first of these is the relationship of Diotima´s speech to other dialogues, such as the Phaedo and the Republic, with regard to the immortality of the soul. It is argued that there is no discrepancy at all, because the immortality of the soul does not play any role in the Symposium. The second issue is the nature of the three classes of posterity: biological, spiritual and philosophical. Whereas the posterity of the first two classes can be relatively easily defined, the character of the philosopher´s posterity, ‘true virtue’, remains rather vague. It may consist in dialectical teaching of the Idea of Beauty by Socrates. Thirdly, it is argued that the philosopher´s immortality differs only gradually from the immortality of the other two classes, that is, the philosopher as a man only survives by means of his posterity.

Comparing the Arrangements of Governance and Sustainable Development in OECD Countries: Coupled or Decoupled?

2019 ◽  
Vol 34 (1) ◽  
pp. 99-117
Author(s):  
Huh Taewook
Keyword(s):  
Sustainable Development ◽  
Oecd Countries ◽  
The Other ◽  
Type Analysis ◽  
Ideal Types ◽  
Type 3 ◽  
Relationship Of ◽  
The Relationship

This study attempts to analyze to what extent governance and sustainable development (SD) empirically appear compatible in the thirtyfive OECD countries through the fuzzy-set ideal type analysis, and identify which ideal types appear coupled or decoupled, and then reveal which countries belong to the coupled types or to the decoupled types. In short, twenty-two countries (including Sweden (fuzzy score, 0.953), Denmark (0.920), Finland (0.914), Norway (0.911) in Type 1 (G*S, ‘strong G-S coupled countries’); and Turkey (0.906), Greece (0.833), Mexico (0.828) in Type 4 (g*s, ‘lite g-s coupled countries’) are in line with the accepted conventions regarding the compatible relationship between governance and SD. On the other hand, the rest of thirteen countries (including USA (fuzzy score, 0.815), Luxembourg (0.721), Australia (0.660) in Type 2 (G*s, ‘G-s decoupled countries’); and Slovenia (0.728), France (0.644), Czech Rep. (0.625) in Type 3 (g*S, ‘g-S decoupled countries’) may indicate that the relationship of governance and SD is in fact experiencing tensions in the national contexts. These findings are characterized by the substance (of SD) and procedure (of governance) divide. Considering the results, this study focuses on the idea of reflexivity or reflexive capacity.

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