scholarly journals A Longitudinal Study of Growth, Sex Steroids, and IGF-1 in Boys With Physiological Gynecomastia

2015 ◽  
Vol 100 (10) ◽  
pp. 3752-3759 ◽  
Author(s):  
Mikkel G. Mieritz ◽  
Lars L. Rakêt ◽  
Casper P. Hagen ◽  
John E. Nielsen ◽  
Maj-Lis M. Talman ◽  
...  
Keyword(s):  
Pubertal Development ◽  
Free Testosterone ◽  
Serum Levels ◽  
Median Number ◽  
Peak Height ◽  
Height Velocity ◽  
Peak Height Velocity ◽  
Serum Hormone ◽  
Longitudinal Part ◽  
Igf Binding

Context: Physiological gynecomastia is common and affects a large proportion of otherwise healthy adolescent boys. It is thought to be caused by an imbalance between estrogen and testosterone, although this is rarely evident in analyses of serum. Objective: This study aimed to describe the frequency of physiological gynecomastia and to determine possible etiological factors (eg, auxology and serum hormone levels) in a longitudinal setup. Design, Settings, and Participants: A prospective cohort study of 106 healthy Danish boys (5.8–16.4 years) participated in the longitudinal part of the COPENHAGEN Puberty Study. The boys were examined every 6 months during an 8-year follow-up. Median number of examinations was 10 (2–15). Main outcome measurements: Blood samples were analyzed for FSH, LH, testosterone, estradiol, SHBG, inhibin B, anti-Müllerian hormone, IGF-1, and IGF binding protein-3 by immunoassays. Auxological parameters, pubertal development, and the presence of gynecomastia were evaluated at each visit. Results: Fifty-two of 106 boys (49%) developed gynecomastia, of which 10 (19%) presented with intermittent gynecomastia. Boys with physiological gynecomastia reached peak height velocity at a significantly younger age than boys who did not develop gynecomastia (13.5 versus 13.9 years, P = .027), and they had significantly higher serum levels of IGF-1 (P = .000), estradiol (P = .013), free testosterone (P < .001), and FSH (P = .030) during pubertal transition. However, no differences in serum LH or in the estradiol to testosterone ratio were found. Conclusions: Gynecomastia is frequent in pubertal boys. Increased IGF-1 levels and pubertal growth appear to be associated, whereas changes in estrogen to testosterone ratio seem negligible.

IMPACT OF INFECTIOUS DISEASES ON PUBERTAL TIMING IN UKRAINIAN GIRLS: RESULTS A MULTICENTER STUDY

2021 ◽  
Vol 74 (10) ◽  
pp. 2392-2399
Author(s):  
Aidyn G. Salmanov ◽  
Orusia A. Kovalyshyn ◽  
Roman S. Scoreiko ◽  
Victor M. Zinchenko ◽  
Serhiy M. Baksheev ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Bacterial Infections ◽  
Viral Infections ◽  
Age Of Onset ◽  
Final Height ◽  
Pubertal Development ◽  
Age At Onset ◽  
Peak Height ◽  
Height Velocity ◽  
Peak Height Velocity

The aim: To determine current age at the initiation of puberty for Ukrainian school-aged girls and infections impact to puberty. Materias and methods: We performed a multicentre cohort study. The analyses are based on data that were collected and evaluated biannually on Ukrainian school girls aged 6-17 years from 5 regions of Ukraine. Pubertal development was classified according to the Marshall and Tanner criteria. Results: Overall, 2,784 girls have been included in the study. Mean age of onset of puberty in Ukrainian girls was 10.1±1.0 yrs. Age of onset of pubic hair was 11.0±1.0 yrs and that of axillary hair was 11.6±1.0 yrs. Mean age in girls of menarche was 12.2±0.9 yrs. There were no significant correlations between age at onset of puberty and body mass index, final height, total peak height velocity, duration of puberty, and peak height velocity. A total of 2,420 infectious diseases were diagnosted. Of these, 64.8% were viral and 35.2% bacterial infections, respectively. Ukrainian girls with infectious diseases (especially viral infections) had older age at pubertal onset and positive association of infections in childhood with late age of menarche. Conclusions: Infectious morbidity (especially viral infections) in girls may be associated with later puberty. The lowering of the number of infections in childhood could be an additional factor that contributes to earlier puberty. To reduce infectious diseases, more attention should be paid to the vaccination of children.

scholarly journals Biological maturation of Portuguese rhythmic gymnasts in different competition levels of performance

2019 ◽  
Vol 8 (1) ◽  
pp. 38-48
Author(s):  
Amanda Batista ◽  
Rui Garganta ◽  
Lurdes Ávila-Carvalho
Keyword(s):  
Pearson Correlation ◽  
Pubertal Development ◽  
Peak Height ◽  
Height Velocity ◽  
Chronological Age ◽  
Training Volume ◽  
Competitive Performance ◽  
Peak Height Velocity ◽  
Biological Maturation ◽  
Competition Level

The aims of the present study were: (1) identify and compare the biological maturity in Portuguese gymnasts across competitive levels; (2) investigate how morphological variables and training volume behave in the different status and indicators of maturity and (3) determinate if the maturity status influences the competitive performance. The sample (n=164) consisted of three competition levels (Base, 1st division and Elite) from Portugal. Anthropometric measurements and body composition were performed. For analysis of biological maturation, the sexual and somatic maturation were evaluated. For the statistical analysis, Mann-Whitney and Kruskal-Wallis tests, Pearson correlation and Linear Regression were used. In total, 63.4% of gymnasts had not yet reached menarche and the higher competition level, lower the number of gymnasts with menarche. On mean, all groups had reached the age at peak height velocity. The higher the competition level, higher the chronological age and age at peak height velocity. Thus, the maturation indicators showed a delay in pubertal development in all competition levels and the elite gymnasts seem present a later pubertal development. The chronological age, the values of body mass, height, BMI and body fat increased with the maturity status according all maturity indicators. However, gymnasts with different maturity status revealed similar training volume. Finally, the maturational status explained 11.5% of competition success with higher advantage in the competitive performance to prepubertal gymnasts. Thus, the premenarcheal status and a higher age at peak height velocity contribute to performance in Rhythmic Gymnastics.

scholarly journals Association Between Paternal Separation During Early Childhood and Pubertal Timing Among Girls Using Longitudinal Birth Cohort in Japan

2021 ◽  
Vol 12 ◽  
Author(s):  
Aomi Katagiri ◽  
Nobutoshi Nawa ◽  
Takeo Fujiwara
Keyword(s):  
Early Childhood ◽  
Confidence Interval ◽  
Pubertal Timing ◽  
Pubertal Development ◽  
Divorce Rate ◽  
Peak Height ◽  
Longitudinal Survey ◽  
Height Velocity ◽  
Peak Height Velocity ◽  
Paternal Absence

IntroductionPrevious studies have shown that paternal absence leads to earlier pubertal timing among girls in high-income countries. Despite the low divorce rate in Japan, paternal separation is commonly seen due to a unique corporation system, tanshin funin, where employees relocate with their spouses and children. We examined paternal separation, including paternal absence (due to divorce or paternal death) and paternal tanshin funin, during early childhood as a predictor of earlier girl’s pubertal development, assessed as age at peak height velocity (PHV).MethodsThis study examined 15 214 girls from a longitudinal survey conducted in Japan from 2001 to 2016 by the Ministry of Health, Labor and Welfare. Paternal separation was determined by the occurrence through annual surveys conducted at ages 0.5 to 4.5 years. Outcome was defined as age at PHV between ages 6 to 15 years. We conducted linear regression, adjusted for potential confounders and other covariates.ResultsContinuous father cohabitation was seen in 88.7% of households, while paternal separation was experienced 1-2, 3-4 and 5 times (always) among 7.4%, 2.8% and 1.1% of households, respectively. Girls who confronted continuous paternal separation (5 times) experienced 0.42 years earlier [95% confidence interval (CI): -0.75, -0.10] age at PHV compared to their peers who always lived with their fathers.ConclusionGirls who experienced paternal separation throughout ages 0.5 to 4.5 years experienced PHV earlier.

Pubertal Development of Young Association Football Players: A Longitudinal Study

1994 ◽  
Vol 6 (2) ◽  
pp. 140-148
Author(s):  
William Bell
Keyword(s):  
Pubertal Development ◽  
Normal Growth ◽  
Peak Height ◽  
Pubic Hair ◽  
Height Velocity ◽  
Control Group ◽  
Football Players ◽  
Peak Height Velocity ◽  
Association Football ◽  
Pubertal Stages

The purpose of the present study was to investigate the pubertal characteristics of a group of specialist association football (soccer) players (N = 22) between the ages of 12.3 and 15.3 years. Pubertal status was assessed by direct observation of pubic hair (PH), and peak height velocity (PHV) was assessed using graphic procedures. The ages at which the various stages of PH were reached did not differ between playing positions or between players as a whole and the control group. The length of the interval between sequential stages of PH was about a year and between PH2 and PH5 was 2.5 years. Correlations between the age at PHV and each of the pubertal stages were generally high. It was concluded that the influence of participation in competitive association football had no significant effect on the attainment and progress of pubertal development beyond that expected by normal growth.

scholarly journals Breakfast: A Crucial Meal for Adolescents’ Cognitive Performance According to Their Nutritional Status. The Cogni-Action Project

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1320
Author(s):  
Humberto Peña-Jorquera ◽  
Valentina Campos-Núñez ◽  
Kabir P. Sadarangani ◽  
Gerson Ferrari ◽  
Carlos Jorquera-Aguilera ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Cognitive Performance ◽  
Cognitive Demand ◽  
Positive Association ◽  
Peak Height ◽  
The Body ◽  
Height Velocity ◽  
Peak Height Velocity ◽  
High Quality ◽  
Action Project

This study aimed to determine whether pupils who have breakfast just before a cognitive demand, do not regularly skip breakfast, and consume a high-quality breakfast present higher cognitive performance than those who do not; furthermore, to establish differences according to their nutritional status. In this study, 1181 Chilean adolescents aged 10–14 years participated. A global cognitive score was computed through eight tasks, and the body mass index z-score (BMIz) was calculated using a growth reference for school-aged adolescents. The characteristics of breakfast were self-reported. Analyses of covariance were performed to determine differences in cognitive performance according to BMIz groups adjusted to sex, peak height velocity, physical fitness global score, and their schools. A positive association was found in adolescents’ cognitive performance when they had breakfast just before cognitive tasks, did not regularly skip breakfast, presented at least two breakfast quality components, and included dairy products. No significant differences were found between breakfast components, including cereal/bread and fruits/fruit juice. Finally, pupils who were overweight/obese who declared that they skipped breakfast regularly presented a lower cognitive performance than their normal-BMIz peers. These findings suggest that adolescents who have breakfast just prior to a cognitive demand and regularly have a high quality breakfast have better cognitive performance than those who do not. Educative nutritional strategies should be prioritized, especially in “breakfast skippers” adolescents living with overweight/obesity.

scholarly journals Growth in achondroplasia, from birth to adulthood, analysed by the JPA-2 model

2020 ◽  
Vol 33 (12) ◽  
pp. 1589-1595
Author(s):  
Mariana del Pino ◽  
Virginia Fano ◽  
Paula Adamo
Keyword(s):  
General Population ◽  
Growth Curve ◽  
Growth Velocity ◽  
Adult Height ◽  
Growth Curves ◽  
Peak Height ◽  
Height Growth ◽  
Individual Growth ◽  
Height Velocity ◽  
Peak Height Velocity

AbstractObjectivesIn general population, there are three phases in the human growth curve: infancy, childhood and puberty, with different main factors involved in their regulation and mathematical models to fit them. Achondroplasia children experience a fast decreasing growth during infancy and an “adolescent growth spurt”; however, there are no longitudinal studies that cover the analysis of the whole post-natal growth. Here we analyse the whole growth curve from infancy to adulthood applying the JPA-2 mathematical model.MethodsTwenty-seven patients, 17 girls and 10 boys with achondroplasia, who reached adult size, were included. Height growth data was collected from birth until adulthood. Individual growth curves were estimated by fitting the JPA-2 model to each individual’s height for age data.ResultsHeight growth velocity curves show that after a period of fast decreasing growth velocity since birth, with a mean of 9.7 cm/year at 1 year old, the growth velocity is stable in late preschool years, with a mean of 4.2 cm/year. In boys, age and peak height velocity in puberty were 13.75 years and 5.08 cm/year and reach a mean adult height of 130.52 cm. In girls, the age and peak height velocity in puberty were 11.1 years and 4.32 cm/year and reach a mean adult height of 119.2 cm.ConclusionsThe study of individual growth curves in achondroplasia children by the JPA-2 model shows the three periods, infancy, childhood and puberty, with a similar shape but lesser in magnitude than general population.

scholarly journals Biological maturity and the anthropometric, physical and technical assessment of talent identified U16 Australian footballers

2017 ◽  
Vol 12 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Ashley J Cripps ◽  
Christopher Joyce ◽  
Carl T Woods ◽  
Luke S Hopper
Keyword(s):  
Characteristic Curve ◽  
Vertical Jump ◽  
Binary Logistic Regression ◽  
Peak Height ◽  
Technical Skill ◽  
Height Velocity ◽  
State Representation ◽  
Peak Height Velocity ◽  
Biological Maturation ◽  
Australian Football

This study compared biological maturation, anthropometric, physical and technical skill measures between talent and non-talent identified junior Australian footballers. Players were recruited from the under 16 Western Australian Football League and classified as talent (state representation; n = 25, 15.7 ± 0.3 y) or non-talent identified (non-state representation; n = 25, 15.6 ± 0.4 y). Players completed a battery of anthropometric, physical and technical skill assessments. Maturity was estimated using years from peak height velocity calculations. Binary logistic regression was used to identify the variables demonstrating the strongest association with the main effect of ‘status’. A receiver operating characteristic curve was used to assess the level of discrimination provided by the strongest model. Talent identified under 16 players were biologically older, had greater stationary and dynamic leaps and superior handball skill when compared to their non-talent identified counterparts. The strongest model of status included standing height, non-dominant dynamic vertical jump and handball outcomes (AUC = 83.4%, CI = 72.1%–95.1%). Biological maturation influences anthropometric and physical capacities that are advantageous for performance in Australian football; talent identification methods should factor biological maturation as a confound in the search for junior players who are most likely to succeed in senior competition.

scholarly journals Somatic maturation and the relationship between bone mineral variables and types of sports among adolescents: cross-sectional study

2017 ◽  
Vol 135 (3) ◽  
pp. 253-259 ◽  
Author(s):  
Ricardo Ribeiro Agostinete ◽  
Igor Hideki Ito ◽  
Han Kemper ◽  
Carlos Marcelo Pastre ◽  
Mário Antônio Rodrigues-Júnior ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Peak Height ◽  
Cross Sectional Study ◽  
Height Velocity ◽  
Whole Body ◽  
Sectional Study ◽  
Peak Height Velocity ◽  
Mineral Density ◽  
Cross Sectional

ABSTRACT CONTEXT AND OBJECTIVE: Peak height velocity (PHV) is an important maturational event during adolescence that affects skeleton size. The objective here was to compare bone variables in adolescents who practiced different types of sports, and to identify whether differences in bone variables attributed to sports practice were dependent on somatic maturation status. DESIGN AND SETTING: Cross-sectional study, São Paulo State University (UNESP). METHODS: The study was composed of 93 adolescents (12 to 16.5 years old), divided into three groups: no-sport group (n = 42), soccer/basketball group (n = 26) and swimming group (n = 25). Bone mineral density and content were measured using dual-energy x-ray absorptiometry and somatic maturation was estimated through using peak height velocity. Data on training load were provided by the coaches. RESULTS: Adolescents whose PHV occurred at an older age presented higher bone mineral density in their upper limbs (P = 0.018). After adjustments for confounders, such as somatic maturation, the swimmers presented lower values for bone mineral density in their lower limbs, spine and whole body. Only the bone mineral density in the upper limbs was similar between the groups. There was a negative relationship between whole-body bone mineral content and the weekly training hours (β: -1563.967; 95% confidence interval, CI: -2916.484 to -211.450). CONCLUSION: The differences in bone variables attributed to sport practice occurred independently of maturation, while high training load in situations of hypogravity seemed to be related to lower bone mass in swimmers.

Effects of Drop Height on Jump Performance in Male and Female Elite Adolescent Handball Players

2019 ◽  
Vol 14 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Olaf Prieske ◽  
Helmi Chaabene ◽  
Christian Puta ◽  
David G. Behm ◽  
Dirk Büsch ◽  
...  
Keyword(s):  
Peak Height ◽  
Height Velocity ◽  
Medium Size ◽  
Drop Height ◽  
Peak Height Velocity ◽  
Adolescent Athletes ◽  
Male And Female ◽  
Standing Long Jump ◽  
Long Jump ◽  
Split Time

Purpose: To examine the effects of drop height on drop-jump (DJ) performance and on associations between DJ and horizontal-jump/sprint performances in adolescent athletes. Methods: Male (n = 119, 2.5 [0.6] y post-peak-height velocity) and female (n = 120, 2.5 [0.5] y post-peak-height velocity) adolescent handball players (national level) performed DJs in randomized order using 3 drop heights (20, 35, and 50 cm). DJ performance (jump height, reactive strength index [RSI]) was analyzed using the Optojump Next system. In addition, correlations were computed between DJ height and RSI with standing-long-jump and 20-m linear-sprint performances. Results: Statistical analyses revealed medium-size main effects of drop height for DJ height and RSI (P < .001, 0.63 ≤ d ≤ 0.71). Post hoc tests indicated larger DJ heights from 20 to 35 and 35 to 50 cm (P ≤ .031, 0.33 ≤ d ≤ 0.71) and better RSI from 20- to 35-cm drop height (P < .001, d = 0.77). No significant difference was found for RSI between 35- and 50-cm drop height. Irrespective of drop height, associations of DJ height and RSI were small with 5-m-split time (−.27 ≤ r ≤ .05), medium with 10-m-split time (−.44 ≤ r ≤ .14), and medium to large with 20-m sprint time and standing-long-jump distance (−.57 ≤ r ≤ .22). Conclusions: The present findings indicate that, irrespective of sex, 35-cm drop heights are best suited to induce rapid and powerful DJ performance (ie, RSI) during reactive strength training in elite adolescent handball players. Moreover, training-related gains in DJ performance may at least partly translate to gains in horizontal jump and longer sprint distances (ie, ≥20-m) and/or vice versa in male and female elite adolescent athletes, irrespective of drop height.

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