scholarly journals Age-Related Perception of Stature, Acceptance of Therapy, and Psychosocial Functioning in Human Growth Hormone-Treated Girls with Turner’s Syndrome1

1998 ◽  
Vol 83 (5) ◽  
pp. 1494-1501 ◽  
Author(s):  
Katrien Lagrou ◽  
Danielle Xhrouet-Heinrichs ◽  
Claudine Heinrichs ◽  
Margarita Craen ◽  
Jean-Pierre Chanoine ◽  
...  
Keyword(s):  
Psychosocial Functioning ◽  
Growth Response ◽  
Self Esteem ◽  
Attention Problems ◽  
Self Report ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Gh Therapy ◽  
Group A ◽  
Group B

This study evaluated the perception of stature, acceptance of therapy, and psychosocial functioning in relation to age at onset and time on treatment during 2 yr of GH therapy in 31 girls with Turner’s syndrome grouped by age (group A: 3.7–5.8 yr, n = 9; group B: 7.2–11.8 yr, n = 13; group C: 12.5–16.4 yr, n = 9). The growth response after 2 yr was significant in the 3 groups when calculated in terms of growth norms for untreated Turner girls (mean increase in height sd score: +1.2, +1.5, and +1.1, respectively). The effect was less marked in terms of growth norms for normal girls, particularly in group B (+0.5 sd score). Height was perceived as a problem by most patients, except in the youngest girls at the start of treatment (group A) and in the majority of the adolescents after 2 yr of GH therapy (group C), without evidence of relation to growth response during therapy. The GH injections were fairly well accepted by all patients, except those younger than 6 yr. In all patients, expected adult height was unrealistic and became more realistic with age, whereas no consistent changes were observed in relation to growth response to GH therapy. The Child Behavior Checklist revealed elevated mean scores at the behavioral subscales of attention problems (group A and B), social problems, withdrawal, and anxiety-depression (most obviously in group B). No significant changes were seen during GH therapy. In group C, an elevated mean social problem score at the Youth Self Report and a low mean social self-esteem score at the Self-Esteem Inventory were observed before therapy and showed a significant improvement during 2 yr of GH treatment. These results, however, might be biased due to an increase in social desirability during therapy. We conclude that the perception of height, acceptance of GH therapy, and psychosocial functioning in girls with Turner’s syndrome show important differences between age groups, with only slight changes observed during GH therapy.

Effect on growth of patients with Turner's syndrome treated with low estrogen doses

1986 ◽  
Vol 113 (4_Suppl) ◽  
pp. S153-S156 ◽  
Author(s):  
MICHAEL B. RANKE ◽  
FRANK HAUG ◽  
WERNER F. BLUM ◽  
WERNER ROSENDAHL ◽  
ANDREA ATTANASIO ◽  
...  
Keyword(s):  
Bone Age ◽  
Height Velocity ◽  
Turner's Syndrome ◽  
Low Doses ◽  
Turner’S Syndrome ◽  
Control Data ◽  
End Of Treatment ◽  
Group A ◽  
One Year ◽  
Group B

ABSTRACT In 33 patients with Turner's syndrome growth during a one year period of treatment with low doses of estrogens was evaluated (group A: (N=12) PresomenR 5–9 μg/kg d; group B: (N=9) PresomenR 10–21 μg/kg d; group C: (N=12) ethinylestradiol 45–155 ng/kg d) and compared to a group (N=37) of untreated patients. The auxological evaluation was made using SDS derivations based on control data derived from 150 untreated patients. Based on chronological age (CA) SDS levels for height velocity and the increments in height at the end of treatment increased marginally. Compared to untreated patients no effect was seen when calculations were based on bone age (BA) due to an advancement in bone maturity. It is concluded that low doses of estrogens are not suitable to improve the height development in Turner's syndrome.

scholarly journals Blood asymmetric dimethylarginine and nitrite/nitrate concentrations in short-stature children born small for gestational age with and without growth hormone therapy

2017 ◽  
Vol 46 (2) ◽  
pp. 761-772 ◽  
Author(s):  
Hironori Nagasaka ◽  
Ichiro Morioka ◽  
Mayuko Takuwa ◽  
Mariko Nakacho ◽  
Mayumi Yoshida ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Growth Hormone ◽  
Asymmetric Dimethylarginine ◽  
Therapy Group ◽  
Adma Level ◽  
Gh Therapy ◽  
Normal Children ◽  
Group A ◽  
Group B ◽  
Nitrite Nitrate

Objective To investigate the basal amino acid metabolism and impact of growth hormone (GH) therapy in short-stature children born small for gestational age (short SGA children). Methods In this age-matched case-control study, the basal blood levels of amino acids, asymmetric dimethylarginine (ADMA), and nitrite/nitrate (NOx) were compared between 24 short SGA children and 25 age-matched normal children. Changes in these parameters were assessed for 12 months in 12 short SGA children initiating GH therapy (Group A) and 12 age-matched short SGA children without GH therapy (Group B). Results The arginine levels were significantly lower in the short SGA than in normal children. The ADMA levels were significantly higher and NOx levels were significantly lower in the short SGA than normal children. In Group A, the ADMA level was significantly lower and NOx level was significantly higher at 6 months than at baseline. At 12 months, the ADMA level in Group A began to increase, but the NOx level remained the same. Group B showed no significant changes. Conclusions This study is the first to show that ADMA is promoted and nitric oxide is suppressed in short SGA children and that GH therapy affects the production of ADMA and nitric oxide.

scholarly journals Effects of Direct-Acting Antiviral Agents on the Mental Health of Patients with Chronic Hepatitis C: A Prospective Observational Study

2020 ◽  
Vol 10 (8) ◽  
pp. 483
Author(s):  
Michele Fabrazzo ◽  
Rosa Zampino ◽  
Martina Vitrone ◽  
Gaia Sampogna ◽  
Lucia Del Gaudio ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Self Report ◽  
Psychiatric History ◽  
Direct Acting Antiviral ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Direct Acting

In chronic hepatitis C (CHC) patients, interferon-based treatments showed toxicity, limited efficacy, and psychiatric manifestations. Direct-acting antiviral (DAA) agents appeared safer, though it remains unclear if they may exacerbate or foster mood symptoms in drug-naïve CHC patients. We evaluated 62 CHC patients’ mental status, before and 12 weeks after DAA therapy, by assessment scales and psychometric instruments. We subdivided patients into two groups, CHC patients with (Group A) or without (Group B) a current and/or past psychiatric history. After DAA treatment, Group A patients showed low anxiety and improved depression, no variation in self-report distress, but worse general health perceptions. No significant difference emerged from coping strategies. Depression and anxiety improved in Group B, and no change emerged from total self-reported distress, except for somatization. Moreover, Group B increased problem-focused strategies for suppression of competing activities, and decreased strategies of instrumental social support. Contrarily, Group B reduced significantly emotion-focused strategies, such as acceptance and mental disengagement, and improved vitality, physical and social role functioning. DAA therapy is safe and free of hepatological and psychiatric side effects in CHC patients, regardless of current and/or past psychiatric history. In particular, patients without a psychiatric history also remarkably improved their quality of life.

scholarly journals Effect of Low-Energy Shockwave Therapy Versus Platelets Rich Plasma Therapy in Patients with Erectile Dysfunction

2021 ◽  
pp. 168-172
Author(s):  
Kumail Sajjad ◽  
Muhammad Sohail ◽  
Hafiz Abdul Momin ◽  
Raja Asim Shafique ◽  
Muhammad Nazir ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Platelet Rich Plasma ◽  
Self Esteem ◽  
Low Energy ◽  
Plasma Therapy ◽  
Shockwave Therapy ◽  
Group A ◽  
Group B ◽  
Near Future ◽  
Phosphodiesterase 5

Phosphodiesterase 5 inhibitors (PDE5Is) and low-energy shock wave therapy (LESWT) have created a revolution in the treatment of erectile dysfunction (ED).  However, they are not able to restore the actual changes in the penis. An emerging new therapy called platelet-rich plasma (PRP) is believed to be more beneficial in treating ED.  The objective of this study is to evaluate and compare the efficacy of LESWT and PRP in treating ED. A total of sixty participants of pathological ED was included in the study and divided into two groups. Group A received the LESWT, whereas Group B received the PRP. The benefits were measured by the International Index of Erectile Function (IIEF), an erection hardness score (EHS) and Self-Esteem And Relationship (SEAR) questionnaires. The results of this analysis demonstrated a larger effect in treatment group B in percentage terms, but there were no statistical differences in the two groups. In the near future, PCP may be a new modality for treating ED, especially PDE5I non-respondents with organic ED. However, more extensive preclinical and applied research needs to be conducted.

scholarly journals A comparison of self-esteem between patients undergoing fixed orthodontic treatment, to those not receiving orthodontic treatment

2021 ◽  
Vol 7 (4) ◽  
pp. 112-115
Author(s):  
Maleeha Majid ◽  
◽  
Maliha Jamshaid ◽  
Ghina Rizwan ◽  
Zarnab Rizwan ◽  
...  
Keyword(s):  
Sample Size ◽  
Orthodontic Treatment ◽  
Self Esteem ◽  
The Self ◽  
The Other ◽  
Treatment Need ◽  
The Past ◽  
Group A ◽  
And Gender ◽  
Group B

Objective: Comparison of the self-esteem between patients undergoing fixed orthodonticc treatment in the past 6 months or more, to those not receiving orthodontic treatment or the time passed since the commencement of their treatment has been less than six months. Materials and methods: The participants of this study were divided into two groups, group A and group B. The sample size of each group was 75 making the total 150 aged between 16 to 25 years. The malocclusion severity was assessed with the index of orthodontic treatment need aesthetic component (IOTN-AC) which was 6 or more for both groups. Group A involved patients currently receiving no orthodontic treatment or the time elapsed since the start of the treatment was less than 6 months. Group B on the other hand, comprised of patients undergoing orthodontic treatment in the past 6 months or more. Questionnaires were administered among both group A and group B where self-esteem was measured using the Rosenberg Self-esteem (RSE) Scale. Independent Sample T test was applied on both of these variables. Results: The results did not show any statistically significant association between self-esteem and “the time elapsed since the start of the treatment”. Likewise, the additional factors i.e., Age, Education and Gender too had no impact on the Rosenberg score. Conclusion: No association was found between selfesteem of the patients undergoing fixed Orthodontic treatment, to those not receiving it

Self-estimation of phenylketonuria patients on therapeutic diet. Psychological support

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Kostas Konstantinos Iakovou ◽  
Kleopatra Schulpis
Keyword(s):  
Support Group ◽  
Self Esteem ◽  
Psychological Support ◽  
The Self ◽  
Self Concept ◽  
Group A ◽  
Group B ◽  
Very High

AbstractObjectivesSelf-esteem is the degree to which the qualities and characteristics contained in one’s self-concept are perceived to be positive. The aim of this study was to evaluate the self-esteem scores in phenylketonuria (PKU) patients on “strict”, “loos” and “off diet”. Sixty PKU patients were divided in three equal groups.MethodsGroup a: “on strict”, group b: “on loos” and group c: “off diet”. A special questionnaire for self-esteem scores was created for these patients.ResultsBefore psychological support, group a patients demonstrated 6/20 (30%) very high self-esteem, 9/20 (45%) high and 5/25 (25%) moderate. After support 14/20 (70%) were turned to very high, 5/20 (25%) represented high except one whose degrees remained an altered. group b 4/20 (20%) were very high, 7/20 (35%) were high, 3/20 (15%) moderate and the rest of them showed low self-esteem degrees, after support, 10/20 (50%) showed very high, 5/20 (25%) became high, 3/20 (15%) turned to moderate and 2/20 (10%) remained unaltered. Group c, 1/20 (5%) were very high self-esteemed, 7/20 (35%) were high, 6/20 (30%) were moderate and 6/20 (30%) with low self-esteemed, at the end of support, 6/20 (30%) become very high, 8/20 (40%) with high, 4/20 (20.0%), moderate self-esteem whereas the rest were unaltered.ConclusionsVery high and high self-esteem degrees were demonstrated in patients who follow their PKU diet. Moderate and low self-esteem degrees were predominantly found in patients on loos and or off diet. Psychological supports commonly result in amelioration of self-esteem degrees.

scholarly journals Type of Physical Training and Selected Aspects of Psychological Functioning of Women with Obesity: A Randomised Trial

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2555
Author(s):  
Monika Bąk-Sosnowska ◽  
Magdalena Gruszczyńska ◽  
Damian Skrypnik ◽  
Sławomir Grzegorczyn ◽  
Joanna Karolkiewicz ◽  
...  
Keyword(s):  
Strength Training ◽  
Endurance Training ◽  
Physical Training ◽  
Body Shape ◽  
Randomised Trial ◽  
Training Group ◽  
Self Report ◽  
Endurance Strength ◽  
Group A ◽  
Group B

Objective: We conducted a prospective randomised trial to assess whether a specific type of regular physical training performed by women with obesity is related to obtaining specific psychological benefits. Methods: Forty-four women qualified for the study and were divided into two groups. The applied intervention consisted of regular three-month physical exercises in the form of endurance training (group A) or endurance strength training (group B). Initially, and after the completed intervention, we examined anthropometric measurements and the level of: stress (PSS-10), general self-esteem (SES), body self-report (BSQ–34, FRS), and behaviours associated with diet (TFEQ-18). Results: As a result of the intervention, both groups had significantly lower anthropometric parameters and FRS scores with regard to the current figure (gr. A:δ FRS CS −0.90 ± 0.83, p < 0.001; gr. B:δ FRS CS −0.41 ± 0.50, p = 0.01) and BSQ–34 results (gr. A:δ BSQ–34 −14.90 ± 13.5, p = 0.001; gr. B:δ BSQ–34 − 18.64 ± 25.4, p = 0.01). Additionally, an increase in cognitive restraint (δ TFEQ–18 CR1.65 ± 2.06, p = 0.01) and a decrease in emotional eating (δ TFEQ–18 EE −0.82 ± 1.28, p = 0.01) were observed in group B. There were no between-group differences in terms of the magnitude of changes achieved due to the intervention, except for asignificant improvement in the perception of their current figure (FRS) (δ FRSCS −0.90 ± 0.83, p = 0.03) in group A. Conclusions: Regular physical activity over a three-month period by women with obesity promotes the perception of their own body as slimmer and lowers body shape concerns. The change in body shape perception was more pronounced under the influence of endurance training than endurance strength training. Trial registration: ClinicalTrials.gov ID NCT04793451.

scholarly journals Social Support and Appearance Satisfaction Can Predict Changes in the Psychopathology Levels of Patients with Acne, Psoriasis and Eczema, before Dermatological Treatment and in a Six-Month Follow-up Phase

Psych ◽  
2021 ◽  
Vol 3 (3) ◽  
pp. 259-268
Author(s):  
Charalambos Costeris ◽  
Maria Petridou ◽  
Yianna Ioannou
Keyword(s):  
Social Support ◽  
Skin Condition ◽  
Cross Sectional Study ◽  
Self Report ◽  
Cross Sectional ◽  
Appearance Satisfaction ◽  
Group A ◽  
Group B ◽  
Body Self

This was a cross-sectional study which assessed the factors that predicted changes in the levels of psychopathological symptomatology of patients with acne, psoriasis and eczema both before dermatological treatment and in a six-month follow-up phase. One hundred and eight dermatological patients (18–35 years) participated in the study; 54 with visible facial cystic acne (Group A), and 54 with non-visible psoriasis/eczema (Group B). A battery of self-report questionnaires were administered to all patients before their dermatological treatment and in a six-month follow-up phase and included: the Symptom Checklist-90 Revised (SCL-90-R), the Interpersonal Support Evaluation List (ISEL-40), the Multidimensional Body–Self Relations Questionnaire (MBSRQ–AS) and the Rosenberg Self-Esteem Scale. Multiple regression analyses revealed that patients’ overall perceived social support and overall appearance satisfaction appeared to be strong predictors of the maintenance of patients’ psychopathology levels, even six months after they began their dermatological treatment. Psychosocial factors such as patients’ social support and appearance satisfaction could influence their psychopathology levels and the way they experienced their skin condition, before treatment and after a six-month period of time. The psychological assessment of the aforementioned factors could detect patients who would benefit from psychotherapeutic interventions in order to help them adapt to the extra burden which accompanies dermatological disorders.

scholarly journals The Reliability and Agreement of the Fibromyalgia Survey Questionnaire in an Italian Sample of Obese Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Giorgia Varallo ◽  
Ada Ghiggia ◽  
Marco Arreghini ◽  
Paolo Capodaglio ◽  
Gian Mauro Manzoni ◽  
...  
Keyword(s):  
The Self ◽  
Self Report ◽  
Obese Patients ◽  
Survey Questionnaire ◽  
Altman Analysis ◽  
Bland Altman Analysis ◽  
Fast Screening ◽  
Group A ◽  
Group B ◽  
Italian Sample

The Fibromyalgia Survey Questionnaire (FSQ) was self-administered by a sample of 207 Italian individuals with obesity to screen for fibromyalgia (FM). We aimed to investigate the inter-rater reliability and the agreement in the detection of FM symptomatology between the self-administered FSQ and the clinical interview conducted by a rheumatologist. All the patients were divided randomly into two groups (group A and group B): a rheumatologist first interviewed patients of group A and after 48 h, the patients completed the self-report FSQ. Patients of group B first completed the FSQ and 48 h later were interviewed by a rheumatologist. The agreement between the measurements was good with the Bland-Altman analysis showing low bias scores for the two subscales of the FSQ. Results showed that 33% of the sample satisfied the criteria for a diagnosis of fibromyalgia. The FSQ is a self-reporting measure that showed substantial reliability providing fast screening for FM symptomatology.

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