scholarly journals Do Pre-operative Activity Levels Affect Long Term Meniscectomy Outcomes?

2021 ◽  
Vol 53 (8S) ◽  
pp. 392-392
Author(s):  
Susan Y. Kwiecien ◽  
Lee Bloom ◽  
Rachel E. Kessler ◽  
Erin E. Nicholas ◽  
Emily K. Kolodka ◽  
...  
1986 ◽  
Vol 21 (3) ◽  
pp. 211-225 ◽  
Author(s):  
David Licht ◽  
John B. Morganti ◽  
Milton F. Nehrke ◽  
Gary Heiman

Conflicting interpretations questioning whether brief intervals of real time are perceived as passing more or less rapidly with increasing age have been reported. Reasons for these inconsistent results lie in semantic confusions, in variations in methodology, and in the effects of other mediating variables. The present study examined relationships between age, value of time over both the short and the long term, perceived time to death, self-perceived activity levels, and estimates of brief time intervals in a sample of older institutionalized males. The production method was used to obtain the estimates of time passage. Time intervals were increasingly underestimated with advancing age, indicating that time units are shorter with increasing age. While a number of other variables were interrelated, the only other factor consistently related to time estimates was the short-term value of time. Implications for future research and for interventions in institutional settings are discussed.


2020 ◽  
Author(s):  
Alix Chadwell ◽  
Laura Diment ◽  
Encarna Micó Amigo ◽  
Dafne Zuleima Morgado Ramirez ◽  
Alexander Dickinson ◽  
...  

BackgroundUnderstanding how prostheses are used in everyday life is central to the design, provision and evaluation of prosthetic devices and associated services. This paper reviews the scientific literature on methodologies and technologies that have been used to assess the daily use of both upper- and lower-limb prostheses. It discusses the types of studies that have been undertaken, the technologies used to monitor physical activity, the benefits of monitoring daily living and the barriers to long-term monitoring.MethodsA systematic literature search was conducted in PubMed, Web of Science, Scopus, CINAHL and EMBASE of studies that monitored the activity of prosthesis-users during daily-living.Results60 lower-limb studies and 9 upper-limb studies were identified for inclusion in the review. The first studies in the lower-limb field date from the 1990s and the number has increased steadily since the early 2000s. In contrast, the studies in the upper-limb field have only begun to emerge over the past few years. The early lower-limb studies focused on the development or validation of actimeters, algorithms and/or scores for activity classification. However, most of the recent lower-limb studies used activity monitoring to compare prosthetic components. The lower-limb studies mainly used step-counts as their only measure of activity, focusing on the amount of activity, not the type and quality of movements. In comparison, the small number of upper-limb studies were fairly evenly spread between development of algorithms, comparison of everyday activity to clinical scores, and comparison of different prosthesis user populations. Most upper-limb papers reported the degree of symmetry in activity levels between the arm with the prosthesis and the intact arm.ConclusionsActivity monitoring technology used in conjunction with clinical scores and user feedback, offers significant insights into how prostheses are used and whether they meet the user’s requirements. However, the cost, limited battery-life and lack of availability in many countries mean that using sensors to understand the daily use of prostheses and the types of activity being performed has not yet become a feasible standard clinical practice. This review provides recommendations for the research and clinical communities to advance this area for the benefit of prosthesis users.


2019 ◽  
Vol 18 ◽  
Author(s):  
José Maciel Caldas dos Reis ◽  
Lauro José Mendes Queiroz ◽  
Pablo Ferreira Mello ◽  
Renan Kleber Costa Teixeira ◽  
Fábio de Azevedo Gonçalves

Abstract Acute compartment syndrome of the lower extremities after urological surgery in the lithotomy position is a rare but potentially devastating clinical and medicolegal problem. We report the case of a 67-year-old male who underwent laparoscopic prostatectomy surgery to treat cancer, spending 180 minutes in surgery. Postoperatively, the patient developed acute compartment syndrome of both legs, needing emergency bilateral four-compartment fasciotomies, with repeated returns to the operating room for second-look procedures. The patient also exhibited delayed wound closure. He regained full function within 6 months, returning to unimpaired baseline activity levels. This report aims to highlight the importance of preoperative awareness of this severe complication which, in conjunction with early recognition and immediate surgical management, may mitigate long-term adverse sequelae and improve postoperative outcomes.


2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Pratiksha Poudel ◽  
Kamila Ismailova ◽  
Lars Bo Andersen ◽  
Sofus C. Larsen ◽  
Berit L. Heitmann

Abstract Background Several studies have suggested a link between the type of alcoholic beverage consumption and body weight. However, results from longitudinal studies have been inconsistent, and the association between adolescent alcohol consumption long-term weight gain has generally not been examined. Methods The study was based on data from 720 Danish adolescents aged between 15 to 19 years at baseline from the Danish Youth and Sports Study (YSS). Self-reported alcohol use, height, weight, smoking, social economic status (SES) and physical activity levels were assessed in baseline surveys conducted in 1983 and 1985, and in the follow up survey which was conducted in 2005. Multiple linear regression analyses were used to examine the association between alcohol consumption in adolescence and subsequent weight gain later in midlife. Results There was no significant association between total alcohol consumption during adolescence and change in BMI into midlife (P = 0.079) (β − 0.14; 95% CI -0.28, 0.005). Wine consumption was found to be inversely associated to subsequent BMI gain (P = 0.001) (β − 0.46; 95% CI -0.82, − 0.09) while the results were not significant for beer and spirit. The relationship did not differ by gender, but smoking status was found to modify the relationship, and the inverse association between alcohol and BMI gain was seen only among non-smokers (P = 0.01) (β − 0.24; 95% CI -0.41, − 0.06) while no association was found among smokers. Neither adolescent nor attained socioeconomic status in adulthood modified the relationship between alcohol intake and subsequent BMI gain. Conclusion Among non-smoking adolescents, consumption of alcohol, and in particular wine, seems to be associated with less weight gain until midlife. Trial registration The YSS cohort was retrospectively registered on August 2017. (Study ID number: NCT03244150).


2008 ◽  
Vol 28 (21) ◽  
pp. 6668-6680 ◽  
Author(s):  
Albertus T. J. Wierenga ◽  
Edo Vellenga ◽  
Jan Jacob Schuringa

ABSTRACT The level of transcription factor activity critically regulates cell fate decisions, such as hematopoietic stem cell (HSC) self-renewal and differentiation. We introduced STAT5A transcriptional activity into human HSCs/progenitor cells in a dose-dependent manner by overexpression of a tamoxifen-inducible STAT5A(1*6)-estrogen receptor fusion protein. Induction of STAT5A activity in CD34+ cells resulted in impaired myelopoiesis and induction of erythropoiesis, which was most pronounced at the highest STAT5A transactivation levels. In contrast, intermediate STAT5A activity levels resulted in the most pronounced proliferative advantage of CD34+ cells. This coincided with increased cobblestone area-forming cell and long-term-culture-initiating cell frequencies, which were predominantly elevated at intermediate STAT5A activity levels but not at high STAT5A levels. Self-renewal of progenitors was addressed by serial replating of CFU, and only progenitors containing intermediate STAT5A activity levels contained self-renewal capacity. By extensive gene expression profiling we could identify gene expression patterns of STAT5 target genes that predominantly associated with a self-renewal and long-term expansion phenotype versus those that identified a predominant differentiation phenotype.


2015 ◽  
Vol 12 (8) ◽  
pp. 1128-1132 ◽  
Author(s):  
Marie-Louise Bird ◽  
Cecilia Shing ◽  
Casey Mainsbridge ◽  
Dean Cooley ◽  
Scott Pedersen

Background:Sedentary behavior is related to metabolic syndrome and might have implications for the long-term health of workers in a low activity environment. The primary aim of this pilot study was to determine activity levels of adults working at a University during work hours. A secondary aim was to determine the relationship between actual and perceived activity levels.Methods:Activity levels of university staff (n = 15, male = 7, age = 53 ± 7 years, BMI = 26.5 ± 2.5kg·m2) were monitored over 5 consecutive workdays using SenseWear accelerometers, then participants completed a questionnaire of their perception of workplace sedentary time.Results:Each participant spent 71.5 ± 13.1% (358 ± 78 min) of their workday being sedentary (< 1.5 METs), 15.6 ± 9.0% involved in light activity (1.5–3 METs), 11.7 ± 10.0% in moderate activity (3–5 METs), and 1.1 ± 1.3% in vigorous activity (> 5 METs) (P < .0001). The mean difference between actual (SenseWear < 1.5 METs) and perceived sitting time was –2 ± 32%; however, perceived sedentary time was reported with a range of under-to-over estimation of –75% to 51%.Conclusion:This pilot study identifies long periods of low metabolic activity during the workday and poor perception of individual sedentary time. Interventions to reduce sedentary time in the workplace may be necessary to ensure that the work environment does not adversely affect long-term health.


1994 ◽  
Vol 12 (10/11) ◽  
pp. 1065-1070 ◽  
Author(s):  
V. Mussino ◽  
O. Borello Filisetti ◽  
M. Storini ◽  
H. Nevanlinna

Abstract. Monthly averages of the Helsinki Ak-values have been reduced to the equivalent aa-indices to extend the aa-data set back to 1844. A periodicity of about five cycles was found for the correlation coefficient (r) between geomagnetic indices and sunspot numbers for the ascending phases of sunspot cycles 9 to 22, confirming previous findings based on a minor number of sunspot cycles. The result is useful to researchers in topics related to solar-terrestrial physics, particularly for the interpretation of long-term trends in geomagnetic activity during the past, and to forecast geomagnetic activity levels in the future.


2018 ◽  
Vol 29 (1) ◽  
pp. 68-74 ◽  
Author(s):  
Micheal Raad ◽  
Brian J. Neuman ◽  
Amit Jain ◽  
Hamid Hassanzadeh ◽  
Peter G. Passias ◽  
...  

OBJECTIVEGiven the recent shift in health care toward quality reporting requirements and a greater emphasis on a cost-quality approach, patient stratification with respect to long-term outcomes and the use of health care resources is of increasing value. Stratification tools may be effective if they are simple and evidence based. The authors hypothesize that preoperative patient-reported activity levels might independently predict postoperative outcomes in patients with adult spinal deformity.METHODSThis is a retrospective cohort. A total of 575 patients in a prospective adult spinal deformity surgical database were identified with complete data regarding the preoperative level of activity. Answers to question 5 of the Scoliosis Research Society-22r Patient Questionnaire (SRS-22r) were used to stratify patients into active and inactive groups. Outcomes were length of hospital stay (LOS), level of activity, and reaching the minimum clinically important difference (MCID) for SRS-22r domains and the Physical Component Summary (PCS) of the SF-36 at 2 years postoperatively. The 2 groups were compared with respect to several potential confounders. Covariates with p < 0.1 were controlled for. The impact of activity on LOS was assessed using multivariate negative binomial regression analysis. Multivariate logistic regression models additionally controlling for the respective baseline health-related quality of life (HRQOL) scores were used to assess the association between preoperative activity levels and reaching the MCID at 2 years postoperatively.RESULTSA total of 420 (73%) of the 575 patients who met the inclusion criteria had complete data at 2 years postoperatively. The inactive group was more likely to be significantly older, have a higher Charlson Comorbidity Index, worse baseline radiographic deformity, and greater correction of most radiographic parameters. After controlling for possible confounders, the active group had a significantly shorter LOS (incidence risk ratio 0.91, p = 0.043). After adding respective baseline HRQOL scores to the models, active patients were significantly more likely to reach the MCID for the SRS-22r pain domain (OR 1.72, p = 0.026) and PCS (OR 1.94, p = 0.013). Active patients were also significantly more likely to be active at 2 years postoperatively on multivariate analysis (OR 8.94, p < 0.001).CONCLUSIONSThe authors’ results show that patients who belong to the inactive group are likely to have a longer LOS and lower odds of reaching the MCID in HRQOL or being active at 2 years postoperatively. Inquiring about patients’ preoperative activity levels might be a reliable and simple stratification tool in terms of long- and short-term outcomes in ASD patients.


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