scholarly journals Influenza season - is there anything to worry about?

2021 ◽  
Vol 11 (9) ◽  
pp. 781-797
Author(s):  
Maciej Dubaj ◽  
Katarzyna Słomczyńska ◽  
Marta Karczmarczyk
Keyword(s):  
Infectious Disease ◽  
Influenza Virus ◽  
Influenza Season ◽  
Daily Activities ◽  
Annual Increase ◽  
Scientific Databases ◽  
The World ◽  
Acute Infectious Disease ◽  
Life Threatening ◽  
The Individual

Influenza (the flu) is an acute infectious disease caused by viruses of the Orthomyxoviridae family, causing a wide variety of symptoms in humans, ranging from mildly disturbing daily activities to life-threatening pneumonia, depending on the state of their immune system. The annual increase in the incidence of this disease is called "the flu season", which is a periodic epidemic that affects people all around the world. Despite the individual, economic and epidemiological risks associated with infection with the influenza virus, the disease is often underestimated by people. The aim of this study was to present influenza as a threat to the health of individuals and society by describing the pathomechanisms of its formation and spread, available diagnostic and therapeutic options, as well as annual vaccinations as the most effective method of disease prevention. The current publications available in online scientific databases from many countries around the world were reviewed. Despite the large number of widely available research results on influenza, it is necessary to update them every year, as well as vaccines against this disease, to popularize knowledge about it, which will enable more effective epidemiological control of influenza.

scholarly journals COVID-19 and Thrombosis Predisposition

2020 ◽  
Vol 5 (3) ◽  
pp. 86-90
Author(s):  
Renata Gerculy ◽  
Camelia Libenciuc ◽  
Nora Rat ◽  
Monica Chitu ◽  
Imre Benedek
Keyword(s):  
Infectious Disease ◽  
Current Knowledge ◽  
The Novel ◽  
Coagulation Disorders ◽  
Healthy Individuals ◽  
The World ◽  
Life Threatening ◽  
Thrombotic Complications ◽  
Disease Spreading ◽  
Novel Coronavirus

AbstractThe novel coronavirus disease first appeared in Wuhan (China) is an infectious disease spreading throughout the world, causing life-threatening conditions in vulnerable or even healthy individuals. The great impact of this virus on healthcare urges physicians to investigate all aspects of the disease in order to overcome its complications. A particularly investigated aspect of the SARS-CoV-2 infection is represented by the coagulation disorders among infected and critically ill patients. Several studies observed modified blood coagulation parameters such as D-dimers, fibrinogen, and coagulation times. Moreover, the severe thrombotic complications, mainly pulmonary embolism, could be responsible for the high mortality and poorer outcomes of COVID-19 infected patients. The aim of this article is to present the current knowledge related to thrombosis predisposition in patients infected with the new coronavirus.

scholarly journals Very little influenza in the WHO European Region during the 2020/21 season, weeks 40 2020 to 8 2021

2021 ◽  
Vol 26 (11) ◽  
Author(s):  
Cornelia Adlhoch ◽  
Piers Mook ◽  
Favelle Lamb ◽  
Lisa Ferland ◽  
Angeliki Melidou ◽  
...  
Keyword(s):  
Public Health ◽  
Influenza Virus ◽  
Seasonal Influenza ◽  
Influenza Season ◽  
World Health ◽  
European Region ◽  
Influenza Epidemic ◽  
The World ◽  
Health Organization ◽  
Viral Subtypes

Between weeks 40 2020 and 8 2021, the World Health Organization European Region experienced a 99.8% reduction in sentinel influenza virus positive detections (33/25,606 tested; 0.1%) relative to an average of 14,966/39,407 (38.0%; p < 0.001) over the same time in the previous six seasons. COVID-19 pandemic public health and physical distancing measures may have extinguished the 2020/21 European seasonal influenza epidemic with just a few sporadic detections of all viral subtypes. This might possibly continue during the remainder of the influenza season.

scholarly journals The Symmetric Difference Distance: A New Way to Evaluate the Evolution of Interfaces along Molecular Dynamics Trajectories; Application to Influenza Hemagglutinin

Symmetry ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 662
Author(s):  
Valentin Ozeel ◽  
Aurélie Perrier ◽  
Anne Vanet ◽  
Michel Petitjean
Keyword(s):  
Infectious Disease ◽  
Molecular Dynamics ◽  
Influenza Virus ◽  
Molecular Dynamics Simulation ◽  
Dynamics Simulation ◽  
Symmetric Difference ◽  
Influenza Hemagglutinin ◽  
Spatial Alignment ◽  
The World ◽  
Seasonal Epidemics

We propose a new and easy approach to evaluate structural dissimilarities between frames issued from molecular dynamics, and we test this methodology on human hemagglutinin. This protein is responsible for the entry of the influenza virus into the host cell by endocytosis, and this virus causes seasonal epidemics of infectious disease, which can be estimated to result in hundreds of thousands of deaths each year around the world. We computed the three interfaces between the three protomers of the hemagglutinin H1 homotrimer (PDB code: 1RU7) for each of its conformations generated from molecular dynamics simulation. For each conformation, we considered the set of residues involved in the union of these three interfaces. The dissimilarity between each pair of conformations was measured with our new methodology, the symmetric difference distance between the associated set of residues. The main advantages of the full procedure are: (i) it is parameter free; (ii) no spatial alignment is needed and (iii) it is simple enough so that it can be implemented by a beginner in programming. It is shown to be a relevant tool to follow the evolution of the conformation along the molecular dynamics trajectories.

scholarly journals High Temperature (30°C) Blocks Aerosol but Not Contact Transmission of Influenza Virus

2008 ◽  
Vol 82 (11) ◽  
pp. 5650-5652 ◽  
Author(s):  
Anice C. Lowen ◽  
John Steel ◽  
Samira Mubareka ◽  
Peter Palese
Keyword(s):  
Influenza Virus ◽  
Influenza Season ◽  
Virus Transmission ◽  
Tropical Regions ◽  
The World ◽  
Contact Transmission ◽  
Dry Conditions ◽  
Range Spread ◽  
Guinea Pig Model ◽  
The Tropics

ABSTRACT Influenza causes significant morbidity in tropical regions; however, unlike in temperate zones, influenza in the tropics is not strongly associated with a given season. We have recently shown that influenza virus transmission in the guinea pig model is most efficient under cold, dry conditions, which are rare in the tropics. Herein, we report the lack of aerosol transmission at 30°C and at all humidities tested. Conversely, transmission via the contact route was equally efficient at 30°C and 20°C. Our data imply that contact or short-range spread predominates in the tropics and offer an explanation for the lack of a well-defined, recurrent influenza season affecting tropical and subtropical regions of the world.

HIPEREMESIS GRAVIDARUM PADA IBU HAMIL DI KLINIK BIDAN SUPRIYATI SRIBIT BERBAH SLEMAN

2019 ◽  
Vol 14 (1) ◽  
pp. 51
Author(s):  
Pramukti Dian Setianingrum ◽  
Farah Irmania Tsani
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Hyperemesis Gravidarum ◽  
Unwanted Pregnancy ◽  
The Body ◽  
Nausea And Vomiting ◽  
Daily Activities ◽  
World Health ◽  
The World

Backgroud: The World Health Organization (WHO) explained that the number of Hyperemesis Gravidarum cases reached 12.5% of the total number of pregnancies in the world and the results of the Demographic Survey conducted in 2007, stated that 26% of women with live births experienced complications. The results of the observations conducted at the Midwife Supriyati Clinic found that pregnant women with hyperemesis gravidarum, with a comparison of 10 pregnant women who examined their contents there were about 4 pregnant women who complained of excessive nausea and vomiting. Objective: to determine the hyperemesis Gravidarum of pregnant mother in clinic. Methods: This study used Qualitative research methods by using a case study approach (Case Study.) Result: The description of excessive nausea of vomiting in women with Hipermemsis Gravidarum is continuous nausea and vomiting more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the body weight decreases and interferes with daily activities days The factors that influence the occurrence of Hyperemesis Gravidarum are Hormonal, Diet, Unwanted Pregnancy, and psychology, primigravida does not affect the occurrence of Hyperemesis Gravidarum. Conclusion: Mothers who experience Hyperemesis Gravidarum feel nausea vomiting continuously more than 10 times in one day, no appetite or vomiting when fed, the body feels weak, blood pressure decreases until the weight decreases and interferes with daily activities, it is because there are several factors, namely, hormonal actors, diet, unwanted pregnancy, and psychology.

New walls to keep the bad out: populism and the totalitarian psyche

2019 ◽  
Vol 1 (2) ◽  
pp. 120-130
Author(s):  
Coline Covington
Keyword(s):  
Cold War ◽  
Balance Of Power ◽  
Berlin Wall ◽  
Group Solidarity ◽  
Freedom Of Movement ◽  
Psychological Understanding ◽  
Psychic Development ◽  
The World ◽  
The Individual ◽  
The Cold War

The Berlin Wall came down on 9 November 1989 and marked the end of the Cold War. As old antagonisms thawed a new landscape emerged of unification and tolerance. Censorship was no longer the principal means of ensuring group solidarity. The crumbling bricks brought not only freedom of movement but freedom of thought. Now, nearly thirty years later, globalisation has created a new balance of power, disrupting borders and economies across the world. The groups that thought they were in power no longer have much of a say and are anxious about their future. As protest grows, we are beginning to see that the old antagonisms have not disappeared but are, in fact, resurfacing. This article will start by looking at the dissembling of a marriage in which the wall that had peacefully maintained coexistence disintegrates and leads to a psychic development that uncannily mirrors that of populism today. The individual vignette leads to a broader psychological understanding of the totalitarian dynamic that underlies populism and threatens once again to imprison us within its walls.

Virginia Woolf and Being-in-the-world

2017 ◽  
Author(s):  
Emma Simone
Keyword(s):  
Virginia Woolf ◽  
Historical Context ◽  
The Political ◽  
Cartesian Dualism ◽  
Self And Other ◽  
The World ◽  
Binary Oppositions ◽  
The Individual ◽  
The Relationship ◽  
Existential Perspective

Virginia Woolf and Being-in-the-world: A Heideggerian Study explores Woolf’s treatment of the relationship between self and world from a phenomenological-existential perspective. This study presents a timely and compelling interpretation of Virginia Woolf’s textual treatment of the relationship between self and world from the perspective of the philosophy of Martin Heidegger. Drawing on Woolf’s novels, essays, reviews, letters, diary entries, short stories, and memoirs, the book explores the political and the ontological, as the individual’s connection to the world comes to be defined by an involvement and engagement that is always already situated within a particular physical, societal, and historical context. Emma Simone argues that at the heart of what it means to be an individual making his or her way in the world, the perspectives of Woolf and Heidegger are founded upon certain shared concerns, including the sustained critique of Cartesian dualism, particularly the resultant binary oppositions of subject and object, and self and Other; the understanding that the individual is a temporal being; an emphasis upon intersubjective relations insofar as Being-in-the-world is defined by Being-with-Others; and a consistent emphasis upon average everydayness as both determinative and representative of the individual’s relationship to and with the world.

“Utopia First!” A Machiavellian Conception of Solidarity in More's Utopia

Moreana ◽  
2018 ◽  
Vol 55 (Number 209) (1) ◽  
pp. 79-93
Author(s):  
Marie-Claire Phélippeau
Keyword(s):  
At Risk ◽  
Human Beings ◽  
Farm Work ◽  
The World ◽  
Social Difficulties ◽  
The Republic ◽  
The Individual ◽  
Democratic Elections ◽  
Communal Organization

This paper shows how solidarity is one of the founding principles in Thomas More's Utopia (1516). In the fictional republic of Utopia described in Book II, solidarity has a political and a moral function. The principle is at the center of the communal organization of Utopian society, exemplified in a number of practices such as the sharing of farm work, the management of surplus crops, or the democratic elections of the governor and the priests. Not only does solidarity benefit the individual Utopian, but it is a prerequisite to ensure the prosperity of the island of Utopia and its moral preeminence over its neighboring countries. However, a limit to this principle is drawn when the republic of Utopia faces specific social difficulties, and also deals with the rest of the world. In order for the principle of solidarity to function perfectly, it is necessary to apply it exclusively within the island or the republic would be at risk. War is not out of the question then, and compassion does not apply to all human beings. This conception of solidarity, summed up as “Utopia first!,” could be dubbed a Machiavellian strategy, devised to ensure the durability of the republic. We will show how some of the recommendations of Realpolitik made by Machiavelli in The Prince (1532) correspond to the Utopian policy enforced to protect their commonwealth.

Drowning in negativism, self-hate, doubt, madness: Linguistic insights into Sylvia Plath’s experience of depression

2015 ◽  
Vol 11 (1) ◽  
pp. 41-54 ◽  
Author(s):  
Zsófia Demjén
Keyword(s):  
Lived Experience ◽  
Medical Humanities ◽  
Sylvia Plath ◽  
Individual Experience ◽  
Qualitative And Quantitative ◽  
The World ◽  
The Individual ◽  
Linguistic Methods ◽  
Linguistic Approach

This paper demonstrates how a range of linguistic methods can be harnessed in pursuit of a deeper understanding of the ‘lived experience’ of psychological disorders. It argues that such methods should be applied more in medical contexts, especially in medical humanities. Key extracts from The Unabridged Journals of Sylvia Plath are examined, as a case study of the experience of depression. Combinations of qualitative and quantitative linguistic methods, and inter- and intra-textual comparisons are used to consider distinctive patterns in the use of metaphor, personal pronouns and (the semantics of) verbs, as well as other relevant aspects of language. Qualitative techniques provide in-depth insights, while quantitative corpus methods make the analyses more robust and ensure the breadth necessary to gain insights into the individual experience. Depression emerges as a highly complex and sometimes potentially contradictory experience for Plath, involving both a sense of apathy and inner turmoil. It involves a sense of a split self, trapped in a state that one cannot overcome, and intense self-focus, a turning in on oneself and a view of the world that is both more negative and more polarized than the norm. It is argued that a linguistic approach is useful beyond this specific case.

The Attempt to Author the World: How Intellectualism Denies the Individual

2012 ◽  
Vol 8 ◽  
Author(s):  
Elizabeth R. Wheelock
Keyword(s):  
Marxist Theory ◽  
Personal Relationships ◽  
Simone De Beauvoir ◽  
Human Interactions ◽  
Second Sex ◽  
Existential Theory ◽  
Feminist Scholar ◽  
The World ◽  
The Individual ◽  
Existential Issues

Although primarily known as a feminist scholar and author of such works as She Came to Stay and The Second Sex, Simone de Beauvoir contributed heavily to French existential thought. The two writings upon which this paper focuses, The Ethics of Ambiguity and The Woman Destroyed, deal with the existential issues involved in human interactions and personal relationships. The Ethics of Ambiguity, famous as an exploration of the ethical code created by existential theory, begins with a criticism of Marxism and the ways in which it deviates from existentialism. Similarly, the first of the three short stories that make up de Beauvoir’s fictional work The Woman Destroyed follows the French intelligentsia and their similarities and digressions from Marxist and existential thought. In this paper, I seek to analyze Simone de Beauvoir’s criticism of Marxist theory in The Ethics of Ambiguity and its transformation into the critique of intellectualism found twenty years later in The Woman Destroyed. I will investigate Marxism’s alleged attempts to constrain the group it wishes to lead and the motivation behind these actions. Finally, I conclude with a discussion of the efficacy of fiction as a medium for de Beauvoir’s philosophy.

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