scholarly journals Changes in corneal thickness after vitrectomy—Implications for glaucoma practice

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249945
Author(s):  
Lisika Gawas ◽  
Aparna Rao
Keyword(s):  
Multivariate Regression ◽  
Corneal Thickness ◽  
Age Groups ◽  
Multivariate Regression Analysis ◽  
Age Group ◽  
Elevated Intraocular Pressure ◽  
History Of ◽  
Aphakic Eyes ◽  
The Difference ◽  
Contralateral Eye

Purpose To evaluate changes in central corneal thickness (CCT) following vitrectomy. Methods All consecutive old and new patients referred to glaucoma services for possible secondary glaucoma after vitrectomy and who had undergone corneal pachymetry between July 2013 to June 2020, were included. The eye that developed elevated intraocular pressure (IOP) and was diagnosed clinically as glaucoma after vitrectomy, was labelled as the “affected” eye. The contralateral eye of the patient with normal IOP and no history of vitrectomy was labelled as the “control” eye. The difference in CCT in the affected eye and the contralateral control eye (ΔCCT) and CCT were compared between different age groups. Correlation of CCT in the affected eye with age, diagnosis, type of surgery done, lens status and pre-existing glaucoma was done using multivariate regression analysis. Results Of 127 eyes of 120 patients (M:F = 85:35), the average CCT in the affected eye was significantly higher than the unaffected contralateral control eye (p<0.0001). The ΔCCT in eyes presenting at an age <25 years was higher (median 582, 497–840) than those that presented later (median 518, 384–755), p <0.0001, with maximum ΔCCT seen in eyes that had undergone vitrectomy at age<12 years. The CCT in the affected eye was significantly higher in aphakic eyes (588±81.6 microns) than in pseudophakic eyes (552±79.03 microns), p = 0.03. On multivariate analysis, age<25 years remained as a significant influencer of CCT in the affected eye (β = -1.7, p<0.001, R2 = 28.3%). Conclusions Young age group<25 years are more prone to corneal remodelling and CCT changes after vitrectomy.

scholarly journals PROMET: the effect of age on patient outcomes in non-laser transvenous lead extraction

EP Europace ◽  
2021 ◽  
Vol 23 (Supplement_3) ◽  
Author(s):  
Z Akhtar ◽  
A Elbatran ◽  
CT Starck ◽  
L WM Leung ◽  
M Sohal ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Multivariate Regression ◽  
Age Groups ◽  
Multivariate Regression Analysis ◽  
Lead Extraction ◽  
Similar Proportion ◽  
Age Group ◽  
Patient Age ◽  
Patient Âgé ◽  
Two Age Groups

Abstract Funding Acknowledgements Type of funding sources: None. OnBehalf PROMET group Background Cardiac implantable electronic devices (CIEDs) improve morbidity and mortality. This has fuelled an upsurge in implantation of these devices across all patient cohorts, simultaneously increasing the need for transvenous lead extractions (TLE). As the global population expands and life-expectancy extends, TLE will play a significant role in CIED management. Advancing patient age is a recognised risk factor for poor outcomes however the association between patient age and TLE outcomes remains unclear.  We sought to evaluate the relationship between patient age and non-laser TLE outcomes. Method Data of 2205 patients (3849 leads) was collected retrospectively from six high-volume TLE institutes across Europe (PROMET) between January 2005-December 2018. Propensity 1:1 score matching was performed to limit the effects of confounding variables, pairing 353 patients in the &gt;80 years of age category with 353 patients in &lt;80 years of age group. Procedural outcomes were compared between the two age groups and multivariate regression analysis was used for predictors of 30-day mortality. Results In the &lt;80 and &gt;80 years-of-age cohorts, there was a similar proportion of male patients (65.3% vs 67.9%, p = 0.47) treated under general anaesthesia (96.5% vs 93.4%, p = 0.078) for a pre-dominant infectious indication (56.7% vs 60.3%, p = 0.52) but with a higher requirement of the EvolutionTM sheath in the octogenarians (39.4% vs 48.4%, p = 0.015). A similar clinical success per lead was achieved between the two age groups (96.6% vs 98%, &lt;80 vs &gt;80 years, p = 0.245) as was complete lead extraction (95.5% vs 96.6%, &lt;80 vs &gt;80 years, p = 0.44) with a comparable minor complication rate (2.3% vs 3.1%, &lt;80 vs &gt;80 years, p = 0.29) and major complications (1.1% vs 1.4%, &lt;80 vs &gt;80 years, p = 0.74). Thirty-day mortality was higher in the octogenarian cohort than the &lt;80-year-olds without reaching statistical significance (5.4% vs 2.6%, p = 0.08); peri-procedural mortality was similar in both age groups (0.3% vs 0.6%, respectively, p = 0.56). Multivariate regression analysis revealed age (p = 0.013, OR 1.06 [1.01-1.12]), systemic infection (p = 0.026, OR 3.4 [1.16-10.35]) and lead dwell time (p = 0.007, OR 1.01 [1.003-1.017]) increased the odds of 30-day mortality. Conclusion Transvenous lead extraction is similar in efficacy and safety across all age groups. Thirty-day mortality is higher in the advanced age group, signifying the importance of post-procedural management in this cohort.

scholarly journals Tower Running—Participation, Performance Trends, and Sex Difference

2020 ◽  
Vol 17 (6) ◽  
pp. 1902 ◽  
Author(s):  
Daniel Stark ◽  
Stefania Di Gangi ◽  
Caio Victor Sousa ◽  
Pantelis Nikolaidis ◽  
Beat Knechtle
Keyword(s):  
Sex Differences ◽  
Statistical Model ◽  
Sex Difference ◽  
Random Effects ◽  
Age Groups ◽  
Repeated Measurements ◽  
Stair Climbing ◽  
Age Group ◽  
Performance Trends ◽  
The Difference

Though there are exhaustive data about participation, performance trends, and sex differences in performance in different running disciplines and races, no study has analyzed these trends in stair climbing and tower running. The aim of the present study was therefore to investigate these trends in tower running. The data, consisting of 28,203 observations from 24,007 climbers between 2014 and 2019, were analyzed. The effects of sex and age, together with the tower characteristics (i.e., stairs and floors), were examined through a multivariable statistical model with random effects on intercept, at climber’s level, accounting for repeated measurements. Men were faster than women in each age group (p < 0.001 for ages ≤69 years, p = 0.003 for ages > 69 years), and the difference in performance stayed around 0.20 km/h, with a minimum of 0.17 at the oldest age. However, women were able to outperform men in specific situations: (i) in smaller buildings (<600 stairs), for ages between 30 and 59 years and >69 years; (ii) in higher buildings (>2200 stairs), for age groups <20 years and 60–69 years; and (iii) in buildings with 1600–2200 stairs, for ages >69 years. In summary, men were faster than women in this specific running discipline; however, women were able to outperform men in very specific situations (i.e., specific age groups and specific numbers of stairs).

scholarly journals Age and sex variation in visceral adipose tissue

2019 ◽  
Vol 6 (1) ◽  
pp. 101
Author(s):  
Pallavi Panchu ◽  
Biju Bahuleyan ◽  
Rose Babu ◽  
Vineetha Vijayan
Keyword(s):  
Adipose Tissue ◽  
Visceral Fat ◽  
Metabolic Disorders ◽  
Age Groups ◽  
Fat Distribution ◽  
Age Group ◽  
Cross Sectional ◽  
Younger Age ◽  
The Difference ◽  
Gender Pattern

Background: Adipose tissue mainly visceral fat is said to be harmful and acts as a harbinger of metabolic disorders. A changing trend is seen in the recent decades with decreasing incidence of metabolic disorders in men even though visceral fat is said to be higher in them. Sex hormones may influence the deposition pattern of adipose tissue. The aim of this study was to observe effects of age on visceral fat and to know if the difference in gender pattern of fat distribution is maintained throughout life or disappears after menopause.Methods: This cross-sectional observational study was conducted in Thrissur on 385 apparently healthy subjects using Omron body composition analyser. Data was analysed using SPSS 20.0 version. The tests employed were NOVA, independent samples t-test.Results: In each age group, men had significantly higher visceral fat than females. As age increased, visceral fat increased significantly in both genders. In each group, except for younger age groups, VF levels were equal in men and women.Conclusions: Visceral fat is higher in men and this difference is seen in all age groups. As age increases, visceral fat levels also increased in men and women. The distribution of visceral fat is such that a greater number of men have high to very high levels at a younger age group, a feature observed in women only in the peri and post-menopausal age. Adoption of an active lifestyle coupled with healthy diet should protect against onset of metabolic disorders.

scholarly journals Prevalence and risk factors of pulmonary nontuberculous mycobacterial infections in the Zhejiang Province of China

2019 ◽  
Vol 147 ◽  
Author(s):  
Jintian Xu ◽  
Ping Li ◽  
Shengchao Zheng ◽  
Wei Shu ◽  
Yu Pang
Keyword(s):  
Risk Factors ◽  
Reference Group ◽  
The Elderly ◽  
Zhejiang Province ◽  
Age Group ◽  
Pulmonary Tb ◽  
History Of ◽  
Normal University ◽  
The Difference ◽  
Culture Positive

Abstract Risk factors and prevalence of pulmonary nontuberculous mycobacterial (NTM) diseases were retrospectively evaluated in 1208 suspected pulmonary TB patients seeking care at the Affiliated Hospital of Hangzhou Normal University between July 2018 and December 2018. Further analysis of 390 culture-positive cases demonstrated that 358 (358/390, 91.8%) were infected with Mycobacterium tuberculosis (MTB), 24 (24/390, 6.2%) with NTM and eight (8/390, 2.0%) with both MTB and NTM. M. intracellulare was the most prevalent NTM isolated (16/24, 66.7%), followed by M. abscessus (3/24), M. kansasii (2/24), M. avium (1/24), M. szulgai (1/24) and M. fortuitum (1/24). The difference between NTM and TB case rates for the ⩾65-year-old age group significantly exceeded the difference for the reference group (patients aged 25–44 years) (OR (95% CI): 4.63 (1.03–20.90)). Pulmonary NTM diseases incidence positively correlated with prior TB history (OR (95% CI): 12.92 (3.24–31.82)). Moreover, pulmonary NTM patients were significantly more likely to exhibit underlying bronchiectasis than pulmonary TB patients (OR (95% CI): 18.89 (7.54–47.88)). In conclusion, approximately one-tenth of culture-positive suspected pulmonary TB patients are infected with NTM (most frequently M. intracellulare) in Zhejiang Province, China. The elderly and those with bronchiectasis or a history of TB are at the greatest risk of contracting pulmonary NTM disease.

FC13-04 - Suicide risk in relation to age and psychiatric hospitalization

2011 ◽  
Vol 26 (S2) ◽  
pp. 1885-1885
Author(s):  
J. Reutfors ◽  
L. Brandt ◽  
K. Sparring Björkstén ◽  
A. Ekbom ◽  
U. Ösby
Keyword(s):  
Suicide Risk ◽  
Psychiatric Hospitalization ◽  
Conditional Logistic Regression ◽  
Age Groups ◽  
The Elderly ◽  
Population Based ◽  
Age Group ◽  
Post Discharge ◽  
History Of ◽  
Control Study

IntroductionSuicide risk is increased in patients with a history of psychiatric hospitalization.AimTo explore how suicide risk varies by age during psychiatric hospitalization and in the year post-discharge.MethodsThis is a population-based case-control study of all suicides (n = 20,675; 70% male) in Sweden aged ≥18 years during 1991–2003. Each suicide was individually matched to 10 population controls by age, sex, and county of residence. Discharge diagnoses of a mental disorder (except dementia and other organic disorders) in the year prior to suicide were identified by register linkage. Odds ratios (OR) were calculated by conditional logistic regression to estimate the relative risk of suicide in those with psychiatric diagnoses compared to the general population. ORs were estimated by age group (18–34 years, 35–49 years, 50–64 years, and ≥ 65 years) and timing of the suicide in relation to discharge.ResultsDuring hospitalization, the youngest age group had the greatest suicide risk elevation [OR 64 (95% CI 44-92)]. In the first month post-discharge, the oldest age group had the highest suicide risk elevation [OR 162 (95% 66–399) in the first week and OR 127 (95% 67–242) in the second to fourth weeks]. In the remaining eleven months, suicide risk elevation was lower and relatively similar in different age groups.ConclusionsDuring the year following psychiatric hospitalization, an especially high attention should be paid to the suicide risk of the elderly patients in the first month post-discharge.

Evaluation of intra-uterine contraception in selected mission hospitals in India

1973 ◽  
Vol 5 (3) ◽  
pp. 377-391 ◽  
Author(s):  
K. Sadashivaiah ◽  
M. S. Subba Rao
Keyword(s):  
Post Partum ◽  
Age Groups ◽  
Fertility Control ◽  
Control Programme ◽  
Age Group ◽  
Follow Up Study ◽  
The Difference ◽  
Living Children ◽  
Two Age Groups

SummaryIntra-uterine contraception is a useful method of fertility control, because of its applicability at all levels of socio-economic development and it has been the mainstay of the fertility control programme in many countries.The present evaluation is based on the hospital follow-up records of 4067 IUD cases from randomly selected mission hospitals for the years 1967 and 1968. Of the insertions, 97·7% were non-post-partum, and 60% of the acceptors were from the age group 25–34 years with a median age of 29·8 years; nearly 70% had fewer than four living children. The pattern of distribution by religion is similar to that of the 1961 census figures.The average number of women months (6·7) of IUD use is very low in a follow-up study of 24 months but is more or less consistent, both by age and parity.The incidence of expulsion, removal and pregnancy was 8·2, 12·9 and 0·6 respectively for all ages and although these rates were higher with the 27½-mm loop than the 30-mm loop the differences are not statistically significant.The rates of expulsion, removals and complaints were greatest during the first 6 months of use and decreased gradually with increase in duration of use.Bleeding, or other symptoms associated with bleeding, were the main reasons for the removals.Incidence of re-insertion was higher among those aged <25 years than among those aged ≥25 years and the difference in the proportion of re-insertions between the two age groups is statistically significant.The size of the loop seems to have no bearing on the incidence of re-insertions.Total termination rates at the end of 6, 12, 18 and 24 months were 9·9, 15·2, 25·0 and 55·9 per 100 first insertions respectively.

scholarly journals Contestation of Perspectives Toward Suicide in The Film Monsieur Lazhar (2011) by Philippe Falardeau

2021 ◽  
Vol 5 (1) ◽  
pp. 1
Author(s):  
Tesya Imanisa Setiadi ◽  
Wening Udasmoro ◽  
Hayatul Cholsy
Keyword(s):  
Causes Of Death ◽  
Age Groups ◽  
Young Age ◽  
Age Group ◽  
Adult Age ◽  
Personal Experiences ◽  
The Difference ◽  
Relationship Of ◽  
The Relationship ◽  
Keywords Suicide

Abstract. Suicide is one of the causes of death that occurs in a global scope but always causes divisive perspectives in various circles of society. For most people, suicide is a taboo topic, but not for other groups. The film Monsieur Lazhar (2011) is a film that shows the different perspectives between different age groups, namely the adult age group and the young age group, on a suicide that occurred at an elementary school in Montreal, Canada. This study aims at determining the different perspectives of the two different parties on suicide and the reasons for these differences in views. Pierre Bourdieu’s Champ de Force theory is the lens used in this research. The difference in perspective is influenced by the disposition system which Bourdieu calls the habitus. Habitus operates in a realm (champ). In the film, the domain in question is school. Meanwhile, Durkheim’s theory of suicide was chosen to determine the relationship of social problems to suicide. The method used in this research is content analysis. The data used are the chronological text of the scenes and the transcript of the conversations from the film. From the research, it was found that the school, which is the adult age group, has a counter and stigmatic view of suicide, reinforced by perceptions of psychological problems and social taboos. Meanwhile, students, who are in the young age group, tend to view suicide as a problem related to personal aspects and personal experiences so that they do not have a judgmental attitude like the school. Keywords : Suicide, Contestation, Realm, Perspective, Habitus

scholarly journals The Comparison of Accelerated Corneal Crosslinking Treatment for Progressive Keratoconus in the Pediatric and Adult Age Groups: One-Year Results

2021 ◽  
Author(s):  
Mustafa Berhuni ◽  
Cem Ozturkmen
Keyword(s):  
Visual Acuity ◽  
Corneal Thickness ◽  
Age Groups ◽  
Age Group ◽  
Preoperative Period ◽  
Adult Group ◽  
Adult Age ◽  
Pediatric Age Group ◽  
Significant Difference ◽  
One Year

Abstract Purpose: To investigate the short-term results of accelerated crosslinking (A-CXL) treatment for progressive keratoconus in the pediatric and adult age groups. Materials and methods: The records of the 62 eyes of 40 patients who had undergone the A-CXL procedure (9 mV/cm2, 10 min) for progressive keratoconus between January 2015 and January 2019 were evaluated retrospectively. The patients were divided into 2 groups as the pediatric group (aged 17 years or less) and the adult group (aged 18 years or more) for statistical analysis. Pre- and post- 12th month A-CXL best-corrected visual acuity (BCVA), maximum keratometry (Kmax), sim K1, sim K2, corneal thickness at the thinnest point (thCT), and corneal astigmatism (CA) values of the patient groups were recorded. Results: The 29 eyes of 16 patients were included in the pediatric group and the 33 eyes of 24 patients were included in the adult group. The mean age was 13.50±3.05 years in the pediatric group and 23.58±4.37 years in the adult group. A significant improvement in BCVA and a significant decrease in thCT values were present in both groups 12 months after the surgery compared to the preoperative period. A decrease was present in the Kmax, sim K1, sim K2 and CA values in the pediatric group, but was not statistically significant. The decrease in Kmax, sim K1 and sim K2 values compared to the preoperative period was significant in the adult group, but the decrease in CA values was not significant. When the two groups were compared at the end of 12 months, only the sim K1 value was significantly lower in the adult group, and there was no significant difference between the other measurements. Conclusions: Better visual acuity improvement, a higher flattening rate, and less progression occur after 12 months with A-CXL treatment for progressive keratoconus in the adult age group compared to the pediatric age group.

scholarly journals Width of 3. Ventricle: Reference Values and Clinical Relevance in a Cohort of Patients with Relapsing Remitting Multiple Sclerosis

2013 ◽  
Vol 7 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Martin Müller ◽  
Regina Esser ◽  
Katarina Kötter ◽  
Jan Voss ◽  
Achim Müller ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Regression Analysis ◽  
Brain Atrophy ◽  
Multivariate Regression ◽  
Multivariate Regression Analysis ◽  
Age Group ◽  
Relapsing Remitting ◽  
Clinical Conditions ◽  
Relapsing Remitting Multiple Sclerosis ◽  
Age Range

Objectives: To estimate the quantity of multiple sclerosis (MS) patients with brain atrophy as indicated by third ventricular enlargement using transcranial colourcoded ultrasound (TCCS). Methods: The width of the 3. ventricle was assessed by TCCS in 70 healthy controls (male 31, female 39, mean age 41 ± 15 years, age range 18 – 79 years), and in a cohort of 54 patients with relapsing remitting MS (male 16, female 38, mean age 40 ± 10 years, median EDSS 2 [1-3]). Results: In the controls, the width of the 3. ventricle increased with age (without any sex differences) from 3.0 ± 0.76 mm in the age group < 40 years to 4.0 ± 0.74 mm in the age group of 60 years or more (ANOVA p=0.0001). Derived from regression analysis, the upper limit of the 95% Confidence Interval for each year provided cutoff points according to which 14 of 54 patients (25%) exhibited an enlarged 3. ventricle. In a multivariate regression analysis, the width of the 3. ventricle over all MS patients was significantly related to EDSS (Spearman rho , r=0.446, p<0.005) and to MS duration (r=0.319, p<0.005). Conclusions: Even in MS patients in good clinical conditions the rate of patients with brain atrophy determined by TCCS is high.

scholarly journals Histological study of proportion of cortex and medulla of the ovary in Bangladeshi women

2016 ◽  
Vol 44 (1) ◽  
pp. 8-10
Author(s):  
Hosna Ara Perven ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Dilruba Siddiqua ◽  
Fatema Johora ◽  
Halima Afroz ◽  
...  
Keyword(s):  
Histological Study ◽  
Age Groups ◽  
Age Group ◽  
Cross Sectional ◽  
Medical College ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Group B ◽  
The Right

This cross sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka from January to December 2009, to determine the proportion of cortex and medulla of the ovary in di_erent age group of Bangladeshi women. This study was based on collection of 140 ovaries of 70 unclaimed female dead bodies from the morgue of Dhaka Medical College, Dhaka. The samples were divided into three age-groups including A (10-13 years), B (14-45 years) & C (46-52 years). Histological slides were prepared by using routine haematoxylin and eosin stain. Ten best prepared histological slides from each age group were examined to determine the thickness of the cortex and medulla & proportion of the thickness of the cortex and the medulla of the ovary were expressed in percentages. The mean proportion of the cortex and the medulla of the right ovary were found 80.83±0.58% and 19.17±0.58% in group A, 86.95±1.14% and 13.05±1.14% in group B, 70.53±1.53% and 29.47±1.53% in group C respectively. The mean proportion of the cortex and the medulla of the left ovary were found 80.63±0.58% and 19.37±0.58% in group A, 86.78±1.14% and 13.22±1.14% in group B, 70.41±1.50% and 29.59±1.50% in group C respectively. The difference in mean proportion of the cortex and the medulla was not signi_cant in between the ovaries. However, the difference in mean proportion of the cortex and the medulla of the ovary between group A & group B, group A & group C and group B & group C were statistically significant.Bangladesh Med J. 2015 Jan; 44 (1): 8-10

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