scholarly journals Estimating the gains of early detection of hypertension over the marginal patient

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254260
Author(s):  
Paul Rodríguez-Lesmes

This study estimated the potential impact of early diagnosis programs on health outcomes in England. Specifically, if advising individuals to visit their family doctor due to a suspected case of mild hypertension would result in (i) an increase in the diagnosis and treatment of high blood pressure; (ii) an improved lifestyle reflected in objective measures such as the body-mass-index and blood pressure levels; (iii) a reduced probability of the onset of other cardiovascular diseases, such as diabetes. To address potential selection bias in screening, a feature of the English Longitudinal Study of Ageing is exploited, motivating a regression discontinuity design. If respondents’ blood pressure measurements are above a standard clinical threshold, they are advised to visit their family doctor to confirm hypertension. Two years after the protocol, there is evidence of an increase in diagnosis (5.7 pp, p-val = 0.06) and medication use (6 pp, p-val = 0.007) for treating the condition. However, four years after the protocol, the difference in diagnosis and medication disappeared (4 pp, p-val = 0.384; 3.4 pp, p-val = 0.261). Moreover, there are no differences on observed blood pressure levels (systolic 0.026 mmHg, p-val = 0.815; diastolic -0.336 mmHg, p-val = 0.765), or Body-Mass-Index ((0.771, p-val = 0.154)). There are also no differences on diagnosis of diabetes (1.7 pp, p-val = 0.343) or heart related conditions (3.6 pp, p-value = 0.161). In conclusion, the nudge produces an earlier diagnosis of around two years, but there are no perceivable gains in health outcomes after four years.

2015 ◽  
Vol 1 (1) ◽  
pp. 44
Author(s):  
Budi Somantri

Background. Aging is a natural process after the three stages of life, namely children, adulthood and old age that cannot be avoided by any individual. The increase of the age will cause changes in the structure and physiological properties of a range of cells, organs and systems in the body. Metabolic processes that decrease on the elderly will lead to obesity due to decreased physical activity, then the excess calories will be converted into fat resulting in obesity. Overweight or obesity is one of the factors that can influence blood pressure and the development of hypertension. Purpose. The purpose of this research was to know the correlation between Body Mass Index with elderly blood pressure in puskesmas Melong Asih Cimahi. Methods. The methods in this study used analytic research method with cross sectional approach, there were 80 elderly (60- 74 years) as respondents. Sampling techniques used simple random sampling. Results. The results of univariat analysis used frequency distribution showed distribution evenly on IMT skinny (20%), normal (26.2%), fat (26.2%), obesity (27.6%). Similarly, on the frequency distribution of blood pressure normal (36.2%), pre hypertension (31.2%), and hypertension (32.6%). The results of Chi-Square statistical test showed p value = 0.000 < a 0.05. Conclusions. The conclusions from this study which conducted on June 2013 that there was a correlation between Body Mass Index (BMI) with elderly blood pressure in Puskesmas Melong Asih Cimahi.


Elements ◽  
2018 ◽  
Vol 14 (1) ◽  
Author(s):  
Sara Samir

Studies of stress and cortisol levels in adults indicate that keeping normal levels of cortisol is beneficial to subjects. The hormone cortisol has many functions including proper glucose metabolism, regulation of blood pressure, immune function, and inflammatory  response. When cortisol levels spike, as with stress, there can be a negative effect on the individual. Due to the hectic pace of modern life, the body’s stress response does not always have time to return to normal, leading to cortisol levels remaining too high. This can lead to suppressed thyroid function, blood sugar imbalances, higher blood pressure, lowered immunity, and increased abdominal fat. Stress plays a prominent role in the lives of millions of people all across the globe. This problem is not one that affects solely the adult population but also a multitude of adolescents and children. Oftentimes, stress can have both a physical and psychological effect on an individual. Many persons report an effect on food consumption when under stressful situations, causing one to either eat more or less than normal. In turn, these eating patterns can potentially influence the Body Mass Index (BMI) of an individual. While increased stress can lead to a higher or lower than normal cortisol level and BMI in adults, the role in adolescents is not entirely clear. This study investigated whether there is a relationship between stress and BMI in high-achieving adolescents, aged 14 to 18. The Perceived Stress Scale survey paired with additional questions that helped determine variables believed to impact stress levels were administered to determine overall stress levels in each subject. To determine cortisol levels, a competitive enzyme immunoassay was used.  This study indicates that there   are no significant correlations between perceived stress levels, salivary cortisol levels, and BMI in this group of individuals. However, a distinct difference in self-assessed stress levels was apparent between males and females. Somewhat unexpectedly, a negative relationship was found between BMI and salivary cortisol levels and perceived stress and salivary cortisol levels.


Author(s):  
S Bhosale Komal ◽  
V Bhosale Siddhi ◽  
Anandh Dr. S

Women in postmenopausal period of their life face various physical and physiological changes causing lack of estrogen and progesterone hormones, changes in the reproductive and genitals organs, vasomotor system in the body along with mood related symptoms such as anxiety, etc. Lifestyle, body fat distribution and anthropometric changes adds on to the bone strength in postmenopausal women. It may be a risk factor for osteoporotic fracture, cardiovascular, metabolic diseases, etc. Core strength and stability is greatly influenced by body composition and adiposity. The aim of the study was to correlate the core strength assessed with the Body Mass Index (BMI) among postmenopausal women. The objective of the study is to find the correlation between the core strength assessed with the Body Mass Index using 60° flexion test, Beiring Sorenson test and Unilateral Hip Bridge Endurance test among postmenopausal women with age ranging from 46-70 years. 96 healthy postmenopausal women in Karad city with a natural history of menopause were selected for the study. Based upon BMI values, the subjects were grouped as Underweight (<18.5 kg/m2), Normal weight (18.5-24.9 kg/m2), Overweight (25-29.9 kg/m2 and more). The outcome values for strength were correlated with the BMI of postmenopausal women. In the study, the Pearson correlation(r) was -0.361 and the P value was 0.0003 showing extremely significant correlation between the BMI and 60° Flexion test. For the Beiring Sorenson Test, the Pearson correlation value was -0.305 and the P value was 0.0025 showing very significant correlation between the BMI and Beiring Sorenson Test. Correlation of BMI and Unilateral Hip Bridge Endurance Test shows a Pearson Correlation value of -0.322 and the P value 0.0013 claiming very significant correlation between the BMI and Unilateral Hip Bridge Endurance Test. The study concludes that there is a significantly negative correlation between the core strength and stability with the Body Mass Index among postmenopausal women.


2021 ◽  
Vol 34 ◽  
Author(s):  
Miguel Angelo dos Santos DUARTE JUNIOR ◽  
Adroaldo Cezar Araujo GAYA ◽  
Vanilson Batista LEMES ◽  
Camila Felin FOCHESATTO ◽  
Caroline BRAND ◽  
...  

ABSTRACT Objective To verify the multivariate relationships between eating habits, cardiorespiratory fitness, body mass index, and cardiometabolic risk factors in children. Methods This is a cross-sectional study developed in a public elementary school with 60 first- to sixth-graders. Their eating habits were assessed using the Food Frequency Survey, weight, height, and cardiorespiratory fitness, assessed according to the Projeto Esporte Brasil protocol. Moreover, the variables, high-density lipoprotein, low-density lipoprotein, glucose, insulin, C-reactive protein, adiponectin, leptin, diastolic and systolic blood pressure were evaluated. Descriptive statistics were used for data analysis and generalized estimation equations were used for the analysis of direct and indirect relations, in a multivariate analysis model with several simultaneous outcomes. Results It appears that the eating habits and cardiorespiratory fitness explain 20% of the body mass index. Cardiometabolic risk factors are explained by the relationship between eating habits, cardiorespiratory fitness, and body mass index, according to the following percentages: 29% (systolic blood pressure), 18% (diastolic blood pressure), 63% (leptin), 4% (adiponectin), 14% (C-reactive protein), 17% (insulin), 10% (high-density lipoprotein), 1% (low-density lipoprotein), 4% (glucose). It is also observed that the effects of the eating habits on cardiometabolic risk factors are indirect, that is, they are dependent on changes in the body mass index and cardiorespiratory fitness levels. Conclusions The relationship between eating habits and cardiometabolic risk factors in children is dependent on cardiorespiratory fitness and body mass index. Thus, our findings suggest a multivariate relationship between these factors.


2007 ◽  
Vol 135 (7-8) ◽  
pp. 440-446 ◽  
Author(s):  
Biljana Beleslin ◽  
Jasmina Ciric ◽  
Milos Zarkovic ◽  
Zorana Penezic ◽  
Svetlana Vujovic ◽  
...  

Introduction Obesity is often accompanied by a number of complications including diabetes mellitus and cardiovascular diseases. Elevated blood pressure and lipids, as well as deterioration of glucoregulation are attributed, as the most significant factors, to development of diabetes mellitus and cardiovascular complications in obese patients. Objective The aim of our study was to evaluate the effects of a fasting diet on blood pressure, lipid profile and glucoregulatory parameters. Method We included 110 patients (33 male and 77 female; mean age 35?1 years, body weight 131.7?2.6 kg, body mass index 45.4?0.8 kg/m2) who were hospitalized for three weeks for the treatment of extreme obesity with the fasting diet. At the beginning, during, and at the end of this period, we evaluated changes in blood pressure, lipid profile, as well as parameters of glucoregulation including glycaemia, insulinaemia, and insulin sensitivity by HOMA. Oral glucose tolerance test (OGTT) was performed in all patients at the beginning and at the end of the fasting diet. Results During the fasting diet, the body weight decreased from 131.7?2.6 kg to 117.7?2.4 kg (p<0.001), the body mass index decreased from 45.4?0.8 kg/m2 to 40.8?0.8 kg/m2 (p<0.001), and both systolic and diastolic blood pressure significantly declined (143?2 vs. 132?2 mm Hg, p<0.001; 92?2 vs. 85?2 mm Hg, p<0.001). In addition, the fasting diet produced a significant decrease in total cholesterol, LDL cholesterol, triglycerides, as well as basal glycaemia and insulinaemia (p<0.001) Before the fasting diet, OGTT was normal in 76% of patients, whereas 21% of patients showed glucose intolerance, and 4% of patients diabetes mellitus. After the fasting diet, OGTT was normal in 88% of patients, whereas 12% of patients still had signs of glucose intolerance (p<0.05). In addition, insulin resistance significantly (p<0.05) increased from 54?6% to 89?13% after the fasting diet. Conclusion The three-week fasting diet in extremely obese patients produced a significant decrease and normalization of blood pressure, decrease in lipids, and improvement in glucoregulation including the increase in insulin sensitivity.


2021 ◽  
Vol 6 (2) ◽  
pp. 1436-1439
Author(s):  
Henry Afamuefuna Efobi ◽  
Iya Eze Bassey

Introduction: Hypertension is a long-term medical condition which when not detected and managed properly and on time often results to complications leading to disabilities and mortality. Gender has been known to affect the interpretation of some variables necessitating the need for gender-specific ranges. Objectives:This study evaluated total creatine kinase (CK) and creatine kinase-MB (CK-MB) isoenzyme activities of hypertensive subjects in Calabar, Nigeria and to assess if gender has influence on the activities of these enzymes. Methodology:One hundred and two participants were consecutively enrolled in this case control study. Serum total serum CK and CK-MB activity were evaluated in fifty one hypertensive and 51 normotensive subjects. The total CK levels were assessed using a spectrophotometric method while immunoinhibition method was used to determine the activity of CK-MB. Data was analyzed using Student’s t-test and Pearson’s correlation. Statistical significance was set at p<0.05. Results:The total creatine kinase activities of the hypertensives did not differ significantly from those of the normotensive controls (p = 0.428) while the serum CK-MB activities of the hypertensive subjects were significantly higher than those of the normotensive controls (p=0.000). The body mass index of the hypertensives was significantly higher than those of the normotensive subjects (p=0.030). Gender had no effect on the blood pressure, body mass index and levels of CK and CK-MB (p>0.05). There was also no significant correlation (p>0.05) between blood pressure, body mass index and the levels of CK and CK-MB. Conclusion:CK-MB activities were significantly higher in hypertensive subjects compared to normotensive controls. There were no gender specific differences in the CK-MB levels of male and female hypertensives. This cardiac marker should be included in the routine assessment of hypertensives and gender-specific considerations may not be necessary in the interpretation of the data.


2021 ◽  
Vol 1 (2) ◽  
pp. 52-58
Author(s):  
Devi ◽  
Bambang S ◽  
Sumedi W

Introduction: Dietary factors or eating patterns can cause patients to experience anorexia so that it affects the body mass index measured by CKD patients (Susetyowati, 2014). Therefore, it is important to understand the research when studying the relationship between the diet of CKD patients and the body mass index of patients undergoing hemodialysis at the Dik Pusdikkes Hospital in 2021. Objective: This study aims to determine how big the influence of the relationship between the diet of CKD patients and the body mass index of patients undergoing hemodialysis to improve the quality of life of CKD patients. Method: The type of research used is quantitative research with a correlational design to determine whether there is a relationship between variables using experimental research. The population in this study that became the study population were all hemodialysis patients at the AD Pusdikkes Hospital. The sampling technique used was total sampling. The research instrument used is a questionnaire. The questionnaire is not standardized so that validity and reliability tests are carried out. In this study, the analysis used the chi-square test. Results: the results of the chi-square test showed that the p-value (0.028) <0.05 then Ha was accepted or there was a relationship between the diet of CKD patients and the patient's body mass index. Conclusion: Based on the results of the analysis of the relationship between the evaluation of hemodialysis patients at RS Dik Pusdikkes Kodiklat AD, 9 respondents had a poor diet with a body mass index in the lean category of 6 people (66.7%) and the normal category of 3 people (33.3%). And 11 respondents have a good diet relationship with body mass index in the thin category of 2 people (40.0%) and the normal category of 12 people (60%).


2021 ◽  
Vol 1 (1) ◽  
pp. 103-114
Author(s):  
Rilyani Rilyani ◽  
Lidya Aryanti ◽  
Calvyn Reza Trisnantyas

ABSTRACT: EMPLOYMENT RELATIONSHIP AND WORKING SCHEDULE WITH BODY MASS INDEX IN YOSODADI PUSKESMAS WORKING AREA METRO CITY Introduction: The coverage of children under five in Lampung Province in 2019 was 79%, and this figure was above the target (76.18%). This figure illustrates that participation from the community to come to posyandu is still quite good in Lampung Province, while for Metro City the percentage of data is weighted at 78.8%. Data obtained through the Metro City Health Office in 2020 at the Yosodadi Health Center obtained as many as 656 toddlers aged 1-5 years who were weighingObjective: To find out the relationship between work and work schedule with the body mass index of toddlers aged 1-5 years.Methods: This type of research is quantitative. The design in this study uses an analytical survey design with a cross-sectional approach. The population is mothers and children aged 3-5 years, which is then calculated using the Slovin formula to obtain 197 children. Sampling technique purposive sampling Analysis of univariate and bivariate data using the chi-square test.Results: working mothers as many as 107 respondents (54.3%)., standard work schedule is 8 hours per day as many as 109 respondents (55.3%), BMI is not ideal, namely < 18.5 and > 22.9 as many as 103 respondents ( 52.3%. The results of statistical tests using the chi-square test obtained p-value = 0.000 (<α0.05), p-value = 0.085 (>α0.05).Conclusion: The results of statistical tests using the chi-square test obtained p-value = 0.000 (<α0.05) which means the relationship between mother's work and body mass index of toddlers aged 3-5. The p-value = 0.085 (>α0.05) means that there is no relationship between the mother's work schedule and the body mass index of children aged 3-5 years. It is recommended that parents who have toddlers with underweight and obese nutritional status should pay more attention to parenting patterns Keywords            :  Mother's Work Work Schedule, Toddler Body Mass Index  INTISARI: HUBUNGAN PEKERJAAN DAN JADWAL KERJA DENGAN INDEKS MASSA TUBUH BALITA DI WILAYAH KERJA PUSKESMAS YOSODADI KOTA METRO   Pendahuluan: Cakupan balita ditimbang di Provinsi lampung tahun 2019 sebesar 79 %, dimana angka ini diatas target (76,18%). Angka ini menggambarkan bahwa partisipasi dari masyarakat untuk datang ke posyandu masih cukup baik di Provinsi Lampung, sedangkan untuk Kota Metro persentase data ditimbang sebesar 78,8%. Data yang diperoleh melalui Dinkes Kota Metro tahun 2020 di Puskesmas Yosodadi didapat sebanyak 656 balita usia 1-5 tahun yang melakukan penimbangan berat badanTujuan: Diketahui hubungan pekerjaan dan jadwal kerja dengan  indeks massa tubuh balita usia 1-5 tahun.Metode: Jenis penelitian kuantitatif, Rancangan dalam penelitian ini menggunakan desain Survei Analitik dengan pendekatan cross sectional. Populasi adalah  ibu dan anak usia 3-5 tahun, yang kemudian dilakukan perhitungan sampel dengan rumus slovin didapat sebanyak 197 anak. Teknik sampling purposive sampling Analisa data univariat dan bivariat  menggunakan uji chi square.Hasil : ibu bekerja sebanyak 107 responden (54,3%)., jadwal kerja standar yaitu 8 jam per hari sebanyak 109 responden (55,3%), IMT tidak ideal yaitu < 18,5 dan > 22,9 sebanyak 103 responden (52,3%). Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0.000 (<α0.05), nilai p-value = 0.085 (>α0.05).Kesimpulan : Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0.000 (<α0.05) yang artinya ada hubungan pekerjaan ibu dengan  indeks massa tubuh balita usia 3-5. Nilai p-value = 0.085 (>α0.05) yang artinya tidak ada hubungan jadwal kerja ibu dengan  indeks massa tubuh balita usia 3-5 tahun. Disarankan kepada orang tua yang memiliki balita dengan status gizi kurus dan gemuk, harus lebih memperhatikan lagi mengenai pola asuh anak           Kata Kunci      : Pekerjaan Ibu Jadwal Kerja, Indeks Masa Tubuh Balita 


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