scholarly journals A Non aqueous Formulation for Efficient Detoxification of Chemical Weapons at Sub zero Temperatures

2020 ◽  
Vol 5 (1) ◽  
pp. 10-17
Author(s):  
G.K. Prasad ◽  
Lokesh K. Pandey ◽  
Virendra V. Singh ◽  
K. Ganesan ◽  
Jyotiranjan Acharya ◽  
...  
Keyword(s):  
Potassium Hydroxide ◽  
Sulfur Mustard ◽  
Field Application ◽  
Environmentally Benign ◽  
Chemical Weapons ◽  
Ambient Conditions ◽  
Vinyl Sulfide ◽  
Wide Range ◽  
New Formulation ◽  
Near Future

An effective decontamination methodology based on nucleophilic non-aqueous decontaminant has been developed against chemical weapons sulfur mustard and soman. This new formulation consists of non-aqueous solution of 2-aminoethanol (60%, w/v), potassium hydroxide (2%, w/v), and N-methyl-2-pyrrolidone (38 %, w/v) and detoxified more than 99 % of sulfur mustard and soman within a period of 30 min at -35 °C. It was found to be operable over a wide range of temperatures starting from -35 °C to +55 °C without losing its fluidity and detoxicant efficiency at sub-zero temperatures promising hassle-free application against chemical weapons. It degrades sulfur mustard to divinyl sulfide and 2-chloroethyl vinyl sulfide and converted soman into O-pinacolyl O’-(2-amino) ethyl methylphosphonate, which are relatively non toxic to humans. This formulation is environmentally benign, relatively non corrosive and has an improved capability to dissolve and decontaminate chemical weapons within 15 minutes at ambient conditions. This approach paves the way for efficient and rapid decontamination platform for chemical weapons and holds considerable promise for field application in near future.

The chemistry of 4-(dicyanomethylene)-3-methyl-l-phenyl-2-pyrazoline-5- ones as a privileged scaffold in synthesis of heterocycles

2020 ◽  
Vol 17 ◽  
Author(s):  
Mohsen A.-M. Gomaa ◽  
Huda A. Ali
Keyword(s):  
Building Block ◽  
Heterocyclic Compounds ◽  
Recent Progress ◽  
Reaction Conditions ◽  
Azacrown Ethers ◽  
Wide Range ◽  
Privileged Scaffold ◽  
Number Of Publications ◽  
Near Future

Background : The reactivity of 4-(dicyanomethylene)-3-methyl-l-phenyl-2-pyrazoline-5-one DCNP 1 and its derivatives makes it valuable as a building block for the synthesis of heterocyclic compounds like pyrazolo-imidazoles, - thiazoles, spiropyridines, spiropyrroles, spiropyrans and others. As a number of publications have reported on the reactivity of DCNP and its derivatives, we compiled some features of this interesting molecule. Objective: This article aims to review the preparation of DCNP, its reactivity and application in heterocyclic and dyes synthesis. Conclusion: In this review we have provided an overview of recent progress in the chemistry of DCNP and its significance in synthesis of various classes of heterocyclic compounds and dyes. The unique reactivity of DCNP offers unprecedentedly mild reaction conditions for the generation of versatile cynomethylene dyes from a wide range of precursors including amines, α-aminocarboxylic acids, their esters, phenols, malononitriles and azacrown ethers. We anticipate that more innovative transformations involving DCNP will continue to emerge in the near future.

scholarly journals ChCl: Gly (DESs) Promote Environmentally Benign Synthesis of Xanthene Derivatives and Their Antitubercular Activity

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3667
Author(s):  
Mashooq A. Bhat ◽  
Ahmed M. Naglah ◽  
Siddique Akber Ansari ◽  
Hanaa M. Al-Tuwajiria ◽  
Abdullah Al-Dhfyan
Keyword(s):  
Reaction Times ◽  
Antitubercular Activity ◽  
Antimycobacterial Activity ◽  
Environmentally Benign ◽  
Reaction Yield ◽  
Benign Synthesis ◽  
Xanthene Derivatives ◽  
Wide Range ◽  
Major Application

A ChCl: Gly (DESs) promoted environmentally benign method was developed for the first time using the reaction of aryl aldehydes and dimedone to give excellent yields of xanthene analogues. The major application of this present protocol is the use of green solvent, a wide range of substrate, short reaction times, ease of recovery, the recyclability of the catalyst, high reaction yield, and ChCl: Gly as an alternative catalyst and solvent. In addition to this, all the synthesized compounds were evaluated for their in vitro antimycobacterial activity against M. tuberculosis H37Ra (MTB) and M. bovis BCG strains. The compounds 3d, 3e, 3f, and 3j showed significant antitubercular activity against MTB and M. bovis strains with minimum inhibitory concentration (MIC) values of 2.5−15.10 µg/mL and 0.26–14.92 µg/mL, respectively. The compounds 3e, 3f, and 3j were found to be nontoxic against MCF-7, A549, HCT 116, and THP-1 cell lines. All the prepared compounds were confirmed by 1H NMR and 13C NMR analysis.

scholarly journals Using Satellite Data for CBRN (Chemical, Biological, Radiological, and Nuclear) Threat Detection, Monitoring, and Modelling

2021 ◽  
Author(s):  
Gary Sutlieff ◽  
Lucy Berthoud ◽  
Mark Stinchcombe
Keyword(s):  
Satellite Data ◽  
Meteorological Data ◽  
Atmospheric Composition ◽  
Chemical Detection ◽  
List Type ◽  
Data Types ◽  
Wide Range ◽  
Future Technologies ◽  
The Impact ◽  
Near Future

Abstract CBRN (Chemical, Biological, Radiological, and Nuclear) threats are becoming more prevalent, as more entities gain access to modern weapons and industrial technologies and chemicals. This has produced a need for improvements to modelling, detection, and monitoring of these events. While there are currently no dedicated satellites for CBRN purposes, there are a wide range of possibilities for satellite data to contribute to this field, from atmospheric composition and chemical detection to cloud cover, land mapping, and surface property measurements. This study looks at currently available satellite data, including meteorological data such as wind and cloud profiles, surface properties like temperature and humidity, chemical detection, and sounding. Results of this survey revealed several gaps in the available data, particularly concerning biological and radiological detection. The results also suggest that publicly available satellite data largely does not meet the requirements of spatial resolution, coverage, and latency that CBRN detection requires, outside of providing terrain use and building height data for constructing models. Lastly, the study evaluates upcoming instruments, platforms, and satellite technologies to gauge the impact these developments will have in the near future. Improvements in spatial and temporal resolution as well as latency are already becoming possible, and new instruments will fill in the gaps in detection by imaging a wider range of chemicals and other agents and by collecting new data types. This study shows that with developments coming within the next decade, satellites should begin to provide valuable augmentations to CBRN event detection and monitoring. Article Highlights There is a wide range of existing satellite data in fields that are of interest to CBRN detection and monitoring. The data is mostly of insufficient quality (resolution or latency) for the demanding requirements of CBRN modelling for incident control. Future technologies and platforms will improve resolution and latency, making satellite data more viable in the CBRN management field

scholarly journals Influence from cosmological uncertainties on galaxy number count at faint limit

2015 ◽  
Vol 30 (28) ◽  
pp. 1550139
Author(s):  
Keji Shen ◽  
Qiang Zhang ◽  
Xin-He Meng
Keyword(s):  
Galaxy Evolution ◽  
Number Density ◽  
Number Count ◽  
Density Prediction ◽  
Evolution Pattern ◽  
Wide Range ◽  
Different Types ◽  
Physical Cosmology ◽  
Cosmology Observations ◽  
Near Future

Counting galaxy number density with wide range sky surveys has been well adopted in researches focusing on revealing evolution pattern of different types of galaxies. As understood intuitively the astrophysics environment physics is intimately affected by cosmology priors with theoretical estimation or vice versa, or simply stating that the astrophysics effect couples the corresponding cosmology observations or the way backwards. In this paper, we try to quantify the influence on galaxy number density prediction at faint luminosity limit from the uncertainties in cosmology, and how much the uncertainties blur the detection of galaxy evolution, with the hope that this trying may indeed help for precise and physical cosmology study in near future or vice versa.

The Effects of Ambient Conditions on Gas Turbine Emissions—Generalized Correction Factors

1978 ◽  
Vol 100 (4) ◽  
pp. 640-646 ◽  
Author(s):  
P. Donovan ◽  
T. Cackette
Keyword(s):  
Gas Turbine ◽  
Pressure Ratio ◽  
Turbine Engines ◽  
Inlet Temperature ◽  
Gas Turbine Engines ◽  
Correction Factors ◽  
Oxides Of Nitrogen ◽  
Ambient Conditions ◽  
Nitrogen Emission ◽  
Wide Range

A set of factors which reduces the variability due to ambient conditions of the hydrocarbon, carbon monoxide, and oxides of nitrogen emission indices has been developed. These factors can be used to correct an emission index to reference day ambient conditions. The correction factors, which vary with engine rated pressure ratio for NOx and idle pressure ratio for HC and CO, can be applied to a wide range of current technology gas turbine engines. The factors are a function of only the combustor inlet temperature and ambient humidity.

scholarly journals Recent advances in the electrochemical construction of heterocycles

2014 ◽  
Vol 10 ◽  
pp. 2858-2873 ◽  
Author(s):  
Robert Francke
Keyword(s):  
Heterocyclic Compounds ◽  
Elevated Temperatures ◽  
Ring Formation ◽  
Environmentally Benign ◽  
Heterocyclic Chemistry ◽  
Ambient Conditions ◽  
Recent Developments ◽  
Strong Acids ◽  
Selection Of ◽  
Made In

Due to the fact that the major portion of pharmaceuticals and agrochemicals contains heterocyclic units and since the overall number of commercially used heterocyclic compounds is steadily growing, heterocyclic chemistry remains in the focus of the synthetic community. Enormous efforts have been made in the last decades in order to render the production of such compounds more selective and efficient. However, most of the conventional methods for the construction of heterocyclic cores still involve the use of strong acids or bases, the operation at elevated temperatures and/or the use of expensive catalysts and reagents. In this regard, electrosynthesis can provide a milder and more environmentally benign alternative. In fact, numerous examples for the electrochemical construction of heterocycles have been reported in recent years. These cases demonstrate that ring formation can be achieved efficiently under ambient conditions without the use of additional reagents. In order to account for the recent developments in this field, a selection of representative reactions is presented and discussed in this review.

scholarly journals Status and conservation of the giant muntjac Megamuntiacus vuquangensis, and notes on other muntjac species in Laos

Oryx ◽  
1998 ◽  
Vol 32 (1) ◽  
pp. 59-67 ◽  
Author(s):  
R. J. Timmins ◽  
T. D. Evans ◽  
Khamkhoun Khounboline ◽  
Chainoi Sisomphone
Keyword(s):  
Habitat Degradation ◽  
Range Limits ◽  
Restricted Range ◽  
Taxonomic Affinity ◽  
Red Data Book ◽  
Wide Range ◽  
Data Book ◽  
The Common ◽  
Near Future ◽  
Muntiacus Muntjak

The large-antlered, or giant, muntjac Megamuntiacus vuquangensis wasdescribed from Vietnam in 1994 and found concurrently in the Annamite Mountains and nearby hill ranges of central and southern Laos. The northerly and southerly range limits are still unknown. It may occupy a wide range of habitats and is found sympatrically with the common muntjac Muntiacus muntjak. Another muntjac species, the taxonomic affinity of which is as yet undetermined, was recently discovered to occur within its range. The large-antlered muntjac is probably not threatened with extinction in the near future, but in view of its restricted range and threats from habitat degradation and hunting, it should be classified as Vulnerable in the Red Data Book. Its future in Laos is largely dependent on the recently created protected-areas system to maintain large tracts of habitat and reduce hunting pressure.

NUMERICAL ANALYSIS OF FLOW BEHAVIOR IN GAS-LIQUID CYLINDRICAL CYCLONE (GLCC©*) SEPARATORS WITH INLET DESIGN MODIFICATIONS

2021 ◽  
pp. 1-27
Author(s):  
Srinivas Swaroop Kolla ◽  
Ram S. Mohan ◽  
Ovadia Shoham
Keyword(s):  
Numerical Study ◽  
Flow Behavior ◽  
Low Cost ◽  
Field Application ◽  
Attractive Alternative ◽  
Inlet Section ◽  
Wide Range ◽  
Cylindrical Cyclone ◽  
Light Oil ◽  
Section Design

Abstract The Gas-Liquid Cylindrical Cyclone (GLCC©*) is a simple, compact and low-cost separator, which provides an economically attractive alternative to conventional gravity-based separators over a wide range of applications. More than 6,500 GLCC©'s have been installed in the field to date around the world over the past 2 decades. The GLCC© inlet section design is a key parameter, which is crucial for its performance and proper operation. The flow behavior in the GLCC© body is highly dependent on the fluid velocities generated at the reduced area nozzle inlet. An earlier study (Kolla et al. [1]) recommended design modifications to the inlet section, based on safety and structural robustness. It is important to ensure that these proposed configuration modifications do not adversely affect the flow behavior at the inlet and the overall performance of the GLCC©. This paper presents a numerical study utilizing specific GLCC© field application working under 3 different case studies representing the flow entering the GLCC, separating light oil, steam flooded wells in Minas, Indonesia. Commercially available Computational Fluid Dynamics (CFD) software is utilized to analyze the hydrodynamics of flow with the proposed modifications of the inlet section for GLCC© field applications.

Ambient Condition Effects on NOx and CO Emissions From Process Heaters

2008 ◽  
Author(s):  
Wesley R. Bussman ◽  
Charles E. Baukal
Keyword(s):  
Atmospheric Pressure ◽  
Ambient Air ◽  
Operating Conditions ◽  
Nox Emissions ◽  
Ambient Conditions ◽  
Fuel Gas ◽  
Natural Draft ◽  
Actual Operating ◽  
Wide Range ◽  
Pollution Emissions

Because process heaters are typically located outside, their operation is subject to the weather. Heaters are typically tuned at a given set of conditions; however, the actual operating conditions may vary dramatically from season to season and sometimes even within a given day. Wind, ambient air temperature, ambient air humidity, and atmospheric pressure can all significantly impact the O2 level, which impacts both the thermal efficiency and the pollution emissions from a process heater. Unfortunately, most natural draft process burners are manually controlled on an infrequent basis. This paper shows how changing ambient conditions can considerably impact both CO and NOx emissions if proper adjustments are not made as the ambient conditions change. Data will be presented for a wide range of operating conditions to show how much the CO and NOx emissions can be affected by changes in the ambient conditions for fuel gas fired natural draft process heaters, which are the most common type used in the hydrocarbon and petrochemical industries. Some type of automated burner control, which is virtually non-existent today in this application, is recommended to adjust for the variations in ambient conditions.

scholarly journals Immunity Boosting Medicinal Plants to Beat Covid -19 in Seraj Block of Mandi District, Himachal Pradesh

2021 ◽  
Vol 2 (4) ◽  
pp. 44-56
Author(s):  
Manju Lata ◽  
Mohammad Jamali
Keyword(s):  
Clinical Trials ◽  
Drug Therapy ◽  
Medicinal Plants ◽  
Curcuma Longa ◽  
Taraxacum Officinale ◽  
Urtica Dioica ◽  
Ocimum Sanctum ◽  
Wide Range ◽  
Herbal Plants ◽  
Near Future

Purpose: This study aimed to document the present status of medicinal plants used to boost the immunity to combat Coronavirus. Materials and Methods: For the assessment and use of herbs during the Covid 19 pandemic, surveys were conducted in different villages of  Seraj block. The surveys were conducted during the spread of the pandemic from 2020 to 2021. Local people were interviewed and information on the utilization of local herbs during this pandemic was recorded. Information on parts used, the procedure of use, habit, habitat, etc. was also collected. Results: A total of 58 species of medicinal plants from 27 families and 42 genera were documented. Among them, the most dominant family was Rosaceae.  Most of the plants such as Morchella sp, Naustratium officinale,Taraxacum officinale ,Urtica dioica ,Allium sp,Withania foraminifera, Curcuma longa, Cannabis, Mentha, Ocimum sanctum are rich in antioxidants and have a wide range of medicinal values used to treat cough, cold, fever, and bronchitis. All these plants were used traditionally to boost immunity. Due to the covid -19 pandemic, the utilization of these herbal plants has increased many folds in the area. These medicinal plants should be made available to scientists to design clinical trials. Integration of this concept would certainly develop drug therapy in the near future. Conclusion: The study found that the use of medicinal plants has increased during COVID-19 and most of the respondents recommended medicinal plants to prevent COVID-19 and to boost immunity. More studies should be conducted to develop certain formulations.

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