scholarly journals Selenium dan Vitamin C Sebagai Pengobatan Pencegahan Pada Keracunan Pestisida (Studi Eksperimen Pada Petani Penyemprot di Temanggung Jawa Tengah)

2020 ◽  
Vol 19 (1) ◽  
pp. 5-9
Author(s):  
Ari Suwondo

Latar belakang: Gejala keracunan organofosfat adalah hasil dari menghalangi aktivitas enzim cholinesterase darah (ChEA). Kemampuan hati untuk melakukan de toxin menggunakan jalur O-Dealchylation pada organofosfat dan cholinesterase yang diikat dan dibantu oleh enzim Glutathione peroxides (GPX) memiliki peran penting dalam mengembalikan level ChEA ke level normal. GPX tergantung pada keberadaan selenium. Tujuan dari penelitian ini adalah untuk mendapatkan manfaat yang lebih dimengerti dari penambahan selenium dan vitamin C terhadap tingkat ChEA, GPX dan hemoglobin dari para petani yang bekerja sebagai penyemprot pestisida.Metode: Merupakan penelitian eksperimental menggunakan Desain Kelompok Kontrol pretest-posttest. Sembilan puluh sembilan responden di desa Pasuruan, Kecamatan Bulu, Temanggung yang memenuhi kriteria inklusi dan eksklusi dipilih sebagai sampel penelitian. Sampel dibagi menjadi 3 kelompok yang terdiri dari 33 orang. Kelompok pertama hanya menerima Selenium, kelompok kedua menerima Selenium dan Vitamin C dan kelompok ketiga adalah kelompok kontrol (tidak diberikan suplemen). Sampel darah dari semua sampel penelitian diambil untuk mengidentifikasi tingkat ChEA, GPX dan hemoglobin sebelum dan sesudah percobaan  Hasil: Tingkat ChEA pada kelompok pertama dibandingkan dengan kelompok ketiga berbeda nyata (p = 0,05). Temuan serupa juga ditemukan untuk tingkat ChEA pada kelompok kedua dibandingkan dengan kelompok ketiga (p = 0,014). Suplementasi Selenium 200 μg selama 7 hari di antara petani penyemprot pestisida meningkatkan kadar ChEA 1,85% dan kadar hemoglobin 2,66%.Simpulan: Terdapat perbedaan yang significant antara tingkat ChEA pada kelompok pertama dibandingkan dengan kelompok lainnya.   Kata kunci: Selenium, Vit C, tingkat GPX, ChEA dan HemoglobinABSTRACT Title: Selenium and Vitamin C As a Preventive Medicine for Pesticide Poisoning (Experimental Study on Spraying Farmers in Temanggung, Central Java) Background: Symptoms of organophosphate intoxication are a result of blocking the activity of blood cholinesterase enzyme (ChEA).   The ability of liver to do de toxification using pathway of O-Dealchylation on organophosphate and cholinesterase bound and helped out by Glutathione peroxides enzyme (GPX) has important role in returning the level of ChEA to the normal level. GPX is dependent on the presence of selenium. The objective of this study is to obtain more understandable benefit of adding selenium and vitamin C towards the ChEA, GPX and hemoglobin level of farmers worked as pesticide sprayers.Method: This is an experimental study using Pretest-posttest Control Group Design.  Ninety nine respondents in Pasuruan village, sub district of Bulu, Temanggung  who fulfilled inclusion and exclusion criteria were selected as study samples. Samples were divided into 3 groups of 33 people. First group received only Selenium, second group received Selenium and Vitamin C and third group is a control group (no supplementation given). Blood samples of all study samples were taken to identify the level of ChEA, GPX and hemoglobin before and after experimentResult: Level of ChEA in the first group compared with the third group was significantly different (p=0.05). Similar finding was also found for the level of ChEA in second group compared with third group (p= 0.014). Supplementation of Selenium 200 µg for 7 days among pesticides sprayers farmers increase 1.85% level of ChEA and 2.66% level of hemoglobin.Conclusion: There is a significant difference between ChEA levels in the first group compared to other groups Keywords: Selenium, vit C, level of GPX, ChEA and Hemoglobin.

2017 ◽  
Vol 3 (4) ◽  
pp. 438-442
Author(s):  
Agrystina Ryma Melati ◽  
C Tjahjono Kuntjoro ◽  
Sri Sumarni ◽  
Kamilah Hidayati ◽  
Rr. Sri Endang Pujiastuti

Background: The prevalence of skinny infants in Indonesia is still high. Baby's Spa is considered to be able increase infant’s weight.Objective: To determine the effectivity of baby spa in infant weight in in Bebengan Village, Boja Sub District, Kendal Regency, Central Java, IndonesiaMethods: This study was a quasy-experimental study with non-equivalent control group design. There were 38 infants were selected using purposive sampling, divided into 3 groups, namely: 1) a group received Spa 2 times per week (12 infants), 2) a group received spa 3 times per week (13 infants), and 3) a control group. Baby digital scale of ARN-EBSD-04 was used to measure infant weight. Data were analyzed using paired t-test and ANOVA.Results: There was statistically significant effect of intervention in each group on the infant’s weight. However, the data showed that the intervention that had a better effect on infant weight was the intervention of spa in two times per week with mean difference before and after intervention of 603 g.Conclusions: Spa in 2 times per week could significantly increase infant weight effectively. Therefore, it is recommended for midwife to apply this intervention to increase the weight gain of babies and to reduce the number of skinny infants in Indonesia.


2020 ◽  
Vol 1 (2) ◽  
pp. 16-24
Author(s):  
Tri Putri Ageng Utami

Introduction: Anemia is a biggest health in the world. According to WHO the prevalence of anemia in pregnant women was 41,8%. Based on the results of Riskesdas that the proportion of anemia in pregnant women in 2013 was 37,1% and in 2018 of 48,9%. To prevent anemia, pregnant women are expected to get at least 90 iron tablets during pregnancy and consume iron-rich foods. Avocados have the nutrients of vitamin C, vitamin E, vitamin K, iron, folic acid, potassium, calories and fat. Iron in avocados is useful for the formation of red blood cells, preventing and treating anemia. Vitamin C helps to absorb iron and calcium Methods: This study aims to determine the effect of Fe + avocado juice (Persea Americana Mill) to haemoglobin levels of second trimester pregnant women in Suryani independent clinic of Medan Johor sub district in 2019. This type of research was Quasi Experiment with Pre Test and Post Test With Control Group Design. The population of this research was all 42 pregnant women with 30 purposive sampling techniques. Results and Discussion: Based on the collection and analysis of data with an average result of haemoglobin in second trimester pregnant women increased by 0,87 gr/dl in the intervention group and 0,8 gr/dl in the control group. There are significant differences between before and after treartment in the intervention group and the control group. In the intervention group and the control group before the treatment there can be no difference which means the data is homogeneous and after the treatment there can be no significant difference which means that Ho is accepted and Ha is rejected. Conclusion: Pregnant women who have Hb levels below normal may be given Fe tablets alone or can be combined to consume avocado juice.


2017 ◽  
Vol 5 (5) ◽  
pp. 300-311
Author(s):  
June Venelee A. Delgado ◽  
Victor D. Villaganas ◽  
Adora A. Villaganas ◽  
Reynaldo B. Inocian

This study assessed the performance level of Grade IX students in Mathematics after being exposed to conventional teaching approach (CTA) and the eclectic teaching approach. It intended to: (1) describe the profile of students in Mathematics; (2) determine the performance level of students in the pretest and posttest; (3) compare the significant mean improvement from the pretest to the posttest; and (4) find out the significant difference in mean gains of students exposed to both approaches. This experimental study compared the effectiveness of CTA and ETA based on the students’ performance level before and after the exposure of these approaches, using the Pretest-Posttest Control Group Design. The students’ performance in Section A with CTA and Section B with ETA was low in the pretest, with a minimal improvement in the posttest. No significance in pre-post mean gain was found out in the performance of students in Mathematics IX using both CTA and ETA. Moreover, it was determined that there was no significant mean gain difference between the students’ performance in CTA and ETA, which proved that the effectiveness of these approaches were comparable.  The findings indicate that ETA can be an alternative way to CTA.


2018 ◽  
Vol 4 (2) ◽  
pp. 195-201
Author(s):  
Anna Jumatul Laely ◽  
Awal Prasetyo ◽  
Chandra Bagus Ropyanto

Background: Physical responses that occur in patients with nasopharyngeal cancer are the emergence of pain due to the effects of treatment. The problem of pain in these patients at the stage of treatment remains critical to solve because it can cause comorbidity, psychological trauma and mortality. Mindfulness intervention is considered useful in transforming consciousness into the stage of acceptance.Objective: This study aims to determine the effect of mindfulness intervention on the intensity of pain in nasopharyngeal cancer patients undergoing radiation treatment.Methods: This was a quasy-experimental study with pretest posttest control group design. Thirty patients were selected using consecutive sampling, which divided into experiment and control group. Visual Analogue Scale (VAS) was used to measure pain. Each respondent received mindfulness intervention for 6 sessions, divided into 3 meetings. Paired t-test was used for data analysis.Results: The results showed a significant reduction of pain from 4.12 (moderate pain) to 3.06 (mild pain) in the experiment group. There was a significant difference in pain level before and after mindfulness intervention (p= 0.001).Conclusion: Mindfulness is effective in reducing pain intensity level in nasopharyngeal cancer patients undergoing radiation therapy.


Author(s):  
Susanti Susanti

The lack of use the writing skills method raises several obstacles experienced by students, including weaknesses in understanding the basics of Arabic writing and difficulty in answering Arabic questions. Therefore, it is necessary to improve learning as an effort to improve writing skills by applying the imla’ manzur method. This research is an experimental study with a pretest-posttest control group design model, aimed at finding out the effectiveness of the imla’ manzur method. Data collection techniques in this study used observation, tests, questionnaires, interviews, and documentation. Then the validity of the data is tested using the independent sample t-test. The results obtained were that in the experimental class the mastery of Arabic writing skills of students after applying the imla’ manzur method had increased the average value from 52.08 to 78.57. Then, the results of the independent sample t-test showed a significant difference in the mastery of Arabic writing skills in the experimental class and the control class 0.000 < 0.05 after treatment, so that the conclusion of this study based on the data obtained showed that the application of the imla’ manzur method was effective in improving students Arabic writing skills. Evidenced by a significant increase in learning outcomes, student enthusiasm when taking turns to write vocabulary and sentences in Arabic on the board, as well as growing sensitivity of student analysis of Arabic writing skills.


2014 ◽  
Vol 13 (1) ◽  
pp. 28
Author(s):  
Muhammad Ilyas ◽  
Clarissa Phielip

The main objective of caries prevention programs in the community is to reduce the number of colonies of cariogenicbacteria, especially Streptococcus. A method of caries preventionthat is currently developed is a method using probioticsthrough yogurt. This research is a laboratory based experiment using the cross over with control group design. Fifteensamples were collected randomly from a population of preclinical dentistry students of Hasanuddin University fromentry year 2008 until 2010. The results showed a significant difference between before and after drinking yogurt wherethe number of colonies of cariogenic bacteria in saliva reduced (p<0.05)and there is also a significant differencebetween the temperature of the yogurt in reducing the average number of cariogenic bacteria in the saliva after six andnine days yogurt consumption (p<0.05). In addition, there is a significant difference pH of saliva between before andafter drinking yoghurt (p <0.05). It is concluded that drinking yogurt reducts colony of cariogenic bacteria in youngadult saliva


Author(s):  
Dyah Dyah Dewi ◽  
Wiwik Wiwik Kusumawati ◽  
Ismarwati Ismarwati Ismarwati

Background: Maternal Mortality Rate (MMR) as an indicator of maternal health during pregnancy, childbirth, and childbirth. Anemia contributes 20% to the incidence of maternal deaths caused by bleeding during labor. The government prevents anemia by giving iron tablets at least 90 tablets for pregnant women. However, the prevalence of anemia remains high, because of the low adherence in consuming Fe tablets every day. Self-efficacy adherence is a predictor of health behavior and adherence to treatment.Objective: To improve adherence with self-efficacy in consuming Fe tablets in pregnant women with health promotion and WhatsApp reminder in Yogyakarta City Health Center.Method: This study used a quasi-experiment method with a pre-test post-test non-equivalent control group design. The sample amounted to 59, the sampling technique used was consecutive sampling which was taken by random sampling technique in which samples were taken alternately to determine the intervention group and the control group.Results: There were significant differences in the self efficacy score between the intervention groups (Mean = 6.30, SD = 8.11) and the control group (Mean = 0.89, SD = 7.83) with t-test = 2.60 and ρ = 0.012.Conclusion: There is a significant difference in self-efficacy adherence with consuming Fe tablets in pregnant women before and after being given health promotion and WhatsApp reminder intervention and control groups. Health service agencies can consider the combined service between health promotion and WhatsApp reminder to improve self-efficacy in adhering to consuming Fe tablets in increasing Hb levels in anemic pregnant women.


2017 ◽  
Vol 5 (2) ◽  
pp. 98-104
Author(s):  
Dewi Pertiwi Dyah Kusudaryati ◽  
Siti Fatimah Muis ◽  
Laksmi Widajanti

Background : Zn supplementation on stunted children in multiple research get the result inconsistent concerning the effect of Zn on children’s growth.Objective : To examine the effect of Zn supplementation to the change in height for index among stunted children age between 24-36 months.Methods: The research design is randomized pretest posttest control group design. The total of thirty six stunted children are divided into two groups. The treatment group is received syrup with 20 mg ZnSO4 twice a week for three months. The control group received placebo without Zn. Height for age z score (HAZ) on WHO Child Growth 2006 is used to measure height for age index while dietary intake and infection diseases are used as confounding variables.Result : There is significant difference in HAZ before and after supplementation at treatment group (p<0.001) and control group (p<0.001). There is a significant difference of the change in HAZ between the treatment group and control group (p=0.006). Percentage Achievement of Energy, Protein, and Zn Dietary Allowance have significant difference between the treatment group and control group (p=0.009; p<0.001; p<0.001, respectively). The change in HAZ, Percentage Achievement of Energy, Protein, and Zn Dietary Allowance are higher in treatment group than control group. Duration of diarrhea (p=0.045) and morbidity (p=0.019) are lower in treatment group than control group. Conclusion : Zn Supplementation among stunted children have significant effect on the change in HAZ, dietary intake, and infection.


Konselor ◽  
2015 ◽  
Vol 4 (2) ◽  
pp. 84
Author(s):  
Mirnayenti Mirnayenti ◽  
Syahniar Syahniar ◽  
Alizamar Alizamar

Individual attitudes can occur because of social interaction. Some learners anyone dared to oppose, silent and engaged in acts of bullying, so that the necessary efforts to improve anti-bullying stance. The attitude of the students towards bullying that can be seen in the journal cases BK teacher / school counselor. One of the efforts made in improving the anti bullying learners with information services. This study aimed to test the effectiveness of media information services using animation to enhance the anti-bullying attitudes of learners. This study uses quantitative methods. This research is a Quasi Experiment with pretest-posttest control group design. The study population was students of SMPN 13 Padang as EG and SMP 12 Padang as CG and samples selected using purposive sampling technique. The research instrument used Likert Scale models, then analyzed using the t-test with SPSS version 17. The findings of this study are: (1) there is a significant difference between anti bullying learners EG before and after following the service information using animation media, (2) there is a difference between the attitude of anti-bullying learners KK before and after following the service information without the use of animation media , (3) there is a difference in attitude differences anti bullying learners CG given treatment information services using animation media, with families given treatment information services without the use of animation media. Based on the above findings, we can conclude that the service information using animation media effectively improve anti-bullying attitudes of learners. 


2020 ◽  
Vol 9 (4) ◽  
pp. 465-476
Author(s):  
E. Purwaningsih ◽  
S. P. Sari ◽  
A. M. Sari ◽  
A. Suryadi

This study aims to investigate the effect of Science, Technology, Engineering, and Mathematics-Project Based Learning (STEM-PjBL) and discovery learning on students' problem-solving abilities. The research is a Quasi-Experiment with a Nonequivalent Pretest-Posttest Control Group Design. The participants involved are 53 students of class X from a high school in Malang, where 28 students studied with STEM-PjBL, and 25 students studied with discovery learning. This research was conducted on the subject of impulse and momentum. In this analysis, researchers have developed problem-solving tools with a particular field approach to impulse and momentum topics in order to obtain an instrument with a reliability of  0.81. This instrument collects student problem-solving data before and after learning both in the experimental class and in the comparison class. Problem-solving skills data were analyzed using descriptive statistics and inferential statistics. The results showed a significant difference in the scores of students' problem-solving abilities in the experimental class and the comparison class (p<0.05). The problem-solving ability in the experimental class (Md=78.74) was higher than the comparison class (Md=70.00). In STEM-PjBL learning, students are better trained and challenged to solve problems in everyday life. Compared to the comparison class, learning in the experimental class is more able to accommodate students' ideas and make students more interested in learning. In conclusion, STEM-PjBL has a significant positive effect on improving students' problem-solving abilities rather than discovery learning.


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