scholarly journals Potential risks related to anabolic steroids use on nervous, cardiovascular and reproductive systems disorders in men

2018 ◽  
Vol 31 (3) ◽  
pp. 135-159 ◽  
Author(s):  
Agnieszka Kujawska ◽  
Joanna Androsiuk-Perkowska ◽  
Jakub Husejko ◽  
Marcin Kozuchowski ◽  
Daria Bieniek ◽  
...  

AbstractAnabolic steroids (AS) have been a subject of intensive research for the last several decades. Due to wide use of AS in pharmacological treatment and in professional and amateur sport, it is, hence, worthwhile to describe the biochemical mechanism of the effects of AS usage in humans and its potential health risks. In this work, the relationship between diet and its effect on the level of testosterone in blood is described. Testosterone affects the nervous system, however, there is need for further researches to examine the influence of AS therapy on emotional and cognitive functioning. AS therapy has known negative effects on the cardiovascular system: cardiac hypertrophy can occur, blood pressure can vastly increased, thrombotic complications can come about. These effects are observed not only in patients who are treated with AS, but also in athletes. The paper also describes the relationship between AS and reproductive system diseases. Decreased libido and erectile dysfunction are only some of the many side effects of an incorrect AS treatment.

2021 ◽  
Vol 100 (12) ◽  
pp. 1481-1486
Author(s):  
Olga G. Bogdanova ◽  
Natalia V. Efimova ◽  
Olga A. Molchanova

Introduction. Aim. Selection of priority safety indicators and optimal research scope through analysis of potential health risks associated with chemical and microbiological safety of food products (FP). Materials and methods. Retrospectively analyzed data on chemical and microbiological safety of FP addressed on the consumer market of the Republic of Buryatia for 2016-2020. Assessment of the potential risk of harm to human health included prediction performed on linear regression models. Results. The maximum probability of violations of mandatory requirements for chemical and microbiological contamination was noted for dairy products. The minimum probability of violations was identified for the biologically active additives and industrial baby FP. The calculation of potential risks to consumer health based on the results of studies of FP revealed the categories of “high risk” - fish and seafood, “significant risk” - dairy products, confectionery, vegetables, melons, soft drinks. It was found that the supply of fish and seafood, poultry and poultry products had long supply chains, when the risks associated with non-compliance with their transportation and storage conditions were most likely Correlations were revealed between the risk level according to the microbiological criterion associated with the contamination of food, fish, culinary products, poultry meat and the incidence of acute intestinal infections. The indicated factor signs determine from 28.6% to 67.0% of the variance of the incidence. Conclusion. Identification of potential risks of harm to the public health related to FP safety indicates the need for further monitoring of the content of chemical and microbiological contaminants.


Author(s):  
Carlos H. Pinzón-Bedoya ◽  
Martha L. Pinzón-Bedoya ◽  
José Pinedo-Hernández ◽  
Iván Urango-Cardenas ◽  
José Marrugo-Negrete

This study assesses the potential human health risks posed by six heavy metals (Hg, As, Pb, Cd, Cu, and Zn) found in five of the most consumed fish species (Mugil incilis, Centropomus undecimalis, Cathorops mapale, Eugerres plumieri, and Elops smithi) collected by the riverine population living in Ciénaga Grande de Santa Marta (CGSM), the largest estuary in Colombia. Metal concentrations were low compared with those reported in other regions around the world and the maximum value established by international monitoring organizations. The estimation of the potential risk (HQ) indicated that Cu and Hg could generate negative effects in groups of women of childbearing age (WCA) and the remaining population (RP), because they exceeded their related reference doses, with HQ values > 1; however, Cu and Hg concentrations were not high in fish and EWI, MFW, or MeHgPSL values shows that there is no evidence of a potential health risk from MeHg exposure in the study population. Therefore, the recommendations are to establish continuous monitoring of heavy metals together with strategies that address the high fish consumption, as well as to implement mechanisms for the mitigation of contamination of the watershed, to ensure the safety of organisms in the ecosystem and human health, not only of populations who depend on aquatic resources in the area but also of those that market and consume these resources in the Colombian Caribbean.


2014 ◽  
pp. 69-75 ◽  
Author(s):  
Maneerat Ongwandee ◽  
Thabtim Chatsuvan ◽  
Theerapong Sairat ◽  
Kritsanaphong Lephol

Passenger exposure to volatile organic compounds (VOCs) emitted from vehicle interiors hasincreasingly drawn public concern over their potential health risks. This study aimed to investigate ambient levels of in-cabin VOCs in a new car over the period of one year after first delivery. The relationship between VOC concentrations and in-cabin temperature was also studied. Seventeen active air samplings inside a parked new car were conducted from February 2012 to February 2013 using sorbent tubes. Six VOCs were measured with first-month average concentrations of 215 μgm-3for benzene, 65.6 μgm-3for toluene, 151 μgm-3for 1,2,3-trimethylbenzene, 806 μgm-3for ethyl acetate, 183 μgm-3for formaldehyde, and 28.2 μgm-3for acetone. The concentration profiles of all VOCs except formaldehyde declined, falling below the detection limits towards theend of the 1-year monitoring period. Formaldehyde concentrations were found to be directly proportional to in-cabin temperature at a significance level of p=0.05 during the first five months.


2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Louis G. Lategan ◽  
Shayne Erasmus ◽  
Markus Zietsman ◽  
Elizelle J. Cilliers ◽  
Mario Wolf ◽  
...  

Informal backyard rentals (IBRs) constitute South Africa’s fastest growing housing subsector, flourishing within a relative research vacuum and without national policy intervention to address the vulnerabilities of stakeholders to the health risks potentially presented. This article reviewed the literature on IBRs, focussing on past policies and interventions, general characteristics, infrastructure and service access to inform an analysis of potential health risks from the existing literature to guide future research and policy-making. Research followed a qualitative approach to review IBR literature dating after 2004. Relevant publications were identified from bibliographic databases using Boolean search logic and by reviewing citations in and later citations of these publications. Relevant secondary sources were also included. The review evidenced that IBRs have received increasing policy, but limited research attention, and that health hazards have been particularly neglected. Although issues such as shared water and sanitation, inappropriate waste disposal, poor hygiene practices, high densities and poor quality structures have been referenced extensively – alluding to risks and health concerns – few studies have focussed directly on health, risk and vulnerability. The risk analysis completed based on the literature made potential risks explicit, exemplified by references to specific conditions, such as HIV/AIDS, tuberculosis and the coronavirus pandemic, demonstrating pathogenic pathways, contamination and transmission risks conducive to poor health, infection and potential disaster. The review captured and updated the contemporary literature on IBRs, with the subsequent analysis providing a platform for future empirical research on health, infrastructure and IBRs to address potential risks towards positive change in future policies.


2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Shaofeng Yuan ◽  
Ying Gao

PurposeThis study investigated the potential negative effects of a sponsored team's losing performance on audiences' trust and purchase intention toward the sponsoring brand. Shedding light on the moderating role of sponsoring brand familiarity among audiences and audience team identification regarding such negative effects, the study establishes when sports sponsorship may incur risk to a sponsoring brand.Design/methodology/approachThree experimental designs (audience as stimulus of a team's losing vs control condition) were used to indicate whether and when losing performance influences participants' trust and purchase intention toward the sponsoring brand.FindingsThe participants in the losing condition report lower brand trust and purchase intention. Brand trust mediates the relationship between losing results and decreased purchase intention. The negative effects of losing on brand trust and purchase intention only appear when the sponsoring brand has low familiarity among audiences and only for audiences with low identification.Practical implicationsThe strategy of a brand with low familiarity sponsoring a team that frequently loses has risks and is not worth advocating. However, if an unknown brand has already sponsored a team that often loses, the efforts to cultivate audiences' identification with the team can reduce the potential risks.Originality/valueThe affirmed negative effects of losing performance on brand trust and purchase intention have value for firm sponsorship decisions. This study contributes to the sponsorship literature by revealing two boundary conditions (sponsoring brand familiarity and audiences' team identification) for those negative effects.


2019 ◽  
pp. 46-64 ◽  
Author(s):  
Vladimir V. Klimanov ◽  
Sofiya М. Kazakova ◽  
Anna A. Mikhaylova

The article examines the impact of various socio-economic and financial indicators on the resilience of Russian regions. For each region, the integral index of resilience is calculated, and its correlation dependence with the selected indicators is revealed. The study confirms the relationship between fiscal resilience and socio-economic resilience of the regions. The analysis of panel data for 75 regions from 2007 to 2016 shows that there are significant differences in the dynamics of indicators in different periods. In particular, the degree of exposure to the negative effects of the crises of 2008—2009 and 2014—2015 in non-resilient regions is higher than in resilient ones.


Author(s):  
Michael O’Toole

In this article I examine aspects of the relationship between mothers and sons from an attachment perspective in an Irish context. Through the works of Irish writers such as Seamus Heaney, John McGahern, and Colm Tóibín, I focus on particular aspects of this relationship, which fails to support the developmental processes of separation and individuation in the many men who come to me for psychotherapy. I illustrate key points concerning this attachment dynamic through the use of clinical examples of my work with two men from my practice. While acknowledging that many other cultural factors play a significant role in the emotional development of children, integrating the work of our poets, novelists, and scholars with an attachment perspective


2015 ◽  
Vol 33 (1) ◽  
pp. 1-15
Author(s):  
Henrietta Bannerman

John Cranko's dramatic and theatrically powerful Antigone (1959) disappeared from the ballet repertory in 1966 and this essay calls for a reappraisal and restaging of the work for 21st century audiences. Created in a post-World War II environment, and in the wake of appearances in London by the Martha Graham Company and Jerome Robbins’ Ballets USA, I point to American influences in Cranko's choreography. However, the discussion of the Greek-themed Antigone involves detailed consideration of the relationship between the ballet and the ancient dramas which inspired it, especially as the programme notes accompanying performances emphasised its Sophoclean source but failed to recognise that Cranko mainly based his ballet on an early play by Jean Racine. As Antigone derives from tragic drama, the essay investigates catharsis, one of the many principles that Aristotle delineated in the Poetics. This well-known effect is produced by Greek tragedies but the critics of the era complained about its lack in Cranko's ballet – views which I challenge. There is also an investigation of the role of Antigone, both in the play and in the ballet, and since Cranko created the role for Svetlana Beriosova, I reflect on memories of Beriosova's interpretation supported by more recent viewings of Edmée Wood's 1959 film.


2017 ◽  
Vol 7 (2) ◽  
pp. 159
Author(s):  
Eva Krisna

“Batombe” is an oral tradition of the Nagari Abai society at Sangir Batanghari Subdistrict, South Solok District, West Sumatra Province. Batombe is exchanging rhymes (berbalas pantun) which is performed as an entertainment on the wedding party (baralek). Batombe is identical with Great House (Rumah Gadang) Nagari Abai which is a unique house because it is a long traditional custom house that has many rooms. It reaches 21 rooms. The rhymes in batombe tends to deliver a feeling of lilting so the singers often drift into the atmosphere of the show. Therefore, as part of community life, batombe often cause a negative effects for the singers soul. This paper describes various things, such as: who batombe singer is; the time to perform this activity; the relationship between batombe and Great House (Rumah Gadang) at Nagari Abai; and the negative effects caused by batombe for the singers. This paper based on the fact that in oral tradition there is a close relationship between text and the speakers and text with context (place, time and atmosphere), a multidisciplinary approach is used in this paper, such as historical, sociological, anthropological, and psychological approach. The method used is descriptive analysis method.AbstrakBatombe adalah tradisi lisan masyarakat Nagari Abai, Kecamatan Sangir Batanghari, Kabupaten Solok Selatan, Provinsi Sumatra Barat. Batombe adalah tradisi berbalas pantun yang dilakukan sebagai hiburan pada pesta pernikahan (baralek). Batombe identik dengan rumah gadang Nagari Abai yang unik, yakni rumah adat dengan ruangan yang sangat panjang hingga 21 ruangan. Pantun-pantun batombe cenderung menyampaikan perasaan yang mendayu-dayu sehingga para pedendangnya sering hanyut ke dalam suasana pertunjukan. Oleh sebab itu, sebagai bagian dari kehidupan masyarakat, seringkali batombe menyebabkan efek negatif bagi (kejiwaan) para pedendangnya. Tulisan ini mendeskripsikan berbagai hal, seperti penutur batombe, waktu untuk melakukan batombe, hubungan batombe dengan rumah gadang di Nagari Abai, dan efek negatif yang ditimbulkan batombe bagi pedendangnya. Tulisan ini bertolak dari kenyataan bahwa pada tradisi lisan terdapat hubungan erat, antara lain seperti teks dengan penutur dan teks dengan konteks (tempat, waktu, dan suasana). Pendekatan multidisipliner digunakan pada tulisan ini, yakni pendekatan historis, sosiologis, antropologis, dan psikologis. Metode yang digunakan adalah metode analisis deskriptif.


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