Leptin and neuropeptide Y levels in newborns

2016 ◽  
Vol 29 (1) ◽  
Author(s):  
Avni Kaya ◽  
Zerrin Orbak ◽  
İsmail Polat ◽  
Harun Polat ◽  
Musa Gümüşdere
Keyword(s):  
Body Weight ◽  
Prospective Study ◽  
Neuropeptide Y ◽  
Neonatal Period ◽  
Medical Faculty ◽  
Faculty Research ◽  
Research Hospital ◽  
Significant Difference ◽  
The Mean ◽  
Plasma Leptin

AbstractSeveral studies have investigated leptin and neuropeptide Y (NPY) levels in children, but the information for newborns in the literature is limited. The purpose of this study was to determine leptin and NPY levels in 14- to 28-day-old newborns.This prospective study was performed in Atatürk University Medical Faculty Research Hospital Neonatal Clinic, Erzurum, Turkey between July and December, 2014. Sixty-two 14- to 28-day-old neonates, 26 female and 36 male, were included. Age, height, and body weight of the patients were recorded. Feeding status was also recorded. The newborns were divided into two groups – those receiving breastfeeding only and those receiving breastfeeding and formula. Plasma leptin levels were measured using enzyme amplified sensitivity immunoassay (EASIA).The mean leptin level in 14- to 28-day-old female neonates was 4.25±3.08 ng/mL, and the mean NPY level was 24.79±9.87 ng/mL. The mean leptin level in 14- to 28-day male neonates was 3.49±2.52 ng/mL, and the mean NPY level was 25.80±9.58 ng/mL. No significant difference was determined between leptin (p=0.228) or NPY (p=0.144) in terms of feeding status. No significant difference was also observed between the sex in terms of leptin or NPY levels (leptin p=0.775 and NPY p=0.687).There were no differences in terms of feeding status and sex in leptin and NPY levels in the neonatal period.

Serum leptin levels in patients with nasal polyposis

2007 ◽  
Vol 122 (6) ◽  
pp. 590-592 ◽  
Author(s):  
M Guven ◽  
Y Bulut ◽  
I Aladag ◽  
K Yelken ◽  
H Erdoğan
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Energy Expenditure ◽  
Inflammatory Response ◽  
Prospective Study ◽  
Nasal Polyposis ◽  
Primary Role ◽  
Serum Leptin ◽  
Significant Difference ◽  
The Mean

AbstractBackground:Nasal polyposis is one of the most common inflammatory pathologies of the nasal cavity. The aetiopathogenetic mechanisms of nasal polyp formation are still unclear.Objectives:The aim of this study was to investigate the serum leptin levels in patients with nasal polyposis.Design:A randomised, prospective study was performed of 28 adult patients with nasal polyposis and 22 control subjects of a similar age, sex and body mass index.Results:Serum leptin levels were 12.10 ± 9.39 ng/ml in the nasal polyposis patients and 6.17 ± 7.68 ng/ml in the controls. A significant difference (p = 0.021) was observed in the mean serum leptin levels between nasal polyposis patients and controls.Conclusion:Serum leptin levels were found to be significantly higher in patients with nasal polyposis. Leptin, apart from its primary role in the regulation of body weight and energy expenditure, may have a role in the inflammatory response of nasal polyposis.

scholarly journals THE EFFECT OF DEXAMETHASONE ON SPERMATOGONIUM AND SERTOLI CELL OF IPSILATERAL TESTIS IN UNILATERAL TESTICULAR TORSION WISTAR RAT

2018 ◽  
Vol 25 (2) ◽  
Author(s):  
Ferdyan Rachmat Efendi ◽  
Johan Renaldo ◽  
Tarmono Djojodimedjo
Keyword(s):  
Body Weight ◽  
Sertoli Cell ◽  
Sertoli Cells ◽  
Testicular Torsion ◽  
Wistar Rat ◽  
Male Rats ◽  
Sham Operation ◽  
Group I ◽  
Significant Difference ◽  
The Mean

Objective: To investigate the effect of dexamethasone on spermatogonium and sertoli cell of ipsilateral testis in unilateral testicular torsion strain wistar rat. Material & Method: Experimental study with post-test only control group design. The present  study was conducted on 30 Wistar male rats aged 10 – 12 weeks grouped into 5 groups. Group I was the normal/sham operation group (KN), group II was left testicular torsion for 4 hours group and followed  by manual detorsion  (K1), group III was left testicular torsion for 10 hours group and followed  by manual detorsion (K2),  group IV was left testicular torsion for 4 hours group and given dexamethasone 10 mg/kg body weight subcutaneously 30 minutes before manual etorsion (D1), and group V was left testicular torsion for 10 hours group and  given dexamethasone 10 mg/kg body weight subcutaneously 30 minutes before manual detorsion. All rats had left orchidectomy 4 hours after detorsion. The number of spermatogonium and sertoli cells were counted in histological seminiferous tubular testis that have obtained Haematoxylin Eosin staining. Data were analyzed by ANNOVA followed by Post Hoc Tukey for spermatogonium and Kruskal Wallis followed by Mann Whitney test for sertoli cell. Differences were considered significant at p <0.05. Results: There was significant difference in the mean number of spermatogonium between K1 & D1 group. Otherwise, there was no significant difference in the mean number of spermatogonium between K2 & D2. There was significant difference in the mean number of Sertoli cells between K1 & D1 group, likewise that between K2 & D2 group. Conclusion: These results suggest that dexamethasone has protective effect in spermatogonium and sertoli cell in testicular torsion for 4 hours.

scholarly journals Steatocrit Value in New-Born Babies

2018 ◽  
Vol 35 (7-8) ◽  
pp. 190-3
Author(s):  
Johnwan Usman ◽  
Irfan Abdullah ◽  
Muhazar Muhazar ◽  
Atan Baas Sinuhaji ◽  
A. H. Sutanto
Keyword(s):  
Body Weight ◽  
Breast Milk ◽  
Prospective Study ◽  
The Body ◽  
Milk Formula ◽  
Preterm Newborn ◽  
Formula Milk ◽  
Diet Patterns ◽  
Significant Difference ◽  
A Prospective Study

A prospective study on steatocrit value in full-term or preterm newborn babies of~ 2 days of age in Dr. Pimgadi Hospital, Medan is reported. This study was conducted from December 7, 1992, to February 7, 1993; there were 72 newborn babies (37 males and 35 females). The body weight was> 2500 gin 60 babies and s. 2500 gin 12 babies. The median steatocrit value in babies with body weight of> 2500 g was 9%, and it was 32% in babies less than 2500 g of body weight. The proportion of babies with > 25% steatocrit value was larger in babies less than 2500 g than that in 2500 g by the diet patterns of breast milk, breast milk and milk formula, milk formula. The proportion of babies with < 25% steatocrit value was higher in babies with body weight of< 2500 g than that in babies > 2500 g for those who had either breast milk, breast milk and milk formula or milk formula. There was significant difference (p<0,05) in the steatocrit levels between babies with the body weight of > 2500 g and those who had body weight of ≤ 2500 g.

The effect of body weight at calving on milk production and reproductive performance of Friesian × Zebu heifers

1987 ◽  
Vol 45 (3) ◽  
pp. 325-333 ◽  
Author(s):  
F. Deresz ◽  
C. M. Jaume ◽  
M. R. de Carvalho ◽  
C. A. González
Keyword(s):  
Body Weight ◽  
Post Partum ◽  
Live Weight ◽  
Grass Silage ◽  
Holstein Friesian ◽  
Significant Difference ◽  
Total Milk ◽  
Bean Meal ◽  
The Mean ◽  
Soya Bean Meal

ABSTRACTTwenty-six pregnant Holstein-Friesian × zebu heifers, arranged in pairs according to age, body weight, expected calving date and amount of zebu breeding, were allocated at random to two nutritional regimens during the last 12 weeks before calving. If was planned that the animals in treatment A should calve at a pre-calving live weight of 480 kg and those in treatment B should calve at 380 kg. The diet consisted of maize silage or elephant grass silage, soya-bean meal and minerals. During the first 21 days of the post-partum period both groups were given 6 kg concentrate per head daily. After this period, the feeding level was adjusted every 14 days according to the current milk yield. The mean total milk yields were 2132 kg and 1283 kg (P < 0·05) and the lengths of lactation were 239 days and 156 days (P < 0·01) for cows in treatments A and B, respectively. There was no statistically significant difference between treatments in the intervals from calving to first heat or calving to conception.

The effects of implanting prepuberal dairy heifers with anabolic steroids on live-weight gain, blood and urine composition and milk yield

1979 ◽  
Vol 93 (2) ◽  
pp. 321-327 ◽  
Author(s):  
W. Little ◽  
R. M. Kay ◽  
D. J. Harwood ◽  
R. J. Heitzman
Keyword(s):  
Body Weight ◽  
Anabolic Steroids ◽  
Live Weight ◽  
Feed Conversion ◽  
Trenbolone Acetate ◽  
Dairy Heifers ◽  
Significant Difference ◽  
Weight Gains ◽  
Urine Composition ◽  
The Mean

SUMMARYTwenty-seven British Friesian heifer calves were housed as a group but fed individually barley-lucerne pellets according to a scale related to body weight. At 16 weeks and again at 31 weeks of age nine calves were implanted subcutaneously at the base of the ear with 300 mg trenbolone acetate (group T), nine calves were similarly implanted with 140 mg trenbolone acetate and 20 mg oestradiol-17/? (group TE) and the remaining nine calves were sham implanted (group C).As a result of increased feed conversion ratios, body-weight gains were significantly greater in group T (0–80 kg/day) and group TE (0–87 kg/day) than in group C (0–72 kg/ day) during the 15 weeks following the second implant, but there was no significant difference between groups following the first implant.Following both implants in groups T and TE the mean concentrations of urea and albumin in serum decreased, and that of globulin increased. The mean urea: creatinine ratio in the urine of animals in groups T and TE relative to that in group C also decreased.The heifers were served by an Aberdeen Angus bull at the first and, when they occurred, subsequent oestruses. Following calving the mean milk yields in the first lactation in group T (641 kg in 96 days) and group TE (1993 in 212 days) was considerably lower than in group C (3636 kg in 293 days). The udder size in both groups of animals treated with the anabolic steroids was markedly reduced. It is concluded that despite an improvement in feed conversion ratios and body-weight gains, trenbolone acetate should not be administered to prepuberal heifers which will be retained for breeding and milk production.

scholarly journals Comparing Therapeutic Efficacy and Safety of Epoetin Beta and Epoetin Alfa in the Treatment of Anemia in End-Stage Renal Disease Hemodialysis Patients

2018 ◽  
Vol 48 (4) ◽  
pp. 251-259 ◽  
Author(s):  
Jalal Azmandian ◽  
Mohammad Reza Abbasi ◽  
Vahid Pourfarziani ◽  
Amir Ahmad Nasiri ◽  
Shahrzad Ossareh ◽  
...  
Keyword(s):  
Body Weight ◽  
Hemodialysis Patients ◽  
Phase Iii ◽  
Efficacy And Safety ◽  
Epoetin Alfa ◽  
Double Blind ◽  
Epoetin Beta ◽  
Significant Difference ◽  
The Mean ◽  
Stage Renal Disease

Background: Anemia is one of the most prevalent complications in patients with chronic kidney disease, which is believed to be caused by the insufficient synthesis of erythropoietin by the kidney. This phase III study aimed to compare the efficacy and safety of CinnaPoietin® (epoetin beta, CinnaGen) with Eprex® (epoetin alfa, Janssen Cilag) in the treatment of anemia in ESRD hemodialysis patients. Methods: In this randomized, active-controlled, double-blind, parallel, and non-inferiority trial, patients were randomized to receive either CinnaPoietin® or Eprex® for a 26-week period. The primary endpoints of this study were to assess the mean hemoglobin (Hb) change during the last 4 weeks of treatment from baseline along with the evaluation of the mean weekly epoetin dosage per kilogram of body weight that was necessary to maintain the Hb level within 10–12 g/dL during the last 4 weeks of treatment. As the secondary objective, safety was assessed along with other efficacy endpoints. Results: A total of 156 patients were included in this clinical trial. There was no statistically significant difference between treatment groups regarding the mean Hb change (p = 0.21). In addition, the mean weekly epoetin dosage per kg of body weight for maintaining the Hb level within 10–12 g/dL showed no statistically significant difference between treatment arms (p = 0.63). Moreover, both products had comparable safety profiles. However, the incidence of Hb levels above 13 g/dL was significantly lower in the CinnaPoietin® group. Conclusion: CinnaPoietin® was proved to be non-inferior to Eprex® in the treatment of anemia in ESRD hemodialysis patients. The trial was registered in Clinicaltrials.gov (NCT03408639).

scholarly journals Effect of supplemented dietary protein on certain haematological values and meat yield characteristics of broiler birds

1970 ◽  
Vol 2 (2) ◽  
pp. 121-123 ◽  
Author(s):  
MS Alam ◽  
N Ahmad ◽  
MA Miah ◽  
R Islam
Keyword(s):  
Body Weight ◽  
Dietary Protein ◽  
Body Weight Gain ◽  
The Body ◽  
Meat Yield ◽  
Haematological Values ◽  
Significant Difference ◽  
The Mean ◽  
Group B ◽  
Different Levels

The effect of different levels of supplemented dietary protein on body weight, certain haematological values and meat yield characteristics in 20 "Shaver Star Bro" broilers was studied during the period from 02 March to 12 April 2002. The broilers were randomly assigned to four equal groups (A to D) each consisting of 5 birds. Group A was considered as control, fed only with commercial ration and other three groups were treated with extra dietary protein supplement @ 5%, 10% and 15% as group B, C and D respectively. Increased body weight was recorded in group B and the body weight decreases as the level of protein increased from 5% to 10% and 15% and the decrease was linear. No differences in haematological values were observed among the groups but the TEC varied significantly (p < 0.05). The mean weight of breast meat, drum stick meat varied significantly (p < 0.01). The shank weight varied significantly (p < 0.05) but there was no significant difference among the mean weight of thigh meat and wing meat corresponding to the different levels of supplemented dietary protein. It can be concluded that 5% supplemented dietary protein with commercial ration gives better result in respect to body weight gain, haematological values and meat yield characteristics.Key words: dietary protein; haematological values; meat yield; broiler birdsdoi: 10.3329/bjvm.v2i2.2543Bangl. J. Vet. Med. (2004). 2 (2): 121-123

EFFECTS OF TESTOSTERONE PROPIONATE TREATMENT OF NEONATALLY OVARIECTOMIZED RATS ON GROWTH AND SUBSEQUENT RESPONSIVENESS TO OESTROGEN

1976 ◽  
Vol 82 (3) ◽  
pp. 652-660 ◽  
Author(s):  
M. F. Tarttelin ◽  
J. E. Shryne ◽  
R. A. Gorski
Keyword(s):  
Body Weight ◽  
Testosterone Propionate ◽  
Neonatal Period ◽  
Specific Effect ◽  
Ovariectomized Rats ◽  
Inhibitory Effects ◽  
Androgen Treatment ◽  
Ovx Rats ◽  
Significant Difference ◽  
Oestradiol Benzoate

ABSTRACT There was no significant difference in body weight between neonatally ovariectomized (OvX) rats whether given oil treatment or 90 μg testosterone propionate (TP) on day 3, when examined up to 23 weeks of age. When these two animals were injected with oestradiol benzoate (3 μg/day for 2 weeks), the neonatally OvX TP treated rats showed a significantly smaller depression in body weight than did the control neonatally OxX rats. Measurement of food intake also showed that TP treated rats responded significantly less to the depressant effects of oestrogen than did the controls. These data are consistent with the hypothesis that the ovary does restrain body weight in TP rats but that androgen treatment in the neonatal period may not have a specific effect on growth but may alter the sensitivity of growth regulating processes to the inhibitory effects of oestrogen.

scholarly journals A Study on Somatotype Profiles of the Players in Turkish Bocce National Team

2018 ◽  
Vol 6 (2) ◽  
pp. 28
Author(s):  
Nebahat Eler ◽  
Serdar Eler
Keyword(s):  
Body Weight ◽  
Body Fat ◽  
Body Fat Percentage ◽  
Muscular Force ◽  
Fat Percentage ◽  
Tennis Players ◽  
National Team ◽  
Significant Difference ◽  
Package Program ◽  
The Mean

The aim of this study is to determine the differences between the somatotype profiles and inter-disciplinary somatotype profiles of the Turkish Bocce National Team players. In this study, the mean age of the Turkish Men’s Bocce National Team (n-32) was determined as 21,75±2,35 (years), mean height was 177,62±1,03 (cm), mean body weight was 70,75±0,70 (kg), mean Body Mass Index (BMI) was 22,31±1,06 kg/m2, mean body fat percentage was 16,05±1%. The mean age of the Turkish Women’s Bocce National Team (n-21) was 21,76±2,12 (years), mean height was 165,33±4,24 (cm), mean body weight 55,14±6,36 (kg), mean BMI was 23,22±1,06 kg/m2 mean body fat percentage was 16,05±1%. The Heath-Carter method was used in determining the somatotype profiles of the players. the The statistical analyses in the study were made by using the SPSS 20.0 package program. Somatotype profile in men was determined endomorphic 3,21±0,33; mesomorph 5,04±1,11; ectomorphic 2,20±0,18 as mesomorphic-endomorphic; in women, endomorphic 3,33±1,42; mesomorph 5,08±0,26; ectomorphic 2,07±0,09 as mesomorphic-endomorphic. In this study, the somatotype profiles of the Turkish Bocce National Team players were determined, and a statistically significant difference was detected between the volo and petanque-raffa disciplines in men and women (p<0,05). It is believed that this difference stems from the physical performance requiring more muscular force in volo discipline than the petanque and raffa disciplines. In this study, the somatotype components are similar in tennis players in volo men group and the archers, judo players and Water polo players of the other groups (Men-women petanque and raffa group, Women volo group).

scholarly journals Inactivation of Different Salmonella enteriditis Phage Types and Safety and Efficacy of Inactivated Products in Chicken

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
A. Akhtar ◽  
M. Hair-Bejo ◽  
Elawad A. Hussein ◽  
Zunita Zakaria
Keyword(s):  
Body Weight ◽  
Clinical Signs ◽  
The Body ◽  
Safety And Efficacy ◽  
Phage Types ◽  
Significant Difference ◽  
Salmonella Enteriditis ◽  
Gross Lesions ◽  
The Mean ◽  
Different Tissues

This study was conducted to inactivate Salmonella enteriditis phage types (SE pt) and to determine the safety and efficacy of inactivated SE pt in chickens. SE pt 1, 3A, 6A, 7, and 35 were inactivated and inoculated (0.20 mL) in 124 chickens divided into 6 groups (CV1, CV3A, CV6A, CV7, CV35, and CV0 as a control). Sampling was conducted on day 14 after inoculation (pi). Eight chickens from each group were separated on day 14 pi for oral challenge with 0.20 mL/chicken (1010 cfu/mL) SE pt 6A and designated CV1C, CV3AC, CV6AC, CV7C, CV35C, and CV0C as control chickens. On days 7 and 14 postchallenge (pc), 4 chickens from every group were sacrificed for sampling. There was no significant difference in the body weight between different groups. In challenged groups, there was no significant association between different tissues and isolation of Salmonella on days 7 and 14 pc. There was significance (p < 0.05) in isolation of Salmonella when CV0C group was compared with other challenged groups. Significance was not observed between different tissues with respect to induction of microscopic changes. Significance was not observed between day 7 pc and day 14 pc with respect to scoring of lesions induced. Clinical signs and gross lesions were also recorded. ELISA was applied. Only in CV3AC group, the mean antibody titer was 1359 on day 14 pc. The conclusion was that inactivated SE pt 3A and 6A were safe and efficacious for protection against Salmonella enteriditis infection in chickens.

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