scholarly journals Skeletal involvement in Gaucher disease: extent of bone disease, splenic volume, and quality of life

2021 ◽  
Vol 54 (2) ◽  
pp. 71-76
Author(s):  
Ricardo Andrade Fernandes de Mello ◽  
Melissa Bosi Nonato Mello ◽  
Laís Bastos Pessanha ◽  
Ana Paula Alves Fonseca
Keyword(s):  
Quality Of Life ◽  
Linear Relationship ◽  
Bone Disease ◽  
Gaucher Disease ◽  
Disease Extent ◽  
Cross Sectional ◽  
Splenic Volume ◽  
Life Score ◽  
Skeletal Involvement

Abstract Objective: To investigate the correlations among the extent of bone involvement, splenic volume, and quality of life in patients with Gaucher disease. Materials and Methods: This was a descriptive, prospective cross-sectional study of 18 patients with Gaucher disease who underwent 3-T magnetic resonance imaging of both femurs and the lumbar spine. Semiquantitative analyses were performed on the basis of the bone marrow burden (BMB) score. We looked for linear relationships among the variables splenic volume, quality of life score, and BMB score. Results: We identified a linear relationship between the BMB scores and splenic volume. The quality of life score showed no statistically significant relationship with splenic volume or the BMB score. Conclusion: The linear relationship between the BMB score and the splenic volume indicates that the extent of bone disease is greater in individuals with splenomegaly. No correlation was found between the BMB and quality of life scores, illustrating the insidious and silent progression of Gaucher disease.

scholarly journals Quality of life and its associated factors among epileptic patients attending public hospitals in North Wollo Zone, Northeast Ethiopia: A cross-sectional study

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247336
Author(s):  
Ayelign Mengesha Kassie ◽  
Biruk Beletew Abate ◽  
Mesfin Wudu Kassaw ◽  
Addisu Getie ◽  
Adam Wondmieneh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Public Hospitals ◽  
Evil Spirit ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Life Score ◽  
Epileptic Patients ◽  
Related Quality ◽  
Health Related

Background Epilepsy is thought to be caused by witchcraft, evil spirit, and God’s punishment for sins in many developing countries. As a result, people with epilepsy and their families usually suffer from stigma, discrimination, depression, and other psychiatric problems. Thus, this study aimed to assess the quality of life and its associated factors among epileptic patients attending public hospitals in North Wollo Zone, Northeast Ethiopia. Methods An institution-based cross-sectional study design was employed in this study. A simple random sampling technique was utilized. Health-related quality of life was measured based on the total score of the Quality of Life in Epilepsy Inventory (QOLIE-31) instrument. Data were entered into Epi-data 3.1 statistical package and exported to SPSS Version 20 for further analysis. Linear regression models were used to assess the relationship between quality of life and the independent variables. Statistically significant values were declared at a P-value of < 0.05. Results A total of 395 patients participated in the study making the response rate 98.5%. The mean age of the participants was 32.39 ±10.71 years. More than half, 199 (50.4%) of epileptic patients had an overall weighted average health related quality of life score of mean and above. Male sex (B = 4.34, 95%CI, 0.41, 8.27, P = 0.03), higher educational status (B = 7.18, 95%CI, 1.39, 13.00, P = 0.015) and age at onset of epilepsy (B = 0.237, 95%CI, 0.02, 0.45, P = 0.035) were associated with increased health related quality of life score. On the other hand, family history of epilepsy (B = -4.78, 95%CI,-9.24,-0.33, P = 0.035), uncontrolled seizure (B = -11.08, 95%CI,-15.11,-7.05, P < 0.001), more than 5 pre-treatment number of seizures (B = -4.86, 95%CI,-8.91,-0.81, P = 0.019), poor drug adherence (B = -11.65, 95%CI,-16.06,-7.23, P < 0.001), having moderate (B = -4.526, 95%CI,-8.59,-0.46, P = 0.029) to sever (B = -12.84, 95%CI,-18.30,-7.37, P < 0.001) anxiety and depression, believing that epilepsy is caused by evil spirit (B = -7.04, 95%CI,-11.46,-2.61, P = 0.002), drinking alcohol (B = -5.42, 95%CI,-10.72,-0.13, P = 0.045), and having other co-morbidities (B = -9.35, 95%CI,-14.35,-4.36, P < 0.001) were significantly negatively associated with the health related quality of life score among epileptic patients. Conclusions Only around half of the epileptic patients have a good health-related quality of life. In addition, multiple variables including family history, uncontrolled seizure, and poor drug adherence were associated with quality of life among epileptic patients. Hence, targeting these variables in epilepsy management is recommended.

scholarly journals A cross-sectional study analysing the association between habitual physical activity levels and quality of life in adults with asthma

2015 ◽  
Vol 7 (1) ◽  
pp. 29-41
Author(s):  
ADEEL NAZIR AHMAD ◽  
KIMBERLEY L. EDWARDS
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Positive Association ◽  
Habitual Physical Activity ◽  
Activity Levels ◽  
Cross Sectional ◽  
Physical Activity Guidelines ◽  
Life Score ◽  
Physical Activity Levels

Background: People with asthma believe their condition prevents them from undertaking physical activity. The objective was to determine the association between habitual physical activity levels and the quality of life in adults with asthma and meeting the physical activity guidelines. Material/Methods: A cross-sectional survey of adults (aged >18) with asthma was conducted in three general practices in Nottingham, UK (n = 128). A self-reported short form International Physical Activity Questionnaire, mini Asthma Quality of Life Questionnaire and a demographic questionnaire (age, gender, ethnicity and BMI) were used to collect data. Physical activity was provided in minutes for different activities to enable the habitual weekly MET-minutes to be calculated, and the quality of life score was determined. Results: Among 128 respondents, 22% met the physical activity guidelines. Mostly younger, white, male, normal weight participants had higher physical activity levels and better asthma quality of life. Mean total asthma quality of life score was 4.5. Linear regression modelling showed a positive association between the total physical activity and the quality of life score (p < 0.001); thus higher physical activity levels were associated with less/no asthma quality of life impairment (higher score). Conclusions: The majority of asthmatics in this study had low physical activity levels, did not meet the recommended physical activity guidelines and had impaired quality of life. A strong positive association between physical activity and asthma quality of life supports the view that adults with asthma should be encouraged to be sufficiently physically active, which could be associated with a better asthma related quality of life.

scholarly journals Ảnh hưởng của tình trạng dinh dưỡng lên chất lượng sống của bệnh nhân ung thư được điều trị hóa chất tại khoa Ung bướu Bệnh viện trường Đại học Y Dược Huế

2020 ◽  
Author(s):  
Thị Hồng Chuyên Nguyễn
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Chi Square ◽  
Cross Sectional ◽  
Life Score ◽  
Relationship Of ◽  
The Relationship

ASSESSING THE RELATIONSHIP OF NUTRITIONAL STATUS TO THE QUALITY OF LIFE OF CANCER PATIENTS RECEIVING CHEMOTHERAPY AT THE ONCOLOGY DEPARTMENT OF HUE COLLEGE OF MEDICINE AND PHARMACY Background: Cancer is the second leading cause of death globally as well as in Vietnam. Chemotherapy is a systemic treatment with chemical drugs. Chemotherapy often causes many problems related to physical, mental and toxicity, which have an effect on the quality of life and nutritional status of patients. While malnutrition has been shown to be common in cancer patients, its impacts on the patient's quality of life have not been adequately studied, especially in Vietnam. Objective: To evaluate the quality of life of cancer patients receiving chemotherapy. To determine the relationship of nutritional status to the quality of life in these patients. Methods: A cross-sectional study was conducted on 82 patients with cancer during a chemotherapytreatment at the Department of Oncology, Hue College of Medicine and Pharmacy from February 2018 to February 2019. Assessing the quality of life by the Quality of Life Questionnaire of the European Organizationfor Research and Treatment of Cancer (EORTC QLQ-C30). Descriptive statistics and test Chi-square and Fisher exact were performed to analyze the quality of life parameters and the relationship between nutritional status and quality of life. Results: A total of 82 subjects were included in this study, 51 subjects (62.20%) were males and 31 subjects (37.80%) were females, the mean age was 58.98 ± 12.52. The most common type of cancer is gastrointestinal cancer (37.80%), the highest stage of cancer is stage 4 (56.10%), symptomatic chemotherapy accounts for the highest rate with 53.70% and the average number of chemotherapy cycles is 4.00 ± 3.68. The study shows that the meanglobal health status is 50.00 ± 16.89, the best quality of life score is in the field of cognitive function with 83.33 points, the worst quality of life score is in the symptoms field of insomnia and in the financial difficulties with 66.67 points. Results from Chi-square and Fisher Exact analysis test revealed a statistically significant association between the risk of malnutrition according to SGA classification and the role functioning offunctional scales (p <0.05). Conclusions: The quality of life of cancer patients is generally good. The nutritional status affects the quality of life in the field of role function. Keywords: Quality of life, cancer, chemotherapy.

scholarly journals Cost-Utility Analysis of Percutaneous and Surgery Methods in Extraction of Cardiac Leads Infection

2021 ◽  
Author(s):  
zinab shaker ◽  
Mohsen Barooni ◽  
Asma Saber Mahani ◽  
Zohreh Shaker
Keyword(s):  
Quality Of Life ◽  
Cardiovascular Diseases ◽  
Cost Utility ◽  
Utility Analysis ◽  
Cross Sectional ◽  
Life Score ◽  
Pacemaker Leads ◽  
The Cost ◽  
Surgical Cost

Abstract Introduction: Cardiovascular diseases are currently major concern in the world and It is expected that Until 2030, 7 out of 10 deaths in world will be related to cardiovascular diseases. Despite the increase in Pasemaker and ICD implants in recent years, the complications of this devices are increasing. One of the most important complications is the pulsating lead infection. The purpose of this study was to analyze the cost-effectiveness of percutaneous and surgical method in extracting pacemaker leads with Qaly index.Methods: In this cross-sectional article (descriptive-analytical) using the Markov model, for compare the two methods of percutaneous and surgery for infectious lead. Sampling was census and ( sample size for percutaneous included 57 people) and information about utility was extracted by the SAQ questionnaire. A systematic review was performed to calculate utility of the surgical Cost from the perspective of the service provider. data analysis by SPSS software, and TreeAge software was used for Markov modeland and sensitivity analysis .Results: Changes in quality of life score in both intervention were incremental and significant and intervention is the only effective factor in changes in quality of life score (P <0.05). The ICER was 5470.44$.Conclusion: The results of the study show that utility and cost of surgery are higher than the percutaneous method.Sensitivity analysis shows If the cost of surgery increases more than 806.52$ (discount rate of 0.06), the percutaneous method dominates the surgery method.

EVALUATION OF THE QUALITY OF LIFE OF PATIENTS WITH SYPHILIS TREATMENT AT THE CENTRAL HOSPITAL OF DERMATOLOGY

2021 ◽  
Vol 62 (5) ◽  
Author(s):  
Hoang Van Khoan ◽  
Phuong Quynh Hoa
Keyword(s):  
Quality Of Life ◽  
Poor Quality ◽  
Measurement Tool ◽  
National Hospital ◽  
Cross Sectional ◽  
Life Score ◽  
Results Of Treatment ◽  
Life Measurement ◽  
Syphilis Treatment

Quality of life is a widely used concept to measure the results of treatment of patients in general and patients with genital warts in particular. To provide data on the quality of life of warts patientstreated at the National Hospital of Dermatology, as a basis for improving the quality of treatment, we conducted this study to: Describe the quality of life. Survival of patients with warts treated at the National Hospital of Dermatology. This is a cross-sectional descriptive study. Information was collected through interviews with 210 patients with warts treated at the National Hospital of Dermatology (December 6, 2020) using the QE-5D-5L quality of life measurement tool kit. Research results show that the quality of life is quite and good accounted for 57.6% with a quality of life score of 0.9910 ± 0.058, an average quality of life is quite good at 36.2% with a quality of life score of 0.729 ± 0.048, mean quality of life is 2.9%with quality of life score of 0.533 ± 0.043, patients with poor quality of life account for 3.3% of quality of life, which is 0.288 ± 0.101.

scholarly journals Correlation Between Stress and Quality of Life Experienced by Caregivers: Perception of a Group of Healthcare Professionals

2017 ◽  
Vol 11 (1) ◽  
pp. 135-141 ◽  
Author(s):  
Bhárbara Karolline Rodrigues Silva ◽  
Fernando Rodrigues Peixoto Quaresma ◽  
Erika da Silva Maciel ◽  
Francisco Winter dos Santos Figueiredo ◽  
Jonathan Souza Sarraf ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Health ◽  
Human Beings ◽  
Total Quality ◽  
Cross Sectional ◽  
Significance Level ◽  
Life Score ◽  
Health Domain ◽  
Physical Health Domain

Aim:This study aims to evaluate the relationship between perceived level of stress and quality of life of professionals working in Prompt Service Units in the city of Palmas, Tocantins.Methods:A cross-sectional study was performed among 164 professionals from Prompt Service Units. Stress levels were evaluated using the Perceived Stress Scale. The WHOQOL-bref was used to evaluate the perception of quality of life. Quantitative variables distribution was evaluated using Shapiro-Wilk's test. For the analyses of correlations among perceived level of stress, total quality of life score, and the physical health domain of the WHOQOL-bref, Pearson's correlation test was applied. The significance level adopted for this trial was 95%. The study was approved by the Committee of Ethics in Research with Human Beings.Results:When assessing the perceived level of stress with the total quality of life score, there was no significant correlation between those variables. However, there was an association between the perceived level of stress and the physical health domain of quality of life.Conclusion:Perceived quality of life was correlated with the physical health domain, and this result reinforces the importance of the facets that make up this area.

scholarly journals Surveing the Quality of life in Employees health centers of Yazd Province in 2011

2020 ◽  
Author(s):  
Seyed Saeed Mazloomi Mahmodabad ◽  
Mohammad Reza Aalaei ◽  
RaZyeh Zolghadr ◽  
Aghdas Hajirezaei ◽  
Tayebeh Nik ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Data Collection ◽  
Work Experience ◽  
Cross Sectional Study ◽  
Health Centers ◽  
Cross Sectional ◽  
Climate Conditions ◽  
Life Score ◽  
Life Styles

Introduction: Quality of life is a subjective and multidimensional concept that in recent years has been noticeable by researcher due to multilateral widespread of technology and industrialization process. Quality of life, was  is individuals understanding of their status in the context of physical, mental and social impacts and to indicate the status of a resident in a country or region. The purpose of this study was determination the quality of life in employees health centers of Yazd province about healthy life styles in 2011. Methods : This research was a cross - sectional study in which 501 staff employed  in 12 central areas of health centers of Yazd  as census method were enrolled . Data collection tool was WHO Quality of Life-BREF questionnaire (WHOQOL-BREF) including 26 questions,). After  data collection , it was analyzed  by using SPSS software as well as statistical t-test and ANOVA. Results: The results shown that the employees health centers of Yazd province were acquired 67.9% of the quality of life score. The way in which the dimensions of physical, psychological, social relationships and environment were obtained 72.9, 65.5, 70.2 and 63.15 ​​percent from the maximum score; Respectively. The quality of life score based on age, gender, type of employment, work experience and climate conditions were significant (p≤ 0.05). Conclusions: Therefore it was suggested to improve the quality of life of employees health centers, officials with proper planning includes considering educational , cultural, recreational and sport programs ,, providing healthy nutrition, installing motivation and responsibility in them as well as paying  proper salary and benefits, take effective steps in this way.

scholarly journals mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis

2017 ◽  
Vol 3 (4) ◽  
pp. 00084-2017 ◽  
Author(s):  
Kaisa Rajala ◽  
Juho T. Lehto ◽  
Eva Sutinen ◽  
Hannu Kautiainen ◽  
Marjukka Myllärniemi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Palliative Care ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Linear Relationship ◽  
Real Life ◽  
Symptom Burden ◽  
Cross Sectional ◽  
Edmonton Symptom Assessment Scale

This study was undertaken to investigate idiopathic pulmonary fibrosis (IPF) patients' health-related quality of life (HRQoL) and symptoms in a real-life cross-sectional study. Our secondary aim was to create a simple identification method for patients with increased need for palliative care by studying the relationship between modified Medical Research Council (mMRC) dyspnoea scale, HRQoL and symptoms.We sent a self-rating HRQoL questionnaire (RAND-36) and modified Edmonton Symptom Assessment Scale (ESAS) to 300 IPF patients; 84% of the patients responded to these questionnaires.The most prevalent (>80%) symptoms were tiredness, breathlessness, cough and pain in movement. An increasing mMRC score showed a linear relationship (p<0.001) to impaired HRQoL in all dimensions of RAND-36 and the severity of all symptoms in ESAS. Dimensions of RAND-36 fell below general population reference values in patients with mMRC score ≥2. The intensity of pain in movement (p<0.001) and at rest (p=0.041), and the prevalence of chest pain (p<0.001) had a positive linear relationship to increased mMRC score.An increasing mMRC score reflects impaired HRQoL and a high symptom burden. In clinical practice, the mMRC scale could be used for screening and identification of IPF patients with increased need for palliative care.

Assessment of the quality of life of breast cancer patients after one year of treatment

2021 ◽  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Related Factors ◽  
Cross Sectional ◽  
Life Score ◽  
One Year

Introduction: Breast cancer is the most commonly diagnosed malignancy and the leading cause of death among women worldwide. The incidence of breast cancer is on the rise in developing countries. Breast cancer patients not only experience physical pain from treatment but may also face mental crises, impaired social function, and impaired quality of life. However, there are not many studies on the quality of life (QoL) of post - treatment breast cancer patients. Therefore, we carried out the study “assessment the quality of life of breast cancer patients after one year of treatment” with aims to evaluate the quality of life of breast cancer patients after one year of treatment using the scales EQ-5D-5L and QLQ-BR23 and to find out related factors to the quality of life of these subjects. Methods: A cross - sectional study was conducted on 100 breast cancer patients after one year of treatment at the Hue University of Medicine and Pharmacy Hospital to examine the quality of life using the scales EQ-5D-5L and QLQ-BR23 and to detect the associated factors. Results: The mean quality of life score of breast cancer patients after one year of treatment on the EQ- 5D-5L scale was 0.6436 ± 0.2098. By QLQ-BR23, the quality of life score on function was 74.75 ± 20.78 while the score on symptoms was 28.80 ± 12.79. The quality of life from both scales was found to be statistically significant related to social work participation, self - reported health, risk of depression, anxiety, and stress. Conclusions: The quality of life of breast cancer patients in the study was at a moderate level. This suggests more supports to be done continuously after long - term post - diagnosing especially psychological and social aspects for these subjects.

scholarly journals Flatfoot decreases school functioning among children < 11 years of age

2018 ◽  
Vol 37 (1) ◽  
pp. 50 ◽  
Author(s):  
Yuke Damayanti ◽  
Panji Fortuna Hadisoemarto ◽  
Irma Ruslina Defi
Keyword(s):  
Quality Of Life ◽  
School Functioning ◽  
Total Quality ◽  
Cross Sectional ◽  
Life Score ◽  
Domain Specific ◽  
Significant Difference ◽  
Cross Sectional Design ◽  
Made In

Background <br />Flatfoot is a musculoskeletal abnormality commonly found in children that could result in a reduction of quality of life because of its related symptoms and functional abnormalities. This study aimed to determine the association between flatfoot and the quality of life among children 5-18 years of age. <br /><br />Methods <br />A cross sectional design was used in this study of children aged 5-18 years. The diagnosis of flatfoot was made in accordance with the Chippaux-Smirak Index classification, whereas general and domain-specific quality of life were measured using the Indonesian version of PedsQL™ that has been previously validated. Mann Whitney test was used to compare quality of life between children with flatfoot and normal feet, along with other variables that potentially may influence a child’s quality of life. <br /><br />Results <br />A total of 79 out of 120 subjects was used to analyze the data. There was a statistically significant difference in the quality of life score in the school functioning domain between children with flatfoot (64.46 ±18.22) and those with normal feet (75.90 ±17.29) in children &lt;11 years of age (p=0.029). Apart from this, the study did not find any statistically significant differences in the total quality of life score or in other quality of life domains between the two groups. <br /><br />Conclusions <br />Flatfoot significantly decreases children’s quality of life in the school functioning domain. Early detection and correction of flatfoot may be necessary to improve the educational attainment of children suffering from this condition.

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