scholarly journals Factors associated with abnormalities of the cytopathological uterine cervix test in South of Brazil

2017 ◽  
Vol 17 (4) ◽  
pp. 637-643
Author(s):  
Willian Augusto de Melo ◽  
Sandra Marisa Pelloso ◽  
Aline Alvarenga ◽  
Maria Dalva de Barros Carvalho
Keyword(s):  
Uterine Cervix ◽  
Education Level ◽  
Fisher Exact Test ◽  
Low Grade ◽  
Cervical Lesions ◽  
Significance Level ◽  
Exact Test ◽  
White Ethnicity ◽  
Factors Associated ◽  
South Of Brazil

Abstract Objectives: to identify factors associated with abnormal cytopathological test uterine cervix. Methods: it is a analytical study with the participation of 390 women who presented abnormal cytopathological from a city in the state of Paraná in 2012. They were randomly selected through sampling plan. Sociodemographic information such as age, marital status, education level and ethnicity were considered independent variables while the high or low-grade cytological lesions as dependent variable. We analyzed the data statistically by Yates Corrected test, Fisher exact test and measures of association by odds ratio. For all analyzes was considered significance level of 5% and 95% confidence interval. Results: the mean age was 38.8 years, 72.9% were married or common-law marriage, 49.7% with low education level and 87.4% race/color white. HPV contamination was detected in 49.7% of women and high-grade cytological lesions in 18.2%. The low educa-tional level (95%OR=4.07) and non-white ethnicity (95%OR=2.22) were strongly associated with the development to cervical lesions (p<0.05). Conclusions: sociodemoghaphic characteristics were crucial to high-risk lesions and development of cervical cancer, especially in women with low educational level and race/color black or brown. These results confirm the persistence of diseases related to preventable and avoidable causes in the country.

scholarly journals Migraine as a risk factor associated with hypertensive disorders of pregnancy

2014 ◽  
pp. 33-38
Author(s):  
Gabriel Braga Diégues Serva ◽  
Leonardo Santos Calvacanti Guerra ◽  
Vilneide Maria Santos Braga Diégues Serva ◽  
Waldmiro Antônio Diégues Serva ◽  
Marcela Patrícia Macêdo Belo ◽  
...  
Keyword(s):  
Fisher Exact Test ◽  
Hypertensive Disorders Of Pregnancy ◽  
Significance Level ◽  
Exact Test ◽  
Factors Associated ◽  
Follow Up Study ◽  
Hypertensive Disorders ◽  
Pregnancy And Postpartum ◽  
Hypertensive Disorders In Pregnancy

Objectives: To identify if the presence of migraine before pregnancy predisposes to hypertensive disorders of pregnancy. Methods: Observational study undertaken from a database of a follow-up study, composed of women consecutively assisted, at the first postnatal week, at IMIP. Its objective was to evaluate the course of migraine during pregnancy and postpartum in women with migraine before pregnancy. The Fisher exact test was used considering the significance level of less than 5%. Results: Of the 686 women, 38.8% were migraine sufferers before pregnancy. 14.3% referred hypertensive disorders of pregnancy. The presence of migraine before pregnancy and to have been submitted to a cesarean section (p<0.001) were factors associated with the presence of hypertensive disorders in pregnancy. Conclusion: Migraine before pregnancy is an associated factor to hypertensive disorders of pregnancy. The diagnosis of migraine should always be taken into consideration during antenatal care, for the prevention of complications.

Characteristics of Physician Relocation Following Hurricane Katrina

2009 ◽  
Vol 95 (1) ◽  
pp. 6-12
Author(s):  
Kusuma Madamala ◽  
Claudia R. Campbell ◽  
Edbert B. Hsu ◽  
Yu-Hsiang Hsieh ◽  
James James
Keyword(s):  
Hurricane Katrina ◽  
Gulf Coast ◽  
General Medicine ◽  
The United States ◽  
Lessons Learned ◽  
Bivariate Analysis ◽  
Fisher Exact Test ◽  
Exact Test ◽  
Factors Associated ◽  
The Impact

ABSTRACT Introduction: On Aug. 29, 2005, Hurricane Katrina made landfall along the Gulf Coast of the United States, resulting in the evacuation of more than 1.5 million people, including nearly 6000 physicians. This article examines the relocation patterns of physicians following the storm, determines the impact that the disaster had on their lives and practices, and identifies lessons learned. Methods: An Internet-based survey was conducted among licensed physicians reporting addresses within Federal Emergency Management Agency-designated disaster zones in Louisiana and Mississippi. Descriptive data analysis was used to describe respondent characteristics. Multivariate logistic regression was performed to identify the factors associated with physician nonreturn to original practice. For those remaining relocated out of state, bivariate analysis with x2 or Fisher exact test was used to determine factors associated with plans to return to original practice. Results: A total of 312 eligible responses were collected. Among disaster zone respondents, 85.6 percent lived in Louisiana and 14.4 percent resided in Mississippi before the hurricane struck. By spring 2006, 75.6 percent (n = 236) of the respondents had returned to their original homes, whereas 24.4 percent (n = 76) remained displaced. Factors associated with nonreturn to original employment included family or general medicine practice (OR 0.42, 95 percent CI 0.17–1.04; P = .059) and severe or complete damage to the workplace (OR 0.24, 95 percent CI 0.13–0.42; P &lt; .001). Conclusions: A sizeable proportion of physicians remain displaced after Hurricane Katrina, along with a lasting decrease in the number of physicians serving in the areas affected by the disaster. Programs designed to address identified physician needs in the aftermath of the storm may give confidence to displaced physicians to return.

scholarly journals Phlebitis associated with peripheral intravenous catheters in adults admitted to hospital in the Western Brazilian Amazon

2016 ◽  
Vol 50 (2) ◽  
pp. 263-271 ◽  
Author(s):  
Sandra Maria Sampaio Enes ◽  
Simone Perufo Opitz ◽  
André Ricardo Maia da Costa de Faro ◽  
Mavilde de Luz Gonçalves Pedreira
Keyword(s):  
Intermittent Infusion ◽  
Brazilian Amazon ◽  
Fisher Exact Test ◽  
Intravenous Therapy ◽  
Chi Square ◽  
Significance Level ◽  
Exact Test ◽  
Dorsal Hand Vein ◽  
Mean Time ◽  
Intravenous Catheters

Abstract OBJECTIVE To identify the presence of phlebitis and the factors that influence the development of this complication in adult patients admitted to hospital in the western Brazilian Amazon. METHOD Exploratory study with a sample of 122 peripheral intravenous catheters inserted in 122 patients in a medical unit. Variables related to the patient and intravenous therapy were analyzed. For the analysis, we used chi-square tests of Pearson and Fisher exact test, with 5% significance level. RESULTS Complication was the main reason for catheter removal (67.2%), phlebitis was the most frequent complication (31.1%). The mean duration of intravenous therapy use was 8.81 days in continuous and intermittent infusion (61.5%), in 20G catheter (39.3%), inserted in the dorsal hand vein arc (36.9 %), with mean time of usage of 68.4 hours. The type of infusion (p=0.044) and the presence of chronic disease (p=0.005) and infection (p=0.007) affected the development of phlebitis. CONCLUSION There was a high frequency of phlebitis in the sample, being influenced by concomitant use of continuous and intermittent infusion of drugs and solutions, and more frequent in patients with chronic diseases and infection.

scholarly journals Diastasis recti abdominis during pregnancy and 12 months after childbirth: prevalence, risk factors and report of lumbopelvic pain

2016 ◽  
Vol 50 (17) ◽  
pp. 1092-1096 ◽  
Author(s):  
Jorun Bakken Sperstad ◽  
Merete Kolberg Tennfjord ◽  
Gunvor Hilde ◽  
Marie Ellström-Engh ◽  
Kari Bø
Keyword(s):  
Risk Factors ◽  
Post Partum ◽  
Fisher Exact Test ◽  
Significance Level ◽  
Exact Test ◽  
Diastasis Recti ◽  
Student’S T ◽  
First Time ◽  
Diastasis Recti Abdominis ◽  
Student’S T Test

Background/aimDiastasis recti abdominis (DRA) is defined as a separation of the 2 muscle bellies of rectus abdominis. To date there is scant knowledge on prevalence, risk factors, and consequences of the condition. The present study aimed to investigate the prevalence of DRA during pregnancy and post partum, presence of possible risk factors, and the occurrence of lumbopelvic pain among women with and without DRA.MethodsThis prospective cohort study followed 300 first-time pregnant women from pregnancy till 12 months post partum. Data were collected by electronic questionnaire and clinical examinations. DRA was defined as a palpated separation of ≥2 fingerbreadths either 4.5 cm above, at or 4.5 cm below the umbilicus. Women with and without DRA were compared with independent samples Student's t-test and χ2/Fisher exact test, and OR with significance level >0.05.ResultsPrevalence of DRA was 33.1%, 60.0%, 45.4%, and 32.6% at gestation week 21, 6 weeks, 6 months and 12 months post partum, respectively. No difference in risk factors was found when comparing women with and without DRA. OR showed a greater likelihood for DRA among women reporting heavy lifting ≥20 times weekly (OR 2.18 95% CI 1.05 to 4.52). There was no difference in reported lumbopelvic pain (p=0.10) in women with and without DRA.ConclusionsPrevalence of mild DRA was high both during pregnancy and after childbirth. Women with and without DRA reported the same amount of lumbopelvic pain 12 months post partum.

scholarly journals Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in Moldavian population

2020 ◽  
Author(s):  
Alexander M. Varzari ◽  
Igor V. Deyneko ◽  
Elena Tudor ◽  
Harald Grallert ◽  
Thomas Illig
Keyword(s):  
Pulmonary Tuberculosis ◽  
Interaction Analysis ◽  
Fisher Exact Test ◽  
Polymorphism Analysis ◽  
Bonferroni Correction ◽  
Significance Level ◽  
Exact Test ◽  
Pulmonary Tb ◽  
Efficient Recognition ◽  
Core Genes

Abstract BACKGROUND Host immunity is essential for efficient recognition and clearance of M. tuberculosis infection. Polymorphisms in genes that regulate immune response have been reported to influence the susceptibility/resistance to pulmonary tuberculosis (TB). Here we evaluated associations between 14 polymorphisms in 12 core genes involved in immune responses and pulmonary TB in Moldavian population, and investigated whether interactions between these and previously analyzed polymorphisms could exist and modulate the risk of pulmonary TB. METHODS Polymorphisms VDR rs7975232, VDR rs1544410, VDR rs2228570, MR1 rs1052632, TLR1 rs5743618, TLR2 rs111200466, TLR10 rs11096957, SLC11A1 rs2276631, IL1B rs1143643, IL10 rs1800896, IFNG rs2430561, TNF rs1800629, IRAK1 rs1059703, and FOXP3 rs2232365 were genotyped in 271 Moldavian pulmonary TB cases and 251 community-matched healthy controls. Associations were tested using Fisher test and logistic regression. Complemented with the data from our previous study (PMID: 30529560), investigation of gene-gene interactions was performed for a total of 43 loci. Significance level was adjusted by the Bonferroni correction. RESULTS Single polymorphism analysis revealed a nominal association between TNF rs1800629 and pulmonary TB (Fisher exact test p-value = 0.01843). Marginal differences between cases and controls were observed for haplotypes in the gene cluster TLR1-TLR6-TLR10 and gene TLR2. In the pairwise interaction analysis, the combination of genotypes TLR6 rs5743810 GA and TLR10 rs11096957 GT was significantly associated with an increased genetic risk of pulmonary TB (OR = 2.48, 95% CI = 1.62–3.85; Fisher exact test p-value = 1.5 × 10− 5, significant after Bonferroni correction). CONCLUSION The TLR6 rs5743810 and TLR10 rs11096957 two-locus interaction confers a significantly higher risk for pulmonary TB and has potential as a novel biomarker for predicting TB susceptibility.

scholarly journals HUBUNGAN KECEMASAN DENGAN KELANCARAN PENGELUARAN ASI PADA IBU POST PARTUM SELAMA DIRAWAT DI RUMAH SAKIT IBU DAN ANAK KASIH IBU MANADO

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Zulfikar Mardjun ◽  
Grace Korompis ◽  
Sefti Rompas
Keyword(s):  
Breast Milk ◽  
Sampling Method ◽  
Post Partum ◽  
Fisher Exact Test ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Exact Test ◽  
Postpartum Mothers ◽  
The Relationship

Abstract : Smooth breastfeeding is influenced by several factors, one of which ispsychological factors, namely anxiety. In general, postpartum mothers often experiencefatigue and mood swings such as anxiety; about themselves and about their new-born baby.This anxiety can affect the smoothness of breastfeeding in post partum mothers. The purposeof this study was to determine the relationship between anxiety and smooth release of breastmilk in post partum mothers while being treated at Mother and Baby Hospital, Kasih IbuManado. The method of this research uses cross sectional research design. The sampleconsisted of 68 respondents with a non probability sampling method with a purposivesampling technique. The results using the Chi-Square did not fulfill the requirements thuscontinued with the Fisher Exact test at the significance level of 95%, obtained by the value ρ -Value 0.001 smaller than the significant value of 0.05. In conclusion, there is a relationshipbetween anxiety and the smooth releasee of breast milk in post partum mothers while beingtreated at Kasih Ibu Hospital.Keywords : Anxiety, Smooth Release of Breast MilkAbstrak : Kelancaran pengeluaran ASI dipengaruhi oleh beberapa faktor, salah satunyafaktor psikologis yaitu kecemasan. Pada umumnya ibu pasca persalinan sering mengalamikelelahan dan perubahan mood seperti kecemasan, cemas terhadap dirinya dan cemasmemikirkan bayinya. Kecemasan tersebut yang dapat mempengaruhi kelancara pengeluaranASI pada ibu post partum. Tujuan untuk mengetahui hubungan antara kecemasan dengankelancaran pengeluaran air susu ibu pada ibu post partum selama dirawat di Rumah Sakit Ibudan Anak Kasih Ibu Manado. Metode menggunakan desain penelitian cross sectional.Sampel terdiri dari 68 responden dengan metode pengambilan sampelsecara non probabilitysampling dengan teknik purposive sampling. Hasil dengan menggunakan uji Chi – Squaretetapi tidak memenuhi syarat dan dilanjutkan dengan uji Fisher Exact pada tingkatkemaknaan 95%, didapatkan nilai ρ – Value 0,001 lebih kecil dari nilai signifikan 0,05.Kesimpulan ada hubungan antara kecemasan dengan kelancaran pengeluaran air susu ibupada ibu post partum selama dirawat di Rumah Sakit Ibu dan Anak Kasih Ibu Manado.Kata Kunci : Kecemasan, Kelancaran Pengeluaran ASI

scholarly journals Age as the Risk Factor that Affected the Increased Degree of Uterine Prolapse

2018 ◽  
Vol 1 (1) ◽  
pp. 20
Author(s):  
Shervil Kagayaita Sayko ◽  
Eighty Mardiyan Kurniawati ◽  
Pudji Lestari
Keyword(s):  
Elderly Women ◽  
Uterine Prolapse ◽  
Fisher Exact Test ◽  
Test Statistic ◽  
Cross Sectional ◽  
Significance Level ◽  
Exact Test ◽  
Significant Difference ◽  
The Relationship

Introduction: Uterine prolapse is a gynecological problem that women often experience with a prevalence of 50% and is predicted that the next 30 years will increase by 45% as life expectancy increases. Increased degrees of uterine prolapse have an impact on the deterioration of women's quality of life. The uterine prolapse is influenced by several mutually supportive factors. The purpose of this study was to analyze the relationship between these factors to the degree of uterine prolapse.Methods: This research is an observational analytic research with cross sectional approach. The number of samples were 65 patients with uterine prolapse at Policlinic Gynecology RSUD Dr. Soetomo Surabaya from 2015-2017. Sampling was done by consecutive sampling. To find out the significant level, the collected data will be tested with Fisher Exact Test statistic at significance level α = 0,05.Results: The result showed that there was significant difference between degree of uterine prolapse with age factor (p = 0,016) and obesity (p = 0,041). As for the parity factor (p = 0.508) there was no significant difference between the parity factor and the degree of uterine prolapse.Discussion: Age is a major factor affecting the degree of uterine prolapse, weakening of pelvic floor tissue and muscle in elderly women is the main cause. While on the obesity factor, there is no data to support that obesity is related to the degree of uterine prolapse because the trend indicates that the majority of patients are not obese. In contrast the parity factor, although according to the statistical test there is no difference to the degree of uterine prolapse, the trend shows that parity leads to increased incidence of uterine prolapse itself.Conclusion: Age is a factor that affects the degree of uterine prolapse.

scholarly journals Knowledge of pregnant women about anemia is related with adherence to iron tablets

2018 ◽  
Vol 26 (1) ◽  
pp. 26
Author(s):  
Baksono Winardi ◽  
Elga Caecaria Grahardika Andani
Keyword(s):  
Pregnant Women ◽  
Cross Sectional Study ◽  
P Value ◽  
Fisher Exact Test ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Exact Test ◽  
Study Population ◽  
Almost All

Objectives: to identify association between knowledge of pregnant women about anemia and the adherence to consume iron tablets in BPM Titik Suharti, Surabaya, IndonesiaMaterials and Methods: Observational analysis cross sectional study. Population consisted of 55 trimester pregnant women in BPM Titik Suharti, Surabaya, in March-April 2017. Samples were recruited using consecutive sampling. The number of sample was 35 respondents. Data were analyzed using chi-square test.Results: This research showed that all of the less knowledgeable women on anemia (100.00%) were non-adherent to consume iron tablets, almost all moderately knowledgeable women (92.9%) were adherent, and all of the fully knowledgeable women (100.00%) were adherent. Fisher exact test in significance level of 0.05 revealed p value equal to 0.0001, indicating association between knowledge about anemia and adherence to consume iron tablets at BPM Titik Suharti, Surabaya, Indonesia.Conclusion: There is an association between knowledge of pregnant women about anemia with adherence to iron tablets.

scholarly journals FAKTOR- FAKTOR YANG BERHUBUNGAN DENGAN PENURUNAN NAFSU MAKAN PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI TERAPI HEMODIALISIS (Studi Kasus di RSUD Prof. Dr. Margono Soekarjo)

2017 ◽  
Vol 1 (01) ◽  
pp. 23
Author(s):  
Umi Faza ◽  
Dyah Umiyarni Purnamasari ◽  
Saryono Yono
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Fisher Exact Test ◽  
Chi Square ◽  
Cross Sectional ◽  
Exact Test ◽  
Factors Associated ◽  
Consecutive Sampling ◽  
Chi Square Test ◽  
Cross Sectional Design

Abstract  The aim of this study was to determine factors associated with diminished appetite in CKD patients undergoing hemodialysis therapy. This study is an observational analytic research with cross sectional design. Population of this study was CKD outpatients undergoing hemodialysis therapy in July- August 2016 in Prof. Dr. Margono Soekarjo Hospitals. Amount of 58 subjects taken by consecutive sampling. Appetite, sex, age, length of hemodialysis, frequency of nausea/vomiting, and depression were measured using questionnaire. Subjects who diminished appetite were 58,6%. More than half subjects were male (56,9%). Amount of 84,5% subjects were adults (19-59 years), 63,8% undergoing hemodialysis >1year, 39,7% experienced nausea/ vomiting and 53,4% were depression. Based on Chi-Square Test/ Fisher Exact Test, diminished appetite significantly associated with length of hemodialysis (p=0,041), frequency of nausea/vomiting (p=0,014), and depression (p=0,002). Dominant factors affected diminished appetite were depression and length of hemodialysis. Diminished appetite in CKD patients undergoing hemodialysis therapy associated with length of hemodialysis, frequency of nausea/vomit, and depression. Keyword : appetite, chronic kidney disease, hemodialysi  Abstrak Penelitian ini bertujuan untuk mengetahui faktor- faktor yang berhubungan dengan penurunan nafsu makan pada pasien Gagal Ginjal Kronik (GGK) yang menjalani terapi hemodialisis. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Populasi dari penelitian ini adalah pasien GGK rawat jalan yang menjalani terapi hemodialisis pada bulan Juli- Agustus 2016 di RSUD Prof. Dr. Margono Soekarjo Purwokerto. Sebanyak 58 subjek diambil dengan cara consecutive sampling. Nafsu makan, jenis kelamin, usia, lama hemodialisis, frekuensi mual/muntah, dan depresi diukur menggunakan kuesioner. Responden yang mengalami penurunan nafsu makan sebanyak 58,6%. Lebih dari separuh responden (56,9%) berjenis kelamin laki- laki dan 84,5% responden berusia dewasa (19-59 tahun). Sebanyak 63,8% responden menjalani hemodialisis >1tahun. Responden yang mengalami mual/muntah berat sebanyak 39,7% dan 53,4% mengalami depresi. Berdasarkan analisis bivariat menggunakan Uji Chi- Square/ Fisher Exact diperoleh hasil bahwa nafsu makan berhubungan secara signifikan dengan lama hemodialisis (p=0,041), frekuensi mual/ muntah (p=0,014), dan depresi (p=0,002). Faktor dominan yang mempengaruhi penurunan nafsu makan adalah depresi dan lama hemodialisis. Penurunan nafsu makan pada pasien GGK yang menjalani terapi hemodialisis berhubungan dengan lama hemodialisis, frekuensi mual/muntah, dan depresi. Kata kunci : gagal ginjal, hemodialisa, nafsu makan  

Abstract 537: Higher Prevalence of Risk Alleles for Hyperuricemia Parallels Elevated Incidence of Gout and Growing Risk for Cardiovascular Diseases in a Hmong Population

2014 ◽  
Vol 34 (suppl_1) ◽  
Author(s):  
Youssef M Roman ◽  
Jenny D Xiong ◽  
Jeremiah S Menk ◽  
Kathleen Culhane-Pera ◽  
Robert J Straka
Keyword(s):  
Elevated Serum ◽  
Asian Population ◽  
Allele Frequencies ◽  
Fisher Exact Test ◽  
Snp Analysis ◽  
Cvd Risk ◽  
Significance Level ◽  
Exact Test ◽  
Risk Alleles ◽  
Increased Risk

Introduction: Hyperuricemia (HU) is the strongest predictor of gout and highly associated with major CVD including hypertension, HF, and CKD. The Hmong, a unique Asian population numbering > 60,000 in Minnesota, have a two-fold increased risk of gout compared to non-Hmong, rising prevalence of CVD, and may differ from other Asian populations in these regards. A genetic predisposition to elevated Serum Uric Acid (SUA) may help identify individuals at risk for gout and CVD. We quantified the Minor Allele Frequencies (MAFs) of known genetic variants (SNPs) associated with HU and compared the MAFs between our Hmong sample and both a reference (HapMap) population of Caucasian (CEU) as well as Han-Chinese (CHB). Methods: Salivary DNA from 235 self-identified Hmong was genotyped using either a Sequenom (iPLEX Gold) or TaqMan approach. MAFs for seven SNPs within candidate genes ( SLC2A9, SLC22A12, PDZK1, and ABCG2 ) identified by GWAS, were determined in our Hmong sample. Associations between HU and genotype were examined for 57/235 Hmong with known SUA levels. A Chi-Square or Fisher exact test with a Bonferroni corrected significance level (<0.007) was used to evaluate MAF differences. Mean SUA concentrations were compared by genotype using one-way ANOVA. Results: Our Hmong participant's age [mean (±SD)] was 30.2 (15.4) years, with >61% overweight or obese and a mean (±SD) SUA of 6.3 (1.7) mg/dL. Although the frequency of risk alleles in the Hmong were significantly higher compared to CEU (6/7) and CHB (3/7) populations, independent SNP by SNP analysis did not show a clear association with SUA. Risk allele frequencies were always more frequent in the Hmong versus comparator groups. Conclusion: MAFs of selected SNPs for HU are not independent of race. The higher prevalence of risk alleles for HU in the Hmong versus CEU and CHB populations may partly explain the clinically observed higher prevalence of gout and CVD risk in the Hmong. Although sample size precludes a robust assessment of an association between genotype and SUA, to our knowledge this is the first study to examine the genetic basis of HU in the Hmong.

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