scholarly journals Metabolic syndrome in the 1982 Pelotas cohort: effect of contemporary lifestyle and socioeconomic status

2010 ◽  
Vol 54 (4) ◽  
pp. 390-397 ◽  
Author(s):  
Vera Maria Freitas da Silveira ◽  
Bernardo L. Horta ◽  
Denise P. Gigante ◽  
Mario Renato Azevedo Junior

OBJECTIVES: Describe the prevalence of metabolic syndrome, and its association with contemporary lifestyle factors. SUBJECTS AND METHODS: In 2004-2005, 4,296 subjects of the 1982 Pelotas Birth Cohort were evaluated, and metabolic syndrome (MetS) was assessed in 3,599 according to the NCEP-ATP III and IDF criteria. RESULTS: Prevalence of MetS was 5.9% and 6.7% for NCEP-ATPIII and IDF, respectively. Smoking, alcohol intake, and physical activity were not associated with MetS. Among men, the body mass index (BMI) was associated with MetS - overweight [RR: 3.14 (95% CI, 1.97-5.00)] and obese subjects [RR: 17.41 (95% CI, 11.85-25.60)]. In women, family income and schooling were inversely associated with MetS, overweight increased the risk of MetS 7.73 (95% CI, 3.65-16.38) times and obesity 40.67 (95% CI, 20.85-79.33) times. CONCLUSIONS: MetS was more prevalent among men according to NCEP-ATP III criteria, and obesity was the main risk factor.

1994 ◽  
Vol 72 (01) ◽  
pp. 058-064 ◽  
Author(s):  
Goya Wannamethee ◽  
A Gerald Shaper

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.


Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1952
Author(s):  
Anna Johansson ◽  
Isabel Drake ◽  
Gunnar Engström ◽  
Stefan Acosta

Risk factors for ischemic stroke is suggested to differ by etiologic subtypes. The purpose of this study was to examine the associations between modifiable and non-modifiable risk factors and atherothrombotic stroke (i.e., excluding cardioembolic stroke), and to examine if the potential benefit of modifiable lifestyle factors differs among subjects with and without predisposing comorbidities. After a median follow-up of 21.2 years, 2339 individuals were diagnosed with atherothrombotic stroke out of 26,547 study participants from the Malmö Diet and Cancer study. Using multivariable Cox regression, we examined non-modifiable (demographics and family history of stroke), semi-modifiable comorbidities (hypertension, dyslipidemia, diabetes mellitus and atherosclerotic disease), and modifiable (smoking, body mass index, diet quality, physical activity, and alcohol intake) risk factors in relation to atherothrombotic stroke. Higher age, male gender, family history of stroke, and low educational level increased the risk of atherothrombotic stroke as did predisposing comorbidities. Non-smoking (hazard ratio (HR) = 0.62, 95% confidence interval (CI) 0.56–0.68), high diet quality (HR = 0.83, 95% CI 0.72–0.97) and high leisure-time physical activity (HR = 0.89, 95% CI 0.80–0.98) decreased the risk of atherothrombotic ischemic stroke independent of established risk factors, with non-significant associations with body mass index and alcohol intake. The effect of the lifestyle factors was independent of predisposing comorbidities at baseline. The adverse effects of several cardiovascular risk factors were confirmed in this study of atherothrombotic stroke. Smoking cessation, improving diet quality and increasing physical activity level is likely to lower risk of atherothrombotic stroke in the general population as well as in patient groups at high risk.


2021 ◽  
pp. 1-10
Author(s):  
Marina Rodríguez Cintas ◽  
Sara Márquez ◽  
Javier González Gallego

BACKGROUND: Sedentarism is an important modifiable risk factor in the struggle against cancer. In the last decades, the relationship between physical activity and different types of cancer has been investigated in depth. OBJECTIVE: To provide an overview of the literature on the effectiveness of physical activity in reducing the risk to develop bladder cancer and improving health-related quality of life in patients. METHODS: A systematic review was conducted through a search of the Embase, Cochrane, PubMed, Scopus, and Web of Science (WOS) databases to seek information and PRISMA system to delimitate the research. Outcomes included in searches were physical activity, tobacco consumption, obesity, body mass index, and metabolic syndrome, associated with bladder cancer and quality of life. RESULTS: Database searches identified 394 records, of which 75 were duplicated. A total of 280 articles were excluded based on abstract screening. An additional 16 full-text articles were excluded because they did not meet the eligibility criteria. Overall, 21 of the 23 studies included in the review reported beneficial effects of physical activity in bladder cancer. The majority of papers found that physical activity is a significant factor in reducing the risk of bladder cancer. Moreover, physical activity improves health-related quality of life in bladder cancer survivors, and diminishes both recurrence and mortality in those who engage in regular activity. Lastly, physical inactivity is associated with increased body mass index, obesity, metabolic syndrome, type 2 diabetes and unfavourable energy balance, which led to a greater probability of suffering from bladder cancer. CONCLUSIONS: These data reinforce the importance of promoting a healthy lifestyle to reduce the risk of bladder cancer and to improve survivorship and health-related quality of life of patients.


Retos ◽  
2016 ◽  
pp. 271-274
Author(s):  
Manuela Costa ◽  
Tânia Oliveira ◽  
Jorge Mota ◽  
Maria Paula Santos ◽  
José Carlos Ribeiro

Objective: The objective of this study was twofold. First, analyze physical activity (PA) levels during physical education (PE) with different durations (45 and 90 minutes) according to student’s obesity status. Secondly, we examine the relative contribution of 45 and 90 minutes PE (45PE and 90PE) for the compliance of the daily PA recommendations according to the body mass index (BMI). Methods: Four public schools were analyzed. The sample comprised 472 youngsters (266 girls) aged between 10 and 18 years old. PA was assessed using an Actigraph accelerometer. The participants were categorized as non-overweight (NOW) and overweight/obese (OW) according to the sex-adjusted BMI. Results: The proportion of Moderate and Vigorous Physical Activity (MVPA) was lower than the 50% recommended by guidelines regardless the PE duration. Our data showed that only 26% of NOW and 13% of OW in the 45PE achieved the recommended levels while 17% of NOW and 11% of OW achieved the recommendation in 90PE. Overall, the 90PE had a higher absolute contribution for daily MVPA recommendations compliance than 45PE. Conclusion: During PE classes youngsters spent a reduced amount of time in MVPA, independently of their weight status.Resumen. Objetivo: Este estudio tiene un doble objetivo. En primero lugar, analizar los niveles de la actividad física durante la educación física con diferentes duraciones (45 y 90 minutos) de acuerdo con el estado de la obesidad de los alumnos. En segundo lugar, se analiza la contribución relativa de 45 y 90 minutos de la educación física para el cumplimiento de las recomendaciones diarias de actividad física según el índice de masa grasa. Métodos: cuatro escuelas públicas fueran analizadas. La muestra fue de 472 jóvenes (266 chicas) con edades entre los 10 y 18 años. La actividad física fue medida utilizando un acelerómetro Actigraph. Los participantes fueran clasificados como sin sobrepeso y con sobrepeso/obesidad de acuerdo con el índice de masa grasa ajustado al género. Resultados: La proporción de la actividad física moderada y vigorosa fue inferior al 50% recomendado por las recomendaciones independiente de la duración de la clase de educación física. Nuestros datos muestran que solo unos 26% de los niños sin sobrepeso y unos 13% de niñoss con sobrepeso/obesidad llegaron al los niveles recomendados en las clases de 45 min, mientras el 17% de los jóvenes sin sobrepeso y el 11% con sobrepeso/obesidad han logrado las recomendaciones en las clases de 90 min. En general, las clases de 90 min tienen una mayor contribución para cumplimiento de las recomendaciones diarias de actividad física moderada a vigorosa do que las clases de 45 min. Conclusión: Durante las clases de educación física los jóvenes tuvieran una cantidad reducida de tiempo en actividad física moderada a vigorosa, independiente de su estado de peso.


2017 ◽  
Vol 3 (2) ◽  
Author(s):  
Wiwik Agustina ◽  
Ekawarsih Lampah

Abstract : Central obesity is a public health problem that can occur in the world. Central obesity is one of the causes of degenerative diseases such as type 2 diabetes mellitus, dyslipidemia, cardiovascular disease, hypertension, cancer, sleep apnea, and metabolic syndrome. Metabolic syndrome is a condition in which a person develops hypertension, central obesity, dyslipidemia, and insulin resistance at the same time. Degenerative diseases are influenced by many factors: age, physical activity, emotional mental state, nutrition and hormonal contraceptive use. This study aims to determine the determinant factors of central obesity. The study design used was descriptive explorative. The sample of research is 40 respondents. The selected sample corresponds to the inclusion criteria.Prevalence of central obesity in Sukun Kota Malang counted 40 respondents, with result almost all respondents 90% have age which is at risk of central obesity, physical activity almost half of respondents 53% have aktvitas physical and 47% have activity light, emotional mental condition most of respondent 65% have normal emotional mental condition, nutrition most respondents 63% have normal nutrition, and hormonal contraceptive use most of respondents 67% of hormonal contraceptive users. It was concluded that the most common risk factor in obese people in Puskesmas  Ciptomulyo  Kecamatan  Sukun  Kota  Malang, was the age factor, so it can be suggested to the public to further increase physical activity, and switch to using non-hormonal contraception.Key Word : central obesity, risk factor Abstrak : Obesitas  sentral  merupakan  masalah  kesehatan  masyarakat  yang  dapat   terjadi  di  dunia.  Obesitas  sentral  merupakan  salah  satu  penyebab  terjadinya  penyakit – penyakit  degeneratif seperti  diabetes  mellitus  tipe  2,  dyslipidemia,  penyakit  kardiovaskular,  hipertensi,  kanker,  sleep  apnea,  dan  sindrom  metabolic. Sindrom  metabolik  adalah  kondisi  dimana  seseorang  mengalami hipertensi,  obesitas  sentral,  dyslipidemia,  dan  resistensi  insulin  pada  waktu  yang  bersamaan. Penyakit degenerative dipengaruhi oleh banyak faktor yaitu usia, aktivitas  fisik, kondisi  mental  emosional, nutrisi dan  penggunaan  kontrasepsi  hormonal. Penelitian ini bertujuan untuk mengetahui  faktor determinan terjadinya obesitas sentral. Desain  studi   yang  digunakan  adalah deskriptif eksploratif. Sampel  penelitian  sebanyak 40  responden. Sampel yang dipilih sesuai dengan kriteria inklusi. Prevalensi obesitas  sentral  di Sukun Kota Malang sebanyak 40 responden, dengan hasil hampir seluruh responden  90% memiliki  usia  yang  berisiko mengalami obesitas sentral, aktivitas  fisik    hampir setengah responden  53%  memiliki aktvitas fisik sedang  dan 47%  memiliki  aktivitas  ringan, kondisi  mental  emosional  sebagian  besar responden 65%  memiliki  kondisi  mental  emosional  normal, nutrisi  sebagian  besar responden  63%  memiliki nutrisi normal, dan penggunaan  kontrasepsi  hormonal  sebagian besar responden  67%  pengguna  kontrasepsi  hormonal meningkat. Disimpulkan  bahwa faktor risiko yang paling banyak ditemukan pada orang yang mengalami obesitas di  Puskesmas  Ciptomulyo  Kecamatan  Sukun  Kota  Malang adalah faktor usia dengan demikian dapat disarankan kepada masyarakat agar lebih aktivitas fisik, dan beralih menggunakan kontrasepsi yang tidak mengandung hormon.Kata Kunci : obesitas sentral, faktor risiko


2018 ◽  
Vol 7 (1) ◽  
pp. 43-48
Author(s):  
Deny Yudi Fitranti ◽  
Fillah Fithra Dieny ◽  
Binar Panunggal ◽  
Vintantiana Sukmasari ◽  
Gardinia Nugrahani

Background : The content of water in fat cells in obese people is lower than muscle cells so that obese people are more easily dehydrated.Objective : The purpose of this study is to determine the risk factors of dehydration in adolescents.Methods : This study was a cross sectional study which began with screening of 168 students at SMA N 1 and 2 Semarang and found 63 students fulfilled the inclusion criteria. Subjects were selected by consecutive sampling. The dependent variable of this study is hydration status measured by the urine spesific gravity method. The independent variables consisted of obesity status that determined by the BMI/Age Z-score value, fluid intake was assessed using Semi Quantitative Food Frequency Questionnaire (SQ-FFQ), physical activity was assessed using physical activity questionnaire, whereas knowledge regarding fluid was assessed by questionnaire. Data were analyzed using Chi Square test.Results ; There were 52,4% (n=33) subjects who were obese and only 9,5% (n=6) subjects were well-hydrated. The incidence of dehydration in obese adolescents (63,6%) was higher than non obese adolescents (36,7%). Obese subjects was 1.73 times more dehydrated than non obese subjects. Subject with deficiency of fluid intake was 1,85 times more dehydrated than subject with adequate fluid intake. Knowledge regarding fluid and physical activity was not a risk factor for dehydration in adolescents.Conclusion :Obesity and inadequate fluid intake ia risk factor for dehydration in adolescents


Author(s):  
Alba Marcos-Delgado ◽  
Tania Fernández-Villa ◽  
Miguel Ángel Martínez-González ◽  
Jordi Salas-Salvadó ◽  
Dolores Corella ◽  
...  

The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the Predimed-Plus study. A total of 6875 subjects between 55 and 75 years of age with MetS were selected and randomized in 23 Spanish centers. Subjects were classified according to categories of body mass index (BMI). PA was measured with the validated Registre Gironí del Cor (REGICOR) questionnaire and subjects were classified according to their PA level (light, moderate, vigorous) and the HRQoL was measured with the validated short-form 36 (SF-36) questionnaire. By using the ANOVA model, we found a positive and statistically significant association between the level of PA and the HRQoL (aggregated physical and mental dimensions p < 0.001), but a negative association with higher BMI in aggregated physical dimensions p < 0.001. Furthermore, women obtained lower scores compared with men, more five points in all fields of SF-36. Therefore, it is essential to promote PA and body weight control from primary care consultations to improve HRQoL, paying special attention to the differences that sex incurs.


1998 ◽  
Vol 12 (4) ◽  
pp. 227-233 ◽  
Author(s):  
Abdulwahab Naser Al-Isa

A random sample of 585 Kuwaiti college women was studied in 1997 for factors associated with overweight and obesity. Weight and height were measured. The index of adiposity used was the body mass index (BMI), which is the weight in kilograms divided by the height squared (W/H2). The women were classified as overweight or obese (BMI > 25 or > 30 Kg/m2). The associated factors obtained through questionnaires included age, marital status, area of residence, number of siblings, (brothers, sisters, total), suffering from a chronic disease, obesity among parents, parents' education and occupation, number of major meals eaten, eating between meals, family income, number of servants, number of people living at home, exercising, last dental and physical checkup, dieting, year of study, highest desired degree, countries prefer visiting, and socioeconomic status (SES). The results of the study revealed that 27.2 and 7.2% of the students were overweight (BMI > 25 Kg/m2) and obese (BMI > 30 Kg/m2), respectively. Factors that were found to be significantly associated with overweight and obesity among the women included number of brothers, having a chronic disease, obesity among parents, dieting and countries prefer visiting. Logistic regression analysis of significant associated factors revealed that the same factors contributed to the development of overweight and obesity except number of brothers and having a chronic disease.


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