scholarly journals Prevalence of cholelithiasis in patients with chagasic megaesophagus

2011 ◽  
Vol 44 (3) ◽  
pp. 324-326 ◽  
Author(s):  
Eduardo Crema ◽  
Ellen Caroline Rosa Resende Silva ◽  
Priscila Melo Franciscon ◽  
Virmondes Rodrigues Júnior ◽  
Aiodair Martins Júnior ◽  
...  
Keyword(s):  
General Population ◽  
Chagas Disease ◽  
Biliary Tract ◽  
Surgical Procedure ◽  
Clinical Findings ◽  
Parasympathetic Nerve ◽  
Subtotal Esophagectomy ◽  
Significant Difference ◽  
The Mean ◽  
Chagasic Megaesophagus

INTRODUCTION: The prevalence of cholelithiasis in the general population ranges from 9 to 18%. This prevalence is known to be higher in the presence of parasympathetic nerve damage of the biliary tract either due to surgery (vagotomy) or neuronal destruction (Chagas disease). The objective of this study was to evaluate the association of cholelithiasis and chagasic or idiopathic megaesophagus. METHODS: The ultrasound scans of 152 patients with megaesophagus submitted to cardiomyotomy and subtotal esophagectomy surgery were evaluated. The presence of cholelithiasis was compared between chagasic and idiopathic esophagopathy and ultrasound and clinical findings were correlated with age, sex and race. RESULTS: A total of 152 cases of megaesophagus, including 137 with chagasic megaesophagus and 15 with idiopathic megaesophagus, were analyzed. The mean age was 56.7 years (45-67) in the 137 patients with chagasic megaesophagus and 35.6 years (27-44) in the 15 cases of idiopathic megaesophagus, with a significant difference between the two groups (p < 0.0001). The group with chagasic megaesophagus consisted of 59 (43%) women and 78 (56.9%) men, while the group with idiopathic megaesophagus consisted of 8 (53.3%) women and 7 (46.6%) men, showing no significant difference between the groups. Of the 137 patients with confirmed chagasic megaesophagus, 39 (28.4%) presented cholelithiasis versus one case (6.6%) in the 15 patients with idiopathic megaesophagus. CONCLUSIONS: The prevalence of cholelithiasis is high in patients with chagasic megaesophagus and preoperative ultrasound should be performed routinely in these patients in order to treat both conditions during the same surgical procedure.

Surgical Treatment of Spinal Extradural Arachnoid Cysts in the Thoracolumbar Spine

Neurosurgery ◽  
2012 ◽  
Vol 71 (2) ◽  
pp. 278-284 ◽  
Author(s):  
Haruki Funao ◽  
Masaya Nakamura ◽  
Naobumi Hosogane ◽  
Kota Watanabe ◽  
Takashi Tsuji ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Surgical Procedure ◽  
Thoracolumbar Spine ◽  
Neurological Recovery ◽  
Dural Defect ◽  
Total Resection ◽  
Duration Of Symptoms ◽  
Significant Difference ◽  
The Mean ◽  
Poor Outcomes

Abstract BACKGROUND: Because an idiopathic spinal extradural arachnoid cyst (SEAC) is rare, its optimal surgical treatment remains controversial. OBJECTIVE: To evaluate the results of surgical treatments for SEACs and to clarify features of the disease associated with poor outcomes. METHODS: Twelve patients with SEACs who underwent surgery at our hospital between 1988 and 2008 were examined retrospectively. The mean follow-up period was 4.7 years. Total resection of the cyst was performed in 7 patients and closure of the dural defect without cyst resection in 5 patients. Surgical outcomes were evaluated with regard to the duration of symptoms, the size of the cyst, and the surgical procedure used. RESULTS: Neurological recovery was observed in all patients, and there was no recurrence. Poor outcomes were observed in patients with a long duration of symptoms (&gt;1 year, P &lt; .01) and large cyst size (&gt;5 vertebrae, P &lt; .05). The surgical procedure had no significant association with the postoperative neurological recovery. However, there was a significant difference in the degree of the mean postoperative kyphotic angle between the patients treated by total resection of the cyst (9.7 degrees) and those treated by closure of the dural defect without cyst resection through selective laminectomy (2.2 degrees) (P &lt; .01). CONCLUSION: There was no significant difference in postoperative neurological recovery between the 2 surgical procedures. However, closure of the dural defect without cyst resection was less invasive, preventing postoperative kyphotic deformity of the thoracolumbar spine.

scholarly journals 1180 2D and 3D assessment of the left ventricle volume and ejection fraction in a general population

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
F Ericsson ◽  
B Tayal ◽  
K Hay Kragholm ◽  
T Zaremba ◽  
N Holmark Andersen ◽  
...  
Keyword(s):  
General Population ◽  
Left Ventricle ◽  
Ejection Fraction ◽  
Large Population ◽  
Systolic Volume ◽  
End Diastolic Volume ◽  
Significant Difference ◽  
End Systolic Volume ◽  
The Mean ◽  
2D And 3D

Abstract Introduction In standard practice, LV volumes and EF are estimated by 2D technique. 3D echocardiographic assessment seems more reliable; however, this method has not yet been validated in the general population. Purpose To validate 3D echocardiography in a large population sample and investigate differences between 2D and 3D LVEF and volumes Methods In The Copenhagen City Heart Study, 4466 echocardiograms were available for analysis. The echocardiograms were obtained during four consecutive heartbeats in both 2D and 3D with GE Vivid E9. Offline analysis was performed on EchoPac v. 201. LVEF was calculated by the modified Simpsons Biplane Auto EF for 2D and by the 4LVQ method for 3D. Results The study included 2090 echocardiograms. The mean 2D LVEF was 57.3 ± 6.1% (IQR 54 - 61%) and 51.7 ± 7.9% (IQR 47 - 57%) by 3D. The mean end-diastolic volume (EDV) and end-systolic volume (ESV) by 2D and 3D techniques were: EDV 2D 106.1 ± 29.6 ml vs EDV 3D 128.2 ± 32.3 ml , ESV 2D 45.7 ± 15.6 ml vs. ESV 3D 45.7 ± 20.7 , p &lt; 0.05 among all variables. The average difference of means between 2D and 3D LVEF was 5.6 ± 11.2%, -22.1 ± 56.8 ml for EDV, and -16.9 ± 32.9 ml for ESV. The correlation coefficient for LVEF was 0.42, EDV 0.76 and for ESV 0.70. Conclusion In our study, we found a significant difference in both LVEF and ventricular volumes when comparing 2D echocardiograms with 3D. 3DE had, in general, lower LVEF, higher EDV and ESV compared to 2D. Table 1: Summary of results Table 1 - Summary of results n = 2090 Variable Min Max Mean IQR (25-75) p-value LVEF, 2D (%) 18 76 57.3 ± 6.1 54-61 &lt; 0.05 LVEF, 3d (%) 13 77 51.7 ± 7.9 47-57 &lt; 0.05 EDV, 2D (ml) 13 275 106.1 ± 29.6 85-123.8 &lt; 0.05 EDV, 3D (ml) 50 270 128.2 ± 32.3 106-148 &lt; 0.05 ESV, 2D (ml) 15 150 45.7 ± 15.6 35-54 &lt; 0.05 ESV, 3D (ml) 13 185 45.7 ± 20.7 48-74 &lt; 0.05 LVEF: left ventricle ejection fraction, EDV: end-diastolic volume, ESV: end systolic volume, IQR: Inter-quartile range Abstract 1180 Figure 1: Correlation and BA-plot

Clinical Significance of Cryofibrinogenemia: Possible Pathophysiological Link with Raynaud’s Phenomenon

2011 ◽  
Vol 39 (1) ◽  
pp. 119-124 ◽  
Author(s):  
MUHAMMAD S. SOYFOO ◽  
AHMED GOUBELLA ◽  
ELIE COGAN ◽  
JEAN-CLAUDE WAUTRECHT ◽  
ANNICK OCMANT ◽  
...  
Keyword(s):  
Raynaud’S Phenomenon ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Raynaud's Phenomenon ◽  
Clinical Findings ◽  
University Hospital ◽  
Significant Difference ◽  
Primary Raynaud’S Phenomenon ◽  
The Mean ◽  
Mean Concentration

Objective.To describe the clinical findings and prevalence of patients with cryofibrinogenemia (CF) and to determine whether CF is associated with primary Raynaud’s phenomenon.Methods.Between June 2006 and December 2009, 227 patients were tested for CF in a single university hospital. Forty-five patients with primary Raynaud’s phenomenon were tested for CF.Results.A total of 117 patients with CF without cryoglobulinemia were included. The main clinical manifestations included skin manifestations (50%) and arthralgia (35%). There were 67 patients with primary CF and 50 patients with secondary CF. There was no significant difference in the mean concentration of the cryoprecipitate in primary CF as compared to the secondary form (172 ± 18.6 vs 192 ± 20.9 mg/dl, respectively; p = 0.41). Highest concentrations of cryoprecipitate were observed in those containing fibrinogen only as compared to cryoprecipitates containing fibrinogen and fibronectin (301 ± 43.5 vs 125 ± 10.6 mg/dl; p < 0.001). Patients having skin necrosis (n = 3) had significantly higher values of cryofibrinogen compared to those without necrosis (638 ± 105 vs 160 ± 10.2 mg/dl; p = 0.0046). Among the 45 patients with primary Raynaud’s phenomenon, 36 had associated CF. There was no significant difference in the mean concentration of the cryoprecipitate in these patients compared to those with primary CF.Conclusion.There seems to be a significant correlation between cryofibrinogen concentration and the severity of the clinical signs, particularly when cryoprecipitate is composed of fibrinogen alone. CF might have a possible pathophysiological role in primary Raynaud’s phenomenon.

Posterior-Lateral Foraminotomy as an Exclusive Operative Technique for Cervical Radiculopathy: A Review of 846 Consecutively Operated Cases

Neurosurgery ◽  
1983 ◽  
Vol 13 (5) ◽  
pp. 504-512 ◽  
Author(s):  
Charles M. Henderson ◽  
Robert G. Hennessy ◽  
Henry M. Shuey ◽  
E. Grant Shackelford
Keyword(s):  
Lumbar Disc ◽  
Operative Procedure ◽  
Venous Pressure ◽  
Air Embolism ◽  
Cervical Radiculopathy ◽  
Clinical Findings ◽  
Motor Deficit ◽  
Arm Pain ◽  
Significant Difference ◽  
The Mean

Abstract Between 1963 and 1980, one or more posterior-lateral foraminotomies were performed for simple cervical radiculopathy as the sole operative procedure for 736 patients. One hundred three patients (14%) required a second posterior procedure, but only 24 (3%) cases represented true recurrent radiculopathy. There were 13 minor complications (1.5%) and no deaths or detectable incidence of air embolism. All operations were done with the patient in the sitting position. Central venous pressure monitoring was used only infrequently. There was a 96% incidence of relief of significant arm pain and/or paresthesia and a 98% incidence of resolution of preoperatively present motor deficit. Eight hundred twenty-eight procedures (98%) were preceded by Pantopaque cervical myelography. There was a 71.5% incidence of correlation between preoperative clinical findings (both sensory and motor) and operative findings. In 13% of the cases, two spaces were thought by the operating surgeon to be equally involved by the spondylotic process. Most (91.5%) of the patients describe themselves as either “good or excellent” postoperatively. There was no significant difference postoperatively regarding results or recurrence between patients with suspected soft or hard disc protrusions and those with strictly spondylotic radiculopathy. Nor was there any statistical difference in results among the three patient population groups (“private” vs. compensation vs. liability). The mean length of time to return to work or other “normal” activities was 9.4 weeks. The mean length of follow-up time was 146 weeks (2.8 years). There was an associated incidence of significant lumbar disc and/or foraminal disease requiring operation of 33.4%.

scholarly journals Transcaruncular Medial Wall Orbital Decompression: An Effective Approach for Patients with Unilateral Graves Ophthalmopathy

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Robert H. Hill ◽  
Craig N. Czyz ◽  
Thomas A. Bersani
Keyword(s):  
Thyroid Dysfunction ◽  
Clinical Findings ◽  
Mean Difference ◽  
Medial Wall ◽  
Orbital Decompression ◽  
Postoperative Results ◽  
Graves Ophthalmopathy ◽  
Significant Difference ◽  
Graves Orbitopathy ◽  
The Mean

Purpose. To evaluate the reduction in proptosis, incidence of postoperative diplopia, and postoperative globe symmetry after transcaruncular medial wall decompression in patients with unilateral Graves ophthalmopathy.Methods. Retrospective review of 16 consecutive patients who underwent unilateral transcaruncular medial wall orbital decompression from 1995 to 2007. The diagnosis of Graves ophthalmopathy was based on history and clinical findings including proptosis, lagophthalmos, lid retraction, motility restriction, and systemic thyroid dysfunction.Results. The mean reduction in proptosis was 2.3 mm. The mean difference in exophthalmometry preoperatively between the two eyes in each patient was 3.1 mm whereas postoperatively the mean difference was 1.1 mm (P=0.0002). Eleven of 16 patients (69%) had 1 mm or less of asymmetry postoperatively. There was no statistically significant difference in the incidence of diplopia pre- and postoperatively (P=1.0).Conclusions. Medial wall orbital decompression is a safe and practical surgical approach for patients with unilateral Graves orbitopathy. The procedure carries a low risk of morbidity and yields anatomic retrusion of the globe that is comparable to other more invasive methods and may yield more symmetric postoperative results.

scholarly journals Assessment of the relationship between serum uric acid levels and liver enzymes activity in Bangladeshi adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Noyan Hossain Molla ◽  
Rahanuma Raihanu Kathak ◽  
Abu Hasan Sumon ◽  
Zitu Barman ◽  
Ananya Dutta Mou ◽  
...  
Keyword(s):  
Uric Acid ◽  
General Population ◽  
Serum Uric Acid ◽  
Liver Enzymes ◽  
Multinomial Logistic Regression ◽  
Adult Population ◽  
Enzymes Activity ◽  
Significant Difference ◽  
The Mean ◽  
The Relationship

AbstractSerum uric acid (SUA) level has been suggested to be associated with cardiovascular disease, diabetes and metabolic syndrome. However, little is known about the relationship between SUA and liver enzymes activity in the general population. The present study aimed to assess the relationship between SUA and serum liver enzymes in an adult population in Bangladesh. In this cross-sectional study, a total of 410 blood samples were collected from apparently healthy adults aged > 18 years. SUA, liver enzymes, lipid profile and other biochemical markers were measured in the collected samples by using standard methods. Multinomial logistic regression model was used to assess the relationship between SUA and elevated levels of liver enzymes among the participants. Overall, the prevalence of hyperuricemia was 30.1% with 32.2% in male and 18.6% in female participants. About 33% of the participants had at least one or more elevated levels of liver enzymes. The mean level of SUA was significantly higher in males (389.3 ± 96.9 µmol/L) than in the female (290.4 ± 89.8 µmol/L) subjects (p < 0.001). There was a significant difference in the mean levels of serum ALT and GGT between the male (34.5 ± 16.0 U/L and 26.7 ± 19.5 U/L, respectively) and female (25.0 ± 13.0 U/L and 19.5 ± 13.2 U/L, respectively) participants (p < 0.001 and p < 0.01, respectively). An increasing trend was observed in the mean levels of serum ALT and GGT across the SUA quartile groups (p < 0.001 and p < 0.01, respectively). SUA showed a positive and significant correlation with serum ALT (p < 0.001) and GGT (p < 0.01). In further statistical analysis after adjustment for potential confounders, SUA showed an independent and significant association with serum ALT and GGT in all regression models. In conclusion, SUA was strongly associated with serum levels of ALT and GGT after adjustment for potential confounders. More prospective studies are needed to clarify the complex relationship between SUA and liver enzymes in the general population.

Early Effect of Exogenous Na Hyaluronate on Mucociliary Clearance

2005 ◽  
Vol 19 (3) ◽  
pp. 244-247 ◽  
Author(s):  
Altan Yildirim ◽  
Bulent Turgut ◽  
Ali Ihsan Bebek ◽  
Cesur Gumus ◽  
Sinan Kocaturk ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Surgical Procedure ◽  
Mucociliary Clearance ◽  
Physiological Solution ◽  
Control Group ◽  
Scintigraphic Imaging ◽  
Early Effect ◽  
Significant Difference ◽  
The Mean ◽  
Maxillary Sinuses

Background An animal study is performed to determine the early effect of 1% Na hyaluronate on mucociliary clearance function. Methods One percent of Na hyaluronate was introduced into the maxillary sinuses of rabbits by anterior antrostomy. A physiological solution of 1% NaCl was introduced into the maxillary sinuses of a control group to equalize the influence of Na for both groups. The treatment material was sprayed with an atomizer for coating the maxillary sinus lining. Technetium-99m diethylenetriamine pentaacetate dynamic scintigraphic imaging was performed to evaluate mucociliary clearance function on all rabbits 72 hours after the surgical procedure. Results Although the mean rate of mucociliary clearance of the Na hyaluronate group was slightly worse than the control group; there was no statistically significant difference between them. Conclusion There is no early effect of exogenous 1% Na hyaluronate on mucociliary clearance function.

scholarly journals Serum Leptin Concentrations in Turkish Parkinson’s Disease Population

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Betul Ozdilek ◽  
Gulay Kenangil
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Body Composition ◽  
Rating Scale ◽  
Clinical Findings ◽  
Clinical Prognosis ◽  
Significant Difference ◽  
Yahr Scale ◽  
The Mean ◽  
And Gender

Objectives. To investigate leptin levels and their relationship to body composition and demographic and clinical characteristics of Turkish patients with Parkinson’s disease (PD).Patients and Methods. Forty eligible PD patients and 25 healthy controls were included in the study. Body composition measurements (height, weight, waist circumference (WC), and body mass index (BMI)) of the whole sample and clinical findings of PD patients were evaluated in the on-state. A single 5 mL fasting blood sample was obtained from each participant in the morning. Severity of PD was evaluated using the Hoehn and Yahr scale and the Unified Parkinson’s Disease Rating Scale.Results. The mean age of the patients and controls was60.8±9.4and61.8±5.8years, while the mean BMI was30.17±5.10and28.03±3.23and the mean leptin levels were6.8±6.9and3.9±3.8 ng/mL, respectively. Only age and gender were correlated with leptin levels. There was a significant difference (P<0.001) in leptin levels between male (3.6±3.1 ng/mL) and female (14.3±7.7 ng/mL) PD patients. Among the male PD patients, older age and higher BMI and WC values were associated with higher mean leptin levels. There was not any significant relationship between leptin levels and clinical findings in PD patients.Conclusion. These results may suggest that leptin levels have no determinative role in the follow-up of PD patients with regard to the severity and clinical prognosis of PD.

scholarly journals Prevalência de alteração do frênulo de língua em cantores com disfonias comportamentais / Prevalence of language frenulum alteration in singers with behavioral dysphonies

2021 ◽  
Vol 66 (1u) ◽  
pp. 1
Author(s):  
Suelen Rocha Silva ◽  
Adriana Rahal Rebouças de Carvalho
Keyword(s):  
General Population ◽  
Outpatient Clinic ◽  
Sao Paulo ◽  
São Paulo ◽  
Significant Difference ◽  
The Mean ◽  
Lingual Frenum ◽  
Tongue Mobility ◽  
Tip Of The Tongue

Introdução: A qualidade de uma voz depende da fonte produtora e do filtro. Características da voz devem estar adequadas como, por exemplo, a ação da fonte com o filtro e a frequência, pois se estiverem alteradas e se essa voz for utilizada de forma inadequada, pode causar várias alterações vocais, que são chamadas de disfonias comportamentais. Essas disfonias ocorrem por conta do mau uso ou abuso vocal. Objetivo: Verificar se há maior prevalência de alterações de frênulo de língua em cantores com disfonia comportamental atendidos no Ambulatório de Artes Vocais da Santa Casa de São Paulo quando comparados a população. Método: participaram 18 cantores com idades entre 18 e 40 anos e 11 meses, de ambos os sexos que possuíam diagnóstico de disfonia comportamental e 23 indivíduos da população geral, da mesma faixa etária sem queixa de disfonia. A presença da disfonia comportamental foi verificada após análise do prontuário do Ambulatório de Artes Vocais da Santa Casa de São Paulo. Os dois grupos foram submetidos a avaliação clínica do frênulo de língua por meio de protocolo descrito por Marchesan (2010). Resultados: a média de idade dos cantores foi de 35,4 anos e da população geral de 26,57 anos. As medidas realizadas com paquímetro com a boca aberta e com a ponta da língua na papila palatina geram uma média que auxilia na avaliação do frênulo de língua. Em nosso estudo, 63,8% dos cantores e 71,1% da população geral apresentaram média superior a 50%, o que é considerado normal. As alterações apresentadas nos dois grupos foram: 5 cantores e 6 indivíduos da população geral apresentaram alteração nas provas de mobilidade de língua, 2 cantores e 9 indivíduos da população geral apresentaram alguma alteração em relação a praxia de língua e quanto a alteração de frênulo de língua, 5 cantores e 6 indivíduos da população geral apresentaram alguma alteração. Conclusão: Não houve diferença significativa entre os dois grupos nos aspectos avaliados. Desta maneira, não podemos concluir que há maior prevalência de alteração de frênulo de língua no grupo de cantores. Palavras chave: Frênulo da língua, Disfonia, Voz, PrevalênciaABSTRACT Introduction: The quality of a voice depends on the producing source and the filter. Voice characteristics must be appropriate, such as the action of the source with the filter and the frequency, because if they are altered and if this voice is used inappropriately, it can cause various vocal alterations, which are called behavioral dysphonias. These dysphonias occur because of vocal misuse or abuse. Objective: to verify if there is a higher prevalence of tongue frenulum alterations in singers with behavioral dysphonia seen at the Vocal Arts Outpatient Clinic of Santa Casa de São Paulo when compared to the general population. Method: 18 singers aged 18-40 years and 11 months, of both sexes who were diagnosed with behavioral dysphonia, after analysis of the medical records of the Vocal Arts Outpatient Clinic of Santa Casa de Sao Paulo and 23 individuals from the general population in the same age group without complaints of dysphonia. Both groups underwent clinical evaluation of the tongue frenulum using the protocol described by Marchesan (2010). Results: the mean age of the singers was 35.4 years and the mean age of the general population was 26.57 years. The measurements taken with a pachymeter with an open mouth and with the tip of the tongue on the palatal papilla generate an average that assists in the assessment of the tongue frenulum. In our study, 63.8% of singers and 71.1% of the general population had an average greater than 50%, which is considered normal. The alterations seen in both groups were: 5 singers and 6 individuals from the general population had altered tongue mobility tests; 2 singers and 9 individuals from the general population had some alteration in relation to tongue praxis, and as for tongue frenulum alterations, 5 singers and 6 individuals from the general population had some alteration. Conclusion: There was no significant difference between the two groups in all the aspects evaluated. Thus, we cannot conclude that there is a higher prevalence of tongue frenulum alteration in the group of singers. Keywords: Lingual frenum, Dysphonia, Voice, Prevalence

scholarly journals Occurrence of dolichocolon without megacolon in chronic Chagas disease patients

2012 ◽  
Vol 45 (3) ◽  
pp. 353-356 ◽  
Author(s):  
Cleudson Castro ◽  
Esperanza Bernal Hernandez ◽  
Joffre Rezende ◽  
Aluizio Prata
Keyword(s):  
Chagas Disease ◽  
Iliac Crest ◽  
Distal Colon ◽  
Clinical Findings ◽  
Central Axis ◽  
Female Patients ◽  
Male Patients ◽  
The Mean ◽  
Endemic Areas ◽  
Chronic Chagas Disease

INTRODUCTION: Since 1970, lengthening of the rectosigmoid has been suspected to be a solitary manifestation of Chagas colopathy. METHODS: To test this hypothesis, opaque enema was administered on 210 seropositive and 63 seronegative patients, and radiographs in the anteroposterior and posteroanterior positions were examined blind to the serological and clinical findings. The distal colon was measured using a flexible ruler along the central axis of the image from the anus to the iliac crest. RESULTS: Dolichocolon was diagnosed in 31 (14.8%) seropositive and 3 (4.8%) seronegative patients. The mean length was 57.2 (±12.2)cm in seropositive patients and 52.1 (±8.8)cm in the seronegative patients (p = 0.000), that is, the distal colon in Chagas patients was, on average, 5.1cm longer. Seropositive female patients presented a mean length of 58.8 (±12.3)cm, and seronegative female patients presented 53.2 (±9.1)cm (p = 0.002). Seropositive male patients had a mean length of 55 (±11.6)cm, and seronegative male patients had 49.9 (±7.8)cm (p = 0.02). Among 191 patients without megacolon and suspected megacolon, the mean length was 56.3 (±11.6)cm in seropositive individuals and 52 (±8.8)cm in seronegative patients (p = 0.003). Among individuals with distal colon >70cm, there were 31 Chagas patients with mean length of 77.9 (±7.1)cm and three seronegative with 71.3 (±1.1)cm (p = 0.000). Among 179 with distal colon <70cm, seropositive individuals had a mean length of 53.6 (±8.8)cm, and seronegative patients had 51.2 (±7.8)cm (p = 0.059). Serological positive women had longer distal colon than men (p = 0.02), whereas the mean length were the same among seronegative individuals (p = 0.16). CONCLUSIONS: In endemic areas of Brazil Central, solitary dolichocolon is a radiological Chagas disease signal.

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