scholarly journals Performance of pacu juveniles fed diets supplemented with L-carnitine

Author(s):  
Evandro Bilha Moro ◽  
Ricácio Luan Marques Gomes ◽  
Mariana Lins Rodrigues ◽  
Milena Souza dos Santos Sanchez ◽  
Fabio Bittencourt ◽  
...  

Abstract: The objective of this work was to determine the effect of L-carnitine supplementation on the productive performance and physiology of juvenile pacu (Piaractus mesopotamicus). A total of 288 pacu, with an initial average weight of 9.62±0.74 g, were fed experimental diets supplemented with 400, 800, 1,200, 1,600, and 2,000 mg kg-1 L-carnitine and a control diet (without supplementation), for 128 days. The following were evaluated: growth performance; carcass centesimal composition; intestinal, muscle, and hepatic histomorphologies; and oxidative stress. The fish hepatosomatic and viscerosomatic fat indexes increased with the inclusion of L-carnitine in the diets. The evaluation of carcass centesimal composition showed that the diets supplemented with 2,000 mg kg-1 L-carnitine caused a reduction in protein content and an increase in that of ethereal extract. Intestinal histomorphology indicated changes in the villi with L-carnitine supplementation. Moreover, hepatic lipid peroxidation occurred with the inclusion of 2,000 mg kg-1 L-carnitine. The supplementation with L-carnitine in the diets of pacu juveniles does not influence the development of the fish until the rate of 1,600 mg kg-1. However, high carcass lipid levels, as well as an increase in the hepatosomatic and viscerosomatic fat indexes, are observed in fish fed diets containing 2,000 mg kg-1.

2020 ◽  
Vol 48 (4) ◽  
pp. 674-685
Author(s):  
Uriel Rodríguez-Estrada ◽  
Otilio Méndez-Marín ◽  
Alfredo Pérez-Morales ◽  
Rafael Martínez-García ◽  
Emyr Peña-Marín ◽  
...  

This research study is focused on the lipid requirements of Petenia splendida (0.65 ± 0.19 g) juveniles. Fish were fed with trout commercial diet (Silver Cup™ - 45% protein and 16% lipids), as control diet - CD (which is usually used to feed this species at commercial scale), and four isoproteic (45% crude protein) diet formulated with different lipid levels (5, 10, 15 and 20%). Diets were administered for 60 days by triplicate per treatment. Our results showed that fish fed with 10, 15 and 20% lipid levels were significantly higher (P < 0.05) in average weight and total length. Same treatments were significantly lower (P < 0.05) in terms of FCR compared to those shown in 5% and CD. However, fish fed 20% lipid level, showed a significant decrease in WG and a significant (P < 0.05) increase in FCR compared to those shown in 15% lipid level. Fish fed with 15% showed the highest weight gain and the lowest FCR compared with the rest of the treatments. Lipid efficiency ratio (LER) showed significant (P < 0.05) differences among experimental groups. Compared to other diets containing lipid levels (5, 10, and 20%) fish fed 15% diet recorded the lowest protein and lipid content in whole body. Additionally, based on second order polynomial regression analysis of WG, it was demonstrated that 16.2% lipid provides an optimal growth for P. splendida.


Foods ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2202
Author(s):  
Micaelle Oliveira de Luna Freire ◽  
Luciana Caroline Paulino do Nascimento ◽  
Kataryne Árabe Rimá de Oliveira ◽  
Alisson Macário de Oliveira ◽  
Thiago Henrique Napoleão ◽  
...  

High-fat diet (HFD) consumption has been linked to dyslipidemia, low-grade inflammation and oxidative stress. This study investigated the effects of a mixed formulation with Limosilactobacillusfermentum 139, L. fermentum 263 and L. fermentum 296 on cardiometabolic parameters, fecal short-chain fatty acid (SCFA) contents and biomarkers of inflammation and oxidative stress in colon and heart tissues of male rats fed an HFD. Male Wistar rats were grouped into control diet (CTL, n = 6), HFD (n = 6) and HFD with L. fermentum formulation (HFD-Lf, n = 6) groups. The L.fermentum formulation (1 × 109 CFU/mL of each strain) was administered twice a day for 4 weeks. After a 4-week follow-up, biochemical parameters, fecal SCFA, cytokines and oxidative stress variables were evaluated. HFD consumption caused hyperlipidemia, hyperglycemia, low-grade inflammation, reduced fecal acetate and propionate contents and increased biomarkers of oxidative stress in colon and heart tissues when compared to the CTL group. Rats receiving the L. fermentum formulation had reduced hyperlipidemia and hyperglycemia, but similar SCFA contents in comparison with the HFD group (p < 0.05). Rats receiving the L. fermentum formulation had increased antioxidant capacity throughout the colon and heart tissues when compared with the control group. Administration of a mixed L. fermentum formulation prevented hyperlipidemia, inflammation and oxidative stress in colon and heart tissues induced by HFD consumption.


2020 ◽  
Vol 23 (2) ◽  
pp. 101-116
Author(s):  
Saracila Mihaela ◽  
Panaite Tatiana Dumitra ◽  
Papuc Camelia Puia ◽  
Predescu Corina Nicoleta ◽  
Untea Arabela

Abstract During two feeding trials, the effect of dietary phytogenic mixture on the performance and oxidative stress biomarkers in the liver of broilers reared under thermoneutral conditions (TN) and heat stress (HS) was studied. A number of 60 Cobb 500 chicks/trial were sheltered in environmentally-controlled digestibility cages. On the 14 days of age, the chicks were weighted and assigned to four groups (2 groups/trial with 30 chicks/group). In the first trial, two groups (C-TN and PM-TN) were kept in thermoneutral conditions. In the second trial, other two groups were kept (C-HS and PM-HS) in heat stress (32 ±1 °C). The structure of diets was the same in both experiments. Compared with the control diet (C), the experimental diet (PM) contained the addition of 1% phytogenic mixture (bilberry leaves, peppermint leaves, fennel leaves and sea buckthorn meal). Irrespective of temperature conditions, dietary PM did not affect broiler’s performance. The dietary supplementation of PM delayed protein and lipid oxidation in the liver tissue of broilers in both trials by increasing the hepatic catalase, glutathione and superoxide dismutase activity.


Author(s):  
Shiv Vardan Singh ◽  
Atul Shrivastava ◽  
Jyotshna ◽  
Upma Chaturvedi ◽  
Subhash Chandra Singh ◽  
...  

AbstractHyperlipidemia was induced by a single intraperitoneal dose of Triton WR-1339 in Charles Foster rats. The plasma lipid levels were estimated in control and treated groups. The antioxidant potential ofTheThese finding suggest that


Antioxidants ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 952
Author(s):  
Genea Edwards ◽  
Yonghoon Lee ◽  
Martha Kim ◽  
Soham Bhanvadia ◽  
Keun-Young Kim ◽  
...  

Oxidative stress is one of major causal factors in glaucomatous neurodegeneration. Ubiquinol promotes retinal ganglion cell (RGC) survival against glaucomatous insults such as oxidative stress. Here we investigated the effect of ubiquinol on RGC survival and/or visual function in mouse models of glaucoma and oxidative stress. DBA/2J and age-matched DBA/2J-Gpnmb+ (D2-Gpnmb+), which do not develop intraocular pressure elevation, or C57BL/6J mice were fed with ubiquinol (1%) or control diet daily for 5 or 2 months. We assessed RGC survival by Brn3a immunohistochemistry and measured expression levels of active and total BAX, peroxisome proliferator-activated receptor-gamma coactivator 1α, transcription factor A (TFAM) and oxidative phosphorylation (OXPHOS) complex protein. Following induction of oxidative stress by paraquat injection, we also assessed visual function. In glaucomatous retina, ubiquinol supplementation significantly promoted RGC survival, blocked BAX activation and increased TFAM and OXPHOS complex II protein expression. Also, ubiquinol supplementation ameliorated oxidative stress-induced visual dysfunction. These findings indicate that ubiquinol promotes RGC survival by increasing TFAM expression and OXPHOS complex II activity in glaucomatous neurodegeneration, and that ubiquinol enhances RGC survival and preserves visual function against oxidative stress. We propose that ubiquinol has a therapeutic potential for treating oxidative stress-associated glaucomatous neurodegeneration.


2019 ◽  
Vol 50 (10) ◽  
pp. 3017-3027 ◽  
Author(s):  
Daniel Pinto ◽  
Lucas Pellegrin ◽  
Lilian Fiori Nitz ◽  
Sílvio Teixeira da Costa ◽  
José Maria Monserrat ◽  
...  

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 525-526 ◽  
Author(s):  
T. G. Ramsay ◽  
M. J. Stoll ◽  
L. A. Blomberg ◽  
T. J. Caperna

2010 ◽  
Vol 80 (2) ◽  
pp. 97-106 ◽  
Author(s):  
Jae Soon Byun ◽  
Young Sun Han ◽  
Sang Sun Lee

Soy isoflavones have been reported to decrease the risk of atherosclerosis in postmenopausal women. However, the effects of dietary consumption of soybean have not been explored. In this study, we evaluated the effects of consuming yellow soybeans, black soybeans (Glycine max), or sword beans (Canavalia gladiate) on lipid and oxidative stress levels in an ovariectomized rat model. Forty-seven nine-week-old female rats were ovariectomized, randomly divided into four groups, and fed one of the following diets for 10 weeks: a diet supplemented with casein (NC, n = 12), a diet supplemented with yellow soybean (YS, n = 12), a diet supplemented with black soybean (BS, n = 12), or a diet supplemented with sword bean (SB, n = 11). Plasma triglyceride (TG) levels in the BS and SB groups were significantly lower than that in the NC group. Notably, the BS group had significantly lower plasma total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) levels than the other groups. Hepatic total lipid levels were significantly lower in the YS and SB groups, and cholesterol levels were significantly lower in the SB group than in the NC group. Superoxide dismutase (SOD) and catalase (CAT) activities were significantly higher in the groups fed beans compared to the NC group. Hepatic thiobarbituric acid reactive substances (TBARS) levels were also significantly lower in the BS and SB groups than the NC group. In conclusion, our results suggest that consumption of various types of beans may inhibit oxidative stress in postmenopausal women by increasing antioxidant activity and improving lipid profiles. Notably, intake of black soybean resulted in the greatest improvement in risk factors associated with cardiovascular disease.


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