Stimulation of body weight gain of the mature female rat by bovine GH and bovine placental lactogen

1991 ◽  
Vol 130 (1) ◽  
pp. 11-19 ◽  
Author(s):  
J. C. Byatt ◽  
N. R. Staten ◽  
J. J. Schmuke ◽  
F. C. Buonomo ◽  
S. S. Galosy ◽  
...  
Keyword(s):  
Weight Gain ◽  
Body Weight Gain ◽  
Mature Female ◽  
Female Rats ◽  
Placental Lactogen ◽  
Feed Consumption ◽  
Female Rat ◽  
Binding Studies ◽  
Response Curves ◽  
Igf I

ABSTRACT Mature female rats (200 g) were treated for 10 days with either recombinant bovine GH (bGH) or recombinant bovine placental lactogen (bPL) to compare the somatogenic responses elicited by these hormones. The treatments were administered by daily s.c. injection at four dose levels (0·19, 0·56, 1·67 and 5·0 mg/day). Both bGH and bPL stimulated significant increases in weight gain, but the slopes of the dose–response curves were different (P<0·05). Bovine PL was more potent than bGH (P<0·01) at the lowest dose, although there were no differences between treatment groups at the three higher doses. Feed consumption was stimulated more by bPL than bGH at all doses (P<0·001). The concentration of insulin-like growth factor-I (IGF-I) in blood plasma was increased by bGH in a dose-responsive manner and was higher than control at doses of 1·67 and 5 mg/day (P<0·05). Low doses of bPL stimulated increases in IGF-I similar to those with bGH. At the highest dose of bPL, however, there was no concomitant increase in plasma IGF-I. Nevertheless, the growth rate of the animals in this group matched that of the group given the highest dose of bGH. Receptor binding studies indicated that bPL bound to both GH and prolactin receptors. This is consistent with the growth data which suggest that bPL stimulated weight gain through a somatogenic mechanism as well as by another route, possibly mediated by lactogenic receptors. Journal of Endocrinology (1991) 130, 11–19

Stimulation of food intake and weight gain in mature female rats by bovine prolactin and bovine growth hormone

1993 ◽  
Vol 264 (6) ◽  
pp. E986-E992 ◽  
Author(s):  
J. C. Byatt ◽  
N. R. Staten ◽  
W. J. Salsgiver ◽  
J. G. Kostelc ◽  
R. J. Collier
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Weight Gain ◽  
Food Intake ◽  
Body Weight Gain ◽  
Mature Female ◽  
Female Rats ◽  
Bovine Growth Hormone ◽  
Female Rat ◽  
Moisture Percentage

Recombinant bovine prolactin (rbPRL) or bovine growth hormone (rbGH) was administered to mature female rats (10/treatment group) by daily subcutaneous injection for 10 days. Doses ranged from 7 to 5,000 micrograms/day (0.03-24 mg/kg body wt). Both rbPRL and rbGH increased body weight gain and food intake, but these parameters were increased at lower doses of rbPRL (7-63 micrograms/day) than rbGH (> 190 micrograms/day). Weight gain and food intake were maximally stimulated by 190 micrograms/day rbPRL, whereas maximal increased weight gain was obtained with the highest dose of rbGH (5,000 micrograms/day). Total carcass protein was increased by both hormones; however, protein as a percentage of body weight was unchanged. Similarly, neither rbPRL nor rbGH changed the percentage of carcass moisture. Percentage of body fat was increased by rbPRL but was decreased by rbGH. Weight of the gastrointestinal tract and kidneys was increased by both hormones, but increases were in proportion to body weight gain. These data confirm that ungulate prolactin is a hyperphagic agent in the female rat. In addition, they suggest that, while prolactin stimulates growth in mature female rats, this growth is probably not via a somatogenic mechanism.

Induction of growth hormone (GH) mRNA by pulsatile GH-releasing hormone in rats is pattern specific

2000 ◽  
Vol 278 (5) ◽  
pp. E885-E891 ◽  
Author(s):  
Russell J. Borski ◽  
Wellington Tsai ◽  
Roberta Demott-Friberg ◽  
Ariel L. Barkan
Keyword(s):  
Growth Hormone ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Somatic Growth ◽  
Pulse Amplitude ◽  
Female Rats ◽  
Mrna Levels ◽  
Female Rat ◽  
Constant Frequency ◽  
Releasing Hormone

Growth hormone-releasing hormone (GHRH) is a main inducer of growth hormone (GH) pulses in most species studied to date. There is no information regarding the pattern of GHRH secretion as a regulator of GH gene expression. We investigated the roles of the parameters of exogenous GHRH administration (frequency, amplitude, and total amount) upon induction of pituitary GH mRNA, GH content, and somatic growth in the female rat. Continuous GHRH infusions were ineffective in altering GH mRNA levels, GH stores, or weight gain. Changing GHRH pulse amplitude between 4, 8, and 16 μg/kg at a constant frequency (Q3.0 h) was only moderately effective in augmenting GH mRNA levels, whereas the 8 μg/kg and 16 μg/kg dosages stimulated weight gain by as much as 60%. When given at a 1.5-h frequency, GHRH doubled the amount of GH mRNA, elevated pituitary GH stores, and stimulated body weight gain. In the rat model, pulsatile but not continuous GHRH administration is effective in inducing pituitary GH mRNA and GH content as well as somatic growth. These studies suggest that the greater growth rate, pituitary mRNA levels, and GH stores seen in male compared with female rats are likely mediated, in part, by the endogenous episodic GHRH secretory pattern present in males.

Tamarind Seed Polysaccharide

2013 ◽  
Vol 32 (3) ◽  
pp. 198-208 ◽  
Author(s):  
James T. Heimbach ◽  
Hiroshi Egawa ◽  
Palma Ann Marone ◽  
Mark R. Bauter ◽  
Elke Kennepohl
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Food Consumption ◽  
Body Weight Gain ◽  
Clinical Chemistry ◽  
Clinical Signs ◽  
Female Rats ◽  
Feed Consumption ◽  
Test Substance ◽  
Tamarind Seed

Forty male and 40 female Crl:SD® CD® IGS rats were fed diets containing 0, 40 000, 80 000, or 120 000 ppm tamarind seed polysaccharide (equivalent to 3450.8, 6738.9, or 10 597.1 mg/kg bw/day and 3602.1, 7190.1, or 10 690.7 mg/kg bw/day for males and females, respectively) for 28 days. Animals were observed for adverse clinical signs, body weight, feed consumption, hematology and clinical chemistry parameters, urinalysis values were recorded, and at the end of the study the rats underwent a full necropsy. Functional Observational Battery (FOB) and Motor Activity (MA) tests were performed on all animals. There were no mortalities, no clinical or ophthalmologic signs, body weight, body weight gain, food consumption and food efficiency, FOB or MA findings associated with the administration of tamarind seed polysaccharide. Initial statistically significant decreases in body weight gain and food consumption resolved after the first week and were considered the result of reduced palatability. There were no adverse changes in hematology, coagulation, clinical chemistry or urinalysis parameters in male or female rats considered the result of test substance administration. At necropsy, there were no macroscopic, histopathological findings, estrus cycle, or organ weight changes deemed related to administration of the test substance. Under the conditions of this study and based on the toxicological endpoints evaluated, the no-observed-adverse-effect level (NOAEL) for tamarind seed polysaccharide in the diet was the highest concentration tested of 120 000 ppm (equivalent to 10 597 mg/kg bw/day and 10 691 mg/kg bw/day for male and female rats, respectively).

Effects of constant infusion with insulin-like growth factor-I (IGF-I) to immature female rats on body weight gain, tissue growth, and sexual function

Endocrine ◽  
1997 ◽  
Vol 6 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Nadine M. Gruaz ◽  
Violaine d'Allèves ◽  
Yves Charnay ◽  
Anna Skotther ◽  
Sven Ekvärn ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Growth Factor ◽  
Body Weight Gain ◽  
Tissue Growth ◽  
Female Rats ◽  
Constant Infusion ◽  
Immature Female ◽  
Factor I ◽  
Igf I

scholarly journals The Effects of Feed Color on Broiler Performance between Day 1 and 21

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1511
Author(s):  
Joseph P. Gulizia ◽  
Kevin M. Downs
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Treatment Effects ◽  
Body Weight Gain ◽  
Experimental Period ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Broiler Performance ◽  
Average Body ◽  
Average Body Weight

Two trials were conducted to determine feed color effects on broiler performance. A completely randomized design was used. Trial 1 included four treatments: control (complete broiler starter diet), red, green, and blue; and Trial 2 included four treatments: control, orange, yellow, and purple. Each trial had 4 treatments with 4 replicates (60 birds/treatment) fed to 240 male Cobb 500 broilers during a 21 d grow out. Data were analyzed using the GLM procedure. In Trial 1, there were no treatment effects on average body weight, body weight gain, and feed consumption (p > 0.05). Adjusted feed conversion for control (1.23) was less than red (1.27; p = 0.001) and green (1.26; p = 0.009), with blue (1.25; p = 0.056) tending to be different during the experimental period. In Trial 2, there were no treatment effects on average body weight, feed consumption, and adjusted feed conversion during this study (p > 0.05). Body weight gain between d 1 to 14 for purple (490.78 g/bird) was more than orange (467 g/bird; p = 0.013) and yellow (461 g/bird; p= 0.004), with control (474 g/bird; p = 0.052) tending to be different. Results indicate that these feed colors had some, albeit limited, influence on broiler performance parameters.

Differences in binge-like eating patterns of a palatable dessert and body weight gain in young and old female rats.

Appetite ◽  
2007 ◽  
Vol 49 (1) ◽  
pp. 312
Author(s):  
C.M. Mathes ◽  
M. Ferrara ◽  
N.E. Rowland
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Female Rats ◽  
Eating Patterns

scholarly journals PENGARUH BUNGKIL INTI SAWIT FERMENTASI DALAM PAKAN TERHADAP PERTUMBUHAN IKAN MAS ( Cyprinus carpio L.)

2017 ◽  
Vol 9 (1) ◽  
pp. 71-76 ◽  
Author(s):  
M. Amri
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Cyprinus Carpio ◽  
Body Weight Gain ◽  
Palm Kernel ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Good Level ◽  
Feed Cost ◽  
Fermentation Technology

The study effect of Fermented Palm Kernel Cage (FPKC) in feed on growth of Cyprinus carpio L. was done to evaluate the utilization of palm kernel cage increasing the quality by fermentation technology as a feed in ration to Cyprinus carpio L. performance and get a good level in ration. This experiment was set in a Randomized Completely Design with four treatments and four replicates.  Treatments were diets with : A (12% PKC), B (15% FPKC),  C (18% FPKC), and D (21% FPKC). Results of experiment indicated that the feed consumption body weight gain, feed conversion and income over feed cost was in proved by 18% FPKC in the diet.

scholarly journals Utilitas Asam Organik Sari Belimbing Wuluh dan Asam Sitrat Sintetis Sebagai Acidifier Terhadap Performa Produksi Puyuh (Coturnix coturnix Japonica) Fase Grower

2020 ◽  
Vol 7 (2) ◽  
pp. 133
Author(s):  
Hamdan Has ◽  
Astriana Napirah ◽  
Widhi Kurniawan ◽  
La Ode Nafiu ◽  
Takdir Saili
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Citric Acid ◽  
Body Weight Gain ◽  
Coturnix Japonica ◽  
Feed Consumption ◽  
Coturnix Coturnix Japonica ◽  
Feed Conversion ◽  
Coturnix Coturnix ◽  
Randomized Design

ABSTRAKPenggunaan acidifier baik organik atau sintetis dapat meningkatkan optimalisasi nutrien di dalam saluran pencernaan.  Optimalisasi nutrien diharapkan dapat meningkatkan performa ternak khususnya puyuh. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan dua macam acidifier terhadap performa puyuh fase grower. 100 ekor unsexed puyuh (Coturnix coturnix Japonica) fase grower umur 14-40 hari digunakan dalam penelitian yang menggunakan rancangan acak lengkap dengan lima perlakuan dan empat ulangan. Bahan pakan yang digunakan adalah jagung kuning, dedak, konsentrat puyuh komersil, sari belimbing wuluh, dan asam sitrat sintetis. Perlakuan yang dicobakan terdiri dari perlakuan kontrol (P0), penggunaan 0,3% asam sitrat sintetis (P1), penggunaan 0,25% sari belimbing wuluh (P2), penggunaan 0,6% asam sitrat sintetis (P3), dan penggunaan 0,5% sari belimbing wuluh (P4). Variabel yang diamati adalah konsumsi ransum, pertambahan bobot badan dan konversi ransum mingguan. Penggunaan sari belimbing wuluh memiliki konsumsi pakan yang lebih rendah  (P<0,05) pada minggu pertama dibanding kontrol dan asam sitrat sintetis.  Penggunaan asam sitrat sintetis meningkatkan pertambahan bobot badan pada minggu pertama (P<0,05). Penggunaan asam sitrat sintetis nyata dapat menurunkan konversi pakan minggu ke tiga dan empat dibanding kontrol dan asam organik belimbing wuluh. Kesimpulan penelitian ini yaitu penggunaan sari belimbing wuluh sebagai acidifier belum menunjukkan perbaikan performa yang signifikan sedangkan penggunaan asam sitrat sintetis memiliki performa yang lebih baik dibanding perlakuan kontrol dan penggunaan sari belimbing wuluh.Kata kunci: acidifier, asam sitrat, belimbing wuluh, puyuh fase growerABSTRACTThe organic and synthetic acidifiers could improve the optimization of nutrients utilization in the quail digestive tract. Furthermore, the optimization of nutrients is expected to improve quail performance. This study was aimed to determine the effect of using two types of acidifiers (Averrhoa bilimbi juice and synthetic citric acid) on the grower phase of quail performance. Total of 100 unsexed quails (Coturnix coturnix japonica) grower phase aged 14-40 days were used in this research and designed as a completely randomized design of five treatments and four replications. Feed ingredients used were yellow corn, rice bran, commercial quail concentrate, Averrhoa bilimbi juice (organic acidifier), and synthetic citric acid. The treatments consisted of control (P0), 0.3% synthetic citric acid (P1), use of 0.25% Averrhoa bilimbi juice (P2), use of 0.6% synthetic citric acid (P3), and use of 0.5% Averrhoa bilimbi juice (P4). The variables observed were weekly feed intake, body weight gain, and feed conversion. The result showed that utilization of Averrhoa bilimbi juice has lower feed consumption (P<0.05) in the first week compare to control and synthetic citric acid, and synthetic citric acid utilization increases body weight gain in the first week (P<0.05). The use of synthetic citric acid significantly reduces feed conversion in the third and fourth weeks compared to control and organic acid groups. The conclusion of this study is the utilization of Averrhoa bilimbi juice as an acidifier has not shown significant improvements in quail performance. The use of synthetic citric acid has a better performance compared to control and Averrhoa bilimbi juice utilization.Keywords: acidifier, organic acidifier, citric acid, growing quail

scholarly journals PENGARUH PENGGANTIAN JAGUNG DENGAN SORGUM Cv. KAWALI DALAM RANSUM PELLET TERHADAP PERFORMANS KELINCI LOKAL

ZOOTEC ◽  
2018 ◽  
Vol 39 (1) ◽  
pp. 42
Author(s):  
Agung R. P. Rumondor ◽  
B. Tulung ◽  
A. Rumambi ◽  
C.A Rahasia
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Analysis Of Variance ◽  
Body Weight Gain ◽  
Statistical Design ◽  
Feed Consumption ◽  
Feed Conversion ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
All Treatment

EFFECT OF REPLACEMENT OF CORN WITH SORGUM Cv. KAWALI IN PELLET RANSUM ON LOCAL RABBIT PERFORM. The purpose of this study was to determine the effect of substitution corn with sorghum in rabbit rations on feed consumption, body weight gain, and ration conversion. The duration of the study was 28 days using 20 local rabbits. The statistical design used in this study was a completely randomized design, with 4 (four) treatment rations and 5 (five) replications. The four experimental rations, namely R0: 45% corn + 0% sorghum, R1: 30% corn + 15% sorghum, R2 15% corn + 30% sorghum, R3 0% corn + 45% sorghum. Variables were measured, viz: feed consumption, body weight gain and ration conversion. The results showed that the average of feed consumption, body weight gain, and feed conversion, were: 28.27–30.59 g /head /day, 15.76–21.55 g / head /day, and 1.42-1.80 g /head /day, respectively. Based on the analysis of variance, the treatments ration had no significant effect (P> 0.05) on consumption, but had a very significant effect (P <0.01) on body weight gain and feed conversion. The LSD test showed that all treatment rations using sorghum (R1, R2, and R3) gave results of body weight gain which were very significantly different (P <0.01) and higher than R0. Whereas, on ration conversion, treatments R1, R2, and R3 give very different results (P <0.01) lower than R0. It is concluded that the substitution of corn with sorghum at the level of 45% in the ration gives the highest results for body weight gain and conversion of rations for rabbits. Keywords: corn, sorghum, ration, performance, local rabbit

Sign in / Sign up

Export Citation Format

Share Document