scholarly journals Orexins and the brain reinforcing systems

2020 ◽  
Vol 17 (4) ◽  
pp. 5-18
Author(s):  
Ilja Yu. Tissen ◽  
Andrei A. Lebedev ◽  
Eugenii R. Bychkov ◽  
Nikanor V. Lavrov ◽  
Vitalii I. Morozov ◽  
...  
Keyword(s):  
Positive Reinforcement ◽  
Emotional Memory ◽  
Special Role ◽  
Addictive Behaviors ◽  
Negative Experience ◽  
Brain Functions ◽  
History Of ◽  
Neurophysiological Mechanisms ◽  
And Behavior

The purpose of the review was to analyze the neurochemical and neurophysiological mechanisms of the orexin system and the role of orexin in body functions and behavior. The focus is on the participation of orexin in the mechanisms of reinforcement and the formation of addictive behavior. At the beginning of the review a history of the first works on the field of orexin and its receptors are described. Hypothalamic orexin-producing cells and effects on brain functions are described. The effects of orexins and their receptors on eating behavior, wakefulness and positive reinforcement are described. Then, the effects of orexins on narcolepsy was analyzed. The participation of orexins in the mechanisms of reinforcement and dependence and the key role of orexins in the development of addictive behaviors is described. The special role of orexin in the formation of ethanol dependence is shown. Next, the issue of the action of orexins under stress was considered. Orexins have been shown to play an important role in the regulation of the nervous and humoral mechanisms mediating the formation of emotional memory associated with negative experience. It is concluded that orexin can modulate the estimation of stress and probability for reaching stimulus. In this regard, orexin antagonists can be considered as possible promising means of preventing and treating disorders of the anxiety-phobic spectrum, as well as disorders associated with the use of addictive drugs caused by stress and environmental stimuli.

scholarly journals FEATURES OF JUDICIAL CASES INVOLVING WOMEN IN THE FATIMID CALIPHATE IN THE 10TH–12TH CENTURIES (historical and legal analysis)

2020 ◽  
pp. 249-253
Author(s):  
Faridun Z. Zavurbekov
Keyword(s):  
Legal Status ◽  
Negative Attitude ◽  
Special Role ◽  
Legal Analysis ◽  
Criminal Cases ◽  
Judicial Process ◽  
Judicial Practice ◽  
Marriage Contract ◽  
History Of

The article deals with the rights of women in the Fatimid Caliphate (10th to 12th centuries) by analysing the judicial practice of the time, the decisions of the Sharia and Mazalim courts. The author focuses on the legal status of women in the sphere of marriage, family and criminal law in the Ismaili tradition. Historical-legal and comparative-legal methods are used in the analysis of sources. The study begins with a short digression into the history of the Fatimid Caliphate. The features of the judicial system, the role of the cadi and its competence are described. There are a number of court cases, one of the parties to which was a woman. Based on the analysis, the author makes a conclusion about the specifi city of the Fatimid approach to marriage, in comparison with the Sunni and Imamite legal schools. The special role of guardians at the conclusion of the marriage contract and restriction of freedom of its termination is noted. Attention is drawn to the fact of extremely negative attitude to marriage between Muslim women and representatives of other religious movements, as well as to such an institution of family law as temporary marriage, legalised in the Imamite school of law. The fi nal part deals with criminal cases in which a woman is both the victim and the accused. Based on these precedents, it is a non-trivial conclusion that the judges of the Fatimid Caliphate did not always rely on Sharia norms when making decisions against women, which is completely atypical for Muslim traditions in general. At the same time, any crimes against this group of the population were punished rather severely. Particular attention is drawn to the state’s approach to women plaintiffs, depending on the degree of their personal participation in the judicial process.

scholarly journals Aplikasi Teori Behavioristik dan Konstruktifistik dalam Kegiatan Pembelajaran di Sekolah Tinggi Ilmu Tarbiyah Raden Wijaya Mojokerto

2017 ◽  
Vol 6 (2) ◽  
pp. 33
Author(s):  
Akhmad Pandu Setiawan
Keyword(s):  
Learning Theory ◽  
Positive Reinforcement ◽  
Cognitive Learning ◽  
Behavioral Changes ◽  
Negative Evaluation ◽  
Learning Approaches ◽  
The Road ◽  
And Behavior ◽  
Desirable Behavior

Behaviorism learning theory is oriented towards results that can be measured and observed. Repetition and training used so that the desired behavior can become a habit. The expected results of the implementation of this behavioristic theory is the formation of a desired behavior. The desirable behavior gets positive reinforcement and behavior that is not appropriate awarded the negative. Evaluation or assessment based on observed behavior. In theory this learned professor was not much give a lecture, but the brief instruction is followed by examples by themselves or through simulation. The purpose of this paper is to describe the application of the theory Behavioristic and konstruktifistik in learning activities at the School of Raden Wijaya Tarbiyah Mojokerto. Behavioristic learning theory emphasizes the changes in behavior as well as a result of the interaction between stimulus and response. Learning is a process of behavioral changes as a result of the interaction between stimulus and response. A person is considered to have learned if he could show changes in behavior. Although learning theory tigkah behavior began to be abandoned century, but collaborate on this theory with cognitive learning theory and the theory of other learning is essential for creating a learning approach that is appropriate and effective, because basically there is no single theory of learning that is truly suited to creating a learning approaches and effective fit. especially with constructivism learning model. The role of the faculty in constructivist learning very demanding mastery of a broad and in-depth about the material taught. A broad and deep knowledge allow a lecturer accept different views and ideas of students and also makes it possible to indicate whether or not the idea of ​​the road. Mastery of the material allows a professor to understand all kinds of roads and the model to arrive at a solution to the problem without fixed on one model.

Attitudes and Behavior

2020 ◽  
Author(s):  
Geoffrey Haddock ◽  
Sapphira Thorne ◽  
Lukas Wolf
Keyword(s):  
Primary Reason ◽  
Controlled Processes ◽  
Social Lives ◽  
History Of Research ◽  
History Of ◽  
Attitude Behavior ◽  
The Individual ◽  
And Behavior ◽  
Attitudes And Behavior

Attitudes refer to overall evaluations of people, groups, ideas, and other objects, reflecting whether individuals like or dislike them. Attitudes have been found to be good predictors of behavior, with generally medium-sized effects. The role of attitudes in guiding behavior may be the primary reason why people’s social lives often revolve around expressing and discussing their attitudes, and why social psychology researchers have spent decades examining attitudes. Two central questions in the study of attitudes concern when and how attitudes predict behavior. The “when” question has been addressed over decades of research that has identified circumstances under which attitudes are more or less likely to predict behavior. That is, attitudes are stronger predictors of behaviors when both constructs are assessed in a corresponding or matching way, when attitudes are stronger, and among certain individuals and in certain situations and domains. The “how” question concerns influential models in the attitudes literature that provide a better understanding of the processes through which attitudes are linked with behaviors. For instance, these models indicate that other constructs need to be taken into account in understanding the attitude-behavior link, including intentions to perform a behavior, whether individuals perceive themselves to be in control of their behavior, and what they believe others around them think the individual should do (i.e., norms). The models also describe whether attitudes relate to behavior through relatively deliberative and controlled processes or relatively automatic and spontaneous processes. Overall, the long history of research on attitude-behavior links has provided a clearer prediction of when attitudes are linked with behaviors and a better understanding of the processes underlying this link.

scholarly journals Present and future of Francophony, or Battle for French

2021 ◽  
pp. 41-48
Author(s):  
Marina N. Vetchinova ◽  
Keyword(s):  
English Language ◽  
Public Institutions ◽  
International Organization ◽  
French Language ◽  
Special Role ◽  
World Languages ◽  
The World ◽  
History Of ◽  
Other World

The article analyzes the place and role of the French language in the linguistic picture of the world, provides figures that characterize its position. The article shows the history of the creation and modern activities of the International Organization of Francophone Countries, as well as the history of the emergence of the term “Francophonie”, the angles of its use are noted. It contains data on the use of the French language on the African continent, and makes reasonable guesses about where it will occupy in Africa in the future. The article deals with the activities of the French state and international public institutions to popularize the French language in the world. It draws attention to initiatives to promote French. Information about the study of the French language in various countries is presented, the special role of teachers in its study is emphasized, the difficulties of competing with the English language are highlighted. Thanks to given mathematical calculations one can already assume an important role and significant place of French among other world languages in the middle of the XXI century.

scholarly journals Neurochemical mechanisms and pharmacology of ghrelins

2020 ◽  
Vol 18 (1) ◽  
pp. 5-22
Author(s):  
Petr D. Shabanov ◽  
Andrei A. Lebedev ◽  
Eugenii R. Bychkov ◽  
Nikanor V. Lavrov ◽  
Vitalii I. Morozov
Keyword(s):  
The Body ◽  
Molecular Forms ◽  
Pharmacological Agents ◽  
Ghrelin Receptor ◽  
Physiological Processes ◽  
History Of ◽  
Ghrelin Receptors ◽  
Neurophysiological Mechanisms ◽  
And Behavior ◽  
The Brain

The purpose of the review was to analyze the neurochemical and neurophysiological mechanisms of the ghrelin system and the role of ghrelin in body functions and behavior. The focus is on the participation of ghrelin in the mechanisms of reinforcement and the formation of addictive behavior. At the beginning of the review a history of the first works on the field of ghrelin and its receptor was described. Then, genetic control, molecular precursor of ghrelin, molecular forms of ghrelin and ghrelin receptor were represented. In particular, the distribution of the ghrelin receptor, ghrelin-producing cells in the brain and its participation in various physiological functions of the body were shown. The hypothalamic functions of ghrelin were discussed: energy balance, regulation of glucose metabolism, stimulation of eating behavior, regulation of hypophys-pituitary axis (HPA) system. The connection of ghrelin with the brain CRH system was demonstrated. In particular, activation of HPA was described as a possible mechanism through which ghrelin regulates a number of physiological processes. Extrahypothalamic action of ghrelin was shown on the basis of the mechanisms of reinforcement and addiction. On the basis of their own data and literary, it was concluded that action of alcohol and psychoactive drugs are reduced after the ghrelin receptors blockade. In particular, it has been demonstrated that alcoholization of mothers affects the activity of the ghrelin system during the prenatal and early postnatal periods of development in the offspring of rats. It was shown the participation of ghrelin in memory and learning. The further perspective of the study and practical application of ghrelin-based pharmacological agents was analyzed.

Relationship Connection: A Redux on the Role of Minding and the Quality of Feeling Special in the Enhancement of Closeness

2009 ◽  
pp. 384-392
Author(s):  
John H. Harvey ◽  
Brian G. Pauwels
Keyword(s):  
Behavior Patterns ◽  
Self Disclosure ◽  
Close Relationship ◽  
History Of ◽  
Future Direction ◽  
Ending Process ◽  
And Behavior ◽  
The Relationship

Achieving constructive relationship connections is an important step as an objective of positive psychology. In the context of a culture of dissolution in close relationships, minding serves as an antidote to the demise of feelings of closeness overtime. In this paper, we argue that minding the close relationship is a powerful pathway to developing and enhancing closeness. Minding is a combination of thought and behavior patterns that interact to create stability and feelings of closeness. Minding is formally defined as a reciprocal knowing process that occurs nonstop throughout the history of the relationship and that involves a complex package of interrelated thoughts, feelings, and behaviors. The components of minding are knowing and being known, achieved through reciprocal self-disclosure; attribution that is realistic about causality, but that also gives one's partner the benefit of doubt in questionable circumstances; acceptance of what one discovers in the knowing process and respect for one's partner revealed in this process; and reciprocity and continuity. The final component emphasizes the fact that minding must be done by both partners and that it is a never-ending process. The paper also describes other contemporary conceptions to which minding is closely related and addresses future direction for research on the minding process.

Per una storia dell'affidamento dei malati psichiatrici alle famiglie: Towards a history of the family care of psychiatric patients

2009 ◽  
Vol 18 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Patrizia Guarnieri
Keyword(s):  
Mental Health ◽  
Mentally Ill ◽  
Psychiatric Patients ◽  
Family Care ◽  
Special Role ◽  
The Past ◽  
The Family ◽  
History Of ◽  
Psychiatric Staff

SummaryInserting adults with psychic problems into families has recently been practiced in various European countries and also in Italy, where some mental health departments support such families. Beyond the well known story of Gheel, the etero and omofamily care of psychiatric patients has a forgotten history. Methods – On the basis of unexplored and exceptionally rich sources from the archives of the asylums in Florence, as well as of the Province di Florence, which funded assistance to the mentally ill – this research focuses on the subsidized “domestic custody” of hundreds of psychiatric patients, who had already been institutionalized. Beginning in 1866, outboarding was supported by the provincial administration in Florence with the collaboration of the asylum medical direction. Results – In the late 19th C. and in the early 20th C. prestigious psychiatrists sought alternatives to the institutionalisation. These alternatives involved varied participants in a community (the patients and their families, the administrators and the medical specialists, the neighborhood and the police). The families played a special role that historians of the psychiatry exclusively dedicated to the insane asylums have not really seen. Conclusions – The role of the families in the interaction with the psychiatric staff is not, even on a historiographical level, simply an additional and marginal chapter of the practices and of the culture of the mental health. These archival evidence contradicts some common places on the past of the Italian psychiatry before 1978, and provokes new reflections of possible relevance to the present.

scholarly journals Reward Network Modulation as a Mechanism of Change in Behavioral Activation

2018 ◽  
Vol 44 (2) ◽  
pp. 186-213 ◽  
Author(s):  
Gabriela A. Nagy ◽  
Paul Cernasov ◽  
Angela Pisoni ◽  
Erin Walsh ◽  
Gabriel S. Dichter ◽  
...  
Keyword(s):  
Positive Reinforcement ◽  
Behavioral Activation ◽  
American Psychological Association ◽  
Empirical Support ◽  
Psychosocial Treatment ◽  
Depression Symptoms ◽  
Third Wave ◽  
History Of ◽  
Reward Network ◽  
And Behavior

Behavioral Activation (BA) is a contemporary third-wave psychosocial treatment approach that emphasizes helping individuals become more active in ways that are meaningful to them as a means of improving mood and quality of life. BA has been designated as a well-established, validated treatment for depression by the American Psychological Association following several decades of accumulated empirical support demonstrating that BA techniques successfully reduce depression symptoms and produce other desirable outcomes across a variety of populations and contexts. The purported mechanism of change underlying BA treatment lies in increasing activation, which in turn increases contact with positive reinforcement thereby reversing the cycle of depression. Current studies are further investigating how increasing activation and subsequent contact with mood reinforcers can influence mood and behavior. Specifically, there is growing evidence that BA modifies function of reward-related networks in the brain, and that these changes are associated with clinical improvement. Herein, we provide a brief history of BA, describe the primary components of BA treatment, and describe BA’s purported mechanisms of change at behavioral, neural, and subjective activation levels. We present limitations as well as gaps in the current state of knowledge regarding mechanisms of action of BA.

scholarly journals Genetic recovery of ErbB4 in adulthood partially restores brain functions in null mice

2018 ◽  
Vol 115 (51) ◽  
pp. 13105-13110 ◽  
Author(s):  
Hongsheng Wang ◽  
Fang Liu ◽  
Wenbing Chen ◽  
Xiangdong Sun ◽  
Wanpeng Cui ◽  
...  
Keyword(s):  
Neural Development ◽  
Critical Role ◽  
Gaba Release ◽  
Brain Disorders ◽  
Gabaergic Transmission ◽  
Brain Functions ◽  
Adult Mice ◽  
Mutant Strains ◽  
And Behavior

Neurotrophic factor NRG1 and its receptor ErbB4 play a role in GABAergic circuit assembly during development. ErbB4 null mice possess fewer interneurons, have decreased GABA release, and show impaired behavior in various paradigms. In addition, NRG1 and ErbB4 have also been implicated in regulating GABAergic transmission and plasticity in matured brains. However, current ErbB4 mutant strains are unable to determine whether phenotypes in adult mutant mice result from abnormal neural development. This important question, a glaring gap in understanding NRG1–ErbB4 function, was addressed by using two strains of mice with temporal control of ErbB4 deletion and expression, respectively. We found that ErbB4 deletion in adult mice impaired behavior and GABA release but had no effect on neuron numbers and morphology. On the other hand, some deficits due to the ErbB4 null mutation during development were alleviated by restoring ErbB4 expression at the adult stage. Together, our results indicate a critical role of NRG1–ErbB4 signaling in GABAergic transmission and behavior in adulthood and suggest that restoring NRG1–ErbB4 signaling at the postdevelopmental stage might benefit relevant brain disorders.

The Emergence of Forest Genetics in Portugal

2017 ◽  
Vol 47 (1) ◽  
pp. 76-106
Author(s):  
Ignacio García-Pereda
Keyword(s):  
International Development ◽  
Cork Oak ◽  
Institution Building ◽  
Special Role ◽  
History Of Biology ◽  
Forest Genetics ◽  
Forestry Research ◽  
History Of ◽  
The One

This paper aims to contribute to a better understanding of the history of biology and forestry in Portugal. It will focus on the one state-owned cork oak station devoted to forestry research, showing how its foresters and scientists shaped, and relied on, the state-controlled unions, both for producing and distributing varieties of cork oak and for controlling the seeds and plants forest owners used. Portugal played a very special role in the international development of Mediterranean forest genetics during the first half of the twentieth century. Forestry genetics were decisive for the Estado Novo government, and the Alcobaça Station became a model for the future organization of other countries’ applied forestry research centers. The paper shows how the milieu of forestry scientists and breeders played an important role in the development and institutionalization of genetics in Portugal. The paper will explore how these relationships made it possible for the scientists to test, multiply, and distribute the seeds and plants they produced at the laboratory throughout the Portuguese landscape, thus demonstrating the role of scientists as active agents of state formation and landscape transformation within a corporate political economy. The history of the Alcobaça Forest Station is an important example of fascist institution building.

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