scholarly journals Albendazole therapy reduces serum zinc in elementary school children with Ascaris lumbricoides infections

2016 ◽  
Vol 35 (3) ◽  
pp. 206
Author(s):  
Ria Buana ◽  
Jane Florida Kalumpiu ◽  
Yenny Djuardi ◽  
Taniawati Supali
Keyword(s):  
Elementary School ◽  
School Children ◽  
Ascaris Lumbricoides ◽  
Elementary School Children ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
Absorption Spectrometry ◽  
Lower Serum ◽  
Serum Zinc Concentration ◽  
Zinc Concentrations

Background<br />Soil-transmitted helminth (STH) infection can cause malnutrition and vice versa, and decrease serum zinc concentrations. No previous studies were found on the effect of STH treatment on serum zinc concentrations in elementary school children. The objective of this study was to evalaute the effect of STH treatment on serum zinc concentration in elementary school children in Jakarta. <br /><br />Methods<br />A pre-experimental study (one group pre and post) was conducted on 3rd - 5th grade students in one elementary school in North Jakarta. FLOTAC examination was used to determine infection status and STH intensity, while serum zinc concentrations were measured by atomic absorption spectrometry. All children were given albendazole 400 mg for three consecutive days. Stool and blood samples were collected before and three weeks after treatment with albendazole. A paired t test was used to analyze the data. <br /><br />Results<br />The STH prevalence was 63.4%; these were mainly Ascaris lumbricoides and Trichuris trichiura infections. Before treatment, children infected with A.lumbricoides and T.trichiura had significantly higher serum zinc concentrations (p=0.028; p=0.014). After treatment, children with A.lumbricoides had significantly lower serum zinc concentrations (p=0.039), while children with T.trichiura had slightly lower serum zinc concentrations (p=0.659) than before treatment. <br /><br />Conclusions<br />Albendazole treatment produces lower serum zinc concentration in elementary school children with A.lumbricoides infections. A profound understanding of the interaction between helminth infections and zinc may assist in guiding integrated and sustainable intervention strategies among affected children throughout the world.

scholarly journals HUBUNGAN INFEKSI SOIL TRANSMITTED HELMINTH DENGAN KADAR HEMOBGLOBIN ANAK SEKOLAH DASAR GMIM BUHA MANADO

e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Muhammad Fachrurrozy Basalamah ◽  
Viviekenanda Pateda ◽  
Novie Rampengan
Keyword(s):  
Elementary School ◽  
School Children ◽  
Ascaris Lumbricoides ◽  
Elementary School Children ◽  
Hemoglobin Concentration ◽  
Trichuris Trichiura ◽  
Cross Sectional ◽  
Necator Americanus ◽  
Ancylostoma Duodenale ◽  
Relationship Of

Abtract: Intestinal worm infections are transmitted via soil (soil-transmitted helminth) is a global problem, especially in developing countries. The main worm infections caused by Ascaris lumbricoides, Trichuris trichiura, and hookworm (necator americanus and Ancylostoma duodenale). Worm infections affect the digestion, absorption, and metabolism of food could result in loss of protein, carbohydrates, fats, vitamins and large amounts of blood as well as lower mean hemoglobin concentration. The purpose of this study was to determine the relationship of helminth infection with hemoglobin levels of elementary school children GMIM Buha Manado. This research was an observational analytic cross-sectional approach. Sebjek study as many as 80 children. Results showed that children infected with worms very significant effect on levels of hemoglobin (p < 0.001). Children who are infected with worms had lower hemoglobin levels when compared with children who are not infected with the worm. Children who are infected with the worm hemoglobin level falls to 9.5 g/dl. Keywords: elementary school children - a worm infection - hemoglobin.   Abstrak: Infeksi cacing usus yang ditularkan melalui tanah (soil transmitted helminth) merupakan masalah dunia terutama di negara sedang berkembang. Infeksi cacing utama disebabkan oleh ascaris lumbricoides, trichuris trichiura, dan cacing tambang (necator americanus dan ancylostoma duodenale). Infeksi cacing berpengaruh terhadap pencernaan, penyerapan, serta metabolisme makanan yang dapat berakibat hilangnya protein, karbohidrat, lemak, vitamin dan darah dalam jumlah besar serta menurunkan konsentrasi hemoglobin rerata. Tujuan penelitian ini adalah untuk mengetahui hubungan infeksi cacing dengan kadar hemoglobin anak sekolah dasar GMIM Buha Manado. Jenis penelitian adalah observasional analitik dengan pendekatan cross sectional. Sebjek penelitian sebanyak 80 anak. Hasil penelitian menunjukkan bahwa anak-anak yang terinfeksi cacing berpengaruh sangat bermakna terhadap kadar hemoglobin (p < 0,001). Anak-anak yang terinfeksi cacing memiliki kadar hemoglobin lebih rendah bila dibandingkan dengan anak-anak yang tidak terinfeksi cacing. Anak-anak yang terinfeksi cacing kadar hemoglobinnya turun hingga mencapai 9,5 g/dl. Kata kunci: anak SD - infeksi cacing - kadar hemoglobin

scholarly journals PREVALENCE OF SOIL-TRANSMITTED HELMINTHIASIS AMONG ELEMENTARY CHILDREN IN SORONG DISTRICT, WEST PAPUA

2019 ◽  
Vol 7 (4) ◽  
pp. 86 ◽  
Author(s):  
Natalia Yuwono ◽  
Dominicus Husada ◽  
Sukmawati Basuki
Keyword(s):  
Elementary School ◽  
Elementary Schools ◽  
School Children ◽  
Ascaris Lumbricoides ◽  
Elementary School Children ◽  
Trichuris Trichiura ◽  
Primary School Children ◽  
Personal Hygiene ◽  
West Papua ◽  
Soil Transmitted Helminthiasis

Soil transmitted helminthiasis are common in the world and cause illness, especially in developing countries. It can cause infection in humans by contact with parasitic eggs or larvae that live in moist and warm soil. Soil-transmitted helminthiasis is often caused by Ascaris lumbricoides, Trichuris trichiura, Ancylostoma duodenale, and Necator americanus. In Indonesia, Soil transmitted helminthiasis prevalence is still high in some places. The tropical climate and high humidity support for the development of worms like in Sorong District, but there was no data. The purpose of this study is to identify the presece of Soil transmitted helminthiasis in primary school children in Sorong District. A cross-sectional study was conducted in two elementary schools located in Sorong District, West Papua, Indonesia. The two elementary schools are SDN 22 in Klain village and SD  Inpres 24 in sub-district Mayamuk. Once collected, the pot that has contained stool is given formalin 10%. Stool examinattion using direct smear method to determine the presence of soil transmitted helminthiasis. Researchers get the subject as many as 147 children. The proportion of elementary school children by sex consists of 72 boys (49%) and 75 girls (51%). The prevalence of Soil transmitted helminthiasis as a whole was 30.6% (45/147) with 40.1% (18/45) single infections and 59.9% (27/45) mixed infections. The single infection that most frequent is Trichuris trichiura, then followed by Ascaris lumbricoides. Soil-transmitted helminthiasis mostly found in girl than boy and mostly found in 6-9 years age group.  The worm species that infect elementary school children in the district is Ascaris lumbricoides, Trichuris trichiura, Hookworm, and Strongyloides stercoralis. This is probably related with the climate and low sanitation level. To eliminate soil transmitted helminthiasis among elementary school children, in addition to routine treatment also needs intensive counseling about the importance of maintaining personal hygiene and the environment.

Seasonal Variations of Serum Zinc Concentration in Adult Population: Tehran Lipid and Glucose Study

2020 ◽  
Author(s):  
Sahar ASKARI ◽  
Golaleh ASGHARI ◽  
Hossein FARHADNEJAD ◽  
Arash GHANBARIAN ◽  
Parvin MIRMIRAN ◽  
...  
Keyword(s):  
Seasonal Variations ◽  
Zinc Concentration ◽  
Adult Population ◽  
Geometric Mean ◽  
Serum Zinc ◽  
Seasonal Fluctuation ◽  
Serum Zinc Concentration ◽  
Four Seasons ◽  
Zinc Concentrations ◽  
General Populations

Background: Zinc, an essential trace element, plays a key role in many biological human body functions. Serum zinc concentration is the most widely used indicator of zinc status for general populations. Considering the limited data available on seasonal fluctuation of serum zinc concentration, we aimed at determining seasonal variations in serum zinc concentrations of Tehranian adults. Methods: The current study was conducted within the framework of the Tehran Lipid and Glucose Study, on 4698 subjects, aged ≥20 years. Serum zinc samples of subjects were obtained from all four seasons over three years (from 2009 to 2011); samples of similar seasons over three years were placed in one group and the geometric means of serum zinc concentration of four seasons were compared to determine possible seasonal variations. Results: Participants with mean age 46.3 yr and geometric mean of serum zinc concentration 116.3 µg/dl, were studied for almost three years through four seasons. Serum zinc concentrations in spring and summer were significantly higher than those in autumn and winter (112.2 and 114.4 vs. 106.7 and 104.8 µg/dl; P<0.001, respectively). Moreover, monthly serum zinc concentration of all subjects differed, with the lowest and highest levels found in October and August (98.5 vs. 122.7; P<0.001). Conclusion: This study demonstrates the difference in serum zinc concentration in Iranian adults of both genders in different months and seasons during the year.

scholarly journals High Prevalence of Zinc Deficiency in Rural Nigerian Preschool Children: A Community-Based Cross-Sectional Study

2017 ◽  
Vol 24 (1) ◽  
pp. 31-39
Author(s):  
Amarabia N.E. Ibeawuchi ◽  
Alphonsus N. Onyiriuka ◽  
Philip O. Abiodun
Keyword(s):  
Zinc Deficiency ◽  
Rural Community ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
Cross Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Serum Zinc Concentration ◽  
High Prevalence ◽  
Zinc Concentrations

AbstractBackground and Aims: In Nigeria, community-based epidemiological data related to the prevalence of zinc deficiency in preschool children are scarce. We assessed the prevalence of zinc deficiency and the associated socio-demographic variables in children aged between 6 and 60 months, living in a Nigerian rural community.Materials and Methods: In this cross-sectional study, the serum zinc concentrations of 252 children aged between 6 and 60 months in a rural community in Nigeria were assessed, using atomic absorption spectrophotometry. The study population was selected by multistage random sampling and at least two children were selected from every household which had children in the study age group. The socio-demographic characteristics of the subjects were obtained, using an interviewer-administered questionnaire.Results: A total of 252 children were studied, 134 (53.2%) males and 118 (46.8%) females. The mean age was 32.7±17.0 months, similar for both sexes. Overall, 220 (87.3%) had low serum zinc concentrations (less than 7.65µmol/L). According to age, the highest mean serum zinc concentration was 5.43±3.52µmol/L in children aged between 6 and 12 months. Correlation between serum zinc concentration and family size or socio-economic status (SES) showed that the smaller the family size and the higher the SES, the higher the serum zinc concentration.Conclusions: The high prevalence of low serum zinc concentration indicates that zinc deficiency is a public health problem in our rural communities, requiring public health intervention.

scholarly journals Comparative study of serum zinc concentrations in benign and malignant prostate disease: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jiang Zhao ◽  
Qingjian Wu ◽  
Xiaoyan Hu ◽  
Xingyou Dong ◽  
Liang Wang ◽  
...  
Keyword(s):  
Zinc Concentration ◽  
Meta Analysis ◽  
Serum Zinc ◽  
Cochrane Library ◽  
Prostatic Disease ◽  
Serum Zinc Concentration ◽  
Prostate Disease ◽  
Zinc Concentrations ◽  
The Relationship ◽  
Normal Controls

Abstract Many studies have investigated the relationship between serum zinc concentration and prostatic disease, but have shown inconsistent results. Hence, we performed a systematic literature review and meta-analysis to assess the correlation between serum zinc concentration and prostate disease. Systematic literature searches were conducted with PubMed, EMBASE, Science Direct/Elsevier, MEDLINE, CNKI and the Cochrane Library up to June 2015 for studies that involved the relationship between serum zinc concentration and prostate disease. Fourteen studies were identified from the databases. Our results illustrated that the serum zinc concentrations in prostate cancer patients were significantly lower than those in Benign prostatic hyperplasia (BPH) patients and normal controls (SMD (95% CI), −0.94 [−1.57, −0.32]; −1.18 [−1.90, −0.45]). However, the serum zinc concentrations in BPH patients were significantly higher than those in normal controls (SMD (95% CI) 1.77 [0.15, 3.39]). The present study showed that different levels of serum zinc concentrations are correlated with different prostatic disease. Serum zinc concentration may be used as a tool for the diagnosis and screening of prostate disease. But, further studies with well-designed larger sample studies are needed in this field to further clarify the correlation between serum zinc concentration and prostate disease.

scholarly journals Administration of zinc to preterm infants with hypozincemia does not reduce serum copper concentrations in most cases: a single-center retrospective observational study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Toshikazu Ito ◽  
Kazuya Uenoyama ◽  
Kazuhiro Kobayashi ◽  
Mikio Kakumoto ◽  
Hiroshi Mizumoto ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Zinc Acetate ◽  
Zinc Concentration ◽  
Zinc Acetate Dihydrate ◽  
Serum Zinc ◽  
Serum Copper ◽  
Acetate Dihydrate ◽  
Serum Zinc Concentration ◽  
Postmenstrual Age ◽  
Zinc Concentrations

Abstract Background Zinc is an essential trace element involved in various physiological functions. In Japan, zinc acetate dihydrate is administered to neonates and infants with hypozincemia. Since serum copper concentrations are reduced by the administration of zinc, we retrospectively investigated changes in serum zinc and copper concentrations in preterm infants with hypozincemia receiving zinc acetate dihydrate. Methods Sixty-three preterm infants were included in the present study. Serum zinc and copper concentrations, doses, and other clinical characteristics were retrieved from electronic medical records. Results The medians and interquartile ranges of the dosage and duration of zinc acetate dihydrate were 2.1 (1.8–2.5) mg/kg/day and 12.0 (10.0–13.0) days, respectively. Its administration increased serum zinc concentrations in 39 patients (61.9%) and to more than 70 μg/dL in 16 patients (25.4%). The group with a serum zinc concentration of 70 μg/dL or higher after administration had a significantly higher zinc dose of 2.5 mg/kg/day than the group with a serum zinc concentration of less than 70 μg/dL. Serum copper concentrations did not decrease in 44 patients (69.8%). In the group with a decreased serum copper concentration, postmenstrual age and body weight were significantly lower, while serum zinc concentrations were significantly higher at the start of administration. Conclusion The present results showed that when zinc acetate dihydrate was administered to preterm infants with hypozincemia, it was possible to increase serum zinc concentrations without decreasing serum copper concentrations in many cases. However, caution may be required when administering zinc to preterm infants with a lower postmenstrual age or milder hypozincemia because serum copper concentrations may decrease.

Effectiveness of micronutrient dietary intake and micronutrients fortifed milk to improve serum zinc concentrations of primary school children

2021 ◽  
Vol 30 (4) ◽  
pp. 67-74
Author(s):  
Tran Khanh Van ◽  
Tran Thuy Nga ◽  
Nguyen Xuan Hiep ◽  
Nguyen Song Tu ◽  
Nguyen Tran Ngoc Tu
Keyword(s):  
Dietary Intake ◽  
Primary School ◽  
School Children ◽  
Zinc Concentration ◽  
Serum Zinc ◽  
Primary School Children ◽  
Control Group ◽  
Fresh Milk ◽  
Zinc Concentrations ◽  
Reconstituted Milk

Micronutrient dietary intake of primary school children was evaluated at baseline survey. Then the randomized community intervention trial with pre- and post-intervention evaluation aims to evaluate effectiveness of micronutrient dietary intake and micronutrients fortified milk to improve serum zinc concentrations of primary school children. The two common types of milk on the market are fresh milk and reconstituted milk which were used as food vehicles to fortify 21 different vitamins and minerals and given to 2 groups of school children at a dose of 2 boxes of 180 ml/day, 7 day/ week for 6 months. Each group drank one kind of milk. Control group did not drink milk during the intervention. After the end of the intervention, serum zinc concentration in the two intervention groups improved significantly compared to the baseline (p <0.01). The serum zinc concentrations were increased by 0.65±3.13 μmol/L and 0.75±3.49 μmol/L in the group of drinking micronutrient fortified fresh milk and the group of drinking micronutrients fortified reconstituted milk, respectively Zinc concentration after 6 months and difference of zinc concentration between baseline and 6 months after intervention in intervened groups were improved significantly compared to those of the control group (p<0.05).

Lower Serum Zinc Concentration Despite Higher Dietary Zinc Intake in Athletes: A Systematic Review and Meta-analysis

2017 ◽  
Vol 48 (2) ◽  
pp. 327-336 ◽  
Author(s):  
Anna Chu ◽  
Cushla Holdaway ◽  
Trishala Varma ◽  
Peter Petocz ◽  
Samir Samman
Keyword(s):  
Systematic Review ◽  
Zinc Concentration ◽  
Meta Analysis ◽  
Serum Zinc ◽  
Dietary Zinc ◽  
Lower Serum ◽  
Zinc Intake ◽  
Serum Zinc Concentration

Use of Serum Zinc Concentration as an Indicator of Population Zinc Status

2007 ◽  
Vol 28 (3_suppl3) ◽  
pp. S403-S429 ◽  
Author(s):  
Sonja Y. Hess ◽  
Janet M. Peerson ◽  
Janet C. King ◽  
Kenneth H. Brown
Keyword(s):  
Zinc Deficiency ◽  
Zinc Concentration ◽  
Zinc Supplementation ◽  
Serum Zinc ◽  
Interindividual Variation ◽  
Zinc Status ◽  
Dietary Zinc ◽  
Serum Zinc Concentration ◽  
Zinc Concentrations ◽  
Intervention Trials

Assessing the prevalence and severity of zinc deficiency in populations is critical to determine the need for and appropriate targeting of zinc intervention programs and to assess their effectiveness for improving the health and well-being of high-risk populations. However, there is very little information on the zinc status of populations worldwide due to the lack of consensus on appropriate biochemical indicators of zinc status. The objective of this review was to evaluate the use of serum zinc concentration as an indicator of population zinc status. We have reviewed the response of serum zinc concentration to dietary zinc restriction and zinc supplementation. In addition, we completed pooled analyses of nine zinc intervention trials in young children to assess the relations between serum zinc concentration of individuals before treatment and their responses to zinc supplementation. Also, in updated combined analyses of previously published data, we investigated the relation between the mean initial serum zinc concentration of a study population and their mean growth responses to zinc supplementation in randomized intervention trials among children. The results from depletion/repletion studies indicate that serum zinc concentrations respond appreciably to severe dietary zinc restriction, although there is considerable interindividual variation in these responses. There is also clear evidence that both individual and population mean serum zinc concentrations increase consistently during zinc supplementation, regardless of the initial level of serum zinc concentration. By contrast, an individual's serum zinc concentration does not reliably predict that person's response to zinc supplementation. Serum zinc concentration can be considered a useful biomarker of a population's risk of zinc deficiency and response to zinc interventions, although it may not be a reliable indicator of individual zinc status.

Teacher Identification of Elementary School Children with Hearing Loss

1978 ◽  
Vol 9 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Richard H. Nodar
Keyword(s):  
Elementary School ◽  
Hearing Loss ◽  
School Children ◽  
Elementary School Children ◽  
Total Sample ◽  
Hearing Impaired ◽  
Teacher Interviews ◽  
Teacher Screening ◽  
Children With Hearing Loss ◽  
Hearing Problems

The teachers of 2231 elementary school children were asked to identify those with known or suspected hearing problems. Following screening, the data were compared. Teachers identified 5% of the children as hearing-impaired, while screening identified only 3%. There was agreement between the two procedures on 1%. Subsequent to the teacher interviews, rescreening and tympanometry were conducted. These procedures indicated that teacher screening and tympanometry were in agreement on 2% of the total sample or 50% of the hearing-loss group. It was concluded that teachers could supplement audiometry, particularly when otoscopy and typanometry are not available.

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