Gender and age aspects of lung cancer incidence in a region with a developed petrochemical industry

2020 ◽  
Vol 30 (4) ◽  
pp. 408-412
Author(s):  
G. G. Maksimov ◽  
Yu. G. Aznabaeva ◽  
E. V. Kirillova ◽  
V. M. Akhmetov
Keyword(s):  
Lung Cancer ◽  
Petrochemical Industry ◽  
Age Groups ◽  
Age Dependence ◽  
Upward Trend ◽  
Gender And Age ◽  
Reduction Of Emissions ◽  
First Time ◽  
Over 40 Years ◽  
Observation Period

The aim of the study is to study the gender-age aspects of the incidence according to the materials of the Republican Oncologic Dispensary.Methods. For the observation period from 2010 to 2017 the incidence of lung cancer in men is more common – in some cities from 2 to 7 times in different age groups.Results. For the first time, lung cancer in men and women is mainly recorded in the age group of 30 – 39 years. In other age groups, no clear gender-age dependence has been identified, in addition to the upward trend in morbidity rates in persons over 40 years.Conclusion. It was found that the reduction of emissions of different groups of carcinogens in the air in Ufa and Sterlitamak led to a decrease in the incidence of respectively 9.72 and 31.17%, and an increase in emissions in Salavat and Oktyabrsky increased by 6.53 and 18.33%.

scholarly journals HELMINTHOSES OF THE SHEEP OF BREED EDILBAYEVSKAYA IN THE CONDITIONS OF ALTAI REGION

2019 ◽  
pp. 216-220
Author(s):  
Efremova ◽  
Udaltsov
Keyword(s):  
Gastrointestinal Tract ◽  
Age Groups ◽  
Scientific Data ◽  
Fecal Samples ◽  
Low Level ◽  
Altai Region ◽  
Gender And Age ◽  
The Family ◽  
First Time

New scientific data on the modern epizootic situation on helminthoses of sheep of the breed Edilbayevskaya introduced on the territory of Altai region are provided. To study the contamination of animals with helminths, ovoliroscopic methods commonly used in parasitology were applied. In total 889 fecal samples received from sheep of different gender and age groups are investigated. Gelminthocomplex of animals is characterized by a variety. Tapeworms include parasites of the suborder Anoplocephalata, the family Anoplocephalidae, the genus Moniezia (M. brodeni, M. expanza) and the family Avitellinidae of the genus Thysaniezia (Thysaniezia giardi). Roundworms belong to the Strongylata suborder and are represented by 4 genera nematodes – Nematodirus, Ostertagia, Hemonchus, Oesophagostomum. The infection of lambs with helminths, including Nematodirus spp. and Moniezia spp. in 1.6–3.8 times more than at adult animals also makes respectively 48.1; 42.9 and 15.8%. A distinction of the sheep hermitage of the breed Edilbaevskaya is the low level of infection of animals with strangulates of the gastrointestinal tract, including esophagostomies (0.19%), ostertagies (1.3%), and hemones (0.2%). The dominating and subdominating components of helminthocomplex are Nematodirus spp. and Moniezia spp. For the first time the Skrjabinema ovis is registered in territory of Altai region.

scholarly journals Lung cancer in Kazakhstan: age-gender features

2020 ◽  
Vol 55 (1) ◽  
pp. 3-8
Author(s):  
D. R. KAIDAROVA ◽  
O. V. SHATKOVSKAYA ◽  
Zh. Zh. ZHOLDYBAY ◽  
A. Zh. ZHYLKAIDAROVA ◽  
A. S. PANINA
Keyword(s):  
Lung Cancer ◽  
Age Groups ◽  
Risk Groups ◽  
Pilot Projects ◽  
Men And Women ◽  
Screening Programs ◽  
Incidence And Mortality ◽  
Gender And Age ◽  
Gender Characteristics ◽  
Gender Features

Relevance: Over the years, lung cancer (LC) remains the leading cause of cancer deaths in Kazakhstan. In 2018, LC was diagnosed in 3741 people in the RK, and 2377 dies from LC. The purpose of this study was to assess the age-gender characteristics of morbidity and mortality from LC in Kazakhstan based on statistical and literature data. Results: The conducted analysis by gender and age showed a consistent and significant increase in LC mortality in the RK, starting from the age of 40-44 years. The highest incidence and mortality were registered in the age groups of 65-69 years and 70+ years. In general, in all age categories, the incidence and mortality in men exceeded the incidence and mortality in women by 4.5–5.3 times. The highest mortality in men and women of all ages was registered in 2009 (34.3‰ and 6.9‰, respectively), the lowest – in 2019 (20.8‰ in men and 4.6‰ in women). Conclusions: The results of the assessment can be used to improve early diagnosis of LC and in the preparation of national screening programs and regional pilot projects for LC prevention and the identification of risk groups. The use of the results will contribute to increasing the effectiveness of treatment, improving the five-year survival of patients, reducing the level of neglect and mortality from LC.

The Werther effect after television films: new evidence for an old hypothesis

1988 ◽  
Vol 18 (3) ◽  
pp. 665-676 ◽  
Author(s):  
A. Schmidtke ◽  
H. Häfner
Keyword(s):  
Age Groups ◽  
Male Student ◽  
First Episode ◽  
Werther Effect ◽  
Quasi Experimental ◽  
Railway Suicide ◽  
First Time ◽  
New Evidence ◽  
Over 40 Years ◽  
Age And Sex

SynopsisIn this study it was possible to prove the Werther effect in suicides after watching fictional models for the first time. A twice-broadcast (1981, 1982) six-episode weekly serial showing the railway suicide of a 19-year-old male student provided a quasi-experimental ABABA design to investigate differential effects of suicide imitation. Imitation effects were most clearly observable in the groups whose age and sex were closest to those of the model. Over extended periods (up to 70 days after the first episode), the number of railway suicides increased most sharply among 15- to 19-year-old males (up to 175%); the effect steadily decreased in the older age groups, so that no effect was observable for males over 40 years and females over 30 years. Also, the imitation effects remained detectable for longer periods in the groups closest in age to the model. The increases observed after the first and second broadcast for males aged > 30 years closely corresponded with the respective audience figures for the two showings.

scholarly journals Measurement Invariance of the Chinese Job Performance Questionnaire (CJPQ) across Gender and Age among Doctors

2020 ◽  
Author(s):  
Yanjie Yang
Keyword(s):  
Job Performance ◽  
Measurement Equivalence ◽  
Age Groups ◽  
Chinese Version ◽  
Gender And Age ◽  
Group Methods ◽  
Measurement Consistency ◽  
Fit Index ◽  
Chinese Physicians ◽  
First Time

Abstract Background At present, China urgently needs an effective and reliable tool to measure the job performance of doctors. For the first time, this study examined the measurement equivalence of the Chinese version of the Job Performance Questionnaire (CJPQ) in different genders and age groups among Chinese physician group. Methods The subjects of this study were 1901 doctors from 7 ‘grade-three’ hospitals in Harbin, Heilongjiang Province, China, with an average age of 36.59±7.91 years. And this study adopted the Chinese version of the Job Performance Questionnaire (CJPQ) compiled by Chinese scholar Qiang Lin, which includs 3 dimensions, 33 items in total and adopts the five-point Likert scoring system. Demographic variables were analyzed by SPSS 21.0 and measurement consistency tests were performed using AMOS 17.0. Results The results showed that for different genders, all changes in the CFI (Comparative Fit Index) were <0.01, indicating that the Chinese version of the Job Performance Questionnaire (CJPQ) is equivalent in terms of gender. Similarly, for subjects of different ages, all changes in CFI were also <0.01, indicating that the CJPQ is also equivalent in regard to age. Conclusions The measurement equivalence of the Chinese version of the Job Performance Questionnaire (CJPQ) among Chinese physicians of different genders and age groups is fully established.

Measurement Invariance of Divergent Thinking Across Gender, Age, and School Forms

2009 ◽  
Vol 25 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Jörg-Tobias Kuhn ◽  
Heinz Holling
Keyword(s):  
Measurement Invariance ◽  
Divergent Thinking ◽  
Factor Model ◽  
Age Groups ◽  
Thinking Skills ◽  
Specific Model ◽  
Confirmatory Factor Analyses ◽  
Domain Specific ◽  
Gender And Age ◽  
Confirmatory Factor

The present study explores the factorial structure and the degree of measurement invariance of 12 divergent thinking tests. In a large sample of German students (N = 1328), a three-factor model representing verbal, figural, and numerical divergent thinking was supported. Multigroup confirmatory factor analyses revealed that partial strong measurement invariance was tenable across gender and age groups as well as school forms. Latent mean comparisons resulted in significantly higher divergent thinking skills for females and students in schools with higher mean IQ. Older students exhibited higher latent means on the verbal and figural factor, but not on the numerical factor. These results suggest that a domain-specific model of divergent thinking may be assumed, although further research is needed to elucidate the sources that negatively affect measurement invariance.

Zeolites Fit For A Crown: Probing Host-Guest Interactions with Thermogravimetric Methods

2018 ◽  
Author(s):  
Asel Sartbaeva ◽  
Paul R. Raithby ◽  
Remi Castaing ◽  
Antony Nearchou
Keyword(s):  
Mass Spectrometry ◽  
Thermal Analysis ◽  
Differential Thermal Analysis ◽  
Petrochemical Industry ◽  
Rational Use ◽  
New Methodologies ◽  
First Time ◽  
Kinetics Of

Through a combination of thermogravimetry, mass spectrometry and differential thermal analysis, we demonstrate for the first time that all four zeolites show experimental differences in their host-guest interactions with 18C6. In addition, we have estimated the kinetics of 18C6 decomposition, which is a technique that has not been applied to zeolites previously. Using these findings as a toolkit, a more rational use of OSDAs can be utilised to prepare designer zeolites. Furthermore, the new methodologies presented herein can be applied to current zeolites, such as MFI-type zeolites used in the petrochemical industry.

Green synthesis of nanomaterials for early lung cancer detection

2018 ◽  
pp. 1-1
Keyword(s):  
Lung Cancer ◽  
Green Synthesis ◽  
Cancer Detection ◽  
World Wide ◽  
Early Stage ◽  
Age Groups ◽  
Early Lung Cancer ◽  
Lung Cancer Detection ◽  
Synthesis Of Nanomaterials

Lung cancer is the foremost cause of cancer-related deaths world-wide [1]. It affects 100,000 Americans of the smoking population every year of all age groups, particularly those above 50 years of the smoking population [2]. In India, 51,000 lung cancer deaths were reported in 2012, which include 41,000 men and 10,000 women [3]. It is the leading cause of cancer deaths in men; however, in women, it ranked ninth among all cancerous deaths [4]. It is possible to detect the lung cancer at a very early stage, providing a much higher chance of survival for the patients.

Fortuna

2018 ◽  
Author(s):  
Daniele Miano
Keyword(s):  
Middle Ages ◽  
Historical Development ◽  
Conceptual Analysis ◽  
Dominant Role ◽  
Age Groups ◽  
New Approach ◽  
Good Fortune ◽  
Gender And Age ◽  
New Meanings ◽  
And Gender

This book focuses on the Latin goddess Fortuna, one of the better known deities in ancient Italy. The earliest forms of her worship can be traced back to archaic Latium, and she was still a widely recognized allegorical figure during the Middle Ages and the Renaissance. The main reason for her longevity is that she was a conceptual deity, and had strong associations with chance and good fortune. When they were interacting with the goddess, communities, individuals, and gender and age groups were inevitably also interacting with the concept. These relations were not neutral: they allowed people to renegotiate the concept, enriching it with new meanings and challenging established ones. The geographical and chronological scope of this book is Italy from the archaic age to the late Republic. In this period Italy was a fragmented, multicultural and multilinguistic environment, characterized by a wide circulation of people, customs, and ideas, in which Rome played an increasingly dominant role. All available sources on Fortuna have been used: literary, epigraphic, and archaeological. The study of the goddess based on conceptual analysis will serve to construct a radically new picture of the historical development of this deity in the context of the cultural interactions taking place in ancient Italy. The book also aims at experimenting with a new approach to polytheism, based on the connection between gods and goddesses and concepts.

scholarly journals Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jianyu Wang ◽  
Doudou Liu ◽  
Zhiwei Sun ◽  
Ting Ye ◽  
Jingyuan Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Stem Cells ◽  
Cancer Stem Cells ◽  
Cell Lines ◽  
Human Cancer ◽  
Suppressor Activity ◽  
Self Renewal ◽  
Tumor Suppressor Activity ◽  
Lung Cancer Stem Cells ◽  
First Time

AbstractIt has been postulated that cancer stem cells (CSCs) are involved in all aspects of human cancer, although the mechanisms governing the regulation of CSC self-renewal in the cancer state remain poorly defined. In the literature, both the pro- and anti-oncogenic activities of autophagy have been demonstrated and are context-dependent. Mounting evidence has shown augmentation of CSC stemness by autophagy, yet mechanistic characterization and understanding are lacking. In the present study, by generating stable human lung CSC cell lines with the wild-type TP53 (A549), as well as cell lines in which TP53 was deleted (H1229), we show, for the first time, that autophagy augments the stemness of lung CSCs by degrading ubiquitinated p53. Furthermore, Zeb1 is required for TP53 regulation of CSC self-renewal. Moreover, TCGA data mining and analysis show that Atg5 and Zeb1 are poor prognostic markers of lung cancer. In summary, this study has elucidated a new CSC-based mechanism underlying the oncogenic activity of autophagy and the tumor suppressor activity of p53 in cancer, i.e., CSCs can exploit the autophagy-p53-Zeb1 axis for self-renewal, oncogenesis, and progression.

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