scholarly journals Ocular manifestations and clinical profile of multisystemic inflammatory syndrome in children during COVID-19 pandemic

2021 ◽  
Vol 10 (1) ◽  
pp. 173
Author(s):  
Arnab Mandal ◽  
Ekta Kumari ◽  
Amaresh Roy ◽  
Mousumi Bandyopadhyay
Keyword(s):  
West Bengal ◽  
Clinical Manifestations ◽  
Cervical Lymphadenopathy ◽  
Chest Discomfort ◽  
Cross Sectional ◽  
Childhood Disease ◽  
Medical College ◽  
Ocular Manifestations ◽  
Eyelid Swelling ◽  
Inflammatory Syndrome

Background: Multisystemic inflammatory syndrome in children (MIS-C) is a new childhood disease, which is associated with Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). To evaluate ocular manifestations and clinical characteristics of MIS-C during COVID-19 pandemic.Methods: A cross-sectional observational study was conducted among 48 MIS-C patients (≤19 years) at Burdwan Medical college and hospital in West Bengal, India from April 2021 to June 2021. History taking, clinical examination and necessary investigations of all the patients were done.Results: Out of 48 patients, 18 patients (37.5%) presented with conjunctivitis, 4 (8.3%) with eyelid swelling, 2 (4.2%) with episcleritis, 2 (4.2%) with papilledema, 1 (2.1%) with subconjunctival haemorrhage, 1 (2.1%) with uveitis, 1 (2.1%) with retinitis and 4 (8.3%) with decreased vision. Other clinical manifestations included fever, skin rash, loose stool, vomiting, abdominal pain, cough, peripheral oedema, myalgia, breathlessness, altered sensorium, cervical lymphadenopathy, shock, oliguria, chest discomfort and joint swelling. Serum inflammatory, coagulation and cardiac markers were deranged.Conclusions: Ocular and other clinical manifestations in MIS-C were due to post-COVID immuno-dysregulation resulting in “cytokine storm” and hyper-inflammatory response. Conjunctivitis was the most common ocular manifestation. There was a positive correlation between severity of the conjunctival hyperaemia and level of serum inflammatory markers.

A STUDY ON EXPRESSION PROFILE OF BASAL MARKER CD44 AND LUMINAL MARKER CK20 IN UROTHELIAL NEOPLASM AND ITS CORRELATION WITH WHO GRADING AND STAGING OF TUMOUR

2021 ◽  
pp. 29-32
Author(s):  
Krishnendubikas Bag ◽  
Anish kumar Rakshit ◽  
Gopinath Barui
Keyword(s):  
Urothelial Carcinoma ◽  
West Bengal ◽  
Strong Association ◽  
Lower Grade ◽  
Tumour Grade ◽  
Cross Sectional ◽  
Over Expression ◽  
Medical College ◽  
Basal Marker ◽  
Luminal Marker

Aim: Histomorphological study of urothelial carcinoma on TRBT and Cystectomy specimen and its categorization on the basis of WHO grading & pTNM staging and to nd out the correlation between CK20 and CD44 exprression with tumour grade, pTNM staging. Material And Method: This descriptive cross sectional prospective study was conducted in the Department of Pathology, R G Kar Medical College & Hospital Kolkata in collaboration with Department of Urosurgery, R G Kar Medical College & Hospital, Kolkata, West Bengal. The present study is intended to nd out over expression of CD44 & CK20 in Urothelial Carcinoma of Bladder and correlate with tumour grade and clinical features. Result: There is strong association between CD44, CK20 expression and Stage of Urothelial Carcinoma cases and had a strong association between CD44 expressions and grade Urothelial Carcinoma cases. Conclusion: CK20 overexpression was seen more signicantly in High Grade tumours HGPUC (p < 0.05) as well as advanced stage pT2 and CD44 overexpression was more signicantly in lower grade tumours LGPUC (p<0.05) as well as lower stages pT1 in urothelial carcinoma. An inverse relasionship was noted in the staining patterns of CK20 and CD44 within individual cases as well as aggregate data,with (68.24%) of tumours with CD44 loss showing CK20 positivity.

SOCIODEMOGRAPHIC AND ANTHROPOMETRIC PROFILE OF DIABETIC PATIENTS ATTENDING IN A DIABETIC CLINIC IN A TERTIARY MEDICAL COLLEGE AND HOSPITAL, WEST BENGAL

2021 ◽  
pp. 12-15
Author(s):  
Smarajit Banik ◽  
Sandip Saha ◽  
Sudipan Mitra ◽  
Ujjwal Pattanayak ◽  
Rajib Sikder ◽  
...  
Keyword(s):  
West Bengal ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Diabetes Clinic ◽  
Cross Sectional ◽  
Medical College ◽  
Study Participants

Background: Diabetes mellitus is one of the important causes of morbidity and mortality. With a rise in non communicable diseases in India, diabetes has become a modern epidemic showing a rising trend in West Bengal also. A large number of diabetes patients come to the diabetes clinic of our tertiary care hospital in North Bengal Medical College and Hospital, Darjeeling, West Bengal. The large proportion of patients presenting with this condition prompted us to study the Sociodemographic and Anthropometric Prole of such patients. Methods: This was a descriptive hospital based cross sectional study involving a total of 344 diabetic patients enrolled in the diabetes clinic of a tertiary care teaching hospital from December 2019 to February 2020. A self-administered questionnaire was used to collect data and was analyzed in Microsoft excel sheet and using SPSS 20.0 software. Results: Among the 344 study participants, we found that 220 (63.95%) were males and 124 (36.05%) were females. Diabetes was more common among those aged 51-60 years 108 (31.40%). Family history was present among 188 (54.65%) of the diabetic patients. Almost 160 (46.51%) patients have diabetes 1.1 – 5 years. Hypertension was present among 216 (62.79%) patients. Almost 218 (63.37%) of the patients were overweight and 84 (24.42%) were obese. Conclusions: The diabetic patients presenting to this tertiary care hospital belong lower socioeconomic strata and having limited education in their age group. There is high proportion of obesity and hypertension among them.

scholarly journals Perception and Willingness towards Eye Donation in an urban community of West Bengal

2020 ◽  
Vol 12 (2) ◽  
pp. 290-297
Author(s):  
Shibaji Gupta ◽  
Seshadri Kole ◽  
Saikat Bhattacharya ◽  
Debjani Guchhait
Keyword(s):  
Higher Education ◽  
Mass Communication ◽  
West Bengal ◽  
Urban Community ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Economic Class ◽  
Medical College ◽  
Corneal Blindness ◽  
Eye Donation

Introduction: Corneal blindness, though treatable, contributes largely to the burden of blindness. With 1.2 million existing cases of corneal blindness in India, the demand for cornea collection is increasing. 69349 corneas were collected in 2018-19 but it is much less than what is needed. Faulty perceptions and unwillingness are two major hurdles against a scenario favourable towards eye donation. The objectives of the study was to assess the perception and willingness towards eye donation and the socio-demographic variables that affect such perception and willingness, in an urban community of West Bengal. Materials and methods: In this cross-sectional study conducted among adult residents of the urban field practice area of Medical College Kolkata, data was collected from randomly selected eligible members, one each from all the available families by interviewing them using a validated pre tested schedule. Results: Eighty nine (52.3%) among 170 interviewed participants had Secondary level education or higher, 49.4% had outdoor engagement. 128 participants reported ocular morbidity in the family but only 126 had heard about eye donation. 98 (77.8%) of these 126, had favourable perception towards eye donation. Among these 98 participants, 40 were willing to pledge for eye donation. Higher education and outdoor engagement significantly predicted favourable perception, while willingness significantly increased with participants belonging to higher socio-economic class and with higher education. Conclusions: Compared to favourable perception, willingness of pledging eyes was lesser due to various false notions. Proper education through usage of means of mass communication and stress upon school education is needed to address these hurdles.

scholarly journals Assessment of non-ketotic hypoglycaemia in new born attending in Malda Medical College and Hospital

2017 ◽  
Vol 4 (5) ◽  
pp. 1803
Author(s):  
Indranil Dawn ◽  
Sk. Jeauddin ◽  
Gauranga Biswas ◽  
Jadab Kumar Jana
Keyword(s):  
Blood Glucose ◽  
Ketone Bodies ◽  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Acid Oxidation ◽  
Galactose Metabolism ◽  
Cross Sectional ◽  
New Born ◽  
Medical College ◽  
Ketotic Hypoglycemia

Background: Blood glucose level of <40/dl irrespective of period of gestation is known as hypoglycaemia. Nonketotic hypoglycaemia is associated with disorders of fructose or galactose metabolism, hyperinsulinism, fatty acid oxidation and GH deficiency. Aim of our study to detect the new born having clinical manifestations of hypoglycaemia, measure the capillary blood glucose and urinary ketone bodies in neonates with sign and symptoms of hypoglycaemia and to perform detail work up of neonates having non ketotic hypoglycaemia.Methods: It is hospital based cross-sectional study carried out for one calendar year extending from 01.01.2015 to 31.12.2015.Results: Thirty-five patients were identified as hypoglycemic Nine patients were diagnosed with non ketotic hypoglycemia for a prevalence of 8.5/100, 00. Two patients had the low growth hormone (GH) levels (0.4 ng/ml and 0.5 ng/ml). Three patients had increased Asparate Aminotransferase (AST) and Alanine Aminotransferase (ALT) level. Three patients increased urinary acetyl-carnitine level.Conclusions: Patient suffering from different congenital disorder and an extensive and overzealous workup for endocrinopathy or inborn error of metabolism is necessary.

scholarly journals A cross sectional study on adequacy of blood transfusion and transfusion related infections in thalassemic patients attending a medical college hospital, West Bengal

2018 ◽  
Vol 5 (8) ◽  
pp. 3596
Author(s):  
Tarun Kumar Sarkar ◽  
Pulak Kumar Jana ◽  
Jasmine M. ◽  
Timiresh Kumar Das ◽  
Mrinmoy Adhikary ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
West Bengal ◽  
Ferritin Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Blood Samples ◽  
Medical College ◽  
Study Participants

Background: Thalassemia is more prevalent in India. The main treatment of Thalassemia is blood transfusion. But the transfusion of blood has many side effects like iron overload, transfusion related infections etc. The objectives of the study were to assess the adequacy of blood transfusion for thalassemic patients and to determine the magnitude of transfusion transmitted infections among those patients.Methods: A cross sectional study was conducted in Murshidabad Medical College and Hospital, West Bengal for 1 month with the sample size of 116. The blood samples from the patients were taken from the patients attending for blood transfusion in transfusion centre of Murshidabad Medical College and Hospital for two weeks dated from 24.04.2017 to 05.05.2017 to check for the hemoglobin, ferritin level and hepatitis B, C and HIV infection.Results: Among the 116 patients, even after transfusion, 94% of the study participants have their hemoglobin levels below 7 gm/dl. Only 2 individuals got their hemoglobin levels more than 9 gm/dl and only 1 patient got HIV infection post transfusion which accounts for 0.9% of study population.Conclusions: Frequent Hb estimation will help to maintain the adequacy of blood transfusion and proper screening of the blood before transfusion can help in reducing these transfusion transmitted infections.

scholarly journals Wilson's disease: A rare autosomal recessive disorder of copper metabolism

2014 ◽  
Vol 4 (2) ◽  
pp. 51-53
Author(s):  
RR Pradhan ◽  
J Gupta
Keyword(s):  
Autosomal Recessive ◽  
Wilson’S Disease ◽  
Clinical Manifestations ◽  
Copper Toxicity ◽  
Copper Metabolism ◽  
Autosomal Recessive Disorder ◽  
Wilson's Disease ◽  
Medical College ◽  
Ocular Manifestations ◽  
Membrane Bound

Wilson’s disease is an autosomal recessive disorder caused by mutations in the ATP7B gene, a membrane-bound copper-transporting ATPase. Clinical manifestations are caused by copper toxicity and primarily involve the liver, the brain and the eye. Because effective treatment is available, it is important to make this diagnosis early. We report a patient who developed features of neurological and ocular manifestations: incoordination and tremor and blurring of vision with presence of Kayser-Fleischer ring circling the cornea but no signs of hepatic dysfunction. DOI: http://dx.doi.org/10.3126/jcmc.v4i2.10866 Journal of Chitwan Medical College 2014; 4(2): 51-54

scholarly journals A cross sectional study to evaluate the clinical presentation in multisystem inflammatory syndrome in children

2021 ◽  
Author(s):  
Ambika Sood ◽  
Pancham Kumar ◽  
Rakesh Sharma ◽  
Deepak Sharma ◽  
Sanya Sharma
Keyword(s):  
Clinical Presentation ◽  
Cross Sectional Study ◽  
Study Data ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Multiple Organs ◽  
Gandhi Medical College ◽  
Inflammatory Syndrome

Background: MIS-C as a disease has varied symptoms and signs that affect multiple organs and systems in the body. The present study aimed to describe the clinical presentation among children admitted as a case of multisystem inflammatory syndrome in children in Indira Gandhi Medical College, Shimla.Methods: We conducted a cross sectional study of children with MIS-C from January to July 2021, in the pediatric ward of Indira Gandhi Medical College Shimla in Himachal Pradesh. All children admitted with a diagnosis of MISC were included in the study. Data regarding clinical presentation was extracted and analyzed using Epi Info V7 software.Results: In the present study, a total of 31 children diagnosed and admitted as a case of multisystem inflammatory syndrome in children (MIS-C) were included. Mean age of these children was 7.12±4.78 years. Among the total 16 (51.6%) were males while 15 (48.4%) were females. All 31 patients had presented with fever and 13 (41.9%) patients had fever with rash. 5 (16.1%) had cough, 1 (3.2%) child presented with hematemesis, 18 (58.1%) had tachypnea at presentation and 15 (48.4%) patients had respiratory distress. 16 (51.6%) children had complaints of vomiting, 1 (3.2%) presented with bleeding diathesis and 12 (38.7%) had hematuria, 5 (16.1%) had seizures and 8 (25.8%) presented with encephalopathy. 19 (61.3%) children had hypotension, 15 (48.4%) had hepatomegaly and 15 (48.4%) had splenomegaly.Conclusions: It is very essential to characterize this syndrome to fully understand its spectrum, therefore we need to be continuously watchful for its varied clinical presentations, both for ensuring an early diagnosis and treatment of patients suffering from MIS-C.

scholarly journals Malaria: change in a variety of clinical manifestations in Eastern India

2014 ◽  
Vol 13 (2) ◽  
pp. 150-154
Author(s):  
Pradeep Chakrabarty ◽  
Joydeep Mukherjee
Keyword(s):  
Observational Study ◽  
Clinical Features ◽  
Medical Science ◽  
Clinical Manifestations ◽  
Tertiary Hospital ◽  
Eastern India ◽  
Cross Sectional ◽  
Clinical Pattern ◽  
Medical College ◽  
Clinical Presentations

Objective: We had undertaken this study to find out the change in variety of clinical presentations in which a patient suffering from malaria could present. Materials and methods: In a retrospective, cross-sectional and observational study first 100 admitted malaria patients were taken in a tertiary hospital cum medical college at Kolkata, India from August 2009 to July 2011. Their clinical profile were noted and analysed. Results: A variety of clinical pattern was noted in various combinations, starting from fever, chill, and rigor to even hematemesis and rash. Change was noted in pattern of fever and other manifestations. Conclusion: Each patient suffering from malaria could present with a variety of clinical features with some specific patterns in specific cases as discussed. Treatment of malaria in Eastern India was efficacious but costly. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18298 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.150-154

scholarly journals Estimation of Perceived Stress among Doctors in a Peripheral Tertiary Government Medical College of West Bengal: A Cross-sectional Study

2021 ◽  
Author(s):  
Ranjan Das ◽  
Nazrul Mallick ◽  
Ashis Debnath ◽  
Bijit Biswas ◽  
Sumit Mukherjee
Keyword(s):  
Logistic Regression ◽  
Perceived Stress ◽  
West Bengal ◽  
Tertiary Care ◽  
Moderate Level ◽  
Government Medical College ◽  
Cross Sectional ◽  
Medical College ◽  
Family Problem ◽  
The Impact

Introduction: Doctors working in a tertiary care teaching hospital suffers higher symptoms of psychological distress. The impact of excessive stress may affect the individual employee and the organisation in terms of productivity and performance. Aim: To estimate the perceived stress among doctors and to find out the sources of their stress in a peripheral Government Medical College of West Bengal. Materials and Methods: This was an observational study, cross-sectional in design, conducted to assess the perceived stress and specific stressors among 95 doctors who were posted in a peripheral Government Medical College from June to November 2019. A Perceived Stress Scale (PSS 10) questionnaire was used to assess the perceived stress. Psycho-social and Environmental stressors were assessed using 11 items questionnaire. Data were analysed using the IBM statistical package for social sciences, (SPSS) software program (version 20.0) (Chicago, USA). Results: The majority of the participant (80%) had moderate level of stress, while 10.5% had low stress and 9.5% had severe stress. The mean PSS score in this study was 20.49±5.61. In univariate logistic regression analysis, significant association was found with loneliness {Odds Ratios (OR) 9.3; 95% Confidence Interval (CI)= 2.9-29.9}, family problem (OR 2.7; 95% CI=1.1-6.6) and quality of food (OR 2.9: 95% CI=1.2-7.0). Finally, loneliness (AOR 9.6; 95% CI=2.7-34.1) and family problem (AOR 3.7; 95% CI=1.3-10.1) came out to be statistically significant predictors of stress in multivariable logistic regression. Conclusion: Majority of doctors had moderate level of stress and they felt upset, nervous and stressed in last one month of preceding the survey. Professional counseling for the doctors to improve their coping and resilience behaviours is highly recommended.

scholarly journals An assessment of the learning styles of first year medical and dental students of North Bengal Medical College, Darjeeling, West Bengal, India

2020 ◽  
Vol 8 (4) ◽  
pp. 1414
Author(s):  
Sumana Panja ◽  
Pratibha Rao Lahiri ◽  
Aditi Lahiri
Keyword(s):  
Learning Styles ◽  
Learning Strategies ◽  
Learning Style ◽  
West Bengal ◽  
Sensory Modality ◽  
Dental Students ◽  
First Year ◽  
Cross Sectional ◽  
Medical College ◽  
North Bengal

Background: Learning is the act of acquiring, modifying and reinforcing existing knowledge, behavior, skills and values. This phenomenon of learning is dominated by an individual’s learning style. Learning style is a popular concept in psychology and education, and it refers to how a person learns best. This study aims to identify the Learning Styles of the first year MBBS and BDS students at NBMC by administering the questionnaire of the VARK model.Methods: This cross-sectional study was performed in the Department of Physiology at North Bengal Medical College, West Bengal after. The VARK questionnaire 7.8 version was administered to 180 first year MBBS and BDS students from the 2017-2018 batch who had volunteered for the study. The Questionnaire consisted of 16 questions, along with a scoring chart. Students were allowed to choose more than one option. If in majority of the questions they opted for a single sensory modality they were considered as unimodal learners and if they chose multiple options, they were recognized as multimodal learners.Results: The study showed 57% of the students to be multimodal learners and 43% to be unimodal learners. Read/Write was the most preferred (31.22%) sensory modality followed by kinesthetic mode (29.57%).Conclusions: As majority of our students are multimodal learners teachers should incorporate active teaching and learning strategies to cater to all types of learners. Also, as the most preferred method is Read/Write which includes googling and the use of internet to browse for information, we must try and incorporate e-learning into our curriculum.

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