scholarly journals Vitamin D status in children with cerebral palsy

2017 ◽  
Vol 4 (2) ◽  
pp. 615
Author(s):  
Sowjan Manohar ◽  
Rajakumar Ponnandai Gangadaran
Keyword(s):  
Vitamin D ◽  
Cerebral Palsy ◽  
Vitamin D Deficiency ◽  
Tamil Nadu ◽  
Total Serum ◽  
Case Group ◽  
Vitamin D Status ◽  
Feeding Difficulties ◽  
Vitamin D Levels ◽  
Children With Cerebral Palsy

Background: The aim of the study was to find the prevalence of vitamin D status - vitamin D deficiency and insufficiency in children with cerebral palsy and to compare them with normal children. To identify the risk factors associated with vitamin D deficiency in these children.Methods: A prospective case control study was done in 200 children in Shri Sathya Sai Medical College and Research Institute, Ammapettai, Thiruporur, Tamil Nadu, India over a period of one year from December 2014 to December 2015 after obtaining approval from institutional ethical committee. Study group contained 100 children with cerebral palsy. 100 Age and sex matched children were taken as controls. Children included in the study were between 1 to 12 years. All children were subjected to the following investigations: serum calcium-total, serum phosphorus, serum alkaline phosphatase (SAP) levels. These were determined by an automated analyzer. The 25OH vitamin D levels were estimated by CLIA (chemi luminescence immunoassay) method. Results: Vitamin D deficiency was observed in 32 (32%) and insufficiency in 61 (61%) of children with cerebral palsy in case group. Similarly, vitamin D status studied in control children was found that majority of them 49 (49%) was normal. While 38 (38%) were vitamin D insufficient, 13 (13%) showed deficient levels (p <0.0000001).Conclusions: The presence of feeding difficulties, poor sunlight exposure, poor nutritional status, and the use of antiepileptic drugs, type of CP and the functional grade of CP had statistically significant association with Vitamin D deficiency in these children.  

scholarly journals Vitamin D Levels in Children and Adolescents with Cerebral Palsy: Cross-sectional Study / Níveis de Vitamina D em Crianças e Adolescentes com Paralisia Cerebral: Estudo Transversal

2021 ◽  
Vol 4 (3) ◽  
pp. 11938-11949
Author(s):  
Marcela Almeida Linden ◽  
Elizete Aparecida Lomazi ◽  
Gabriel Hessel ◽  
Maria Ângela Bellomo-Brandão
Keyword(s):  
Vitamin D ◽  
Cerebral Palsy ◽  
Children And Adolescents ◽  
Vitamin D Deficiency ◽  
Sun Exposure ◽  
Food Sources ◽  
Control Group ◽  
Case Group ◽  
Healthy Children ◽  
Vitamin D Levels

Aim: Tetraparetic Cerebral Palsy (TCP) patients may present risks factors for Vitamin D deficiency such as increased risk of malnutrition and possibly infrequent sun exposure. The present study aimed to compare the vitamin D status in this population of TCP pediatric patients (Case Group) and compare them with healthy children and adolescents (Control Group). Methods: The clinical data obtained were: gender, age, weight, height, nutritional status, consumption of vitamin D food sources, sun exposure and serum levels of vitamin D. Vitamin D deficiency was defined as 20 ng/mL or less of 25(OH)D; “insufficiency” was defined as between 21-29 ng/mL; “sufficiency” was defined as between 30-100 ng/mL.1 Results: Sixty patients aged 3 to 20 years old were divided into two groups: the Control Group (n=30) and the Case Group (n=30) composed of individuals with TCP. Vitamin D levels did not differ between groups; the mean levels were 26.65 ng/mL (SD: 10.51) in the Case Group and, 28.93 ng/mL (SD: 9.26) in the Control Group. Conclusion: There was no difference identified between vitamin D levels among TCP and control patients, and no relationship between risk factors and serum 25(OH)D levels was observed. Even though Brazil is a tropical country with abundant sunshine during most of the year, there is still a considerable number of individuals with vitamin D classifications of insufficiency and deficiency in our study (N= 34/60). This should be alarming for healthcare professionals who work with the pediatric population, which is a population at risk for the development of disability.

scholarly journals Vitamin D status in pregnant women and their newborns in a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 5071
Author(s):  
Harleen Kour ◽  
Shashi Gupta ◽  
Swarn K. Gupta ◽  
Bawa Ram Bhagat ◽  
Gagan Singh
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Tertiary Care ◽  
North India ◽  
Care Hospital ◽  
Vitamin D Status ◽  
Pregnant Females ◽  
Vitamin D Levels ◽  
Maternal And Newborn

Background: In the recent years there has been an increased understanding of the role that vitamin D plays in regulation of cell growth, calcium absorption and immunity and its impact on the developing fetus and maternal health is of significant concern. This study aims at evaluating the Vitamin D status in pregnant women and their newborns.Methods: A cross sectional study was done on 100 pregnant females according to inclusion and exclusion criteria. At the time of delivery, maternal blood was collected, and newborn samples were taken from newborn side of umbilical cord and sent for analysis.Results: The prevalence of Vitamin D deficiency has been found to be 85% of pregnant females and 91% of the newborns. Only 5% of pregnant females and 1% of the newborns showed Vitamin D sufficiency. Maternal and newborn vitamin D levels show a positive correlation. Mean maternal and newborn Vitamin D levels were found to be 16.78±7.04 ng/mL and 11.29±5.75 ng/ml.Conclusions: Vitamin D deficiency is highly prevalent among pregnant women in north India. Low maternal vitamin D levels lead to vitamin D deficiency in the newborns also.

scholarly journals Levels of vitamin D among overweight and obese adolescents: an observational study

2017 ◽  
Vol 4 (6) ◽  
pp. 1934
Author(s):  
T. Prashanth Reddy ◽  
Kishore Reddy ◽  
Madhu Sudhan Reddy ◽  
Manjunath G. A.
Keyword(s):  
Vitamin D ◽  
Observational Study ◽  
Vitamin D Deficiency ◽  
Overweight And Obesity ◽  
Dietary Factors ◽  
Vitamin D Status ◽  
Obese Adolescents ◽  
Vitamin D Levels ◽  
Study Results ◽  
Wide Range

Background: Normal growth and development requires vitamin D, and its deficiency compromises long term health and increases the risk of chronic disease. Severe vitamin D deficiency include rickets, osteomalacia, osteoporosis, increased risk of fracture, tooth loss. Studies indicate that vitamin D insufficiency (less severe than deficiency) is associated with a wide range of illnesses and chronic conditions, including type 1 diabetes, hypertension, multiple sclerosis and many types of cancer. Currently world is facing an unrecognized and untreated pandemic of vitamin D deficiency. This study aims at showing the relation between Vitamin D status and obesity in adolescent children and to know the dietary factors, life style factors like physical activity contributing to overweight and obesity in adolescents.Methods: Study design: This is an observational study of 30 overweight and obese adolescents based on BMI were studied and their Vitamin D levels were assessed.Results: A total of 14(46.7%) overweight and 16(53.3%) obese adolescents Vitamin D levels were assessed. 20(66.7%) had vitamin D levels <20ng/ml that is in the deficiency range.4(13.3%) had in the insufficiency range (21-30ng/ml), 6(20%) had in the sufficient range. Results shows vitamin D levels were significantly less in obese and overweight adolescents.Conclusions: Study results confirm that Vitamin D deficiency or insufficiency is common to obese and overweight adolescents, this may help to explain the relationship between obesity and several chronic diseases that are associated with poor Vitamin D status.

scholarly journals Vitamin D levels in pregnant women in Uttarakhand, India

2017 ◽  
Vol 7 (1) ◽  
pp. 169
Author(s):  
Nikita Pahuja ◽  
Nidhi Chauhan ◽  
Vinita Kalra
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Bone Growth ◽  
Innate Immune ◽  
Vitamin D Status ◽  
Medical Sciences ◽  
Healthy Pregnancy ◽  
Vitamin D Levels ◽  
Increase Risk ◽  
Sufficient Vitamin

Background: A balanced, nutritious diet is an important aspect of a healthy pregnancy and its outcome. Vitamin D plays an important role in regular bone growth and in adequate function of innate immune system, including barrier function of mucous membrane. Vitamin D deficiency in adult females may increase risk of pre-eclampsia, gestational diabetes, bacterial vaginosis. The present study was undertaken to find the prevalence of Vitamin D deficiency in the women of Uttarakhand, India.Methods: The study was conducted in the Department of Obstetrics and Gynecology, Himalayan Institute of Medical Sciences (HIMS), Swami Ram Nagar, Dehradun, India over a period of 12 months. Sample size was 100 pregnant females attending antenatal clinic.Results: Out of 100 subjects, 21 (21%) had deficient, 69 (69%) had insufficient and 10 (10%) had sufficient vitamin D status. Out of 21 deficient subjects, 18 (85.71%) were Hindus, 2 (9.52%) were Muslims, 1 (4.76%) was Sikh and no deficiency was seen in Christian. In the present study, deficient vitamin D status was seen in 1 (4.76%) in lower, 16 (76.19%) in middle and 4 (19.04%) subjects in upper socioeconomic status.Conclusions: It is concluded from our study that there is serious vitamin D deficiency and insufficiency in the women of Uttarakhand, India.

scholarly journals Vitamin D Status of Epileptic Children in India: A Prospective Cross-Sectional Study from a Tertiary Care Centre

2020 ◽  
Vol 10 (01) ◽  
pp. e87-e92
Author(s):  
Chandrika Azad ◽  
Vishal Guglani ◽  
Jasbinder Kaur ◽  
Roosy Aulakh ◽  
Sukhvinder Singh ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
Epileptic Children ◽  
25 Oh Vitamin D

AbstractVitamin D deficiency is prevalent all over the world, especially in tropical countries. In epileptics, antiepileptic drugs (AED) and associated comorbidities further impact vitamin D status. The aim of this study is to estimate the prevalence of 25(OH) vitamin D deficiency in epileptic children and evaluate probable risk factors. A cross-sectional study of 200 children between 1 and 18 years of age on AED was undertaken in the pediatric neurology clinic of a tertiary care center of Northern India. In all children, serum 25(OH) vitamin D levels, calcium, phosphorus, and alkaline phosphatase were estimated. The deficiency levels of vitamin D were categorized as: deficiency <20 ng/mL, insufficiency 20 to 30 ng/mL, and sufficiency >30 ng/mL. The potential risk factors for hypovitaminosis D, including type of epilepsy, AED regimen (specific medications, polytherapy vs. monotherapy), cerebral palsy, ambulatory status, intellectual disability, body mass index, gender, and vegetarianism were examined. Among the 200 enrolled children (60% boys), 106/200 (53%) were vitamin D deficient. There was no significant relation of vitamin D levels with gender, type of epilepsy, neurological deficit, and type of AED. An inverse relationship of higher phenytoin doses during monotherapy associated with lower vitamin D levels in monotherapy was found, thereby suggesting adverse effect of high doses of phenytoin on vitamin D levels. VDD is common among epileptic children on AED therapy. Vitamin D deficiency is common prevalent among epileptic children on AED therapy, and its detection and treatment correction should be an integral part of epilepsy management.

Bone mineral density and vitamin D status in ambulatory and non-ambulatory children with cerebral palsy

2014 ◽  
Vol 26 (1) ◽  
pp. 141-150 ◽  
Author(s):  
A.-K. Finbråten ◽  
U. Syversen ◽  
J. Skranes ◽  
G. L. Andersen ◽  
R. D. Stevenson ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Cerebral Palsy ◽  
Bone Mineral ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Children With Cerebral Palsy

scholarly journals PO-0828 Bone Mineral Density And Vitamin D Status In Children With Cerebral Palsy

2014 ◽  
Vol 99 (Suppl 2) ◽  
pp. A524.3-A525
Author(s):  
AK Finbråten ◽  
U Syversen ◽  
J Skranes ◽  
GL Andersen ◽  
R Stevenson ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Cerebral Palsy ◽  
Bone Mineral ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Children With Cerebral Palsy

scholarly journals Anxiety Symptoms Among Lebanese Health-care Students: Prevalence, Risk Factors, And Relationship With Vitamin D Status

2021 ◽  
Author(s):  
José-Noel Ibrahim ◽  
Léa Audi
Keyword(s):  
Health Care ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Rating Scale ◽  
Vitamin D Supplementation ◽  
Anxiety Symptoms ◽  
Vitamin D Status ◽  
Health Care Students ◽  
Vitamin D Levels ◽  
Social Difficulties

Introduction: Various emotions may arise in the context of extensive curriculum of paramedical education. Their association to biological aspects such as Vitamin D status is to be examined with regard to the prevalence of Vitamin D deficiency in the region. This research aims to evaluate the prevalence of anxiety symptoms and their relationship with Vitamin D status among Lebanese health-care students.Methods: A total of 157 university students aged 18-25 years old completed a questionnaire related to medical and psychiatric history, nutritional intake, lifestyle habits, and social difficulties. Anxiety symptoms were assessed by Hamilton Anxiety Rating Scale. Vitamin D serum levels were analyzed using ELISA technique.Results: Anxiety symptoms were present in 37.5% of students with 2.5% presenting severe anxiety. Anxiety symptoms were significantly associated to health problems (p = 0.0038), social difficulties (p = 0.001), and a family history of psychiatric disorders (p < 0.0001). Low Vitamin D levels were detected in 49.3% of participants; 77.5% having a Vitamin D insufficiency while the rest presenting a Vitamin D deficiency. Students with anxiety symptoms had significantly lower Vitamin D levels as compared to those having no anxiety manifestations (17.9 ng/mL ± 7.9 vs. 24.2 ng/mL ± 9.9, p = 0.0023). However, no significant correlation was registered between anxiety symptoms scores and Vitamin D levels.Conclusion: Anxiety symptoms were found to be relatively prevalent among health-care students and associated to low Vitamin D levels. Further studies are warranted to clarify the beneficial effect of Vitamin D supplementation in the prevention, management, and treatment of anxiety symptoms among health-care students.

scholarly journals VITAMIN D STATUS IN A HEALTHY TUNISIAN POPULATION

2022 ◽  
Author(s):  
Asma KRIR ◽  
Afef BAHLOUS ◽  
Mehdi MRAD ◽  
BOUKSILA Mouna ◽  
KALAI Safa ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Rural Areas ◽  
Hypovitaminosis D ◽  
Vitamin D Supplementation ◽  
Tunisian Population ◽  
Diabetic Patients ◽  
Dietary Intakes ◽  
Vitamin D Status ◽  
Vitamin D Levels

Vitamin D deficiency is one of the most common medical conditions worldwide. In Tunisia, several studies evaluated Vitamin D status, but this was concerning specific populations (pregnant women, obese or diabetic patients and children with asthma). The only study that evaluated Vitamin D status in a healthy Tunisian population was conducted by Meddeb and al. in 2002. The update of data available, based on the currently recommended limits, is necessary. This study aimed to estimate the prevalence of hypovitaminosis D in a healthy Tunisian population, and correlate the values with potential risk factors. It was conducted on 209 Tunisian healthy subjects. Data collected included clinical characteristics and dietary intakes. We measured 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), glycemia, creatinine, calcium, phosphorus, proteins and alkaline phosphatase levels. Hypovitaminosis D was retained for 25(OH)D concentrations <30ng/ml. Vitamin D deficiency was defined by 25(OH)D concentrations <10 ng/ml. The prevalence of hypovitaminosis D and vitamin D deficiency were respectively 92.3% and 47.6%. The main factors that were significantly associated with low vitamin D levels in our multivariate analysis were veiling, living in rural areas and sunscreen use. However, sex, age, socioeconomic level, phototype, solar exposure score, smoking and bone mass index, were not statistically associated with hypovitaminosis D. The study of relationship between vitamin D status and serum PTH levels showed a significative and negative correlation (p< 0.005). Given the high prevalence of vitamin D, an adapted health policy is essential. A widespread vitamin D supplementation and food fortification seems to be necessary in Tunisia.

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