scholarly journals Efficacy and safety of high dose hydroxyurea in transfusion dependent thalassemic children: a quasi experimental study

2017 ◽  
Vol 4 (4) ◽  
pp. 1514
Author(s):  
Kiran Suthar ◽  
Pramod Sharma ◽  
Manish Verma ◽  
Vishnu Kr. Goyal
Keyword(s):  
Statistical Significance ◽  
Significant Rise ◽  
P Value ◽  
High Dose ◽  
Comparison Study ◽  
Post Intervention ◽  
Before And After ◽  
Quasi Experimental ◽  
Haemoglobin Synthesis ◽  
Day Care Centre

Background: This study was conducted to find out whether high dose hydroxyurea is an effective and safe modality, in inducing haemoglobin synthesis to decrease blood transfusion requirement in transfusion dependent thalassemics.Methods: This quasi experimental un-control before and after comparison study was conducted in Thalassemia Day Care Centre, Department of Pediatrics over a period of six months after obtaining an approval from the Institute’s ethical committee. Fifty transfusions dependent thalassemic children belonging from 2 to 18 yrs were given hydroxyurea in dose of 20mg/kg after getting consent. Pre and post intervention haemoglobin and HbF levels were obtained using Hb electrophoresis by HPLC. Paired t test was applied to find out statistical significance and p value <0.05 was taken as significant.Results: Significant rise in haemoglobin pre and post intervention (p<0.001) but the rise in HbF was not significant (p=0.110). One patient had bone marrow depression which was reversible with drug withdrawal and one patient had rise in s. creatinine.Conclusions: High dose hydroxyurea is an effective and safe drug in inducing Hemoglobin synthesis in transfusion dependent thalassemics.  

scholarly journals Teaching Cardiac Arrhythmias Using Educational Videos and Simulator Software in Nurses: An Educational Interventional Study

2020 ◽  
Vol 21 (9) ◽  
Author(s):  
Hamed Tavan ◽  
Siros Norouzi ◽  
Masoumeh Shohani
Keyword(s):  
Cardiac Arrhythmias ◽  
Heart Diseases ◽  
Educational Interventions ◽  
P Value ◽  
Post Intervention ◽  
Significant Difference ◽  
Before And After ◽  
Quasi Experimental ◽  
The Mean ◽  
Educational Videos

Background: Cardiac arrhythmias are among the most prominent causes of mortality in patients with heart diseases. By timely diagnosis of arrhythmias, nurses can provide necessary therapeutic measures to these patients. Objectives: The purpose of this study was to determine the effects of teaching cardiac arrhythmias using educational videos and simulator software in nurses. Methods: In this quasi-experimental study, 22 novice nurses were selected based on the census method. Evaluations were performed before and after educational interventions for cardiac arrhythmia. The interventions included using simulator software and face-to-face education. A questionnaire with 20 questions regarding cardiac arrhythmias organized in 4 parts of sinus arrhythmias, atrial arrhythmias, ventricular arrhythmias, and blocks and junctional rhythm, and each with 5 questions was used to collect data. Each question was scored 1 point, and the final score ranged from 0 to 20. The scores were categorized into poor (< 10), moderate (11 - 15), and good (16 - 20) levels. Data were analyzed using SPSS V.20 software. Results: There was a significant difference in the mean of total score regarding the diagnosis of arrhythmias before (9.9) and after (15.68) the education (P value = 0.022). This indicated an increase of about 6 scores at post-intervention. The classification of the scores showed that 9 (40.9%) and 13 (59.1%) nurses had poor and moderate diagnostic abilities before training. However, following education, 10 nurses (50%) acquired moderate and 10 (50%) nurses obtained good scores. Conclusions: Arrhythmia scores varied before and after training, with the mean scores after training increased, and arrhythmia detection rate was increased after the intervention. It is advisable to use modern educational methods as good alternatives for reviewing educational content and concepts.

scholarly journals EVALUATION OF INTERACTIVE PHYSICAL ACTIVITY EDUCATION PROGRAM (IPAEP): A PRELIMINARY STUDY

2019 ◽  
Vol 4 (32) ◽  
pp. 247-258
Author(s):  
Ahmad Faezi Ab. Rashid ◽  
Nor Dalila Marican ◽  
Abdullah Mohamed Yusoff ◽  
Nurul Hafizah Mohd Yasin ◽  
Mohd Hafzal Abdul Halim ◽  
...  
Keyword(s):  
Physical Activity ◽  
University Students ◽  
Education Program ◽  
Knowledge Score ◽  
P Value ◽  
Activity Levels ◽  
Post Intervention ◽  
Before And After ◽  
Interactive Lectures ◽  
Quasi Experimental

The purpose of this study was to evaluate changes in physical activity knowledge among university students after exposure to Interactive Physical Activity Education Program (IPAEP). In current globalization, physical inactivity or sedentary lifestyle becomes a major underlying cause of chronic diseases worldwide. There is a growing concern of inadequate physical activity levels among young adult especially university students. The acquisition and dissemination of physical activity recommendations through physical activity program are essential in the delivery of an adequate level of physical activity knowledge among university students Materials and Methods: A quasi-experimental study design was conducted, and data were collected using a questionnaire among students (n=116) of Universiti Malaysia Kelantan, to evaluate the changes of physical activity knowledge after exposure to IPAEP intervention. All of them participated in 10 weeks of IPAEP intervention. In the IPAEP intervention, students were exposed to interactive lectures and various online activities related to types, risks, benefits, and key recommendations of physical activity. Pre- and post-intervention surveys were taking place before and after the program to evaluate the same measure, which is the physical activity knowledge. Data were analyzed using IBM SPSS version 25.0. Paired-sample t-tests were used to evaluate the differences between pre- and post-intervention of the physical activity knowledge scores. Result: The present study showed a significant increment in physical activity knowledge score (P-value <0.001) among university students after participating in IPAEP intervention. Conclusion: Since the present study emphasized physical activity education for university students, the IPAEP could contribute to better physical activity knowledge which eventually beneficial for their active lifestyle in the future.

scholarly journals Installation of pedal-operated alcohol gel dispensers with behavioral nudges and changes in hand hygiene behaviors during the COVID-19 pandemic: a hospital-based quasi-experimental study

2020 ◽  
Vol 9 (4) ◽  
Author(s):  
Wit Wichaidit ◽  
Sommanas Naknual ◽  
Nanta Kleangkert ◽  
Tippawan Liabsuetrakul
Keyword(s):  
Experimental Study ◽  
Hand Hygiene ◽  
Tertiary Hospital ◽  
Pathogen Transmission ◽  
P Value ◽  
Intervention Period ◽  
Post Intervention ◽  
Observation Area ◽  
Before And After ◽  
Quasi Experimental

We conducted a quasi-experimental study and compared hand hygiene behaviors at potential pathogen transmission events among outpatient visitors (according to structured observations a trained enumerator) before and after installation of 12 pedal-operated alcohol gel dispensers with behavioral nudges (signs attached to the dispensers) at a tertiary hospital in southern Thailand during the COVID-19 pandemic. The enumerator observed 243 events during the pre-intervention period and 223 events during the post-intervention period. Prevalence of hand hygiene was significantly different between the pre-intervention and post-intervention periods (0 vs 24 events, or 0% vs 11%, respectively; p-value <0.001). However, 21 of 24 hand hygiene events were of participants who came from outside the observation area, used the dispensers, then left. Nonetheless, the intervention might have helped to increase access to hand hygiene materials and created opportunities for hand hygiene among hospital visitors in general.

Change in perception of sclerotherapy results after exposure to pre–post intervention photographs

2017 ◽  
Vol 33 (4) ◽  
pp. 282-287 ◽  
Author(s):  
Fabricio R Santiago ◽  
Mario Piscoya ◽  
Yung-Wei Chi
Keyword(s):  
Varicose Veins ◽  
Statistical Significance ◽  
Wilcoxon Test ◽  
Clinical Severity ◽  
Post Intervention ◽  
Chi Square ◽  
Severity Scores ◽  
Venous Clinical Severity Score ◽  
Before And After ◽  
Chi Square Test

Objective To evaluate patients’ self-perception of cosmetic improvement before and after they were presented with pre- and postprocedure photographs after sclerotherapy with 75% dextrose. Methods Treatments included sclerotherapy of reticular and varicose veins using 75% dextrose. All treated limbs were photographed and classified according to Clinical, Etiology, Anatomy, and Pathology classification and Venous Clinical Severity Score pre- and posttreatment. The patients were queried before and after viewing the photos during these visits and indicated if they were very unsatisfied, dissatisfied, satisfied, or very satisfied. Nonparametric kappa correlation coefficient and a Chi square test were used to measure associations among agreement (p < 0.05 indicated statistical significance). The paired Wilcoxon test was used to compare statistical differences in mean Venous Clinical Severity Scores measured at different times (p < 0.05 indicated statistical significance). Data were analyzed using STATA software (version 12). Results Individuals were more satisfied with the results of sclerotherapy after exposure to images portraying their limbs two months after the procedure (p = 0.0028). This effect was maintained six months after sclerotherapy (p = 0.0027). Conclusion Patient exposure to pre- and postsurgical photographs is a simple intervention with the potential of improving patient satisfaction up to six months after treatment with sclerotherapy.

scholarly journals Promotion of Early and Exclusive Breastfeeding in Neonatal Care Units in Rural Rwanda: a Quasi-experimental Study

2020 ◽  
Author(s):  
Saidath Gato ◽  
Francois Biziyaremye ◽  
Catherine M. Kirk ◽  
Chiquita Palha De Sousa ◽  
Alain Mukuralinda ◽  
...  
Keyword(s):  
Experimental Study ◽  
Exclusive Breastfeeding ◽  
Child Survival ◽  
Neonatal Care ◽  
Post Intervention ◽  
Factors Associated ◽  
Before And After ◽  
Quasi Experimental ◽  
Evidenced Based ◽  
Additional Support

Abstract Background: Early initiation of breastfeeding after birth and ongoing exclusive breastfeeding for the first 6 months improves child survival, nutrition and health outcomes. However, only 42% of newborns worldwide are breastfed within the first hour of life. Small and sick newborns are at greater risk of not receiving breastmilk and often require additional support for feeding. This study compares breastfeeding practices in Rwandan neonatal care units (NCUs) before and after the implementation of a package of interventions aimed to improve breastfeeding, aligned with the Baby Friendly Hospital Initiative for small and sick newborns.Methods: A pre-post quasi experimental study was conducted at two District hospital NCUs in rural Rwanda from October 2017–December 2017 (pre-intervention) and September 2018–March 2019 (post-intervention). Only newborns admitted before their second day of life (DOL) were included. Data was extracted from patient charts for clinical and demographic characteristics, feeding throughout admission, and patient outcomes. Bivariate analyses were conducted using Fisher’s exact and Wilcoxon rank sum tests. Logistic regression was used to evaluate factors associated with exclusive breastfeeding at discharge following a backwards stepwise procedure.Results: Pre-intervention, 255 newborns were admitted in the NCUs and 793 were admitted in the post-intervention period. The percentage of infants who were exclusively breastfed on their day of birth, or day-of-life zero (DOL0) increased from 5.4% to 35.9% (p<0.001). For newborns discharged alive, the proportion exclusively breastfeeding increased from 69.6% to 87.0% (p<0.001). The mortality rate for all admitted newborns decreased from 16.1% to 10.5% (p<0.019). Factors associated with greater odds of exclusive breastfeeding at discharge included post-intervention time point (Odds Ratio (OR): 4.91, 95% Confidence Interval (CI) 1.99-12.11, p<0.001), and admission for infection (OR 2.99, 95%CI 1.13-7.93, p=0.027). Home deliveries (OR 0.15, 95%CI 0.05-0.47, p=0.001), preterm delivery (OR 0.36, 95%CI 0.15-0.87, p=0.0260 and delayed first breastmilk feed (OR=0.04 for DOL3 vs. DOL0, 95%CI 0.01, 0.35, p=0.004) reduced odds of exclusive breastfeeding at discharge. Conclusion: Expansion and adoption of evidenced-based guidelines, using innovative approaches, aimed at the unique needs of small and sick newborns should be expanded and adapted in similar settings to improve outcomes for these infants.

scholarly journals Effect of pterygium excision on mean corneal curvature.

2021 ◽  
Vol 28 (04) ◽  
pp. 568-571
Author(s):  
Saira Bano ◽  
Sumaya Khan ◽  
Mahnoor Waqar ◽  
Moniba Iqbal ◽  
Hamza Waqar Bhatti ◽  
...  
Keyword(s):  
P Value ◽  
Corneal Curvature ◽  
Ocular Surgery ◽  
Department Of Ophthalmology ◽  
Before And After ◽  
Quasi Experimental ◽  
History Of ◽  
Induced Astigmatism ◽  
Pterygium Excision ◽  
The Difference

Objective: To determine the difference in mean corneal curvatures before and after pterygium excision. Study Design: Quasi-experimental study. Setting: Department of Ophthalmology, Holy Family Hospital, Rawalpindi. Period: 1st January 2015 to 1st July 2015. Material & Methods: 68 patients aged between 18 to 65 years were included in the study. Patients with history of ocular trauma, ocular surgery, glaucoma, anti-glaucoma treatment, allergy to steroids, pseudo pterygium, recurrent pterygium and presence of corneal abnormalities such as, scarring that might affect the astigmatic value were excluded. All patients underwent comprehensive ophthalmic examination by slit lamp and best corrected visual acuity and keratometric values were noted. Pterygium excision was done by a single surgeon. BCVA and keratometric readings were taken again after 2 weeks of pterygium excision. Results: Mean age was 37.60 ± 11.11 years. Out of these 68 patients, 44 (64.71%) were male and 24 (35.29%) were females. Mean pre-operative corneal curvature was 2.99 ± 0.69D and post-operative corneal curvature was 1.70 ± 0.40D with P-value of <0.0001 which is statistically significant. Conclusion: This study concluded that pterygium excision brings significant change in corneal curvature in patients of pterygium induced astigmatism.

scholarly journals PEMBERIAN INFORMASI NEONATAL DEVELOPMENTAL CARE MENINGKATKAN SIKAP PERAWAT DALAM MERAWAT BBLR

2018 ◽  
Vol 5 (2) ◽  
pp. 106-112
Author(s):  
Anafrin Yugistyowati ◽  
Lia Endriyani
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Growth And Development ◽  
Nursing Intervention ◽  
Control Group ◽  
P Value ◽  
Developmental Care ◽  
Information Exposure ◽  
Before And After ◽  
Quasi Experimental

Newborn with low birth weight (LBW) in Indonesia is relatively high even up to 16,9 %. The role of the neonatal nurse is highly expected to provide care for newborn babies with LBW by giving supportive environment. Neonatal Developmental Care (NDC) is one of intervention that aims to implement modifications to the nursery environment and care practices to promote growth and development of newborn with LBW. Most of nurses still have no information related NDC and its implementation in neonatal room. This study aimed to explore the influence of NDC information exposure toward nurse’s attitude. A quasi-experimental with before-and-after design was applied. This study recruited 21 nurses to participate as intervention and control group. The Paired T-Test was performed to analyze the data. The results showed there is an influence of NDC information exposure toward nurse’s attitude in caring for newborn with low birth weight by P-value 0,00. This study recommend that NDC can be one of nursing intervention for caring newborn baby with LBW in order to optimize caring for infant along caring for growth and development during their treatment in hospital.

scholarly journals Efektivitas penyuluhan kesehatan dalam meningkatkan pengetahuan kader posyandu tentang pencegahan pneumonia pada balita

2018 ◽  
Vol 3 (1) ◽  
pp. 22
Author(s):  
Rapitos Sidiq
Keyword(s):  
P Value ◽  
Test Statistic ◽  
Health Seeking ◽  
Significance Level ◽  
Health Counseling ◽  
Work Area ◽  
Before And After ◽  
Seeking Behavior ◽  
Quasi Experimental

Kejadian Pneumonia pada balita masih menjadi permasalahan di dunia termasuk Indonesia. Banyak faktor yang melatarbelakangi kejadian penyakit ini, baik faktor lingkungan maupun perilaku manusia. Salah satu uapaya yang dilakukan untuk pencegahan penyakit ini adalah dengan peningkatan peran kader posyandu untuk kegiatan promotif dan preventif termasuk mempromosikan perilaku pencarian pertolongan kesehatan dan perawatan balita di rumah, sehingga setiap kader dituntut mengetahui tentang pencegahan pneumonia tersebut. Secara umu penelitian ini ingin melihat efektivitas penyuluhan kesehatan dalam meningkatkan pengetahuan kader posyandu tentang pencegahan penyakit pneumonia pada balita di wilayah kerja Puskesmas Darul Kamal Tahun 2017. Penelitian menggunakan metode quasi eksperimental dengan rancangan one group pretest-postest design. Jumlah sampel penelitian 30 orang. Uji statistic yang digunakan paired t-tes tingkat kemaknaan (α) 0,05 (5%). Penelitian ini menghasilkan nilai pengetahuan kader sebelum dan sesudah intervensi adalah 27,17:29,00 dengan p-value 0,003 (< 0,05). Penyuluhan kesehatan efektif dalam meningkatkan pengetahuan kader posyandu tentang pencegahan penyakit pneumoniaKata kunci:   Penyuluhan kesehatan, pengetahuan, kader posyandu, pneumonia, balita  ABSTRACTThe incidence of pneumonia in a toddler is still a problem in the world including Indonesia. Many factors caused the incidence of this disease, both environmental factors, and human behavior. One of the efforts undertaken for the prevention of this disease is by increasing the role of Health Post cadres for promotive and preventive activities including promoting health-seeking behavior and home toddler care so that each cadre is required to know about the prevention of pneumonia. In general, this research would like to see the effectiveness of health counseling in increasing the knowledge of health pos cadres on prevention of pneumonia disease in under-five children in the work area of Puskesmas Darul Kamal 2017. The study used quasi-experimental method with one group pretest-posttest design. The sample size is 30 people. Test statistic used paired t-test significance level (α) 0.05 (5%). This study yields cadre knowledge value before and after intervention is 27,17: 29,00 with p-value 0,003 (<0,05). Health counseling is effective in increasing knowledge of cadres about prevention of pneumonia disease.Keywords: Health counseling, knowledge, cadres, pneumonia, toddler

scholarly journals Aplikasi Web Cek Riska sebagai Upaya Meningkatkan Pengetahuan Ibu Mendeteksi Dini Risiko Tinggi Kehamilan

2020 ◽  
Vol 4 (1) ◽  
pp. 215-221
Author(s):  
Ni Luh Putu Martini ◽  
Irna Nursanti ◽  
Giri Widakdo
Keyword(s):  
High Risk ◽  
Experimental Design ◽  
Web Application ◽  
P Value ◽  
Group Design ◽  
Risk Pregnancy ◽  
Before And After ◽  
Quasi Experimental ◽  
The Mean ◽  
In Pregnancy

This study aimed to determine the effect of the risk checks web application on the knowledge of mothers to detect high risk early in pregnancy. The research design used in this study was a quasi-experimental design with one group design without control. The results showed that the mean difference before and after the intervention was 13.00, with a p-value of 0.000. In conclusion, the risk check web application can increase mothers' knowledge to detect high risk early in pregnancy.   Keywords: Web Application, High-Risk Pregnancy

scholarly journals Quality of the documentation of the Nursing process in clinical decision support systems

2021 ◽  
Vol 29 ◽  
Author(s):  
Neurilene Batista de Oliveira ◽  
Heloísa Helena Ciqueto Peres
Keyword(s):  
Decision Support ◽  
Clinical Decision Support ◽  
Clinical Decision Support Systems ◽  
Clinical Decision ◽  
P Value ◽  
Nursing Process ◽  
Post Intervention ◽  
Quasi Experimental ◽  
Process Documentation

Objective: to compare the quality of the Nursing process documentation in two versions of a clinical decision support system. Method: a quantitative and quasi-experimental study of the before-and-after type. The instrument used to measure the quality of the records was the Brazilian version of the Quality of Diagnoses, Interventions and Outcomes, which has four domains and a maximum score of 58 points. A total of 81 records were evaluated in version I (pre-intervention), as well as 58 records in version II (post-intervention), and the scores obtained in the two applications were compared. The interventions consisted of planning, pilot implementation of version II of the system, training and monitoring of users. The data were analyzed in the R software, using descriptive and inferential statistics. Results: the mean obtained at the pre-intervention moment was 38.24 and, after the intervention, 46.35 points. There was evidence of statistical difference between the means of the pre- and post-intervention groups, since the p-value was below 0.001 in the four domains evaluated. Conclusion: the quality of the documentation of the Nursing process in version II of the system was superior to version I. The efficacy of the system and the effectiveness of the interventions were verified. This study can contribute to the quality of documentation, care management, visibility of nursing actions and patient safety.

Sign in / Sign up

Export Citation Format

Share Document