scholarly journals Effect of secondhand smoke exposure on lung function among non-smoking population

2019 ◽  
Vol 6 (4) ◽  
pp. 1116
Author(s):  
Aravind C. ◽  
Ragul B. ◽  
Monisha .
Keyword(s):  
Lung Function ◽  
Secondhand Smoke ◽  
Smoking Status ◽  
Cross Sectional Study ◽  
Exposed Group ◽  
Analysis Of Covariance ◽  
Cross Sectional ◽  
Urinary Cotinine ◽  
Significant Difference ◽  
Shs Exposure

Background: Secondhand Smoke (SHS) exposure is known to be associated with various cardiovascular and respiratory problems but its effect on pulmonary function remains unexplored. This study was done to evaluate the effect of Secondhand Smoke (SHS) exposure on lung function among non-smoking population.Methods: This cross-sectional study was conducted in Bahour, Pondicherry from 2017-2018.  350 participants, age 40 year and older, with no respiratory symptoms or prior lung diseases were included in this study. Both self-reported history and measurement of urinary cotinine level were used to evaluate the smoking status. Spirometry data, including FVC and FEV1 were used to assess lung function. Diverse variables between groups were compared using T- test and Chi-square test. Analysis of covariance (ANCOVA) adjusted for age, height, alcohol consumption, and level of exercise was used to see any statistical differences in lung function parameters between non-SHS exposed and SHS-exposed groups.Results: Among 350 non-smokers, 120 were SHS-exposed. The urinary cotinine levels clearly distinguished SHS exposure, and the mean urinary cotinine levels were 7±0.3 and 11±0.4 in non-SHS exposed group vs SHS-exposed group, respectively. However, both groups had no significant difference in lung function and was found normal.Conclusions: SHS exposure urinary cotinine is a valuable marker.

scholarly journals Secondhand smoke (SHS) exposure before and after the implementation of the Tobacco Free Cities (TFC) initiative in five Chinese cities: a pooled cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e044570
Author(s):  
Zongshuan Duan ◽  
Yu Wang ◽  
Jidong Huang ◽  
Pamela B Redmon ◽  
Michael P Eriksen
Keyword(s):  
Secondhand Smoke ◽  
Smoking Status ◽  
Cross Sectional Study ◽  
Individual Characteristics ◽  
Cross Sectional ◽  
Media Campaigns ◽  
Chinese Cities ◽  
Before And After ◽  
Shs Exposure ◽  
Exposure Levels

ObjectivesTo assess the levels of secondhand smoke (SHS) exposure before and after the implementation of the Tobacco Free Cities (TFC) initiative.DesignCity-wide representative, cross-sectional surveys (Tobacco Questions for Surveys, TQS) were conducted in each participating city before and after the implementation of TFC.SettingFive large Chinese cities (Chengdu, Chongqing, Wuhan, Xiamen and Xi’an) participated in the TFC initiative.ParticipantsA total of 10 184 adults participated in the 2015 TQS survey, and 10 233 adults participated in the 2018 TQS survey, respectively.InterventionsThe TFC initiative, which included targeted media campaigns, educational programmes, implementing city-wide smoke-free policies and providing cessation interventions, was implemented in these five cities between 2015 and 2018.Main outcomeSelf-reported past 30-day (P30D) SHS exposure in indoor workplaces, restaurants and homes.Data analysisThe pre-TFC and post-TFC SHS exposure levels were compared among all residents and among certain population subgroups. Multivariate logistic regressions were used to estimate the adjusted associations between P30D SHS exposure and individual characteristics.ResultsAcross all five cities, the overall rate of self-reported P30D SHS exposure declined in indoor workplaces (from 49.6% (95% CI: 46.4% to 52.8%) to 41.2% (95% CI: 37.7% to 44.7%)), restaurants (from 72.4% (95% CI: 69.8% to 74.9%) to 61.7% (95% CI: 58.7% to 64.7%)) and homes (from 39.8% (95% CI: 36.9% to 42.7%) to 34.7% (95% CI: 31.5% to 37.8%)) from 2015 to 2018. These declines were statistically significant after controlling for individual characteristics. The P30D SHS exposure was associated with sex, age, education level, occupation and current smoking status. The associations varied by venues.ConclusionsOur analysis showed that compared with the nationwide SHS exposure levels reported in concurrent national surveys, the declines in P30D SHS exposure in five Chinese cities that implemented the TFC initiative were larger in indoor workplaces and restaurants. Our findings suggest that the TFC initiative was effective in reducing SHS exposure in Chinese cities.

scholarly journals Relationship between childhood secondhand smoke exposure and the occurrence of hyperlipidaemia and coronary heart disease among Chinese non-smoking women: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e048590
Author(s):  
Kewei Wang ◽  
Yuanqi Wang ◽  
Ruxing Zhao ◽  
Lei Gong ◽  
Lingshu Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Secondhand Smoke ◽  
Chinese Women ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Shs Exposure

ObjectiveThe objective of this study was to evaluate the influence of secondhand smoke (SHS) exposure during childhood on type 2 diabetes mellitus, hypertension, hyperlipidaemia and coronary heart disease among Chinese non-smoking women.MethodsIn this cross-sectional study, the SHS exposure data in childhood were obtained using a questionnaire survey. Self-reported childhood SHS exposure was defined as the presence of at least one parent who smoked during childhood.ResultsOf the 6522 eligible participants, 2120 Chinese women who had never smoked were assessed. The prevalence of SHS exposure in the entire population was 28.1% (596). SHS exposure during childhood was not significant for the standard risk factors of type 2 diabetes mellitus (p=0.628) and hypertension (p=0.691). However, SHS was positively associated with hyperlipidaemia (p=0.037) after adjusting for age, obesity, education status, physical activity, alcohol consumption, current SHS exposure status, diabetes mellitus and hypertension. In addition, childhood SHS increased the occurrence of coronary heart disease (p=0.045) among non-smokers after further adjusting for hyperlipidaemia.ConclusionSHS exposure during childhood is associated with prevalent hyperlipidaemia and coronary heart disease in adulthood among non-smoking Chinese women.

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals Comparison between objective measures of smoking and self-reported smoking status in patients with asthma or COPD: are our patients telling us the truth?

2015 ◽  
Vol 41 (2) ◽  
pp. 124-132 ◽  
Author(s):  
Rafael Stelmach ◽  
Frederico Leon Arrabal Fernandes ◽  
Regina Maria Carvalho-Pinto ◽  
Rodrigo Abensur Athanazio ◽  
Samia Zahi Rached ◽  
...  
Keyword(s):  
Smoking Status ◽  
Cross Sectional Study ◽  
The Self ◽  
Objective Measures ◽  
Cross Sectional ◽  
Current Smoking ◽  
Urinary Cotinine ◽  
Copd Patients ◽  
Asthma Patients ◽  
Cotinine Concentration

OBJECTIVE: Smoking prevalence is frequently estimated on the basis of self-reported smoking status. That can lead to an underestimation of smoking rates. The aim of this study was to evaluate the difference between self-reported smoking status and that determined through the use of objective measures of smoking at a pulmonary outpatient clinic. METHODS: This was a cross-sectional study involving 144 individuals: 51 asthma patients, 53 COPD patients, 20 current smokers, and 20 never-smokers. Smoking status was determined on the basis of self-reports obtained in interviews, as well as through tests of exhaled carbon monoxide (eCO) and urinary cotinine. RESULTS: All of the asthma patients and COPD patients declared they were not current smokers. In the COPD and asthma patients, the median urinary cotinine concentration was 167 ng/mL (range, 2-5,348 ng/mL) and 47 ng/mL (range, 5-2,735 ng/mL), respectively (p < 0.0001), whereas the median eCO level was 8 ppm (range, 0-31 ppm) and 5 ppm (range, 2-45 ppm), respectively (p < 0.05). In 40 (38%) of the patients with asthma or COPD (n = 104), there was disagreement between the self-reported smoking status and that determined on the basis of the urinary cotinine concentration, a concentration > 200 ng/mL being considered indicative of current smoking. In 48 (46%) of those 104 patients, the self-reported non-smoking status was refuted by an eCO level > 6 ppm, which is also considered indicative of current smoking. In 30 (29%) of the patients with asthma or COPD, the urinary cotinine concentration and the eCO level both belied the patient claims of not being current smokers. CONCLUSIONS: Our findings suggest that high proportions of smoking pulmonary patients with lung disease falsely declare themselves to be nonsmokers. The accurate classification of smoking status is pivotal to the treatment of lung diseases. Objective measures of smoking could be helpful in improving clinical management and counseling.

scholarly journals Smoking behaviours and indoor air quality: a comparative analysis of smoking-permitted versus smoke-free homes in Dhaka, Bangladesh

2020 ◽  
pp. tobaccocontrol-2020-055969
Author(s):  
Tarana Ferdous ◽  
Kamran Siddiqi ◽  
Sean Semple ◽  
Caroline Fairhurst ◽  
Ruaraidh Dobson ◽  
...  
Keyword(s):  
Low Cost ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Middle Income ◽  
A Value ◽  
Significant Difference ◽  
Proxy Measure ◽  
Shs Exposure ◽  
The Difference ◽  
Indoor Particulate Matter

IntroductionExposure to secondhand smoke (SHS) is a health risk to non-smokers. Indoor particulate matter (PM2.5) is associated with SHS exposure and is used as a proxy measure. However, PM2.5 is non-specific and influenced by a number of environmental factors, which are subject to geographical variation. The nature of association between SHS exposure and indoor PM2.5—studied primarily in high-income countries (HICs) context—may not be globally applicable. We set out to explore this association in a low/middle-income country setting, Dhaka, Bangladesh.MethodsA cross-sectional study was conducted among households with at least one resident smoker. We inquired whether smoking was permitted inside the home (smoking-permitted homes, SPH) or not (smoke-free homes, SFH), and measured indoor PM2.5 concentrations using a low-cost instrument (Dylos DC1700) for at least 22 hours. We describe and compare SPH and SFH and use multiple linear regression to evaluate which variables are associated with PM2.5 level among all households.ResultsWe surveyed 1746 households between April and August 2018; 967 (55%) were SPH and 779 (45%) were SFH. The difference between PM2.5 values for SFH (median 27 µg/m3, IQR 25) and SPH (median 32 µg/m3, IQR 31) was 5 µg/m3 (p<0.001). Lead participant’s education level, being a non-smoker, having outdoor space and smoke-free rule at home and not using kerosene oil for cooking were significantly associated with lower PM2.5.ConclusionsWe found a small but significant difference between PM2.5 concentrations in SPH compared with SFH in Dhaka, Bangladesh—a value much lower than observed in HICs.

Pulmonary Function Study in Female Grinders Exposed to Agate Dust

1990 ◽  
Vol 6 (1) ◽  
pp. 145-154 ◽  
Author(s):  
Subodh K. Rastogi ◽  
Brahma N. Gupta ◽  
Neeraj Mathur ◽  
Tanveer Husain ◽  
Prakash N. Mahendra
Keyword(s):  
Pulmonary Function ◽  
Complex Form ◽  
Cross Sectional Study ◽  
Exposed Group ◽  
Control Group ◽  
Cross Sectional ◽  
Radiologic Findings ◽  
Important Observation ◽  
Significant Difference ◽  
Exposed Workers

This paper reports a cross-sectional study of a non-smoking population of silica exposed female workers compared with a group of healthy non-exposed females. The exposed group is divided into cohorts according to the presence or absence of pneumoconiosis in either simple or complex form. The study revealed statistically significant difference in pulmonary function between each of the pneumoconiosis group and the controls and healthy exposed workers. Furthermore, there was statistically significant difference between the values of pulmonary function parameters of the healthy exposed group and the controls. The most important observation of the study is that almost equal decrement of pulmonary function values was observed in the diseased groups and in the healthy exposed group compared to the decrement seen between the latter group and the control group. VC and FVC showed a mean fall of 11.0 and 11.5% in the healthy exposed group as compared to those observed in the unexposed controls (p < 0.01 and p < 0.05) while in the pneumoconiosis group VC and FVC showed 16.9 and 18.2% decrease as compared with the values obtained in the healthy grinders (p < 0.01). Similarly FEV1 showed almost same decrease in the healthy (17.9%) and diseased (20.7%) exposed groups (p < 0.001). However, FEV0.75 and MVV parameters showed greater decrement (25.4 and 33.7%) in the pneumoconiosis group as compared to 15.7 and 18.5% observed in the healthy exposed workers. The important observation made in this study is that potential pulmonary debilitation may occur in pneumoconiosis before, or in the absence of, any radiologic findings.

scholarly journals Metabolic syndrome and lung function in Korean children and adolescents: A cross-sectional study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Minji Kim ◽  
Seoheui Choi ◽  
Soo-Han Choi ◽  
Seon-Hee Shin ◽  
Sung Koo Kim ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Lung Function ◽  
Children And Adolescents ◽  
Fasting Glucose ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Korean Children ◽  
Health And Nutrition ◽  
Significant Difference

Abstract This study aimed to investigate whether obesity and metabolic syndrome (MetS) are associated with pulmonary function in Korean children and adolescents. Data from the 2009–2011 Korea National Health and Nutrition Examination Survey which is cross-sectional, nationwide, and representative survey were used. Adjusted regression analysis was performed to evaluate the association of obesity and MetS with lung function in children and adolescents. A total of 763 children and adolescents aged 10–18 years were evaluated. We found no significant difference in FEV1% predicted, FVC% predicted, and FEV1/FVC ratio among the obesity groups. Subjects with MetS showed a significantly lower FEV1 predicted (91.54 ± 0.74% vs 94.64 ± 0.73%, P = 0.004), lower FVC% predicted (91.86 ± 0.63% vs 95.20 ± 0.63%, P < 0.001), and lower FEV1/FVC ratio (76.76 ± 0.43% vs 80.13 ± 0.43%, P < 0.001) than those without MetS. Elevated waist circumference (WC), systolic blood pressure, fasting glucose, and lower high-density lipoprotein cholesterol (HDL-C) were independently associated with lower FEV1/FVC ratio (all P < 0.05, respectively). Among MetS components, increased WC was the most important factor influencing lower FEV1/FVC ratio. In conclusion, lung function in MetS patients was significantly lower, and the MetS component was independently associated.

scholarly journals The prevalence of secondhand smoke exposure and related factors among schoolchildren in Northeast Thailand

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 1158
Author(s):  
Nirun Intarut ◽  
Piyalak Pukdeesamai
Keyword(s):  
Depressive Symptoms ◽  
Secondhand Smoke ◽  
Tobacco Consumption ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Related Factors ◽  
Cross Sectional ◽  
Depression Status ◽  
Chi Square Test ◽  
Shs Exposure

Background: The prevalence of tobacco consumption in Thailand has gradually declined; however, the prevalence of exposure to secondhand smoke (SHS) is still high. The objective of this study is to estimate the prevalence of SHS exposure and examine the association between exposure to SHS and depressive symptoms among schoolchildren, and test for moderation by the number of smokers in household. Methods: We conducted a cross-sectional study of 1105 schoolchildren. Socioeconomics factors, depressive symptoms and exposure to SHS variables were collected. We used the chi-square test for testing the factors associated to SHS exposure. In addition, we used the Mantel Haenszel test for testing interaction effect of depression to SHS exposure by the number of smokers in home. Multiple logistic regression was used to test the factors related to SHS exposure adjusted for confounders. Results: The prevalence of exposure to SHS was 58.2% (95%CI: 55.2, 61.1). The schoolchildren with abnormal depression status were 1.8 times more likely to have been exposed to SHS (95%CI: 1.3, 2.5). In addition, the number of smokers in the home did not modify the association between exposure to SHS and depressive symptoms (P: 0.964). Conclusions: An association between exposure to SHS and depressive in schoolchildren was observed, but this relationship was not affected by the number of smokers in children’s homes.

scholarly journals Genetic polymorphisms of the CYP1A1, GSTM1, and GSTT1 enzymes and their influence on cardiovascular risk and lipid profile in people who live near a natural gas plant

2017 ◽  
Vol 68 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Daria Pašalić ◽  
Natalija Marinković
Keyword(s):  
Cardiovascular Risk ◽  
Natural Gas ◽  
Lipid Profile ◽  
Genetic Polymorphisms ◽  
Smoking Status ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Framingham Risk ◽  
Genotype Frequencies ◽  
Significant Difference

Abstract The aim of this cross-sectional study was to see whether genetic polymorphisms of the enzymes CYP1A1, GSTM1, and GSTT1 are associated with higher risk of coronary artery disease (CAD) and whether they affect lipid profile in 252 subjects living near a natural gas plant, who are likely to be exposed to polycyclic aromatic hydrocarbons (PAHs). Fasting serum concentrations of biochemical parameters were determined with standard methods. Genetic polymorphisms of CYP 1A1 rs4646903, rs1048943, rs4986883, and rs1799814 were genotyped with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFPL), while GSTM1 and GSTT1 deletions were detected with multiplex PCR. Cardiovascular risk was assessed with Framingham risk score, and the subjects divided in two groups: >10% risk and ≤10% risk. The two groups did not differ in the genotype frequencies. MANCOVA analysis, which included lipid parameters, glucose, and BMI with sex, age, hypertension and smoking status as covariates, showed a significant difference between the GSTT1*0 and GSTT1*1 allele carriers (p=0.001). UNIANCOVA with same covariates showed that total cholesterol and triglyceride levels were significantly higher in GSTT1*1 allele carriers than in GSTT1*0 carriers (p<0.001 and p=0.006, respectively). Our findings suggest that CYP1A1, GSTM1, and GSTT1 polymorphisms are not associated with the higher risk of CAD, but that GSTT1 affects lipid profile.

scholarly journals Haematological Changes in Benzene Exposed Workers in Sudan

2020 ◽  
Author(s):  
Ahmed Mohammed Elnour Elkhalifa
Keyword(s):  
Complete Blood Count ◽  
Cross Sectional Study ◽  
Exposed Group ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Significant Difference ◽  
Exposed Workers ◽  
Comparative Group ◽  
Haematological Changes ◽  
Haematological Change

Abstract Background: Exposure to benzene leads to toxicity and influences bone marrow leads to cancer, anaemia, lymphoma, multiple myeloma, leukaemia, aplastic anaemia, and other types of cancer. The current study aims to report haematological changes in workers exposed to benzene exposure <1 ppm compared with the participants of non-exposed to benzene.Methods: Analytical cross-sectional study design applied at Kosti city, Sudan, during the year 2018. According to inclusion criteria, eighty-seven benzene stations workers chosen randomly to participate as a study group and another eighty-seven apparent healthy non-exposed to benzene, age matched, chosen as a comparative group. Blood samples (2.5ml) collected from all participants in EDTA anticoagulant containers for Complete Blood Cells analysis.Results: The means of the lymphocyte, RBCs count, and MCHC significantly increased in the benzene stations workers compared with the non-exposed group. The lymphocyte mean (44.61±8.41% vs, 29.19±3.98%; P<0.001), RBCs mean (5.30±0.75 ×1012 vs, 4.97±0.59 × 1012; P=0.002), and HCHC mean (32.67±2.12% vs, 31.71±1.37%; P<0.001). The means of PCV, Hb, MCH, MCV, PLTs count, Monocyte counts, and the Neutrophil counts significantly decreased in the exposed group. The PCV mean (43.83±2.47 l/l vs, 44.95±1.15 l/l; P<0.001), Hb mean (13.11±2.28 g/dl vs, 14.33±1.48 g/dl; P<0.001), MCH mean (26.35±2.01pg vs, 29.88±1.98pg; P<0.001), MCV mean (78.69±4.66 fl vs, 85.93±6.73 fl; P<0.001), PLTs mean (240.78±71.37×103/l vs, 262.54±70.77×103/l; P=0.046), Monocyte mean (4.44±2.39%vs. 5.64±1.92%; P=0.001), and Neutrophil mean (36.98±14.93% vs, 47.99±14.54%; P<0.001). The Eosinophil counts and TWBCs count showed no statistically significant difference between the two groups. Conclusion: The exposure to benzene has a significant haematological change in most of the complete blood count parameters among the benzene stations workers.

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