scholarly journals Oral cavity manifestations by COVID-19 infections: a review

Author(s):  
Santosh Kumar Swain ◽  
Priyanka Debta ◽  
Ansuman Sahu ◽  
Smarita Lenka

<p class="abstract">Coronavirus disease 2019 (COVID-19) is a threat to the global health caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The lungs are the primary site of infection in COVID-19 patient and the symptoms ranges from mild flu like manifestations to fulminant pneumonia and respiratory failure. COVID-19 infection also significantly affects the oral cavity and salivary glands with oral mucosal manifestations. Other than airway manifestations, COVID-19 patients are presenting with oral cavity lesions such as aphthous like ulcers, glossitis, oral mucositis or stomatitis, oral candidiasis and herpetic recurrences. These oral lesions are often associated with immunocompromised patients and elderly age. Direct involvement of the SARS-CoV-2 virus for development of oral ulcers remains uncertain. The salivary gland related symptoms and taste disturbances are highly common in COVID-19 patients. In COVID-19 patient, certain presentations like ulcers or blisters or diffuse reddish lesions affect both keratinized and non-keratinized tissues of the oral cavity. These lesions are found in palate, lip mucosa, buccal mucosa and tongue. The ulceration and blisters of the oral cavity are more often seen. There is still a gap of knowledge related to the oral manifestations of the COVID-19 infections and its impact on the oral cavity. This review article discussed the details of the oral cavity lesions in COVID-19 patients.</p>

2011 ◽  
Vol 05 (03) ◽  
pp. 291-298 ◽  
Author(s):  
Charles Mugisha Rwenyonyi ◽  
Annet Kutesa ◽  
Louis Muwazi ◽  
Isaac Okullo ◽  
Arabat Kasangaki ◽  
...  

ABSTRACTObjectives: To assess factors influencing the distribution of oral manifestations in HIV/AIDS-infected children attending the Paediatric Infectious Disease Clinic in Mulago Hospital, Kampala. Methods: This was a cross-sectional study comprising 237 children (males/females: 113/124) aged 1 to 12 years. The parents/guardians were interviewed to obtain demographic information, oral hygiene practices, dietary habits and health seeking behaviours as well as any medications taken. The children were clinically examined for oral lesions based on World Health Organization criteria with modifications. Results: About 71.7% of the children cleaned their teeth. About 16.9% of the children had visited a dentist since birth, mainly for emergency care. One or more oral lesions were recorded in 73% of the children of whom 19.0% experienced discomfort during oral functions. Cervical lymphadenopathy, oral candidiasis and gingivitis were the most common soft tissue oral lesions: 60.8%, 28.3% and 19.0%, respectively. Except for dental caries, the overall frequency distribution of soft tissue oral lesions was significantly lower in children on highly active antiretroviral therapy (HAART) as compared to their counterparts not on HAART. The prevalence of dental caries in deciduous and permanent dentitions was 42.2% and 11.0%, respectively. Tooth brushing and previous visits to the dentist were indirectly and significantly associated with dental caries. About 5.9% (n=14) of the children had <200 CD3 + CD4 T-lymphocyte cells per μl of blood. Conclusions: The majority of the children had one or more oral lesions, particularly in the group not on HAART. Some of the lesions were associated with discomfort during oral functions. (Eur J Dent 2011;5:291-298)


1989 ◽  
Vol 17 (1) ◽  
pp. 82-86 ◽  
Author(s):  
R. Rokicka-Milewska ◽  
D. Derulska ◽  
D. Lipnicki ◽  
A. Skrobowska-Woźniak ◽  
A. Moszczeńska

A total of 34 children with oral candidiasis were treated with 2.5% natamycin in the form of orally administered drops; 6–20 drops applied to oral lesions four times daily for up to 8 weeks. A total cure was achieved in 28 (82.3%) cases. No side-effects were observed. This preparation was an effective treatment for Candida albicans infections in children with blood diseases, and was well tolerated.


Author(s):  
Giulia Orilisi ◽  
Marco Mascitti ◽  
Lucrezia Togni ◽  
Riccardo Monterubbianesi ◽  
Vincenzo Tosco ◽  
...  

Background: COVID-19 disease first appeared in 2019 and quickly spread worldwide, causing a global pandemic. The oral cavity represents a target of SARS-CoV-2, and oral lesions are observed in both non-hospitalized and hospitalized patients. This systematic review aims to investigate the frequency of oral manifestations in COVID-19 hospitalized patients. Methods: An electronic search was conducted in PubMed, Scopus, and Web of Science databases, including articles published up to September 2021. The review protocol was based on PRISMA-P. The risk of bias of the studies was assessed using the Joana Briggs Institute. The certainty of evidence was assessed using the GRADE instrument. Results: Fifty-nine articles were included: 19 case reports, 17 case series, 2 case-control studies, 13 cross-sectional studies, 4 observational studies, and 4 retrospective studies. Oral ulcers, cheilitis, and tongue lesions were more common in patients before hospitalization, while perioral pressure ulcers, macroglossia, blisters, and oral candidiasis were more recurrent in patients during hospitalization. The first could be related directly to COVID-19, while the latter could be caused by medical devices, treatments, prone position, and immunological impairment. Conclusions: An accurate oral examination during the hospital admission of all confirmed COVID-19 cases is encouraged to recognize oral early manifestations and to apply appropriate treatments.


2019 ◽  
Author(s):  
Eter Bukhnikashvili ◽  
Mariam Tsintsadze ◽  
Nana Abashidze ◽  
Lia Jashi

The aim of our research was to detect the frequency of oral manifestations among the new revealed HIV-infected persons in 2013-2015. For this we studied the data from the center of AIDS, according to the testimony we studied those patients who needed stationary treatment and we got these results: In 2013 out of 490 new cases the presence of specific oral manifestations was found in 253(51.63 0.796%) patients. From whom we investigated 69 (27.270.61%) people. 45(65. 220. 45%) of them had oral candidiasis and 34(49.270.45%) disorders were caused by herpes-virus. In 2014 were revealed 564 new cases and the number of different concurrent intraoral lesions were found in 295(52.300.82%) patients. We investigated from them 146(49.490.66%) people and the result was next: 98 (67.120.32%) were different kinds of oral candidiasis and 54 (36.990.32%) diseases - caused by herpes-virus. In 2015 out of 717 new cases the HIV-associated oral manifestations were found in 381(53.130.86%) patients. We investigated 184(48.290.73%) people and as a result - 118 (64.130.46%) cases of them were oral candidiasis and 67(36.410.32%) were diseases caused by herpes-virus. According to the study it is obvious, that HIV-associated oral manifestations are met quite often among the HIV/ AIDS patients. It is very important to know specifications of these disorders, to make some right investigations and correct diagnosis in all situations, especially when it takes place HIV-associated oral lesions. Dentists should take in account the importance of instant diagnostic of oral manifestations in HIV/AIDS patients.


2021 ◽  
Vol 3 (1) ◽  
pp. 26-28
Author(s):  
Harneet Singh Mago ◽  
Annapurna Ahuja ◽  
Adreet Hazra ◽  
Alok Ratan Choudhary ◽  
Jagriti Basu ◽  
...  

COVID- 19 is a horrifying pandemic which affected all countries with significant involvement of population leaving the whole world helpless and in distress and grief. Scientists in the entire universe are working to get the healing solution to get rid of this terrific Corona Virus. Though vaccination against this infection has provided an apt relief but still the fight is on against the developing mutant stains. Numerous positive Covid cases have been presented with varied oral manifestations, which are important for dental surgeons to comprehend. The present review article highlighted oral lesions in patients with COVID- 19 disease.


2016 ◽  
Vol 17 (11) ◽  
pp. 943-947 ◽  
Author(s):  
KMK Masthan ◽  
E Vinesh ◽  
M Sathish Kumar ◽  
S Marytresa Jeyapriya ◽  
Aravindha Babu ◽  
...  

ABSTRACT Objectives The aim and objectives of this study are to identify oral changes in certain gastrointestinal (GI) diseases, namely gastroesophageal reflux disease (GERD), ulcerative colitis, gastritis, and to evaluate these oral symptoms as indicators for assessing GI disorders. Materials and methods In this study, the oral manifestations of various GI disorders were assessed in a varying age group of 250 patients in Government Stanley Medical College and Hospital, Chennai. Out of 250 patients, 142 were affected by GERD, 99 were affected by gastritis, and 9 patients were affected by ulcerative colitis. Of these patients, 177 were males and 73 were females. Results Evaluation of patients with gastritis revealed that 66.7% affected with gingivitis, 19.2% with dental erosion on the palatal and lingual aspects of maxillary and mandibular teeth predominantly in the anterior region, 10.1% with periodontitis, 2% with gingival erythema. Among the patients with GERD, 44% of the cases showed dental erosion, 25.5% periodontitis, 9.9% gingivitis, 5.7% gingival erythema, 2.8% palatal erythema, 2.1% gingival ulcers, glossitis 2%, 1.4% floor of the mouth erythema, and 0.7% erythema of the tongue. Patients with ulcerative colitis showed 44.4% of gingival erythema, 33.3% of dental erosions, and 22.2% of gingival ulcers and periodontitis. Conclusion In our study of 250 patients, oral manifestations were observed in 88% of the patients. Both soft tissue and hard tissue changes were evident. There was a high correlation between various GI disease and dental erosion, erythema at various sites of the oral cavity, oral ulcers, gingivitis, periodontitis, and glossitis. Careful evaluation of oral cavity may unveil many GI disorders and help the patient by providing early diagnosis, which further facilitates the prognosis. How to cite this article Vinesh E, Masthan KMK, Kumar MS, Jeyapriya SM, Babu A, Thinakaran M. A Clinicopathologic Study of Oral Changes in Gastroesophageal Reflux Disease, Gastritis, and Ulcerative Colitis. J Contemp Dent Pract 2016;17(11):943-947.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 969
Author(s):  
Hager Moustafa Saeed ◽  
Eman Mohammad Amr ◽  
Alshaimaa Rezk Lotfy Rezk ◽  
Wesam Abd Elmoneim

Background: Several systemic diseases manifest themselves in the oral cavity. Oral manifestations of lupus erythematosus (LE) are associated with a significantly increased risk of cancer. Dentists who are unaware of these lesions will possibly miss them. This cross-sectional study aimed to assess the prevalence of oral manifestations in patients with LE in a sample of the Egyptian population. Methods: A descriptive study was performed on 189 patients attending the Internal Medicine Department, Rheumatology Clinic in EL Qasr EL Ainy Hospital, Cairo University. Every patient was examined clinically after completing a questionnaire. Moreover, patients’ medical records were also evaluated.  The oral manifestations were recorded according to the WHO guide to physical examination of the oral cavity and classified according to their morphologic aspects and localization. Results: Out of 189 patients, there were 182 females (96.3%) and seven males (3.7%). The prevalence of oral lesions in LE patients was 55.6%. The most affected site was the tongue 25.7%. The most common clinical aspect was patches, 53%. About 77.1% of the lesions were asymptomatic. 74.3% of the patients had oral candidiasis. The prevalence of skin lesions in LE patients was 37.6%. The most common finding was malar rash 79%. Conclusions: The present study emphasizes the importance of early diagnosis of oral lesions to recognize patients with LE as the WHO considers oral manifestations of LE a widespread state associated with an increased risk of cancer. Also, implementation of oral hygiene measures and treatment to improve patients’ nutritional state and health-related quality of life are recommended.


2004 ◽  
Vol 51 (2) ◽  
pp. 103-106
Author(s):  
Ljiljana Markovic ◽  
Besir Ljuskovic

Crohn's disease is a chronic granulomatous inflammatory bowel disease of unknown cause. Segments of the whole gastrointestinal tract may be involved, including the oral cavity. The most common oral manifestations of Crohn's disease are edema, ulcerative and hyperplastic lesions. They appear most commonly on the lips, gingival tissue and buccal mucosa. Oral manifestations of Crohn's disease may precede intestinal symptoms. Recognition of these oral manifestations may lead to quicker diagnosis and earlier adequate treatment. If Crohn's disease is diagnosed, the dentist must make a detailed oral cavity examination and implement treatment of the existing oral lesions. Also, the dentist must provide prevention against caries and periodontal disease in these patients. Considering the frequency of oral manifestations of Crohn's disease, cooperation between gastroenterologist and dentist is very important.


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Diana Kuriachan ◽  
Rakesh Suresh ◽  
Mahija Janardhanan ◽  
Vindhya Savithri

Pemphigus is a group of potentially fatal dermatoses with both cutaneous and oral manifestations. Characterized by the appearance of vesicle or bullae, their manifestations in the oral cavity often precede those on the skin by many months or may remain as the only symptoms of the disease. It is therefore important that the oral manifestations of the disease are recognized on time, to make a proper diagnosis and initiate timely treatment. Here we present a case of Pemphigus Vulgaris (PV) that presented with oral lesions at multiple sites including tongue, to highlight the importance of timely recognition of the oral lesions during routine dental practice for the diagnosis and management of this disease.


Author(s):  

Objectives: Metastatic tumors to the oral cavity are observed extremely rarely, accounting for approximately 1% of all malignant oral lesions. The purpose of our study is to record and analyze the data of the patients who revealed metastasis to the oral cavity. Material and Methods: The records of the patients diagnosed with oral metastases who were admitted to Oral and Maxillofacial Surgery Departments from 1996 to 2018 were reviewed and analyzed for demographic data and outcomes. Results: Over a period of 22 years (from 1996 to 2018), 22 patients were admitted to the Oral and Maxillofacial Surgery Departments of General Hospital G. Papanikolaou and Theageneion Anticancer Hospital with oral metastasic tumors from a distant primary site. Conclusions: Metastasis to the oral cavity is a very rare finding but it exists so we have to be aware of it and have in mind the possibility of this condition.


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