scholarly journals Immune mediated Lesions of the oral cavity: A scrupulously researched review

2021 ◽  
Vol 7 (4) ◽  
pp. 238-244
Author(s):  
Sunita Gupta ◽  
Shriya Khera
Keyword(s):  
Oral Cavity ◽  
Clinical Features ◽  
Oral Mucosa ◽  
Signs And Symptoms ◽  
Review Article ◽  
Oral Lesions ◽  
Immune Mediated ◽  
Salient Features

Oral mucosa may be the first site to manifest protean signs and symptoms in immune mediated diseases. Therefore, it is of paramount importance to have a thorough and vast knowledge about various diseases. It is the role of Oral and Maxillofacial Diagnostician to diagnose the lesions according to their salient features.In this review article, we aim to describe the immune mediated oral lesions, their clinical features, investigations and management.

scholarly journals ORAL MANIFESTATIONS OF COVID-19: EARLY DIAGNOSTIC AID?

2020 ◽  
pp. 1-3
Author(s):  
Pooja Katira ◽  
Deep Shah ◽  
Falguni Maniyar
Keyword(s):  
Salivary Glands ◽  
Oral Mucosa ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Healthcare Services ◽  
Oral Lesions ◽  
Oral Manifestations ◽  
Global Pandemic ◽  
Clinical Signs And Symptoms ◽  
Taste And Smell

The outbreak of coronavirus disease which has rapidly escalated into a global pandemic continues to have disastrous health, economic and social effects on the human population. It has markedly affected the delivery of healthcare services all over the world. Early diagnosis of the disease is imperative to contain the spread of the viral infection. The main clinical signs and symptoms produced by SARS-CoV2 have been well described in the literature. However, there is emerging evidence on the oral lesions that may indicate the presence of COVID-19 infection. Since the virus has affinity for angiotensin converting enzyme (ACE2) receptors present in the respiratory tract, oral mucosa, tongue and salivary glands, the oral cavity serves as a major habitat for invasion of the virus. Thus, COVID-19 infection can affect the functioning of salivary glands, integrity of oral mucosa and can also cause alterations in sense of taste and smell. Good oral hygiene can decrease the incidence and severity of the main complications of COVID-19. The present review analyses the available evidence in relation to oral manifestations which are expressed in the course of the coronavirus disease and how it can aid in diagnosing the disease further.

scholarly journals Is SARS-CoV-2 an Etiologic Agent or Predisposing Factor for Oral Lesions in COVID-19 Patients? A Concise Review of Reported Cases in the Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Shahroo Etemad-Moghadam ◽  
Mojgan Alaeddini
Keyword(s):  
Signs And Symptoms ◽  
Skin Lesions ◽  
Etiologic Agent ◽  
Current Evidence ◽  
Oral Lesions ◽  
Predisposing Factor ◽  
Wide Range ◽  
Oral Symptoms ◽  
Indirect Association

The pathogenic mechanism of SARS-CoV-2 infection is unclear, and its symptoms vary in different patients. Initial reports of COVID-19 concentrated on pulmonary issues, but with time, additional features such as hyposmia/anosmia, dysgeusia, and skin lesions were added to the list of COVID-19 symptoms. There have been an increasing number of reports on oral cavity lesions in individuals with COVID-19, which might be relevant considering that this location is one of the first sites coming into contact with the virus and that it contains the SARS-CoV-2 receptor. We hereby aim to familiarize practicing head and neck clinicians with the range of oral lesions reported in COVID-19 patients and to critically appraise the most recent data on the role of SARS-CoV-2 in these lesions. We also discuss the ongoing debate on the direct/indirect association of oral symptoms with the disease. COVID-19 cases with simultaneous oral symptoms were extracted from the literature, and articles discussing the role of SARS-CoV-2 in oral lesions were compiled and methodically analyzed. We found approximately 95 COVID-19 patients with a wide range of oral lesions. Based on current evidence, the exact role of SARS-CoV-2 in the development of oral lesions remains unclear. Oral examination of patients is needed to provide adequate cases for analysis to clarify unknown problems related to COVID-19. There is evidence to support both the direct and indirect roles of SARS-CoV-2 in the development of oral lesions. Awareness of the possibility of oral manifestations in COVID-19 is important to clarify the range of disease signs and symptoms.

Role of Dentist in Diagnosis and Management of Mucormycosis in Association with COVID-19

2021 ◽  
Vol 11 (7) ◽  
pp. 159-163
Author(s):  
Piyush Dongre ◽  
Tanya Bansal
Keyword(s):  
Early Diagnosis ◽  
Fungal Infections ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Review Article ◽  
The Novel ◽  
Diagnosis And Management ◽  
Global Pandemic ◽  
Clinical Signs And Symptoms

In surge of the novel corona virus, there is increase in the frequency of fungal infections. Mucormycosis is one of the deep fungal infections which are increasing rapidly in this global pandemic period. Thus the early diagnosis and management is of utmost importance to decline the rate of this fatal infection. The clinical signs and symptoms and the culture reports are strictly considered in the management of oral fungal infection. This review article focuses on the importance of early diagnosis, prevention and management of mucormycosis and the role of the dentist in doing so. Key words: Mucormycosis, diagnosis, management, dentist.

scholarly journals PSYCHOSOMATIC ASPECTS OF THE COMBINED PATHOLOGY OF PERIODONTAL TISSUE AND ORAL MUCOSA

2018 ◽  
pp. 32-34 ◽  
Author(s):  
T.A. Petrushanko ◽  
N.N. Ilenko
Keyword(s):  
Oral Cavity ◽  
Oral Mucosa ◽  
The Body ◽  
Psychological Characteristics ◽  
Control Group ◽  
Periodontal Tissue ◽  
Dental Patients ◽  
Periodontal Tissues ◽  
Experimental Group

In the structure of modern diseases, there are 50-75% of psychosomatic diseases. To understand the role of the emotional factor in the onset and progression of somatic disorders, as well as the opposite process – the emergence of psychological and emotional disorders as a response to an acute or chronic disease of internal organs – acquires a particular importance and relevance at the present stage of the causality of the disease. Individual features of the response of the human body to social, biological factors have common mechanisms of combined damage to the mucous membrane of the oral cavity and periodontal tissue. The severity of the damage to these organs and tissues is also determined by the psychological characteristics of individuals. These points are important not only for understanding the causality of the combined pathology of the periodontal and oral mucosa, but also for choosing the optimal tactics for treating such dental patients. The aim of the work was to analyze the role of psychosomatic correlations in the occurrence and development of the combined pathology of the periodontal and oral mucosa, determining the tactics of their treatment. 32 patients were involved in the examination with pathological changes of periodontal and oral mucosa. The essential role of the emotional component in the genesis of diseases was confirmed. Taking into account the psychosomatic nature of the pathology in the experimental group of patients, recommendations were given on diet therapy, psychotherapy, autogenic training. General medical treatment for internists and dentists was maximally individualized, taking into account the psychological characteristics of the response to the disease, differentiated according to the nature of the existing diseases, severity, pathology. After 6 months of follow-up, a stable, reliable positive clinical result was obtained in all patients in the experimental group and in 64% in the control group. Accounting for the state of psychosomatic relationships in the mechanisms of origin, development, treatment of diseases is extremely important. This approach in the supervision of dental patients who have combined changes in periodontal tissues, the oral mucosa allows achieving positive results of treatment, both in relation to the condition of the oral cavity, and for the body as a whole.

scholarly journals The most important skin diseases of the sheep and the goat

2018 ◽  
Vol 51 (2) ◽  
pp. 107
Author(s):  
N. D. GIADINIS (Ν. Δ. ΓΙΑΔΙΝΗΣ) ◽  
M. N. SARIDOMICHELAKIS (Μ.Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ)
Keyword(s):  
Clinical Features ◽  
Skin Diseases ◽  
Small Ruminants ◽  
Review Article ◽  
Immune Mediated

Skin diseases of small ruminants may have an economical impact, apart from the fact that some of them can be transmitted to humans. In this review article, the most important environmental, nutritional, parasitic, bacterial, fungal, viral, immune-mediated and neoplastic skin diseases of the goat and sheep are presented, emphasising on the clinical features, the diagnosis and the treatment.

scholarly journals Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection

2021 ◽  
Vol 7 ◽  
Author(s):  
Giusy Rita Maria La Rosa ◽  
Massimo Libra ◽  
Rocco De Pasquale ◽  
Sebastiano Ferlito ◽  
Eugenio Pedullà
Keyword(s):  
Oral Cavity ◽  
Viral Infections ◽  
Current Knowledge ◽  
Coxsackie Virus ◽  
Oral Lesions ◽  
Cutaneous Manifestations ◽  
Associated Lesions ◽  
Immunodeficiency Virus ◽  
Indirect Action

Different viral agents, such as herpesviruses, human papillomavirus, and Coxsackie virus, are responsible for primary oral lesions, while other viruses, such as human immunodeficiency virus, affect the oral cavity due to immune system weakness. Interestingly, it has been reported that coronavirus disease 2019 (COVID-19) patients can show cutaneous manifestations, including the oral cavity. However, the association between oral injuries and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is still unclear. This narrative review aimed to summarize the available literature and provide an overview of oral lesions associated with COVID-19. An online literature search was conducted to select relevant studies published up to November 2020. The results of 17 studies showed variability in oral lesions associated with COVID-19, including ulcerations, aphthous-like lesions, and macules. The tongue, lips, and palate were the most frequent anatomical locations. According to current knowledge, the etiopathogenesis of multiple COVID-19-associated lesions seems to be multifactorial. The appearance of such lesions could be related to the direct or indirect action of SARS-CoV-2 over the oral mucosa cells, coinfections, immunity impairment, and adverse drug reactions. Nevertheless, COVID-19-associated oral lesions may be underreported, mainly due to lockdown periods and the lack of mandatory dispositive protection. Consequently, further research is necessary to determine the diagnostic and pathological significance of oral manifestations of COVID-19. All medical doctors, dentists, and dermatologists are encouraged to perform an accurate and thorough oral examination of all suspected and confirmed COVID-19 cases to recognize the disease's possible early manifestations.

scholarly journals Primary oral mucosa-associated lymphoid tissue (MALT) lymphoma in patient with monoclonale gammopathy: a rare case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hilal Hafian ◽  
Hubert Schvartz ◽  
Martine Patey ◽  
Anne Quinquenel
Keyword(s):  
Oral Cavity ◽  
Oral Mucosa ◽  
Malt Lymphoma ◽  
Monoclonal Gammopathy ◽  
Imaging Techniques ◽  
Clinical Signs ◽  
Biological Reality ◽  
Rare Case Report ◽  
History Of

Abstract Background Monoclonal gammopathy is a biological reality encountered in approximately 1% of the general population. In the absence of clinical and biological signs, it is considered of undetermined significance; however, it can be a biological signature of a monoclonal lymphocytic or plasma-cell proliferation. Their localisation to the oral mucosa remains rare and difficult to diagnose, particularly in indolent forms that escape imaging techniques. Case presentation Here, we report the case of a 73-year-old woman with a history of IgM kappa gammopathy followed for 13 years. The patient did not have a chronic infection or an autoimmune disease, and all the biological investigations and radiological explorations were unremarkable during this period. The discovery of a submucosal nodule in the cheek led to the diagnosis of MALT lymphoma and regression of half of the IgM kappa level after resection. The review of the literature shows the dominance of clinical signs (i.e., a mass or swelling) in the diagnosis of primary MALT lymphomas of the oral cavity after surgical resection. Conclusions Our case illustrates the role of examination of the oral cavity in the context of a monoclonal gammopathy. The absence of clinical and radiological evidence in favor of lymphoplasmacytic proliferation, does not exclude a primary indolent MALT lymphoma of the oral mucosa.

scholarly journals POSSIBLE ROLE OF NITRIC OXIDE IN REGULATION OF MICROCIRCULATION IN THE ORAL CAVITY TISSUES OF RAT

World Science ◽  
2019 ◽  
Vol 2 (2(42)) ◽  
pp. 4-9
Author(s):  
Dekanosidze M. ◽  
Saganelidze Kh. ◽  
Mamaladze M. ◽  
Sakvarelidze N. ◽  
Diasamidze G. ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Oral Cavity ◽  
Submandibular Gland ◽  
Oral Mucosa ◽  
Blood Circulation ◽  
Flow Regulation ◽  
Electrochemical Generation ◽  
Leading Role

Possible role of Nitric oxide (NO) in terms formation of basal blood flow level in oral cavity tissue is studied using the method of hydrogen electrochemical generation in anesthetized rats.It was found that NO plays a leading role in oral mucosa and submandibular gland basal blood flow regulation and does not have any significant effect on blood circulation of the lower snout tissue.

scholarly journals Relapsing Polychondritis: An Updated Review

Biomedicines ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 84 ◽  
Author(s):  
Francesco Borgia ◽  
Roberta Giuffrida ◽  
Fabrizio Guarneri ◽  
Serafinella Cannavò
Keyword(s):  
Diagnostic Criteria ◽  
Clinical Features ◽  
Functional Impairment ◽  
Clinical Presentation ◽  
Systemic Disease ◽  
Relapsing Polychondritis ◽  
Review Article ◽  
Therapeutic Options ◽  
Immune Mediated ◽  
Specific Symptoms

Relapsing polychondritis is an immune-mediated systemic disease characterized by recurrent episodes of inflammation of cartilaginous and proteoglycan-rich tissues, resulting in progressive anatomical deformation and functional impairment of the involved structures. Auricular and nasal chondritis and/or polyarthritis represent the most common clinical features, but potentially all types of cartilage may be involved. Because of the pleomorphic nature of the disease, with non-specific symptoms at the onset, the diagnosis of relapsing polychondritis is often delayed. In this review article we provide a comprehensive look into clinical presentation, laboratory and instrumental investigations, diagnostic criteria, and therapeutic options.

scholarly journals Oral findings in SARS-CoV-2 infection- A comprehensive review

2022 ◽  
Vol 7 (4) ◽  
pp. 208-210
Author(s):  
Kratika Mohan ◽  
G V Sowmya ◽  
Shashwat Saxena ◽  
Samia Seraj
Keyword(s):  
Quality Of Life ◽  
Signs And Symptoms ◽  
Oral Lesions ◽  
Health It ◽  
Comprehensive Review ◽  
Global Pandemic ◽  
Dental Practitioners ◽  
Multi Disciplinary Team

The COVID-19 has presented as a worldwide threat to global health. It is highly necessary to study signs and symptoms associated with this infection. This review highlights the role of dental practitioners to diagnose the early signs of oral lesions in COVID-19 infection. They can play an important role in managing pain, giving support to patient and improving the quality of life, by becoming a part of multi-disciplinary team to fight against this global pandemic.

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