scholarly journals Herbal mouthwashes for oral health care-A paradigm shift

2021 ◽  
Vol 8 (3) ◽  
pp. 100-102
Author(s):  
Pavita Kataria ◽  
Harpreet Singh ◽  
Davinderjit Kaur Shergill
Keyword(s):  
Dental Health ◽  
Oral Care ◽  
Aloe Vera ◽  
Herbal Medicines ◽  
Gingival Inflammation ◽  
Herbal Products ◽  
Cleaning Agents ◽  
Tooth Cleaning ◽  
Review Study ◽  
And Control

Herbs have been used since centuries to prevent and control various diseases. Being low in cost, safe, and easily available, herbal medicines are staging a comeback globally, owing to their antimicrobial, antifungal, anti-inflammatory, and anti-carcinogenic properties. In dentistry, herbal extracts have been widely used in tooth cleaning agents and mouthrinses. The present study is aimed at reviewing various extracts of herbal products and their effects on dental health. From this review study, it is evidenced that Aloe vera, Neem, Clove Oil, Castor Oil, and Peppermint showed better results than conventional mouthwashes in dental plaque and gingival inflammation reductions. However, preclinical and clinical trials are needed to gauge biocompatibility and safety before herbal medicines are often recommended conclusively for oral care.

Secondary Metabolites in the Treatment of Diabetes Mellitus: A Paradigm Shift

2020 ◽  
Vol 21 (7) ◽  
pp. 493-511
Author(s):  
Deependra Singh Chauhan ◽  
Paras Gupta ◽  
Faheem Hyder Pottoo ◽  
Mohd Amir
Keyword(s):  
Diabetes Mellitus ◽  
Secondary Metabolites ◽  
Biomarker Discovery ◽  
Aloe Vera ◽  
Significant Activity ◽  
Herbal Products ◽  
Metabolic Markers ◽  
And Control

Diabetes mellitus (DM) is a chronic, polygenic and non-infectious group of diseases that occurs due to insulin resistance or its low production by the pancreas and is also associated with lifelong damage, dysfunction and collapse of various organs. Management of diabetes is quite complex having many bodily and emotional complications and warrants efficient measures for prevention and control of the same. As per the estimates of the current and future diabetes prevalence, around 425 million people were diabetic in 2017 which is anticipated to rise up to 629 million by 2045. Various studies have vaguely proven the fact that several vitamins, minerals, botanicals and secondary metabolites demonstrate hypoglycemic activity in vivo as well as in vitro. Flavonoids, anthocyanin, catechin, lipoic acid, coumarin metabolites, etc. derived from herbs were found to elicit a significant influence on diabetes. However, the prescription of herbal compounds depend on various factors, including the degree of diabetes progression, comorbidities, feasibility, economics as well as their ADR profile. For instance, cinnamon could be a more favorable choice for diabetic hypertensive patients. Diabecon®, Glyoherb® and Diabeta Plus® are some of the herbal products that had been launched in the market for the favorable or adjuvant therapy of diabetes. Moreover, Aloe vera leaf gel extract demonstrates significant activity in diabetes. The goal of this review was to inscribe various classes of secondary metabolites, in particular those obtained from plants, and their role in the treatment of DM. Recent advancements in recognizing the markers which can be employed for identifying altered metabolic pathways, biomarker discovery, limitations, metabolic markers of drug potency and off-label effects are also reviewed.

scholarly journals Carcinogenic herbs: a review

2019 ◽  
Vol 7 (2) ◽  
pp. 649
Author(s):  
Ishan Tewari ◽  
Prashant Shukla ◽  
Vijay K. Sehgal
Keyword(s):  
Adverse Events ◽  
Ginkgo Biloba ◽  
Aloe Vera ◽  
Herbal Medicines ◽  
Medicinal Herbs ◽  
Herbal Products ◽  
Kava Kava ◽  
Ancient Times

Herbal toxicity is a field that has rapidly grown over the last few years along with increased use of herbal products worldwide. People prefer using herbal medicines rather than allopathic because herbals are considered safe. Use of herbal medicines from ancient times does not ensure their complete safety. With the growing awareness regarding pharmacovigilance worldwide, there has been an increase in the number of reported adverse events occurring with the use of herbal products. The objective of the study is to aware the researchers about most commonly used Indian medicinal herbs inducing carcinogenicity like Aloe vera, Ginkgo biloba, Kava kava, etc. 

scholarly journals Medicinal Plants Effective in the Prevention and Control of Coronaviruses

2021 ◽  
Vol 10 (4) ◽  
pp. 296-307
Author(s):  
Saghar Ketabchi ◽  
◽  
Maryam Papari Moghadamfard ◽  
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Aloe Vera ◽  
Common Mechanism ◽  
Purple Coneflower ◽  
Antiviral Effects ◽  
Grapefruit Peel ◽  
Review Study ◽  
The One ◽  
And Control

Objective: Coronaviruses often cause acute complications in the respiratory system with cold-like symptoms. A number of them, such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) and Coronavirus Disease 2019 (COVID-19) have killed thousands of people and have caused epidemics and pandemics. This review study aims to investigate the most common medicinal plants in Iran and introduce their natural products with antiviral effects on coronaviruses and strengthening the immune system in order to prevent and control them. Methods: In this review study, a search was conducted in national and international databases such as Web of Science, Scopus, PubMed, Science Direct, Google Scholar, SID, MagIran and IranMedex by using keywords such as COVID-19, Coronaviruses, SARS, MERS, SARS-CoV-2, PEDV in both Persian and English for studies published until 2020, and finally 51 articles were selected. Results: There are 10 plants with antiviral effects on members of the family Coronaviridae among which Ginger, Galangal, Cinnamon, Fennel flower, Grapefruit (peel), and Purple coneflower were effective on COVID-19. Elder, Ginseng, Aloe vera, Milkvetch, and Shirazi Thyme plants were effective in boosting the immune system and preventing viral diseases. Conclusion: Inhibiting the replication of viruses is the common mechanism in antiviral drugs, but natural compounds usually counteract it by disrupting key proteins and virulence factors of viruses. Therefore, the use of the antiviral components of reported plants can be useful in producing drugs for these viruses, especially the one causing COVID-19.

scholarly journals Herbal medicines in the treatment of coronavirus disease 2019 (COVID-19)

2020 ◽  
Vol 10 (2) ◽  
pp. e18-e18
Author(s):  
Audrey Tolouian ◽  
Maryam Khosravian ◽  
Hedieh Ragati Haghi ◽  
Alireza Bolourian ◽  
Zahra Mojtahedi ◽  
...  
Keyword(s):  
Viral Infections ◽  
Healthy Lifestyle ◽  
Herbal Medicines ◽  
Personal Hygiene ◽  
The Novel ◽  
Herbal Products ◽  
The Third ◽  
Novel Virus ◽  
Novel Coronavirus ◽  
And Control

Coronavirus disease 2019 (COVID-19), caused by a novel coronavirus, started in livestock within the markets of Wuhan, China and was consequently spread around the world. The virus has been rapidly spread worldwide due to the outbreak. COVID-19 is the third serious coronavirus outbreak in less than 20 years after Severe Acute Respiratory Syndrome (SARS) in 2003 and Middle East Respiratory Syndrome (MERS) in 2012. The novel virus has a nucleotide identity closer to that of the SARS coronavirus than that of the MERS coronavirus. Since there is still no vaccine, the main ways to improve personal immunity against this disease are prophylactic care and self-resistance including an increased personal hygiene, a healthy lifestyle, an adequate nutritional intake, a sufficient rest, and wearing medical masks and increasing time spent in well ventilated areas. There is a need for novel antivirals that are highly efficient and economical for the management and control of viral infections when vaccines and standard therapies are absent. Herbal medicines and purified natural products have the potential to offer some measure of resistance as the development of novel antiviral drugs continues. In this review, we evaluated 41 articles related to herbal products which seemed to be effective in the prevention or treatment of COVID-19.

Aspects of Oral Health in Orthodontic Patients

1986 ◽  
Vol 13 (2) ◽  
pp. 95-103 ◽  
Author(s):  
N. Pender
Keyword(s):  
Oral Health ◽  
Oral Care ◽  
First Year ◽  
Gingival Inflammation ◽  
Full Data ◽  
Fixed Appliance ◽  
Tooth Cleaning ◽  
Orthodontic Patients ◽  
Removable Appliance ◽  
Removable Appliances

A longitudinal and transverse study has been carried out on 22 orthodontic patients during their first year of treatment to assess levels of plaque control and gingival inflammation. The scores were of full data and the patients randomly arranged on a split mouth cross-over design to study the effects of patient oral care and selective tooth cleaning on levels of oral health. The results are analysed in respect of upper fixed, lower fixed and upper removable appliances, comparing and contrasting quadrants that have been treated differently. Plaque levels appear constant, whereas levels of gingival inflammation are consistently worse during treatment but only in certain areas of the mouth. Levels of plaque and gingivitis are well controlled. There appears to be no hygiene disadvantage to an upper removable appliance when compared with an upper fixed appliance though the effect differs in relation to the tooth aspect considered. The significance of the findings is discussed.

Mikroalgák mint természetes hatóanyagforrások

2018 ◽  
Vol 159 (18) ◽  
pp. 703-708
Author(s):  
Gábor Vasas
Keyword(s):  
Mass Production ◽  
Higher Plants ◽  
Herbal Medicines ◽  
Point Of View ◽  
Historical Background ◽  
Herbal Products ◽  
Chlorella Sp ◽  
Economic Significance ◽  
Preclinical And Clinical Studies ◽  
Microalgal Species

Abstract: More than 90% of herbal products and herbal medicines have been derived from higher plants recently, but due to independent circumstances, several photosynthetic microalgal species are in focus in this point of view. In the last 50 years, many carbohydrate-, peptide-, terpenoid-, alkaloid- and phenol-type components were described from algae because of the developing structural determination and analytical methods, algae mass production and also artificial algae technologies. At the same time, based partly on traditional causes and partly on the clinical and preclinical data of today, some dried products of algae are directly used as food supplements. Hereinafter, the historical background, economic significance and metabolic background of the mostly used microalgal species will be reviewed. The diverse metabolite production of these organisms will be demonstrated by some molecules with special bioactivity. Several preclinical and clinical studies will be described relating to the microalgal species Spirulina sp., Chlorella sp., Haematococcus sp. and Dunaliella sp. Orv Hetil. 2018; 159(18): 703–708.

Herbal Products for Common Auto-Inflammatory Disorders - Novel Approaches

2018 ◽  
Vol 21 (3) ◽  
pp. 161-174 ◽  
Author(s):  
Shanoo Suroowan ◽  
Fawzi Mahomoodally
Keyword(s):  
Adverse Effects ◽  
Chronic Conditions ◽  
Herbal Medicines ◽  
Review Article ◽  
Herbal Products ◽  
Inflammatory Disorders ◽  
Treatment Regimens ◽  
Synthetic Agents ◽  
Unique Approach ◽  
Novel Approaches

Background: Common auto-inflammatory disorders (CAIDs) constitute a wide array of ailments ranging from acute allergies to chronic conditions. Globally, CAIDs remain one of the leading causes of disability and morbidity. Despite playing a leading therapeutic role, the vast profusion of anti-inflammatory synthetic agents have not been able to fully resolve a panoply of CAIDs. Additionally, contemporary synthetic therapy approaches remain bounded by a wide array of limitations essentially being adverse effects and unaffordable costs. In this advent, the use of herbal products provides an interesting avenue to explore in view of developing such treatment regimens. Objective: This review article endeavors to highlight potential herbal products and isolated phytochemicals which can be of benefit in the prophylaxis, management, and treatment alongside avoiding the relapse of CAIDs. Conclusion: This review article has highlighted that herbals, herbal products, and isolated metabolites hold a huge potential in the prophylaxis, management, and treatment of CAIDs. Herbals can act on various targets involved in the pathogenesis of inflammatory disorders. In addition, novel approaches for the management of CAIDs are numerous. Indeed, nanoparticles loaded with phytochemicals have been developed to specifically target the colon for IBD treatment. In silico approaches using herbals also offer unlimited avenues to decipher new pharmacophores. Investigating the potential of polyherbal formulations is another unique approach which can be investigated. Given the inefficacy of conventional medicines, the concomitant use of conventional and herbal medicines can also be explored.

scholarly journals Nephrotoxicity of Herbal Products in Europe—A Review of an Underestimated Problem of Nephrotoxicity of Herbal Products

2021 ◽  
Vol 22 (8) ◽  
pp. 4132
Author(s):  
Katarzyna Kiliś-Pstrusińska ◽  
Anna Wiela-Hojeńska
Keyword(s):  
Kidney Diseases ◽  
Herbal Medicines ◽  
Kidney Injury ◽  
Herbal Products ◽  
Chronic Kidney Diseases ◽  
European Origin ◽  
Synthetic Drugs ◽  
The Many ◽  
Pharmacologically Active ◽  
Traditional Chinese Herbal Medicines

Currently in Europe, despite the many advances in production technology of synthetic drugs, the interest in natural herbal medicines continues to increase. One of the reasons for their popular use is the assumption that natural equals safe. However, herbal medicines contain pharmacologically active ingredients, some of which have been associated with adverse effects. Kidneys are particularly susceptible to injury induced by toxins, including poisonous constituents from medicinal plants. The most recognized herb-induced kidney injury is aristolochic acid nephropathy connected with misuse of certain Traditional Chinese herbal medicines. Data concerning nephrotoxicity of plant species of European origin are scarce. Here, we critically review significant data of the nephrotoxicity of several plants used in European phytotherapy, including Artemisia herba-alba, Glycyrrhiza glabra, Euphorbia paralias, and Aloe). Causative mechanisms and factors predisposing to intoxications from the use of herbs are discussed. The basic intention of this review is to improve pharmacovigilance of herbal medicine, especially in patients with chronic kidney diseases.

Oral Aloe Vera-Induced Hepatitis

2007 ◽  
Vol 41 (10) ◽  
pp. 1740-1743 ◽  
Author(s):  
Michelle M Bottenberg ◽  
Geoffrey C Wall ◽  
Roger L Harvey ◽  
Shahid Habib
Keyword(s):  
Acute Hepatitis ◽  
Safety Information ◽  
Aloe Vera ◽  
Assessment Method ◽  
Prescription Medications ◽  
Medication History ◽  
Herbal Products ◽  
Number Of Patients ◽  
The Us ◽  
Liver Markers

Objective: To report a case of possible oral aloe vera-induced hepatitis. Case Summary: A 73-year-old female was admitted to the hospital for acute hepatitis. Extensive laboratory testing did not reveal the cause of the patient's disease. She was asked multiple times whether she was taking any home medications, which she initially denied. It was only after an extensive medication history done by a clinical pharmacist that the patient admitted to using oral aloe vera capsules for constipation. Upon discontinuation of the oral aloe vera, liver markers of hepatotoxicity returned to normal levels. Discussion: Herbal medications pose an increasing problem in patient safety, as the different types of these products and the number of patients who use them continue to grow. In the US, these products are not subject to the same regulatory scrutiny as prescription medications; thus, safety information can be difficult to obtain. In particular, hepatic toxicity due to herbal agents is poorly described in the medical literature. Aloe vera, often used topically for minor burns, can also be used orally as a laxative or an “anti-aging” agent. According to the Naranjo probability scale, the hepatotoxicity in this case was possibly related to ingestion of oral aloe vera. Additionally, using the Roussel Uclaf Causality Assessment Method for determining drug hepatotoxicity, the patient's symptoms were scored as probably caused by oral aloe vera. The more conservative designation was used in our report. Conclusions: With the widespread use of oral aloe vera and other herbal products, clinicians faced with a case of acute hepatitis that is not readily diagnosed should question patients about herbal use.

Herbal Remedies and Children: Do They Work? Are They Harmful?

PEDIATRICS ◽  
2003 ◽  
Vol 112 (Supplement_1) ◽  
pp. 240-246 ◽  
Author(s):  
Alan D. Woolf
Keyword(s):  
Primary Care ◽  
Herbal Medicine ◽  
Herbal Medicines ◽  
Good Health ◽  
Herbal Remedies ◽  
Herbal Products ◽  
Safety And Efficacy ◽  
Primary Care Clinicians

More parents are considering the use of herbal remedies to maintain their children’s good health and to treat their illnesses. They look to pediatricians and other primary care clinicians for advice concerning the safety and efficacy of herbal products for children. This article reviews principles for the clinician to keep in mind while investigating the literature on herbal medicine and addressing the use of herbal medicines with parents.

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