scholarly journals  Phytochemical ingredients and pharmacological potential of Calendula officinalis Linn. 

2018 ◽  
Author(s):  
Pawan Kumar Verma ◽  
Rajinder Raina ◽  
Sanjay Agarwal ◽  
Harpreet Kour
Keyword(s):  
Economic Value ◽  
Pharmaceutical Preparations ◽  
Modern Medicine ◽  
Biologically Active ◽  
Calendula Officinalis ◽  
Scientific Database ◽  
Traditional Medicines ◽  
Botanical Description ◽  
History Of ◽  
Pharmacological Potential

  Calendula officinalis Linn. commonly known as marigold has long history of usage by the folklore system. It has a high economic value as herbal medicine and is widely used in cosmetics, perfumes, dyes, pharmaceutical preparations and food products for centuries. The plant has been approved for food use and appears in the food and drug administration (FDA) list of generally recognized as safe (GRAS) substances. The literature available for the comprehensive review study were taken from the different worldwide accepted scientific database, journals, books for botanical description, pharmacological properties and ethno-botanical uses of C. officinalis Linn. Natural products containing calendula either as extract or oil are complex mixtures containing hundreds of biologically active constituents such as carotenoids, flavonoids, saponins, sterols, phenolic acids, lipids, amino acids, carbohydrates, etc. These phytoconstituents have wide applicability in food and cosmetic industries besides their therapeutic applications viz. as antioxidant, antimicrobial, anti-inflammatory, anti-ulcer, anti-proliferative, antiparasitic, hypoglycemic, hypolipidemic and wound healing potential in experimental and clinical trials. Being useful therapeutic agents in their own right, an understanding of these traditional medicines has provided new plant derived drug leads to modern medicine for therapeutic application.

scholarly journals HISTORY OF INDIAN TRADITIONAL MEDICINE: A MEDICAL INHERITANCE.

2018 ◽  
Vol 11 (1) ◽  
pp. 421 ◽  
Author(s):  
Partha Pradip Adhikari ◽  
Satya Bhusan Paul
Keyword(s):  
Traditional Medicine ◽  
Web Search ◽  
Care Service ◽  
Health Care Service ◽  
Modern Medicine ◽  
Traditional Medicines ◽  
Regional Effects ◽  
Practice Of Medicine ◽  
History Of ◽  
Traditional Approaches

 Objective: Indian Traditional Medicine, the foundation of age-old practice of medicine in the world, has played an essential role in human health care service and welfare from its inception. Likewise, all traditional medicines are of its own regional effects and dominant in the West Asian nations; India, Pakistan, Tibet, and so forth, East Asian nations; China, Korea, Japan, Vietnam, and so forth, Africa, South and Central America. This article is an attempt to illuminate Indian traditional medical service and its importance, based on recent methodical reviews.Methods: Web search engines for example; Google, Science Direct and Google Scholar were employed for reviews as well as for meta-analysis.Results: There is a long running debate between individuals, who utilize Indian Traditional Medicines for different ailments and disorders, and the individuals who depend on the present day; modern medicine for cure. The civil argument between modern medicine and traditional medicines comes down to a basic truth; each person, regardless of education or sickness, ought to be educated about the actualities concerning their illness and the associated side effects of medicines. Therapeutic knowledge of Indian traditional medicine has propelled various traditional approaches with similar or different theories and methodologies, which are of regional significance.Conclusion: To extend research exercises on Indian Traditional Medicine, in near future, and to explore the phytochemicals; the current review will help the investigators involved in traditional medicinal pursuit.

scholarly journals Usage of Mushrooms in Culinary and Medicinal Purposes

2022 ◽  
Vol 6 (1) ◽  
pp. 01-07
Author(s):  
Mohammad Azizur Rahman ◽  
Tawhidur Rahman ◽  
Moshiur Rahman ◽  
Mirza Arif
Keyword(s):  
Nutritional Value ◽  
Radical Scavenging ◽  
Modern Medicine ◽  
Free Radical Scavenging ◽  
Biologically Active ◽  
Current Status ◽  
The World ◽  
Future Aspect ◽  
History Of ◽  
Distinct Role

The present article reviews the history of mushroom uses in culinary, food and medicinal values; current status and future aspect of mushroom research. Mushrooms contain biologically active polysaccharides, lipid and proteins in fruit bodies, each of them has a distinct role in health as either nutritional value or medicinal elements. Immunostimulating polysaccharides found in mushrooms, are most important for modern medicine. Several of the mushroom biomolecules have undergone phase I, II, and III clinical trials and are used extensively and successfully throughout the world for the treatment of various cancers and other diseases. Medicinal functions played by the mushrooms include antitumor, antibacterial, antioxidant, antiparasitic, antidiabetic, detoxification, cardiovascular, antihypercholesterolemia, antiviral, antifungal, hepatoprotective, immunomodulating and free radical scavenging. The present review draws attention to nutritional and medicinal importance of mushroom as well as the problems and opportunity in the future development of mushroom research.

Phytochemical, pharmacological and clinical studies of petasites hybridus (l.) P. Gaertn., B. Mey. & Scherb. A review /

2013 ◽  
Vol 59 (4) ◽  
pp. 108-128 ◽  
Author(s):  
Marcin Ożarowski ◽  
Jędrzej Przystanowicz ◽  
Artur Adamczak
Keyword(s):  
Clinical Studies ◽  
Pyrrolizidine Alkaloids ◽  
Folk Medicine ◽  
Biologically Active ◽  
Future Application ◽  
Migraine Treatment ◽  
Toxicological Studies ◽  
Botanical Description ◽  
History Of ◽  
History Of Use

Abstract Preparations from rhizomes of Petasites hybridus (L.) Gaertn., B. Mey. & Scherb. (common butterbur) have a long history of use in folk medicine in treatment of several diseases as anti-inflammatory and spasmolytic drugs. Extracts from this species are of interest to researchers in the field of phytopharmacology due to their biologically active compounds, particularly two eremophilane sesquiterpenes (petasin and isopetasin), which are contained not only in rhizomes and roots, but also in leaves. Moreover, P. hybridusa contains pyrrolizidine alkaloids, which showed hepatotoxic, carcinogenic and mutagenic properties. Hence, special extracts devoid of alkaloids obtained by sub- and super-critic carbon dioxide extraction were used in the preclinical, clinical studies and phytotherapy. Our review aims to provide a literature survey of pharmacological as well as clinical trials of P. hybridus, carried out in 2000-2013. Also several studies of other species used in non-European countries have been included. Besides, the botanical description of Petasites genus and phytochemical characteristic of P. hybridus and toxicological studies of pyrrolizidine alkaloids as well as chemical profile of patented commercial extracts from rhizomes, roots and leaves of this species used in European phytotherapy have been performed. In this review, attention has also been paid to the promising and potential application of special extracts of P. hybridus not only in the prevention of migraine, treatment of allergic rhinitis symptoms, asthma and hypertension, but also in prevention and slowing the progression of neurodegenerative diseases developing with the inflammatory process in the CNS as a new therapeutic strategy. In fact, there is already an evidence of promising properties of P. hybridus extracts and sesquiterpens - decrease in the prostaglandins and leukotrienes release, inhibition of COX-1 and COX-2 activity, as well as antagonism of L-type voltage-gated calcium channels. In order to explain the new mechanisms of action of P. hybridus extracts in the CNS and their future application in phytotherapy of diseases with neuroinflammatory process, further studies should be performed.

scholarly journals GenusTinospora: Ethnopharmacology, Phytochemistry, and Pharmacology

2016 ◽  
Vol 2016 ◽  
pp. 1-32 ◽  
Author(s):  
Sensen Chi ◽  
Gaimei She ◽  
Dan Han ◽  
Weihua Wang ◽  
Zhao Liu ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Current Knowledge ◽  
Biological Activities ◽  
Modern Medicine ◽  
Convincing Evidence ◽  
Extensive Literature ◽  
Traditional Medicines ◽  
Digestive Disorder ◽  
Indigenous Groups ◽  
History Of

The genusTinosporaincludes 34 species, in which several herbs were used as traditional medicines by indigenous groups throughout the tropical and subtropical parts of Asia, Africa, and Australia. The extensive literature survey revealedTinosporaspecies to be a group of important medicinal plants used for the ethnomedical treatment of colds, headaches, pharyngitis, fever, diarrhea, oral ulcer, diabetes, digestive disorder, and rheumatoid arthritis. Indian ethnopharmacological data points to the therapeutic potential of theT.cordifoliafor the treatment of diabetic conditions. WhileTinosporaspecies are confusing in individual ingredients and their mechanisms of action, the ethnopharmacological history of those plants indicated that they exhibit antidiabetic, antioxidation, antitumor, anti-inflammation, antimicrobial, antiosteoporosis, and immunostimulation activities. While the clinical applications in modern medicine are lacking convincing evidence and support, this review is aimed at summarizing the current knowledge of the traditional uses, phytochemistry, biological activities, and toxicities of the genusTinosporato reveal its therapeutic potentials and gaps, offering opportunities for future researches.

scholarly journals HISTORY OF INDIAN TRADITIONAL MEDICINE: A MEDICAL INHERITANCE.

2018 ◽  
Vol 11 (1) ◽  
pp. 421 ◽  
Author(s):  
Partha Pradip Adhikari ◽  
Satya Bhusan Paul
Keyword(s):  
Traditional Medicine ◽  
Web Search ◽  
Care Service ◽  
Health Care Service ◽  
Modern Medicine ◽  
Traditional Medicines ◽  
Regional Effects ◽  
Practice Of Medicine ◽  
History Of ◽  
Traditional Approaches

 Objective: Indian Traditional Medicine, the foundation of age-old practice of medicine in the world, has played an essential role in human health care service and welfare from its inception. Likewise, all traditional medicines are of its own regional effects and dominant in the West Asian nations; India, Pakistan, Tibet, and so forth, East Asian nations; China, Korea, Japan, Vietnam, and so forth, Africa, South and Central America. This article is an attempt to illuminate Indian traditional medical service and its importance, based on recent methodical reviews.Methods: Web search engines for example; Google, Science Direct and Google Scholar were employed for reviews as well as for meta-analysis.Results: There is a long running debate between individuals, who utilize Indian Traditional Medicines for different ailments and disorders, and the individuals who depend on the present day; modern medicine for cure. The civil argument between modern medicine and traditional medicines comes down to a basic truth; each person, regardless of education or sickness, ought to be educated about the actualities concerning their illness and the associated side effects of medicines. Therapeutic knowledge of Indian traditional medicine has propelled various traditional approaches with similar or different theories and methodologies, which are of regional significance.Conclusion: To extend research exercises on Indian Traditional Medicine, in near future, and to explore the phytochemicals; the current review will help the investigators involved in traditional medicinal pursuit.

scholarly journals Plant-Based Drugs as an Adjuvant to Cancer Chemotherapy

2020 ◽  
Author(s):  
Lakshmi Mohan
Keyword(s):  
Natural Products ◽  
Cancer Chemotherapy ◽  
Herbal Medicines ◽  
Modern Medicine ◽  
Aquatic Life ◽  
Traditional Medicines ◽  
Synthetic Drugs ◽  
History Of ◽  
Drug Leads

Humans have turned to natural products, obtained from plants, animals and aquatic life for treating diseases since time immemorial. Modern medicine is based on ancient wisdom transferred over generations. Drug development relies mainly on natural sources. Herbal medicines are making a comeback due to lower side effects, and positive results in the long term when compared to synthetic drugs. The current drug discovery process relies on identifying traditional medicines followed by Bioactivity-guided fractionation to isolate significant lead molecules. Plants have a history of long-term use by humans and hence it can be presumed that the bioactive compounds obtained from plants will have low human toxicity. There exists a huge potential for discovering new antitumor drug leads by screening natural products either in the form of crude extracts purified phytochemicals which have already been described in the literature. The fact that phytochemicals like paclitaxel, vinblastine, vincristine and camptothecin are being successfully used in clinical practice and several others like combretastatin and noscapine are in different stages of clinical trials implies the importance of plants in cancer chemotherapy.

scholarly journals Quest for COVID-19 cure: integrating traditional herbal medicines in the modern drug paradigm

2020 ◽  
Vol 1 (1) ◽  
pp. 63-71
Author(s):  
Prativa Pandey ◽  
Angisha Basnet ◽  
Aatish Mali
Keyword(s):  
Drug Development ◽  
Traditional Medicine ◽  
Treatment Approach ◽  
Herbal Medicines ◽  
Economic Loss ◽  
Modern Medicine ◽  
Traditional Medicines ◽  
Modern Drug ◽  
History Of ◽  
Rich History

The world is facing one of the biggest public health tragedies of our time, both in terms of socio-economic loss and death tolls due to the coronavirus COVID-19 pandemic. In a frantic race to find treatment for COVID-19, many interventions to discover drugs and vaccines are being expedited. Similarly, traditional herbal medicines are also being explored to find a cure for COVID-19. There are many traditional medicines that have exhibited promising antiviral and immuno-modulating properties against a plethora of infectious diseases like influenza, malaria, tuberculosis, and even COVID-19. Traditional medicine is an integral part of culture and practices in many countries with a vast and rich history of treating diseases. However, scientific research-based drug development approaches and effective regulatory mechanisms, on par with modern medicine, should be implemented to ensure safety, efficacy and overall validity of traditional medicine. Incorporating evidence-based traditional medicines in modern drug development paradigms can help assure affordability, accessibility and acceptability of the treatment approach. Furthermore, it can create pharmacological synergism to tackle drug resistance. Altogether, every country should create a roadmap for modernization and revival of traditional knowledge to improve the health care system and be better prepared for health crises.

Level of use and public awareness in consumption of traditional medicines in work area of Health Center Gombong I

2020 ◽  
Vol 1 (3) ◽  
pp. 26-31
Author(s):  
Naelaz Zukhruf Wakhidatul Kiromah ◽  
Tri Cahyani Widiastuti
Keyword(s):  
Traditional Medicine ◽  
Urban Communities ◽  
Health Center ◽  
Public Awareness ◽  
Modern Medicine ◽  
Traditional Medicines ◽  
Rural And Urban ◽  
Work Area ◽  
Level Of Use ◽  
Minor Ailments

Indonesia has 20,000 types of plants where 300 species have been used as traditional medicines. The use of traditional medicine as an alternative treatment in Indonesia that has been used by both rural and urban communities. The use of traditional medicine is considered safer than modern medicine. The purpose of this study was to identify the level of use of traditional medicine and public awareness in the use of traditional medicine in work area of  Health Center Gombong 1 which consists of 5 villages. This research is a non-experimental and descriptive research that uses a questionnaire. Respondents who participated in this study were 140 people. The characteristics of respondents who participated in this study were the majority of men (50,71%), last educated of elementary school (41,43%), as housewives (27,86%). The majority of people in work area of Health Center Gombong choose treatment with modern medicine (64,29%). In addition there are 35,71% using traditional medicine and the majority use rhizome species (46%) for the treatment of minor ailments. In this study also showed that the majority of people do not know the safety of traditional medicines (50%) due to lack of information so that information is needed on the benefits and safety and the use of good and appropriate traditional medicines.

Characterization of Biologically Active Substances from Calendula officinalis

2018 ◽  
Vol 18 (14) ◽  
pp. 1167-1174 ◽  
Author(s):  
Petra Lovecka ◽  
Jan Lipov ◽  
Kamila Thumova ◽  
Anna Macurkova
Keyword(s):  
Biologically Active Substances ◽  
Biologically Active ◽  
Calendula Officinalis ◽  
Active Substances

The Booker Prize and Post-Imperial British Literature

2021 ◽  
Author(s):  
Chris Holmes
Keyword(s):  
United Kingdom ◽  
British Literature ◽  
Economic Value ◽  
Anglophone Literature ◽  
The United Kingdom ◽  
History Of ◽  
English Speaking ◽  
Commonwealth Of Nations ◽  
English Speaking World ◽  
British Colonies

In the particular and peculiar case of the Booker Prize, regarded as the most prestigious literary award in the United Kingdom (as measured by economic value to the author and publisher, and total audience for the awards announcement), the cultural and economic valences of literary prizes collide with the imperial history of Britain, and its after-empire relationships to its former colonies. From its beginnings, the Booker prize has never been simply a British prize for writers in the United Kingdom. The Booker’s reach into the Commonwealth of Nations, a loose cultural and economic alliance of the United Kingdom and former British colonies, challenges the very constitution of the category of post-imperial British literature. With a history of winners from India, South Africa, New Zealand, and Nigeria, among many other former British colonies, the Booker presents itself as a value arbitrating mechanism for a majority of the English-speaking world. Indeed, the Booker has maintained a reputation for bringing writers from postcolonial nations to the attention of a British audience increasingly hungry for a global, cosmopolitan literature, especially one easily available via the lingua franca of English. Whether and how the prize winners avoid the twin colonial pitfalls of ownership by and debt to an English patron is the subject of a great deal of criticism on the Booker, and to understand the prize as a gatekeeper and tastemaker for the loose, baggy canon of British or even global Anglophone literature, there must be a reckoning with the history of the prize, its multiplication into several prizes under one umbrella category, and the form and substance of the novels that have taken the prize since 1969.

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