PERBEDAAN TINGKAT KONSUMSI DAN KADAR KOLESTEROL DARAH ANTARA PEROKOK DAN NON PEROKOK

Cigarette smoke contains nicotine which disturbs health. Nicotine is capable of reducing the taste of food, so there is appetite suppressant. The ability of nicotine in increasing blood liposuction process can affect the increase in blood cholesterol level. The research aims to study the difference between food intake and blood cholesterol level between smokers and non-smokers. This study was a comparative observational analytic study using cross-sectional design. The data of particular subjects and smoking habit were obtained from the questionnaire. The food intake was obtained by interview using 2x24 hours food recall form while the blood cholesterol level was obtained by blood sampling which was then analyzed using laboratory test. The subjects were 13 smokers and 13 non-smokers, taken by simple random sampling. The data were analyzed by Independent t-Test. The results have suggested that the difference in the average food intake and blood cholesterol level between smokers and non-smokers were not significant. The substantial average difference was found in the level of cholesterol intake, so the statistical test has showed a significant difference, p-value = 0.005 < α(0.05). Smoking has a harmful effect for health so people must decrease its consumption or stay abstinent from it. The longer human get exposed to cigarette, the more susceptible they get the illness from it.

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The Relation of Fiber Intake, Cholesterol, and Physical Activity with Blood Cholesterol Level of Women Adult in Bogor Aerobic Studio

Nutri-Sains Jurnal Gizi Pangan dan Aplikasinya ◽

10.21580/ns.2018.2.2.2604 ◽

2018 ◽

Vol 2 (2) ◽

pp. 1

Author(s):

Adinda Maharani ◽

Avliya Quratul Marjan ◽

Luh Desi Puspareni

Keyword(s):

Physical Activity ◽

Cholesterol Level ◽

Cross Sectional Study ◽

Blood Cholesterol ◽

P Value ◽

Adult Women ◽

Blood Cholesterol Level ◽

Fiber Intake ◽

Cross Sectional ◽

Eating Pattern

<p>This study aims to analyze the relation between fiber intake, cholesterol, nutritional status, and physical activity with blood cholesterol level on adult women. The study design was a cross sectional study. The study involved 60 adult women (aged 40-64 y.o) in the Sanggar Senam Bugar Sehat Bogor as respondent. The analysis used was Chi-square test to assess the relation between variables. The result showed a signinificant relation of physical activity (p value=0,027, OR=0,098 ; 95% CI=0,012-0,809), fiber intake (p value=0,046, OR=7,724 ; 95% CI=0,918-64,260), and cholesterol intake (p value=0,000, OR=16,00 ; 95% CI=3,398-75,345) with blood cholesterol level. It is concluded that blood cholesterol levels are influenced by eating pattern, physical activities, and routine medical check up.</p>

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Perbedaan Penggunaan Antikoagulan K2EDTA DAN K3EDTA Terhadap Hasil Pemeriksaan Indeks Eritrosit

Jurnal Laboratorium Khatulistiwa ◽

10.30602/jlk.v1i2.147 ◽

2018 ◽

Vol 1 (2) ◽

pp. 114

Author(s):

Wahdaniah Wahdaniah ◽

Sri Tumpuk

Keyword(s):

Screening Test ◽

Venous Blood ◽

The Body ◽

Ethylene Diamine ◽

P Value ◽

Cross Sectional ◽

Significant Difference ◽

Ethylene Diamine Tetra Acetate ◽

The Difference ◽

Index Value

Abstract: Routine blood examination is the earliest blood test or screening test to determine the diagnosis of an abnormality. Blood easily froze if it is outside the body and can be prevented by the addition of anticoagulants, one of which Ethylene Diamine Tetra Acetate (EDTA). Currently available vacuum tubes containing EDTA anticoagulants in the form of K2EDTA and K3EDTA. K3EDTA is usually a salt that has better stability than other EDTA salts because it shows a pH approaching a blood pH of about 6.4. The purpose of this research is to know the difference of erythrocyte index results include MCH, MCV and MCHC using K3EDTA anticoagulant with K2EDTA. This research is a cross sectional design. This study used venous blood samples mixed with K2EDTA anticoagulant and venous blood mixed with K3EDTA anticoagulants, each of 30 samples. Data were collected and analyzed using paired different test. Based on data analysis that has been done on MCH examination, p value <0,05 then there is a significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value. Then on the examination of MCV and MCHC obtained p value <0.05 then there is no significant difference between samples with K3EDTA anticoagulant with K2EDTA to erythrocyte index value.Abstrak: Pemeriksaan darah rutin merupakan pemeriksaan darah yang paling awal atau screening test untuk mengetahui diagnosis suatu kelainan. Darah mudah membeku jika berada diluar tubuh dan bisa dicegah dengan penambahan antikoagulan, salah satunya Ethylene Diamine Tetra Acetate (EDTA). Dewasa ini telah tersedia tabung vakum yang sudah berisi antikoagulan EDTA dalam bentuk K2EDTA dan K3EDTA. K3EDTA biasanya berupa garam yang mempunyai stabilitas yang lebih baik dari garam EDTA yang lain karena menunjukkan pH yang mendekati pH darah yaitu sekitar 6,4. Tujuan dari penelitian ini adalah untuk mengetahui perbedaan hasil indeks eritrosit meliputi MCH, MCV dan MCHC menggunakan antikoagulan K3EDTA dengan K2EDTA. Penelitian ini merupakan penelitian dengan desain cross sectional. Penelitian ini menggunakan sampel darah vena yang dicampur dengan antikoagulan K2EDTA dan darah vena yang dicampur dengan antikoagulan K3EDTA, masing-masing sebanyak 30 sampel. Data dikumpulkan dan dianalisis menggunakan uji beda berpasangan. Berdasarkan analisis data yang telah dilakukan pada pemeriksaan MCH didapatkan nilai p < 0,05 maka ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit. Kemudian pada pemeriksaan MCV dan MCHC didapatkan nilai p < 0,05 maka tidak ada perbedaan yang signifikan antara sampel dengan antikoagulan K3EDTA dengan K2EDTA terhadap nilai indeks eritrosit.

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FC 068QUALITY OF LIFE OVER TIME IN OLDER MEN AND WOMEN WITH ADVANCED CKD - RESULTS FROM THE EQUAL STUDY

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfab122.002 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

Nicholas Chesnaye ◽

Yvette Meuleman ◽

Esther De Rooij ◽

Friedo W Dekker ◽

Marie Evans ◽

...

Keyword(s):

Harmful Effect ◽

Patient Characteristics ◽

P Value ◽

Joint Models ◽

Cross Sectional ◽

Linear Interaction ◽

Men And Women ◽

Negative Effect ◽

The Difference ◽

Over Time

Abstract Background and Aims Differences between the sexes are apparent in the epidemiology of CKD. Cross-sectional studies show that women consistently report a poorer health-related quality of life (QoL) than men, however, longitudinal studies are lacking. Here we investigate the sex-specific evolution of QoL over time in advanced CKD. As a secondary aim, we explore the sex-specific determinants of QoL. Method EQUAL is an observational prospective cohort study in stages 4 and 5 CKD patients ≥65 years not on dialysis with an incident estimated glomerular filtration rate (eGFR) < 20 ml/min/1.73m². Data on QoL (measured using the RAND-36), clinical and demographic patient characteristics were collected between April 2012 and September 2020. QoL trajectories were modelled by sex using linear mixed models, and joint models were applied to deal with informative censoring. We followed patients until death or dialysis initiation. Results We included 5151 QoL measurements in 1416 patients over a total of 1986 person years of follow-up. Overall, the physical component summary (PCS) declined with 2.0 (95% CI 1.4-2.6) points and the mental component summary (MCS) by 2.4 (95% CI 1.8-3.0) points per year. Although women had overall lower QoL scores, figure 1 demonstrates that PCS and MCS declined more than twice as fast in men (PCS: 2.4 per year, 95% CI 1.7 – 3.1, MCS: 2.9 per year, 95% CI 2.2 – 3.6) compared with women (PCS: 1.1 per year, 95% CI -0.2 – 2.0, MCS: 1.5 per year, 95% CI 0.5 – 2.4). We identified a non-linear interaction effect between sex and eGFR levels on QoL, demonstrating a stronger negative effect of decreased eGFR on both PCS (p=0.02) and MCS (p=0.04) in men compared with women. Subsequent adjustment for renal decline attenuated the difference in rate of QoL decline between men and women (difference after adjustment; PCS: 1.1, 95% CI -0.1 – 2.2, MCS: 1.2, 95% 0.0 – 2.3). In univariable analyses, higher serum haemoglobin was more beneficial to QoL in men compared to women (p-value for interaction; PCS: p=0.03, MCS: p=0.01). Higher serum phosphate had a strong harmful effect on both PCS and MCS in men, but not in women (PCS & MCS: p<0.001). The presence of pre-existing diabetes had a negative effect on PCS and MCS in men, but to a lesser extent in women (PCS: p=0.02, MCS: p=0.01). Conclusion Despite the higher overall QoL reported by men, both their physical and mental QoL declined approximately twice as fast compared with women. The faster decline in men was mediated in part by their lower levels of renal function, which had a stronger impact on their QoL as compared with women. Furthermore, in exploratory analyses we identified that high levels of phosphate, low levels of haemoglobin, and pre-existing diabetes were more detrimental to QoL in men than in women.

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Perbedaan kadar hemoglobin pada remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai

e-CliniC ◽

10.35790/ecl.4.1.2016.11696 ◽

2016 ◽

Vol 4 (1) ◽

Author(s):

Marianne C. Jacobus ◽

Max F.J Mantik ◽

Adrian . Umboh

Keyword(s):

Analytical Study ◽

Nutrition Status ◽

P Value ◽

Cross Sectional ◽

Significant Difference ◽

Good Nutrition ◽

The Difference ◽

Cross Sectional Design ◽

And Gender ◽

Main Component

Abstract: Haemoglobin is the main component of red blood cells that serves as a transporter of oxygen and carbon dioxide in the blood. The normal range of haemoglobin values can be used to determine the degree of anemia according to age and gender. Geographical condition such as altitude influences the haemoglobin value. This study aimed to obtain the difference of haemoglobin levels between teenagers with good nutrition status who live at the highland and those at the seaside. This was an observational analytical study with a cross sectional design. Samples were students with good nutrition status of SMPN 3 Tomohon (living at the highland) and those of SMP Kristen Nazaret Tuminting (living at the seaside). There were 60 students who met the inclusion criteria as follows: adolescent, good nutrition status, healthy, aged 13-15 years, lived at the highland or at the seaside ≥ 6 month, and willing to be performed blood examinations, and had been approved by their parents. The Mann-Whitney test for the difference between haemoglobin levels of the two groups showed a p value < 0,001. Conclusion: There was a very significant difference between haemoglobin levels of good nutrition teenagers who lived at the highland and at the seaside. Keywords: haemoglobin levels, good nutrition, teenagers, highland, seaside Abstrak: Hemoglobin merupakan komponen utama sel darah merah dan berfungsi sebagai transporter oksigen dan karbon dioksida dalam darah. Batas normal nilai hemoglobin dapat digunakan untuk menetapkan derajat anemia, dengan distribusi usia dan jenis kelamin spesifik didasarkan pada sampel referensi sehat. Kondisi geografis, seperti ketinggian tempat dari permukaan laut menjadi faktor pertimbangan dalam distribusi nilai normal hemoglobin. Penelitian ini bertujuan untuk mendapatkan perbedaan kadar hemoglobin antara remaja gizi baik yang tinggal di pegunungan dengan yang tinggal di tepi pantai. Jenis penelitian ini analitik-observasional dengan desain potong lintang. Sampel penelitian yaitu remaja gizi baik yang tinggal di pegunungan yaitu siswa SMPN 3 Tomohon dan yang di tepi pantai yaitu siswa SMP Kristen Nazaret Tuminting. Subjek penelitian berjumlah 60 remaja yang memenuhi kriteria inklusi yaitu gizi baik, sehat, berumur 13-15 tahun, berdomisili di pegunungan atau tepi pantai ≥6 bulan, bersedia dilakukan pemeriksaan darah, dan telah disetujui oleh orang tua. Data yang diperoleh dianalisis menggunakan uji Mann-Whitney dengan bantuan program SPSS. Hasil uji Mann-Whitney mengenai perbedaan kadar hemoglobin antara kedua kelompok menunjukkan nila p <0,001. Simpulan: Terdapat perbedaan yang sangat bermakna kadar hemoglobin remaja gizi baik yang tinggal di pegunungan dengan di tepi pantai.Kata kunci: kadar hemoglobin, remaja gizi baik, pegunungan, tepi pantai

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Migraine in Obesity: Is It Prevalent?

Diyala Journal of Medicine ◽

10.26505/djm.19025121223 ◽

2020 ◽

Vol 19 (2) ◽

pp. 1-5

Author(s):

Aso Sabir Saeed ◽

◽

Osama MohammadAmin Shukr

Keyword(s):

Body Mass Index ◽

Waist Circumference ◽

P Value ◽

Cross Sectional ◽

Waist To Hip Ratio ◽

Migraine Prevalence ◽

Significant Difference ◽

Keywords Migraine ◽

The Difference ◽

The Relationship

Background: Several studies have demonstrated an association between obesity and migraine. It’s still unclear whether migraine is the cause or it's the result of obesity. Objective: We investigated the prevalence of migraine among obese and non-obese individuals and analyzed the relationship between migraine prevalence and obesity. Patients and Methods: This is cross-sectional observational study was carried out at the neurology outpatients’ department of the Rizgary Teaching Hospital in Erbil, Iraq, from July 1st , 2018 to September 30, 2019. We interviewed and examined 300 persons, both obese (n=154) and non-obese (n=146), and of both gender. All of them were adults (>18 years old). Each person's weight, height, body mass index (BMI), and waist circumference were measured.The diagnosis of migraine was made according to the International Headache Society’s criteria. Obesity was present if the individual’s BMI is ≥30 and/or waist-to-hip ratio is >0.9 in females and >1.0 in males. Results: Out of the 300 persons, 14 males (8.5%) got migraines while migraine was found in 37 females (27.4%), irrespective of their weight. Out of the 300 persons, the prevalence of migraine among obese individuals was 21.4% (n=33) and while in non-obese individuals was 12.3% (n=18). There was a statistically significant difference between the groups (p-value=0.045). The overall prevalence of migraine was 16.9% of the persons interviewed. Conclusion: The results showed that migraine is more prevalent among obese persons than non-obese persons and the difference was statistically significant. Keywords: Migraine, obesity, BMI, headache

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Perbedaan Penyembuhan Luka Pasca Ekstraksi Gigi Antara Pasien Perokok Dengan Bukan Perokok Di RSGM Unsrat

e-GIGI ◽

10.35790/eg.7.2.2019.25141 ◽

2019 ◽

Vol 7 (2) ◽

Author(s):

Lidia A. Kewo ◽

Damajanty H.C. Pangemanan ◽

Aurelia Supit

Keyword(s):

Wound Healing ◽

Tooth Extraction ◽

Soft Tissues ◽

P Value ◽

Eligibility Criteria ◽

Cross Sectional ◽

Inflammatory Phase ◽

Significant Difference ◽

The Difference ◽

Cross Sectional Design

Abstract: To date, there are lots of documentations about the adverse effects of smoking on the oral cavity. Albeit, smoking is still considered as a casual thing in our community. Chemicals contained in the cigarette smoke can irritate the gums and soft tissues of the mouth, thus inhibiting wound healing after tooth extraction. This study was aimed to determine the difference in post-extraction dental wound healing between smokers and non-smokers. This was a comparative analytical study with a cross sectional design. Samples were obtained by using total sampling method. Subjects consisted of 16 smokers and 16 non-smokers that fulfilled the study eligibility criteria. Their oral cavities were examined to check the signs of inflammation (calor, dolor, rubor, tumor, and functio laesa). The results showed that there was a difference in post-extraction wound healing in inflammatory phase between smokers and non-smokers. As many as 9.4% of smoker patients and 34.4% of non-smoker patients recovered at 7 days post extraction. The Mann Whitney U test showed a p-value of 0.005. In conclusion, there was a significant difference in post-extraction wound healing between smokers and non-smokers.Keywords: smokers, non-smokers tooth extraction, wound healing Abstrak: Kebiasaan merokok bukan merupakan hal asing di masyarakat walaupun banyak dokumentasi mengenai akibat buruk dari merokok terhadap rongga mulut. Bahan kimia yang terdapat dalam asap rokok dapat mengiritasi gusi dan jaringan lunak mulut sehingga menghambat penyembuhan luka pasca ekstraksi gigi. Penelitian ini bertujuan untuk mengetahui perbedaan penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan bukan perokok. Jenis penelitian ialah analitik komparatif dengan desain potong lintang. Pengambilan sampel menggunakan total sampling yang memenuhi kriteria penelitian. Terdapat sebanyak 16 orang perokok dan 16 orang bukan perokok sebagai subyek penelitian. Pemeriksaan rongga mulut dilakukan untuk melihat tanda-tanda inflamasi (kalor, dolor, rubor, tumor, dan fungsio laesa). Hasil penelitian menunjukkan terdapat perbedaan penyembuhan luka 7 hari pasca ekstraksi gigi pada fase inflamasi antara pasien perokok dengan yang bukan perokok; sebanyak 9,4% pasien perokok dan 34,4% pasien bukan perokok yang sudah sembuh. Hasil uji Mann Whitney U mendapatkan nilai p=0,005. Simpulan penelitian ini ialah terdapat perbedaan bermakna dalam penyembuhan luka pasca ekstraksi gigi antara pasien perokok dengan yang bukan perokokKata kunci: perokok, bukan perokok, ekstraksi gigi, penyembuhan luka

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Comparison of Axial Ocular Measurements with Contact and Non-contact Biometry

Pakistan Journal of Ophthalmology ◽

10.36351/pjo.v36i1.922 ◽

2020 ◽

Vol 36 (1) ◽

Author(s):

Muhammad Arslan Ashraf ◽

Muhammad Suhail Sarwar ◽

Muhammad Awais Afzal ◽

Imran Khalid ◽

Sehrish Shahid

Keyword(s):

Corneal Thickness ◽

Anterior Chamber Depth ◽

Cross Sectional Study ◽

P Value ◽

Cross Sectional ◽

Kappa Test ◽

Parametric Data ◽

Significant Difference ◽

The Difference ◽

Graphical Presentation

Purpose: To compare between non-contact and contact biometry for measurements of central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and axial length (AL). Study Design: Descriptive Cross Sectional Study. Place and Duration of Study: Mayo Hospital, Lahore from June 2018 to December 2018. Material and Methods: Eighty-four subjects, (168 non-pathological eyes) visiting the eye outpatients department were recruited by non-probability convenience sampling. Patients with high refractive errors and suffering from any ocular pathology were excluded from the study. CCT, ACD, LT and AL were measured with non-contact Biometer (HAAG Streit) followed by Contact Biometer (Ultrasound) after taking consent from the patient. Data was entered and analyzed by using SPSS-21 and Medcalc software. Normality of quantitative data was checked with Shapiro Wilk test. Independent sample t test was used for parametric variable and Mann Whitney-U test was used for non-parametric data. For the agreement between two techniques Cohen’s Kappa test used and Bland-Altman plot was drawn for graphical presentation. P-value equal or less than 0.05 was taken as significant. Results: Mean age of 84 subject (female: 45.24% and male: 54.76%) was 53.05 ± 13.56 years. The AL was significantly longer for the non-contact measurement with the difference of 0.53 ± 0.32 mm (p < 0.001). Contact pachymetry was significantly higher with the difference of 8.67 ± 20.83 µm (p = 0.046). ACD was significantly deeper for non-contact measurements with the difference of 0.51 ± 0.32 mm (p < 0.001). Contact ultrasound A-scan measured LT significantly thicker with the difference of 0.59 ± 0.56 mm (p < 0.001). Conclusion: There is significant difference of axial ocular measurements (CCT, ACD, LT and AL) between contact (ultrasound A-scan) and non-contact (HAAG Streit) biometry (p < 0.05).

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PENGARUH AIR REBUSAN DAUN MAMPELAS (Teteracera indica) TERHADAP KADAR KOLESTEROL DARAH MENCIT

Scripta Biologica ◽

10.20884/1.sb.2017.4.3.453 ◽

2017 ◽

Vol 4 (3) ◽

pp. 197

Author(s):

Dian Samitra ◽

Zico Fakhrur Rozi

Keyword(s):

Cholesterol Level ◽

Blood Cholesterol ◽

Blood Cholesterol Level ◽

Cholesterol Levels ◽

Traditional Remedies ◽

Lower Blood Cholesterol ◽

Lower Blood ◽

Post Test ◽

The Mean ◽

The Difference

Tetracera indica Merr. locally known as Mampelas is commonly used in traditional remedies. It believed to have the potential to cure hypercholesterolemia. The potential use of this plant to lower blood cholesterol level was understudied; therefore this study aimed to determine the effect of the infusion of fresh leaves of Tetracera indica to the blood cholesterol levels of mice. This research was true experimental design, a post-test only design with nonequivalent (control) groups. This study used 25 male mice divided into five categories, i.e., P0 mice were administered with 0 g of infusion, P1 mice with 2 g infusion, P2 mice with 5 g infusion, P3 mice with 10 g infusion, and P4 mice without Tetracera indica infusion but 10 mg of simvastatin. The treatment in all categories were given continuously for seven days. The results showed the mean of the blood cholesterol levels were 169.4 ± 59.37 mg/dL in P0, 121.8 ± 7.62 mg/dL in P1, 136.2 ± 15.69 mg/dL in P2, 110.6 ± 37 , 01 mg/dL in P3 , and 179,0 ± 35,24 mg/dL in P4. Kruskal Wallis test was calculated to determine the difference of blood cholesterol level among all groups, and it reported p < 0.05. The results of this study showed that infusion of Tetracera indica leaf was significantly lowered the level of blood cholesterol in mice.

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PERBEDAAN TINGKAT KECEMASAN IBU BERSALIN DI PUSKESMAS DENGAN DI BIDAN PRAKTIK MANDIRI

Jurnal Akademika Baiturrahim Jambi ◽

10.36565/jab.v7i1.69 ◽

2018 ◽

Vol 7 (1) ◽

pp. 85

Author(s):

Fatihatul Hayati

Keyword(s):

Public Health ◽

Health Center ◽

Average Score ◽

P Value ◽

Cross Sectional ◽

Natural Childbirth ◽

Public Health Center ◽

Significant Difference ◽

The Difference ◽

Cross Sectional Design

Maternal mortality rate is higher in assisted childbirth rather than that of natural childbirth. The unresolved anxiety can cause childbirth to last longer and lead to assisted childbirth. Childbirth environment at the hospital can increase maternal anxiety which results in disturbing uterine contraction so that action should be taken to speed up the delivery process. The aim of this study was to determine the difference in anxiety level between mothers who give birth at the Public Health Center and those who give birth at Private Midwife Center. The study was conducted by cross-sectional design on 74 mothers in labor. They were divided into two groups: those who give birth at Public Health Center and those who give birth at Private Midwife Center with consecutive sampling technique.Data were then analyzed by conducting Independent T test. The result showed that the first group had higher average score of anxiety than the second group with p value < 0.05.The study suggested that there was significant difference between giving birth at Public Health Center and giving birth of Private Midwife Center

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The Difference of Serum Gastrin-17 Level Based on Gastritis Severity and Helicobacter Pylori Infection

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.325 ◽

2019 ◽

Vol 7 (8) ◽

pp. 1266-1269

Author(s):

Dumawan Harris Parhusip ◽

Gontar Alamsyah Siregar ◽

Leonardo Basa Dairi

Keyword(s):

Serum Gastrin ◽

Demographic Data ◽

Cross Sectional Study ◽

Mucosal Inflammation ◽

P Value ◽

Cross Sectional ◽

Significant Difference ◽

Sydney System ◽

The Difference ◽

H Pylori

BACKGROUND: Gastritis was defined as the histological presence of gastric mucosal inflammation. One of the most common aetiology was H. pylori. Gastrin-17 was a hormone that was secreted by G cells. H. pylori infection induced increased in gastrin-17 in gastritis. Therefore, this study was to investigate the relationship of gastrin-17 with gastritis severity and H. pylori infection. AIM: To determine the difference in serum Gastrin-17 level based on gastritis severity and H. pylori infection. METHODS: A cross-sectional study enrolling 45 patients with gastritis was conducted in Haji Adam Malik General Hospital between April and July 2018. Endoscopy and biopsy examinations were performed to confirm the diagnosis of gastritis. Gastritis severity was assessed using the Updated Sydney System. The presence of H. pylori infection was detected by a Campylobacter-like organism (CLO) examination. Gastrin-17 level and demographic data were also gathered. The analysis was done using Mann Whitney and Kruskal-Wallis test. P-value of < 0.05 was considered statistically significant. RESULTS: Serum Gastrin-17 level was significantly different based on gastritis severity (P = 0.001 according to neutrophils infiltration and P = 0.023 according to degree of atrophy), H. pylori infection (P = 0.038), and combined gastritis severity and H. pylori infection (P < 0.001). Serum Gastrin-17 level was higher in subjects with severe neutrophils infiltration, without atrophy, and with H. pylori infection. CONCLUSION: There was a significant difference in serum Gastrin-17 level based on gastritis severity and H. pylori infection.

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