scholarly journals SARS-CoV-2: Jumping the Species Barrier, Lessons from SARS and MERS, Its Zoonotic Spillover, Transmission to Humans, Preventive and Control Measures and Recent Developments to Counter This Pandemic Virus

2020 ◽  
Author(s):  
Kuldeep Dhama ◽  
Shailesh Kumar Patel ◽  
Khan Sharun ◽  
Mamta Pathak ◽  
Ruchi Tiwari ◽  
...  
Keyword(s):  
Virus Disease ◽  
Control Strategies ◽  
Control Measures ◽  
World Health ◽  
Risk Category ◽  
Species Barrier ◽  
Human Interface ◽  
Pandemic Virus ◽  
Short Period ◽  
And Control

Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome - Coronavirus-2) of the family Coronaviridae, appeared in Wuhan, Hubei province, China being its epicenter in December 2019. This disease was declared as posing Public Health International Emergency by World Health Organization on January 30, 2020, attained the status of a very high-risk category on February 29, and now having a pandemic status (March 11, 2020). COVID-19 has presently spread to more than 195 countries/territories while killing nearly 19,600 humans out of cumulative confirmed cases accounting to more than 430,000 within a short period of just a few weeks. The majority of deaths have been reported in Italy and China. Researchers worldwide are pacing with high efforts to counter the spread of this virus and to design effective vaccines and therapeutics/drugs. Few of the studies have shown the potential of animal-human interface and zoonotic links in the origin of SARS-CoV-2. Exploring the possible zoonosis and revealing the factors responsible for its initial transmission from animals to humans will pave ways to design and implement effective preventive and control strategies to counter COVID-19. The present review presents an overview of COVID-19 and the causative virus SARS-CoV-2, with particular emphasis on the role of animals and their jumping the cross-species barriers, experiences learned from SARS- and MERS-CoVs, zoonotic links, and spillover events, transmission to humans and rapid spread., highlighting in very brief the preventive and control measures along with a few of the recent research developments to counter this pandemic virus/disease.

scholarly journals Epidemic prevention and control measures in China significantly curbed the epidemic of COVID-19 and influenza

2020 ◽  
Author(s):  
Xiang-Sha Kong ◽  
Feng Liu ◽  
Hai-Bo Wang ◽  
Rui-Feng Yang ◽  
Dong-Bo Chen ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Prevention And Control ◽  
Virus Disease ◽  
Control Strategies ◽  
Mainland China ◽  
Control Measures ◽  
Spring Festival ◽  
Railway Passenger ◽  
Prevention And Control Measures ◽  
And Control

AbstractAt the end of 2019, an outbreak of unknown pathogen pneumonia occurred in China, then it was named corona virus disease 2019 (COVID-19). With the rapid spread of COVID-19, a series of strict prevention and control measures were implemented to cut the spread of the epidemic. Influenza as a respiratory tract infection disease as COVID-19 might also be controlled. To assess the effects, we used the total passenger numbers sent in mainland China from 2018 to 2020 and the daily number of railway passenger (DNRP) flow in 2020 during Spring Festival travel rush to reflect the population movement and further to analyze newly and cumulative confirmed COVID-19 and influenza. We found that with implementing the series measures on COVID-19, not only COVID-19, but also influenza mitigated in China. The prevention and control measures for COVID-19 might be used in controlling respiratory tract diseases, and reducing the national health economic burden. When other countries issue measures on COVID-19 and influenza, they should consider adopting more aggressive epidemic prevention and control strategies.

scholarly journals A mathematical model for the spread of COVID-19 and control mechanisms in Saudi Arabia

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Mostafa Bachar ◽  
Mohamed A. Khamsi ◽  
Messaoud Bounkhel
Keyword(s):  
Mathematical Model ◽  
Saudi Arabia ◽  
Virus Disease ◽  
Total Duration ◽  
Epidemiological Data ◽  
Control Measures ◽  
Control Mechanisms ◽  
Short Period ◽  
The One ◽  
And Control

AbstractIn this work, we develop and analyze a nonautonomous mathematical model for the spread of the new corona-virus disease (COVID-19) in Saudi Arabia. The model includes eight time-dependent compartments: the dynamics of low-risk $S_{L}$ S L and high-risk $S_{M}$ S M susceptible individuals; the compartment of exposed individuals E; the compartment of infected individuals (divided into two compartments, namely those of infected undiagnosed individuals $I_{U}$ I U and the one consisting of infected diagnosed individuals $I_{D}$ I D ); the compartment of recovered undiagnosed individuals $R_{U}$ R U , that of recovered diagnosed $R_{D}$ R D individuals, and the compartment of extinct Ex individuals. We investigate the persistence and the local stability including the reproduction number of the model, taking into account the control measures imposed by the authorities. We perform a parameter estimation over a short period of the total duration of the pandemic based on the COVID-19 epidemiological data, including the number of infected, recovered, and extinct individuals, in different time episodes of the COVID-19 spread.

scholarly journals Consequences of Mutations in Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2) Genome in Comparison to Other Pathogenic Coronaviruses

2021 ◽  
Vol 2 (2) ◽  
pp. 119-123
Author(s):  
Yusuf Amuda Agabi ◽  
Ismaila Shittu ◽  
Kennedy Iliya Amagon ◽  
James Garba Damen ◽  
Richard Joseph Kutshik ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Current Knowledge ◽  
Control Strategies ◽  
Control Measures ◽  
World Health ◽  
Diagnostics And Control ◽  
Wuhan City ◽  
Seasonal Flu ◽  
Health Organization ◽  
And Control

Background: Late December 2019, an unknown incidence of Pneumonia was observed among some residents of Wuhan city, China. The disease named coronavirus disease 2019 (COVID-19) and declared as a pandemic by the WHO on the March 11th, 2020 by the World Health Organization (WHO) has resulted to the death of million people across the globe. Prior to the current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), two other outbreaks of coronaviruses namely severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have been experienced within the last few decades. This review looks at the unique characteristics of SARS-CoV-2 to the other coronaviruses (SARS-CoV and MERS-CoV) and its significance(s) in the control strategies including diagnostics. Materials and Methods: Using the keywords “coronavirus mutation”, “nucleotide substitution”, “coronavirus evolution”, “SARS-CoV-2”, “COVID-19” published literatures on coronaviruses and SARS-CoV-2 were retrieved from MEDLINE and reviewed for gaps and current knowledge as it relates to evolution of SARS-CoV-2. Results: In comparison with seasonal flu, investigations revealed that SARS-CoV-2 mutates less rapidly which provides an edge in the possible development of a long-lasting vaccine to combat the spread of the virus. Though, several mutations in the genome of the virus with dire consequences on the diagnostics have been identified. Conclusions: The unique importance of mutation as a mechanism of survival for viruses cannot be overemphasized. Several mutations have been observed in SARS-CoV-2 genome whose implications as regards diagnostics and control measures have been highlighted herein.

scholarly journals Heterogeneity and effectiveness analysis of COVID-19 prevention and control in major cities in China through time-varying reproduction number estimation

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Qing Cheng ◽  
Zeyi Liu ◽  
Guangquan Cheng ◽  
Jincai Huang
Keyword(s):  
Prevention And Control ◽  
Large Scale ◽  
Reproduction Number ◽  
Correlation Method ◽  
Control Measures ◽  
Time Varying ◽  
Short Period ◽  
Significant Difference ◽  
Prevention And Control Measures ◽  
And Control

AbstractBeginning on December 31, 2019, the large-scale novel coronavirus disease 2019 (COVID-19) emerged in China. Tracking and analysing the heterogeneity and effectiveness of cities’ prevention and control of the COVID-19 epidemic is essential to design and adjust epidemic prevention and control measures. The number of newly confirmed cases in 25 of China’s most-affected cities for the COVID-19 epidemic from January 11 to February 10 was collected. The heterogeneity and effectiveness of these 25 cities’ prevention and control measures for COVID-19 were analysed by using an estimated time-varying reproduction number method and a serial correlation method. The results showed that the effective reproduction number (R) in 25 cities showed a downward trend overall, but there was a significant difference in the R change trends among cities, indicating that there was heterogeneity in the spread and control of COVID-19 in cities. Moreover, the COVID-19 control in 21 of 25 cities was effective, and the risk of infection decreased because their R had dropped below 1 by February 10, 2020. In contrast, the cities of Wuhan, Tianmen, Ezhou and Enshi still had difficulty effectively controlling the COVID-19 epidemic in a short period of time because their R was greater than 1.

scholarly journals Developing a theory-based behavior change intervention to improve the prescription of surgical prophylaxis in an Egyptian University Hospital.

2021 ◽  
Author(s):  
Anna-Leena Lohiniva ◽  
Iman Heweidy ◽  
Samiha Abdu ◽  
Abouelata Omar ◽  
Caroline Ackley ◽  
...  
Keyword(s):  
Behaviour Change ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Theoretical Domains Framework ◽  
Control Measures ◽  
World Health ◽  
Infection Prevention And Control ◽  
Surgical Prophylaxis ◽  
Context Specific ◽  
And Control

Abstract Background: Antimicrobial resistance (AMR) is increasingly pervasive due to multiple, complex prescribing and consuming behaviours. Accordingly, behaviour change is an important component of response to AMR. Little is known about the best approaches to change antibiotic use practices and behaviours. This project aims to develop a context-specific behaviour change strategy focusing on promoting appropriate prescription practices following the World Health Organization recommendations for surgical prophylaxis in an orthopaedic surgery unit in Egypt.Methods: The project included a formative qualitative research study was based on the Theoretical Domains Framework (TDF) to explore the determinants for inappropriate prescription of surgical antibiotic prophylaxis at an orthopaedic unit. The intervention was developed to following the Behaviour Change Wheel (BCW) in a knowledge co-production workshop with infection prevention and control experts that ensured that the theory based intervention was a culturally acceptable, practical and implementable intervention. Results: The prescription of surgical prophylaxis was influenced by five TDF domains including, knowledge, belief in consequences (mistrust towards infection prevention and control measures), environmental factors (lack of prescription guidelines) , professional role and reinforcement (a lack of appropriate follow up actions influenced prescription of surgical prophylaxis). The appropriate set of behaviour change functions of BCW and related activities to improve the current practices included education, enablement, persuasion, environmental restructuring and restriction. Conclusions The study showed that a theory based and context specific intervention can be created by using the TDF and BCW together with knowledge-co creation to improve the prescription of surgical prophylaxis in and Egyptian orthopaedic unit. The intervention need to piloted and scaled up.

The Study of the Beijing Traffic Noise Pollution Control Countermeasures

2014 ◽  
Vol 641-642 ◽  
pp. 853-859
Author(s):  
Wei Wang ◽  
Hui Zhao ◽  
Guan Xing Wang ◽  
Hua Zhen Zhou
Keyword(s):  
Road Traffic ◽  
Control Strategies ◽  
Traffic Noise ◽  
Noise Pollution ◽  
Environmental Issues ◽  
Control Measures ◽  
Road Traffic Noise ◽  
Typical Time ◽  
The Status ◽  
And Control

Traffic noise is a major source of noise pollution in the urban environment, including road traffic noise and rail traffic noise, which has become one of the domestic large and medium cities in environmental issues to be solved. This paper analyzes the status of the Beijing traffic noise pollution and control strategies, and a typical apartment block selected as a case, analyzes its noise pollution elements, severity, time distribution, and draws a noise map of the plane area and a dormitory building in the noise conditions typical time. Last we discussed and gave the method based on noise control measures.

scholarly journals Modeling the Impact of Optimal Control Strategies on the Dynamics of Zika Virus Disease Using the Sterile Insect Technology

2020 ◽  
pp. 13-33
Author(s):  
Atokolo William ◽  
Akpa Johnson ◽  
Daniel Musa Alih ◽  
Olayemi Kehinde Samuel ◽  
C. E. Mbah Godwin
Keyword(s):  
Optimal Control ◽  
Control Strategy ◽  
Zika Virus ◽  
Human Population ◽  
Necessary Conditions ◽  
Virus Disease ◽  
Control Strategies ◽  
Control Measures ◽  
Optimal Control Strategy ◽  
The Impact

This work is aimed at formulating a mathematical model for the control of zika virus infection using Sterile Insect Technology (SIT). The model is extended to incorporate optimal control strategy by introducing three control measures. The optimal control is aimed at minimizing the number of Exposed human, Infected human and the total number of Mosquitoes in a population and as such reducing contacts between mosquitoes and human, human to human and above all, eliminates the population of Mosquitoes. The Pontryagin’s maximum principle was used to obtain the necessary conditions, find the optimality system of our model and to obtain solution to the control problem. Numerical simulations result shows that; reduction in the number of Exposed human population, Infected human population and reduction in the entire population of Mosquito population is best achieved using the optimal control strategy.

scholarly journals Epidemiology of Bovine Mastitis and its Diagnosis, Prevention, and Control

2021 ◽  
Author(s):  
S.D. Audarya ◽  
D. Chhabra ◽  
R. Sharda ◽  
R. Gangil ◽  
R. Sikrodia ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Control Strategies ◽  
Significant Proportion ◽  
Bovine Mastitis ◽  
The State ◽  
Madhya Pradesh ◽  
Control Measures ◽  
Prevention And Control Measures ◽  
Etiological Agents ◽  
And Control

Mastitis is an inflammation of mammary glands that is prevalent in dairy bovines. It causes a significant proportion of economic losses to the dairy farmers in India. Cattle and buffalo farming contribute significantly to the economy of the state. Various infectious agents such as bacteria, fungi, and algae may cause mastitis. Hence, it is essential to understand the etiological agents and predisposing factors that lead to mastitis in susceptible bovine populations in Madhya Pradesh state so that appropriate prevention and control strategies can be implemented. In this chapter, epidemiology, diagnosis, prevention, and control measures of mastitis in general and in India, the state of Madhya Pradesh, in particular, will be presented.

scholarly journals Dengue and Recent Mosquito-borne Viral Fever Outbreak in Bangladesh: Concern, Causes and Control

2019 ◽  
pp. 44-48 ◽  
Keyword(s):  
Control Measures ◽  
World Health ◽  
Health Concern ◽  
The Past ◽  
Directorate General ◽  
Elevated Rate ◽  
Health Organization ◽  
And Control ◽  
Control Division ◽  
Great Public Health

Bangladesh is struggling with dreadful outbreaks of mosquito-borne diseases for the past few years. Disease Control Division of Directorate General (DG) of Health Service considered the capital of Bangladesh as the breeding ground for mosquitos. Recent incidence of Dengue and Chikungunya outbreaks have surpassed all past records of outbreak. Thus, the country is witnessing an elevated rate of viral fever incidence alarmingly. Though symptoms of mosquito-borne viral infection are very typical, the recent incidence of fatalities is growing great public health concern. World Health Organization (WHO) recommends practical control measures to minimize the breeding within the community of Bangladesh. The actions of Kolkata City Corporation to control Dengue are also suggestive for Bangladesh. There is no medication to treat Dengue, and Chikungunya infection, but initial recognition and apposite medical care can reduce the death threat.

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