scholarly journals Study the Oxidative Stress, Some Biochemical and Hematological Parameters in patients with agout at AL-Ramadi city

2016 ◽  
Vol 13 (4) ◽  
pp. 694-701
Author(s):  
Baghdad Science Journal
Keyword(s):  
Blood Cells ◽  
Hematological Parameters ◽  
Age Groups ◽  
Control Group ◽  
Enzymatic Antioxidants ◽  
Blood Picture ◽  
Control Groups ◽  
Blood Samples ◽  
Normal Individuals ◽  
And Control

This study aims to study the effect of gout disease on complete blood picture and biochemical parameters and some non-enzymatic antioxidants, some tracing elements and lipid peroxidation ,in outpatients with gout disease at Al-Ramadi Teaching-Hospital ,Al-Razi Hospital and the study duration from Octo.2013-to May 2014.(50) blood samples were collected from patients with age groups (30-80 years) from both sexes (28 males,22 females),a (30) blood samples (15 males,15 females) were collected from normal individuals as a control group with age groups (27-75 years). Hematological measurement showed no significant differences in size compressed blood cells, the percentages in ( 45.15 +4.99 and 46.87+6.30) % in patient and control groups respectively, hemoglobin concentrations were ( 14.04+1.66 and 14.30+1.93) g/l in patient and control groups respectively, total number of red blood cells ( 5.21+0.43 and 5.12 +0.58) 106/mm3 in patient and control groups respectively with(P?0.05) in ESR (21.06+13.47 and 13.37 +7.45) mm/hr in patient and control groups respectively with (P?0.05), the total number of WBCs were recorded (8.96+2.04 and 7.50+1.69)in patient and control groups respectively. Results showed also significant differences (P?0.05) in uric acid levels (7.42+0.76 and 5.62+0.88) mg/dl,malondialdehyde levels were recorded (4.45+0.64 and 3.21+0.86) in patient and control groups

scholarly journals DETERMINING THE ASSOCIATION BETWEEN DERMATOGLYPHICS AND SCHIZOPHRENIA BY USING FINGERPRINT ASYMMETRY MEASURES

2008 ◽  
Vol 22 (03) ◽  
pp. 601-616 ◽  
Author(s):  
JEN-FENG WANG ◽  
CHEN-LIANG LIN ◽  
CHEN-WEN YEN ◽  
YUNG-HSIEN CHANG ◽  
TENG-YI CHEN ◽  
...  
Keyword(s):  
Intervention Strategies ◽  
Control Group ◽  
Fingerprint Matching ◽  
Control Groups ◽  
Orientation Field ◽  
Indirect Measures ◽  
Normal Individuals ◽  
Schizophrenic Patients ◽  
Asymmetry Measures ◽  
And Control

Early detection and intervention strategies for schizophrenia are receiving increasingly more attention. Dermatoglyphic patterns, such as the degree of asymmetry of the fingerprints, have been hypothesized to be indirect measures for early abnormal developmental processes that can lead to later psychiatric disorders such as schizophrenia. However, previous results have been inconsistent in trying to establish the association between dermatoglyphics and schizophrenia. The goal of this work is to try to resolve this problem by borrowing well-developed techniques from the field of fingerprint matching. Two dermatoglyphic asymmetry measures are proposed that draw on the orientation field of homologous fingers. To test the capability of these measures, fingerprint images were acquired digitally from 40 schizophrenic patients and 51 normal individuals. Based on these images, no statistically significant association between conventional dermatoglyphic asymmetry measures and schizophrenia was found. In contrast, the sample means of the proposed measures consistently identified the patient group as having a higher degree of asymmetry than the control group. These results suggest that the proposed measures are promising for detecting the dermatoglyphic patterns that can differentiate the patient and control groups.

scholarly journals Evaluation of Gamavit effectiveness for correction of renal anemia in cats with chronic kidney disease: a controlled randomized study

2020 ◽  
Vol 2020 (5) ◽  
pp. 8-20
Author(s):  
Roman Leonard ◽  
Tat'yana Zaripova ◽  
Aleksandr Balahonov ◽  
Natal'ya Vdovina ◽  
Aleksandr Narovlyanskiy ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Renal Anemia ◽  
Control Group ◽  
Control Groups ◽  
Ckd Stage ◽  
Group A ◽  
And Control ◽  
Experimental Group ◽  
Stimulation Of

Renal anemia is one of the most common complications of chronic kidney disease (CKD) in cats, which significantly reduces their life quality. Most often, the mechanism of renal anemia development is associated with insufficiency of endogenous erythropoietin (EPO), or with a reduction in the life of red blood cells caused by uremic intoxication. Since anemia increases the severity of renal hypertension and other CKD symptoms, the search for effective drugs that can stimulate erythropoiesis in CKD and do not have nephrotoxic properties is particularly relevant. The aim of the work was to study the effectiveness of Gamavit in the treatment regimen for cats with CKD compared with the standard treatment protocol. Active ingredients of Gamavit are sodium nucleinate and denaturated placenta extract. The study included 20 cats of different breeds aged from 5 to 16 years with CKD stage III-IV according to the IRIS classification, accompanied by anemia and a decrease in hematocrit in the range from 25 to 16%. Patients were randomly divided into 2 equal groups - control (n=10) and experimental (n=10) using the block randomization method. In the control group a standard nephroprotective therapy regimen was used. In the experimental group Gamavit was added to the standard regimen. Gamavit was administered at a dose of 0.5 ml/kg 1 time per day, at the same time, during 14 consecutive days (7 days i/v and 7 days s/c). The conditions for feeding and keeping animals of the experimental and control groups were identical. For feeding, we used a standardized serial diet ― Purina CatChow Adult with chicken/turkey/salmon. Access to drinking water ― ad libitum. The initial number of red blood cells, as well as the hematocrit index and hemoglobin level in the experimental and control groups were at the lower limit of the norm or below the reference values. During the study, in the experimental group of the patients, these indicators returned to normal after 2 weeks, while in the control group there were no significant changes. The statistically significant difference between the experimental and control groups remained until the end of the observation (p=0.001). Levels of creatinine and urea in the blood serum of the patients of both groups consistently high throughout the study, but in the experimental group a significant decrease in these indicators was found. The initial level of EPO in both groups was significantly lower than in healthy cats. During the experiment, it was not possible to reach the lower limit of the normal value, which allows us to conclude that the stimulation of erythropoiesis indicators in the experimental group, observed under the influence of Gamavit, is not associated with the stimulation of endogenous EPO production. Thus, the study revealed that Gamavit stimulates erythropoiesis in cats with CKD stage III-IV, significantly increasing the number of red blood cells, and the levels of hematocrit and hemoglobin. This effect, combined with a decrease in uremic intoxication values (creatinine and urea levels), lead to an improvement in the general condition of patients and regression in a number of important clinical manifestations. Since no nephrotoxic effects and undesirable interactions with drugs of standard nephroprotective therapy were detected in the process of this study, Gamavit can be recommended for widespread use in cats as one of the pathogenetic, symptomatic, and therapeutic and prophylactic drugs in the complex therapy of CKD at the preclinical and clinical stages of the disease.

68 GROWTH, REPRODUCTION, AND LACTATION IN SOMATIC CELL-CLONED HOLSTEIN COWS AND THEIR PROGENY

2007 ◽  
Vol 19 (1) ◽  
pp. 151
Author(s):  
K. Nagano ◽  
J. Todoroki ◽  
M. Imamura ◽  
C. Kubota
Keyword(s):  
Blood Cells ◽  
Dry Matter ◽  
Dry Matter Intake ◽  
Holstein Cows ◽  
Control Group ◽  
Control Groups ◽  
Donor Cells ◽  
Blood Characteristics ◽  
And Control ◽  
Clone Group

We investigated the safety of somatic cell-cloned Holstein cows and the analogy (growth and milk performance) of the cloned cows and their progeny. Individually, the cloned cows were produced using the same fibroblasts of a Holstein cow as the donor cells. All cows were fed in accordance with NRC (1999) standards during the experimental period. Three cloned cows (clone group), their 3 progeny (progeny group), and 3 cows produced with artificial insemination (AI, control group) were reared under general group feeding. Viability, fertility, milk yield,and blood characteristics in clone, progeny, and control groups were examined. Statistical analyses were carried out by Student's t-test. The birth weight in the clone group (55.2 ± 6.3 kg (mean ± SD)) was heavier than that of the control group (44.8 ± 5.6 kg (P > 0.05)); it was also heavier than that of an upper limit (51.0 kg) and standard value (40.0 ± 5.8 kg) of Holstein heifers in Japan. However, no significant change in the amount of dry matter intake per kg body weight/day was observed between the clone group (0.97 ± 0.06 kg) and the control group (0.9 ± 0.02 kg). As to blood characteristics in the raising phase, the number of red blood cells in the clone group (684.8 ± 16.8 × 104 µL) was decreased slightly (P < 0.01) compared with that in the control group (823.3 ± 26.1 × 104 µL). However, there were no differences in other blood test items between clone and control groups. Furthermore, we found that there were no differences in estrous cycles and plasma progesterone concentrations between clone and control groups. All cloned and control cows that had been inseminated became pregnant and delivered normally. During the period from 21 days before expected date of confinement to 10 days after parturition, relative to the blood characteristics, the number of blood cells in the clone group (499.9 ± 77.5 × 104 µL) tended to be lower (P < 0.01), when compared to that in the control group (711.2 ± 39.9 × 104 µL); no differences were observed in plasma estrogen and progesterone concentrations between clone and control groups throughout the measurement period. In the first lactation period, there were no differences in total amount of milk produced in the first 305 days of lactation, milk percentage, milk protein rate, and solids-not-fat between clone and control groups. The total amount of milk produced in the first 365 days in cloned cows was almost equal to that of the original cow who provided donor cells. In 3 progeny of the cloned cows, the average birth weight was not different from that in the control group and the standard growth value. In the raising period, there were no differences in changes of the weight and height of a body and of the dry matter intake per day, and in the blood characteristics between progeny and control groups. Conceivably, our results suggest that the cloned Holstein cows and their progeny have normal growth, reproductive, and lactation characteristics, although the birth weights of the cloned cows were larger than those of control cows.

scholarly journals Power Doppler Ultrasound Evaluation of Peripheral Joint, Entheses, Tendon, and Bursa Abnormalities in Psoriatic Patients: A Clinical Study

2018 ◽  
Vol 45 (6) ◽  
pp. 811-817 ◽  
Author(s):  
Yuanjiao Tang ◽  
Yujia Yang ◽  
Xi Xiang ◽  
Liyun Wang ◽  
Lingyan Zhang ◽  
...  
Keyword(s):  
Middle Age ◽  
Power Doppler ◽  
Age Groups ◽  
Clinical Signs ◽  
Joint Effusion ◽  
Control Group ◽  
Power Doppler Ultrasound ◽  
Control Groups ◽  
Ultrasound Evaluation ◽  
And Control

Objective.To evaluate the prevalence rates of peripheral joint, enthesis, tendon, and bursa abnormalities by power Doppler (PD) ultrasonic examination in patients with psoriatic arthritis (PsA), psoriatic patients without clinical signs of arthritis (non-PsA psoriasis group), and healthy individuals, to detect subclinical PsA.Methods.A total of 253 healthy volunteers, 242 non-PsA psoriatic patients, and 86 patients with PsA were assessed by 2-dimensional and power Doppler (PD) ultrasound. Peripheral joint, enthesis, tendon, and bursa abnormalities were observed, characterizing abnormal PD. The affected patients and sites with abnormalities in various ages were compared among groups; PD signal grades for the abnormalities were also compared.Results.In the PsA group, significantly higher percentages of sites showing joint effusion/synovitis, enthesitis, and tenosynovitis in all age groups, and markedly higher rates of sites with bursitis were found in young and middle age groups, compared with the non-PsA and control groups (all p < 0.01). Meanwhile, the non-PsA group showed significantly higher rates of joint effusion/synovitis and enthesitis sites, and elevated PD signal grades of synovitis, enthesitis, and tenosynovitis in comparison with the control group, both in young and middle age groups (all p < 0.01).Conclusion.Patients with PsA have high percentages and PD signal grades of peripheral joint, tendon, enthesis, and bursa involvement. Young and middle-aged non-PsA patients have high synovitis and enthesitis percentages, and elevated PD signal grades of synovitis, enthesitis, and tenosynovitis.

scholarly journals Effect of Adiponectin Hormone on Serum Lipoproteins Levels in Female Rats

2013 ◽  
Vol 12 (2) ◽  
pp. 50
Author(s):  
H, A. A. Al-Baka`a
Keyword(s):  
Normal Saline ◽  
Treated Group ◽  
Female Rats ◽  
Control Group ◽  
Serum Lipoproteins ◽  
Control Groups ◽  
Dose Administration ◽  
Blood Samples ◽  
And Control

This investigation aimed to study the effect of adiponectin hormone on serum lipoproteins levels in female rats. For this purpose, thirteen female rats were divided into treated and control groups. Each animal in the treated group received a daily intraperitoneal 25microgram does of adiponectin dissolved in 0.2ml normal saline for fifteen respective days. In the same time, each animal in the control group received a daily intraperitoneal 0.2ml normal saline for fifteen respective days. The animal has fasted for 12 hours after last dose administration. Blood samples were collected, and the sera obtained. Analysis showed a significant increase in the serum HDL level and a significant decrease in LDL concentration. AP < 0.05was considered significant.

Evaluation of serum ischaemia-modified albumin levels in patients with Bell's palsy

2019 ◽  
Vol 133 (09) ◽  
pp. 810-813
Author(s):  
A E Göker ◽  
M H Alagöz ◽  
G Güntaş ◽  
A Baskadem Yilmazer ◽  
G Berkiten ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Bell’S Palsy ◽  
Control Group ◽  
Study Group ◽  
Healthy Individuals ◽  
Bell's Palsy ◽  
Control Groups ◽  
Blood Samples ◽  
And Control ◽  
The Relationship

AbstractObjectiveThis prospective study aimed to evaluate the relationship between serum ischaemia-modified albumin levels and Bell's palsy severity.MethodsThe study included 30 patients diagnosed with Bell's palsy and 30 healthy individuals. The patients were separated into three disease severity groups (grades 2, 3 and 4) according to House–Brackmann classification. Blood samples were collected from all participants and the results compared between groups.ResultsSignificant differences in serum ischaemia-modified albumin were found between the study and control groups (p &lt; 0.001); values were significantly higher in the study group than in the control group.ConclusionThe significantly higher levels of serum ischaemia-modified albumin in the study group suggest that Bell's palsy pathogenesis is associated with oxidative stress.

Astudy of some aspects of reproductive Performance in rabbits treated with Hydrocortisone

2001 ◽  
Vol 25 (1) ◽  
pp. 1-12
Author(s):  
J. K. Al- Ar rak
Keyword(s):  
Reproductive Performance ◽  
Physiological Saline ◽  
Testicular Tissue ◽  
Plasma Testosterone ◽  
Control Group ◽  
Functional Aspect ◽  
Control Groups ◽  
Blood Samples ◽  
Pretreatment Period ◽  
And Control

This experiment was carried out to study the changes in some of the structural – functional and biochemical aspects that are related to reproductive performance as a result of using glncocorticoid - hydrocortisone. Twelve adult male rabbit were divided into two equal groups : control and treatment. During pretreatment period ( Five days) blood samples were collected from all animals on every other days . During the treatment period (14) days each animal of the treatment group was injected daily , intramuscularly with hydrocortisone . Rabbit of the control group were injected with the same dose of normal physiological saline. Blood samples were collected as described above until (48) hours after last injection . All animals were scarified and samples from testicular tissue were taken to study structural – functional aspect.  Statistical analysis showed significant (P < 0.05) decrease in plasma testosterone of hydrocortisone treated rabbits, plasma levels of ICSH of both treatment and control groups of rabbits were parallel to each other (P< 0.05).

scholarly journals Seroprevalence of Toxoplasma gondii and associated hematological alterations in small ruminants of D.G. Khan district of Southern Punjab, Pakistan

2020 ◽  
Vol 72 (5) ◽  
pp. 1698-1704
Author(s):  
M.H. Lashari ◽  
U. Farooq ◽  
S. Mubeen ◽  
W. Hassan ◽  
M.F. Azhar ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Blood Cells ◽  
Hematological Parameters ◽  
Age Groups ◽  
Small Ruminants ◽  
Blood Samples ◽  
Elisa Kit ◽  
Hematological Effects ◽  
And Gender ◽  
Hematological Alterations

ABSTRACT The present study was carried out to evaluate the prevalence and hematological effects of Toxoplasma gondii in sheep and goat in district Dera Ghazi Khan. Blood samples (n=204) were collected comprise goats (n=101) and sheep (n=103) alongwith age, gender and breeds of animals. Samples were collected randomly from 25 flocks of 7 different union council Viz. Vehova, Tibbi Qaisrani, Lakhani, Kohar, Tuman Qaisrani, Nutkani and Kot Qaisrani of Tehsil Taunsa Sharif at least 4 animals from each flock. All ruminants divide into three groups based on age, breed and gender. The prevalence was detected through two different kits Viz. LAT and ELISA kit. The overall prevalence suspected in goats through LAT and ELISA kit was (35.64%), (32.67%) and in sheep was (25.24%), (23.30%) respectively. The Toxoplasma gondii had a significant effect on goats in age groups and non-significant all other groups of goats and sheep. Toxoplasma gondii had a significant effect on all hematological parameters like Hemoglobin, total leukocyte cells, granulocytes, lymphocytes, platelets, and red blood cells, except monocytes. In conclusion of the current study, toxoplasmosis is prevalent among ruminants, reveals the possibility of transmission to humans on the use of host animals as protein source.

Visual Reinforcement of Head-Turn Responses in Infants Under 12 Months of Age

1977 ◽  
Vol 42 (3) ◽  
pp. 328-334 ◽  
Author(s):  
John M. Moore ◽  
Wesley R. Wilson ◽  
Gary Thompson
Keyword(s):  
Age Groups ◽  
The Other ◽  
Auditory Signal ◽  
Control Group ◽  
Head Turn ◽  
Control Groups ◽  
Visual Reinforcement ◽  
Significant Difference ◽  
And Control ◽  
Experimental Group

The effect of complex visual reinforcement (animated toy animal) on auditory localization responses of infants below 12 months of age was studied. Sixty infants served as subjects and each subject received 30 presentations of complex noise at suprathreshold level. After each response to an auditory signal, one-half of the infants (experimental group) received complex visual reinforcement and the other half (control group) received no reinforcement. The experimental and control groups were further subdivided into three age groups: four months, five and six months, and seven to 11 months. Visual reinforcement produced significantly more responses (head turn) than no reinforcement for the two older age groups. There was no significant difference between the experimental and control conditions at four months of age.

Conjugated Linoleic Acid Causes a Marked Increase in Liver α-Tocopherol and Liver α-Tocopherol Transfer Protein in C57BL/6 J Mice

2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw
Keyword(s):  
Antioxidant Enzymes ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Thiobarbituric Acid ◽  
Control Group ◽  
Thiobarbituric Acid Reactive Substances ◽  
Control Groups ◽  
Protein Levels ◽  
Transfer Protein ◽  
And Control

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.

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