scholarly journals Assessment of Asymptomatic Bacteriuria and Sterile Pyuria among Antenatal Attendants in hospitals in Northern Ghana

2020 ◽  
Author(s):  
Akosua Bonsu Karikari ◽  
Courage Kosi Setsoafia Saba ◽  
David Yembilla Yamik

Abstract Background Asymptomatic bacteriuria (ASB) and sterile pyuria (SP) are complexities of UTI whose prevalence are not known in the northern sector of Ghana. Our aim was to determine the occurrence of sterile pyuria and asymptomatic bacteriuria among pregnant women accessing antenatal care at a secondary and tertiary care hospitals in Tamale, northern Ghana.Methods A cross sectional study was conducted by screening 530 pregnant women with no signs of acute urinary tract infection attending antenatal clinic for a period of 6 months. Midstream urine was collected for microscopy, quantitative urine culture and antibiotic susceptibility testing. Data analysis was carried out using the Statistical Package for Social Sciences version 20.Results Of the 390 and 90 women screened for ASB, prevalence was 20% and 35.5% respectively at Tamale Central and Tamale Teaching Hospital. Sterile pyuria was found among 66% of the 50 women presenting at Tamale Central Hospital. More than 64% of isolates recovered from ASB patients were S. aureus and coagulase negative Staph. ( CoNS ). Escherichia coli was the dominant species among members of the enterobacteriaceae isolated. Highest susceptibility was recorded against gentamicin and amikacin while most resistance was to Ampicillin, cotrimoxazole, chloramphenicol and nitrofurantoin. Resistance to imipenem and vancomycin were 28.8% and 52%, with strains showing multiple drug resistance of between 81-92%.Conclusion The prevalence of asymptomac bacteriuria is appreciably higher (20-35.5%) than documented rates in the southern sector of the country. The presence of sterile pyuria which may be an indication of asymptomatic renal impairment and most often overlooked in antenatal management is 66%. Empirical treatment of UTIs at the Tamale Central and Teaching Hospital without confirmation of susceptibility may result in treatment failure. It is necessary to screen and treat pregnant women for ASB and SP due to the complications associated with these conditions.

2019 ◽  
Author(s):  
Akosua Bonsu Karikari ◽  
Courage Kosi Setsoafia Saba ◽  
David Yembilla Yamik

Abstract Background Asymptomatic bacteriuria (ASB) and sterile pyuria (SP) are complexities of UTI whose prevalence are not known in the northern sector of Ghana. Our aim was to determine the occurrence of sterile pyuria and asymptomatic bacteriuria among pregnant women accessing antenatal care at a secondary and tertiary care hospitals in Tamale, northern Ghana.Methods A cross sectional study was conducted by screening 530 pregnant women with no signs of acute urinary tract infection attending antenatal clinic for a period of 6 months. Midstream urine was collected for microscopy, quantitative urine culture and antibiotic susceptibility testing. Data analysis was carried out using the Statistical Package for Social Sciences version 20.Results Of the 390 and 90 women screened for ASB, prevalence was 20% and 35.5% respectively at Tamale Central and Tamale Teaching Hospital. Sterile pyuria was found among 66% of the 50 women presenting at Tamale Central Hospital. More than 64% of isolates recovered from ASB patients were S. aureus and coagulase negative Staph. ( CoNS ). Escherichia coli was the dominant species among members of the enterobacteriaceae isolated. Highest susceptibility was recorded against gentamicin and amikacin while most resistance was to Ampicillin, cotrimoxazole, chloramphenicol and nitrofurantoin. Resistance to imipenem and vancomycin were 28.8% and 52%, with strains showing multiple drug resistance of between 81-92%.Conclusion The prevalence of asymptomac bacteriuria is appreciably higher (20-35.5%) than documented rates in the southern sector of the country. The presence of sterile pyuria which may be an indication of asymptomatic renal impairment and most often overlooked in antenatal management is 66%. Empirical treatment of UTIs at the Tamale Central and Teaching Hospital without confirmation of susceptibility may result in treatment failure. It is necessary to screen and treat pregnant women for ASB and SP due to the complications associated with these conditions.


2019 ◽  
Author(s):  
Akosua Bonsu Karikari ◽  
Courage Kosi Setsoafia Saba ◽  
David Yembilla Yamik

Abstract Background Asymptomatic bacteriuria (ASB) and sterile pyuria (SP) are complexities of UTI whose prevalence are not known in the northern sector of Ghana. Our aim was to determine the occurrence of sterile pyuria and asymptomatic bacteriuria among pregnant women accessing antenatal care at a secondary and tertiary care hospitals in Tamale, northern Ghana.Methods A cross sectional study was conducted by screening 530 pregnant women with no signs of acute urinary tract infection attending antenatal clinic for a period of 6 months. Midstream urine was collected for microscopy, quantitative urine culture and antibiotic susceptibility testing. Data analysis was carried out using the Statistical Package for Social Sciences version 20.Results Of the 390 and 90 women screened for ASB, prevalence was 20% and 35.5% respectively at Tamale Central and Tamale Teaching Hospital. Sterile pyuria was found among 66% of the 50 women presenting at Tamale Central Hospital. More than 64% of isolates recovered from ASB patients were S. aureus and coagulase negative Staph. ( CoNS ). Escherichia coli was the dominant species among members of the enterobacteriaceae isolated. Highest susceptibility was recorded against gentamicin and amikacin while most resistance was to Ampicillin, cotrimoxazole, chloramphenicol and nitrofurantoin. Resistance to imipenem and vancomycin were 28.8% and 52%, with strains showing multiple drug resistance of between 81-92%.Conclusion The prevalence of asymptomac bacteriuria is appreciably higher (20-35.5%) than documented rates in the southern sector of the country. The presence of sterile pyuria which may be an indication of asymptomatic renal impairment and most often overlooked in antenatal management is 66%. Empirical treatment of UTIs at the Tamale Central and Teaching Hospital without confirmation of susceptibility may result in treatment failure. It is necessary to screen and treat pregnant women for ASB and SP due to the complications associated with these conditions.


2021 ◽  
Vol 3 (1) ◽  
pp. 019-030
Author(s):  
Ramon Sunday Omotayo ◽  
Abayomi Logo ◽  
Adetayo Bade-Adefioye ◽  
Oluseyi Adewale ◽  
Ayomide Emmanuel Sanni

Caesarean Section on maternal request is a planned surgery performed without medical indication, where the wish of the woman compensates for the lack of medical reasons. Preferences for caesarean section are often associated with some factors that may be cultural, economic, religious or social. Some women are said to suffer from tocophobia which is the fear of childbirth and may be a major psychological cause for caesarean section due to maternal request (CSMR). This study explored the popularity of maternally requested caesarean section amongst pregnant women in the Antenatal clinic of University of Medical Sciences Teaching Hospital, Akure. Method: It was a cross-sectional descriptive study. Results: Willingness to request for caesarean section if not indicated is found to be low with only about 10% indicating that they can do so. Rather, refusal to undergo caesarean section when medically indicated is found to be relatively high with 43 % of respondents indicating their unwillingness to have caesarean section even if indicated. Fear of adverse occurrence to mother or baby is the major reason for avoiding caesarean section Conclusion: Maternally requested caesarean section is not popular amongst pregnant women while aversion to indicated caesarean section is high in the study area. There is need for massive education and enlightenment on caesarean section in order to improve its acceptability.


2020 ◽  
Vol 8 (2) ◽  
pp. 5-10
Author(s):  
Ajit Kumar Sah ◽  
Anish Giri ◽  
Anjan Palikhey ◽  
Roshan Kumar Chaurasiya ◽  
Sudeep Kumar Yadav

Background and Objectives: Self-medication can cause significant challenges for the individuals and community, especially in women during pregnancy. The aim of this study was to evaluate the prevalence of self-medication among the pregnant women attending antenatal clinic in a tertiary care center of Nepal. Material and Methods: In this cross-sectional study, a total of 225 pregnant women were evaluated for the prevalence of self-medication during pregnancy. Descriptive statistics and chi-square tests were used for statistical analysis of data. Results: The results showed that the prevalence of self-medication, in pregnant women was 41.3%. The leading illness/ symptoms which led to self-medication among pregnant women attending clinic were to relieve headaches 29 (31.2%), cough 21 (22.6%), vomiting 13 (14%), treat fever 11 (11.8%), urinary tract infections 11 (11.8%) and drugs commonly reported for self-medication were paracetamol (30.10%), cough remedies (19.30%), antiemetics (16.13%), analgesics (10.75%). Conclusion: Prevalence of self-medication among pregnant women is high in Nepal. This is a threat to the safety of the developing foetus and the pregnant woman. Therefore, it seems necessary to provide public trainings for all women of reproductive age and train them about the dangers and side effects of self-medication.


Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 54-63
Author(s):  
Ravi Kumar Shah ◽  
Jagat Prasad Deep ◽  
Zarin Rahman ◽  
Pravin Shah ◽  
Neha Nayak ◽  
...  

Background: Anaemia in pregnancy is a global health challenge. It is the commonest medical disorder of pregnancy and a major cause of morbidity and mortality in developing countries. Main cause of anaemia in obstetrics is iron deficiency. There are specific risks for the mother and the fetus such as intrauterine growth retardation, prematurity, and blood transfusion. Hence, the importance of giving iron in the antenatal period and to be continued postnatally. Objectives: The study was conducted to determine the overall prevalence of anaemia among pregnant women presenting in third trimester and its effect on pregnancy outcome. Methods: This is a cross sectional descriptive study done at National Medical College & Teaching Hospital from September 2015 to August 2016. During the study period 2048 pregnant women attended antenatal clinic in third trimester. Among 2048, 1200 were booked cases and out of these women with haemoglobin less than 11gm/dl were labeled as anaemia. The prevalence was calculated along with the maternal and fetal outcome. Result: Among 2048, 1200 were booked cases, 368 (30.66%) were anemic, 66.30% were multigravida, 67.93% in age group of 21-30 years, 284 patients came for delivery. In 14.08% patients there was preterm labour, apgar score less than 7 in 66.19% babies. Majority of neonate weighed between 2.0 - 2.5kg (49.29%). Perinatal deaths were 2.81%. Conclusion: Anaemia in pregnancy need awareness about early and regular antenatal care with oral iron supplementation. Correction of anaemia will reduce the maternal and fetal complications.  


2013 ◽  
Vol 9 (2) ◽  
pp. 9-14
Author(s):  
S Fatima ◽  
NK Afridi ◽  
S Khan

Introduction: Globally, around 34 million people are living with HIV in 2010, and 35% of the pregnant  women are tested for HIV in the low and middle income countries. HIV infection in pregnancy has  become a complication of pregnancy in some developing countries. This has major implications for  the management of pregnancy and birth. With an estimated one and a half million HIV-positive women  becoming pregnant each year, almost 600,000 children will be infected by mother-to-child transmission  annually. Methodology: A cross sectional study was conducted from October – December 2011 in the Department  of Obstetrics and Gynecology, Khyber Teaching Hospital, Peshawar. It is a tertiary care hospital located  in Peshawar. A sample of 200 pregnant females was used to accomplish the study. The targeted study  population was all antenatal attendees who were visiting the hospital within the current pregnancy. A pre-  coded, pre- tested structured questionnaire was used to gather information on the study variables. The  questionnaire included variables related socio-demographics e.g., age, education status, occupation,  residence. It also included the gestational age and gravidity of the pregnant females. Results: A total of 200 pregnant females attending the antenatal clinic participated in the study. The  age range of the respondents was 17 to 45 years. Age range 17-25 years accounted for the highest  percentage (52%). Around 70% of the respondents had no formal schooling while only 18% had got  secondary education. Ninety – seven percent of the females were housewives while only 3% were  employed. Out of the total respondents (200) only 86 (43%) have heard of HIV while 114 (57%)  respondents have not heard of HIV. Conclusion: The study concluded that only 43% of the pregnant females have heard of HIV. Although  this is not promising still there is room for improvement. Health education targeting pregnant females is  essential. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2012; IX(2) 9-14 DOI: http://dx.doi.org/10.3126/saarctb.v9i2.7972


2017 ◽  
Vol 4 (5) ◽  
pp. 1348
Author(s):  
Manasi Patnaik ◽  
Kumudini Panigrahi ◽  
Banya Das ◽  
Basanti Pathi ◽  
Nirmala Poddar ◽  
...  

Background: Asymptomatic bacteriuria (ASB) is a relatively common condition occurring due to the morphological and physiological changes in the genitourinary tract during pregnancy. If left untreated, it may lead to acute pyelonephritis and adverse fetal and maternal outcomes. The objective was to determine prevalence, risk factors and etiological agents with susceptibility for ASB among pregnant women attending an antenatal clinic at a tertiary care hospital, Odisha, India.Methods: A prospective study with 200 pregnant women was conducted, over a period of 4 months, starting from 1st April 2017 to 31st July 2017. The mid- stream clean catch urine specimen was collected and processed in all the cases and other data were collected from the questionnaire given to them. The isolates from all the cases of ASB were identified and antimicrobial susceptibility was tested by Kirby- Bauer disc diffusion method and interpreted.Results: Prevalence of ASB in our study was 25.3%, with maximum prevalence among age group 21-30 yrs, during 3rd trimester, among multigravidae. Previous history of urinary tract infection (UTI), anaemia and diabetes have significant association with ASB. Klebsiella spp. was the predominant isolate in this study followed by Escherichia coli. Nitrofurantoin and Cefixime are safe and effective antibiotics against urinary pathogens in pregnancy.Conclusions: Undiagnosed and untreated asymptomatic bacteriuria is associated with complications during pregnancy. Hence routine screening of antenatal women for ASB during all trimesters must be considered for preventing the adverse maternal and foetal outcomes particularly with known risk factors like increasing age, multiparity and previous history of UTI.  


During pregnancy, most women are at risk for respiratory tract infections (RTIs), urinary tract infections (UTIs), and ear, nose, and throat infections. Antimicrobials are the most commonly given medications to treat acquired illnesses during this time. This study aimed to assess antibiotic use in pregnant women in a tertiary care teaching hospital. The present study was a cross- sectional prospective observational study and was conducted for three months in a tertiary care health centre in North Karnataka with 57 participants.All case records of pregnant women who use antibiotics admitted to Obstetrics and Gynecology department and pregnant women with more than 18 years of age were included in the study. Out of 57 participants, 40.3% of them were belonging to the age category of 19-23 years of age, followed by 33.3% in 24-28 years. Most prevalent infections which required antimicrobials prescription were UTIs (36.82%), followed by Gastroenteritis (17.54%) and Pyrexia (14.03%). Majority of the antimicrobials prescribed were from Betalactams (40.34%), followed by Nitrofuranes (29.82%). To assist in making prescribing decisions for pregnant women, health care professionals should examine the teratogenic and toxic risk profiles of antibiotics. These could be especially significant if anti- infective countermeasures are needed to safeguard the health, safety, and survival of people who have been exposed to pathogenic bacteriologic agents as a result of bioterrorism. Keywords: Antimicrobials, pregnancy, teratogenic effect, urinary tract infections


Author(s):  
Shadrack Okaijah ◽  
Albert Abaka-Yawson ◽  
Philip Apraku Tawiah ◽  
Solomon Sosu Quarshie ◽  
George Yiadom Osei ◽  
...  

Background: The significance of asymptomatic bacteriuria (ASB) relates to its potential to cause acute pyelonephritis, preterm labour and preterm rupture of the membranes. Additionally, it has been associated with clinical conditions such as anaemia, preterm birth, low birth weight and perinatal mortality. Aim: This study, therefore, determined the prevalence of ASB among pregnant women attending the antenatal clinic.  Materials and Methods: A cross-sectional study using convenient sampling method was used to recruit 200 pregnant women attending antenatal care at the Korle-Bu Teaching Hospital (KBTH) from January – April 2014. Bacteriological, urine chemistry and routine urine analyses, as well as antibiotic susceptibility profile of bacterial isolates from mid-stream urine samples of pregnant women, were carried out using appropriate standard methods. Variables were reported in mean, standard deviation, percentages and bar graph. Chi-square test was used to establish statistical difference and association between variables where p-value <0.05 was considered statistically significant. Results: Out of the total participants, 23 had asymptomatic bacteriuria but no prevalence of ASB was found among Muslims. The association between marital status and the prevalence of ASB was significant (Pearson chi2 = 4.88, p-value = 0.027). Five bacterial isolates were obtained with Escherichia coli (43.6%) being the most prevalent organism. There were more negative reactions than positive reactions with regards to nitrite and leukocyte esterase determination. Both gram-positive and negative isolates recorded high susceptibility to Gentamicin and Norfloxacin. However, Ciprofloxacin showed a high rate of resistance to only gram-negative isolates whiles Chloramphenicol, Ampicillin and Amoxicillin showed high resistance to gram-positive isolates. Conclusions: The overall prevalence of asymptomatic bacteriuria was 11.5% [95%CI: 7.4% - 16.8%] among the referral pregnant women attending KBTH with Escherichia coli being the most prevalent organism whiles the most susceptible antibiotics were Gentamicin and Norfloxacin.


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