scholarly journals Clinical course and characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou: A Retrospective study

2020 ◽  
Author(s):  
Fenhua Lai ◽  
Yongtao Zheng ◽  
Hexiang Jia ◽  
Fuliang Wang ◽  
Xiangjue Sun ◽  
...  

Abstract Background: The World Health Organization declared the outbreak a public health emergency of international concern (Corona Virus Disease 2019) on January 30th, this study aimed to investigate the epidemiological and clinical characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou, and evaluate scientific basis for disease control and prevention. Methods: A total of 30 patients had been admitted to hospital from Jan 22 to Feb 22, 2020, all of them were laboratory confirmed SARS-Cov-2. Demographic, epidemiological, clinical, laboratory data were collected from Hospital information system and Epidemiological investigation reports. All data was performed by descriptive analysis, Chi-square test or non-parametric Mann-Whitney U test, as appropriate. Two sided p value less than 0.05 was considered statistically significant.Results: 30 patients were enrolled, the median age was 44.5 years (IQR 33.8-52.3) and 17 (56.7%) patients were female, 14 (46.7%) patients were native and had no exposure to Hubei Province. At the time of study submission, only one patient had not been discharged and no patients died during the study. The median hospital stay was 16.0 days (IQR 12.5-20.5) and the median course of disease was 20.5 days (IQR 17.0-23.3). The most common symptoms were fever (66.7%), dry cough (26.7%), and pharyngalgia (23.3%) on first admission. Most patients were generally illness or more mild, but 10 (33.3%) patients received oxygen therapy and 14 (46.7%) patients received hormone therapy during their hospitalization. Almost half of patients showed mild lymphocytopenia and 40% patients had elevated concentrations of CRP in the early stages of COVID-19.Conclusions: Among the 30 patients were confirmed with SARA-Cov-2 infection in Xiaoshan, Hangzhou, most of them had clinical presentation of respiratory tract infection, but the median course of disease was more than 2 weeks. Further systematic prospective studies about COVID-19 should be urgently needed.

2020 ◽  
Vol 8 (8) ◽  
pp. 4211-4215
Author(s):  
Priyanka V ◽  
Yogesh Jakhar ◽  
Anupam Pathak

The outbreak of Corona virus disease (COVID-19) has been recently declared as Public Health Emergency of International Concern (PHEIC) by World Health Organization and the virus has now spread beyond the boundaries of countries and continents. At present, no specific antiviral treatment or vaccine is available or recommended to counter the COVID-19, and the potential therapy is still symptomatic. The outbreak of the Corona virus was begun in Wuhan, China in December 2019. The most common symptoms are fever, tiredness and dry cough. Some individuals also develop aches and pains, nasal congestion, runny nose, sore throat, or diarrhea. It was reported that traditional remedies may alleviate the symptoms of COVID19. Ayurveda is the world’s oldest medical system that can manage any disease without side effects. Ayurveda is equipped with varieties of treatment modalities to handle with any type of deadly diseases. However, a major drawback is a lack of adequate scientific basis. In recent time, a branch of modern medical science has developed and is known as Psycho- Neuro -Immunology. It deals with the phenomenon of how our thoughts and emotions can affect our immune system. Stress, fear and negative emotions are known to weaken our immune system while Yoga (including meditation), mindfulness, positive emotions, and relaxa-tion strengthen it. Yoga plays an important role to strengthen our immune system.


2021 ◽  
Vol 38 (1) ◽  
Author(s):  
Kaleem Ullah Toori ◽  
Asma Chaudhry ◽  
Muhammad Arsalan Qureshi

Objectives: To identify association of epidemiological characteristics, presence of underlying pre-morbidities and disease severity with time to first negative PCR in Corona virus disease 2019. Methods: Total 842 Corona Virus Real Time Polymerase-Chain-Reaction positive patients were included in this cross-sectional study. Patients were admitted to Department of Medicine at KRL Hospital Islamabad from April to August 2020. Age, gender, symptoms, pre-morbidities and disease severity were recorded. Outcome (recovered versus died) was documented. World Health Organization categories to classify disease severity (asymptomatic, mild, moderate and severe) were used. Time to negative PCR was documented as time between first positive PCR to first negative PCR. Results: The mean age of patients was 39.04 ± 11.32 years with 99.8% being males. Majority of patients (78.4%) were asymptomatic. Amongst symptoms, fever was the most common symptom. Diabetes mellitus and hypertension were the most commonly recorded co-morbidity. Mean time to negative PCR was 8.8 ± 3.1 days. A large proportion of patients recovered (99.9%). Significant positive correlation (p value < 0.05) was found between age, gender, presence of underlying pre-morbidities and disease severity categories with time to first negative PCR. Conclusion: The underlying epidemiological factors, pre-morbidities and disease severity are associated with time to negative PCR and hence affect frequency of recovery samples. doi: https://doi.org/10.12669/pjms.38.1.4476 How to cite this:Toori KU, Chaudhry A, Qureshi MA. Time to negative PCR in various disease categories of COVID-19 infection in Pakistani population. Pak J Med Sci. 2022;38(1):---------. doi: https://doi.org/10.12669/pjms.38.1.4476 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2021 ◽  
Author(s):  
Amit Kumar Saxena

AbstractIntroductionSevere Acute Respiratory Syndrome Corona virus-2 (SARS-CoV-2) spread mainly through respiratory droplets and contact routes. Long term use of spectacles may prevent repeated touching and rubbing of the eyes. Aim of the study is to find out the protective effectiveness of the spectacles against COVID-19, if present.ObjectivesTo know the association between infection with SARSCoV-2 and wearing of spectacles.Materials and methodsIn this study, 304 patients of Corona virus disease 2019 (COVID-19) were selected. Their spectacles wearing behaviour were assessed through a questionnaire. Spectacles wearing behaviour of general population were obtained from older studies (for comparison). Data was put in the tabulate form and Chi- Square test was used for statistical analysis.ResultsIn this study, among the 304 total patients, 58 patients showed the behavior of using spectacles continuously during day time and always on outdoor activities. While the spectacles wearing behaviour is about 40% among general Indian population. The protective effectiveness of the spectacles was found statistically significant (p-value. 00113).ConclusionThe present study showed that the occurrence of Covid-19 was less in spectacles wearing population than the population not wearing those. The nasolacrimal duct may be a route of virus transmission from conjunctival sac to the nasopharynx.


Author(s):  
Dini Kesumah Dini Kesumah

ABSTRACT According to World Health Organization Health Organization (WHO) in 2005 showed 49% of deaths occur in children under five in developing countries. Nutritional problems can not be done with the medical and health care approach alone. Causes related to malnutrition that maternal education, socioeconomic families, poor environmental sanitation, and lack of food supplies. This study aims to determine the relationship between education and socioeconomic status of families with nutrition survey using a cross sectional analytic approach, with a population of all mothers of children under five who visited the health center in Palembang Keramasan Accidental sampling Sampling the number of samples obtained 35 respondents. Variables include the study independent and dependent variables and univariate analysis using Chi-Square test statistic with a significance level α = 0.05. The results from 35 respondents indicate that highly educated mothers earned as many as 16 people (45.7%), and middle and upper income families as many as 12 people (34.3%) and bivariate test results show that highly educated respondents toddler nutritional status good for 81.3% (13 people) is larger than the less educated respondents balitanya good nutritional status 26.3% (5 persons) as well as respondents who have middle and upper socioeconomic families with good nutritional status of children at 91.7% ( 11 people) is larger when compared to respondents who have family socioeconomic medium with good nutritional status of children at 30.4% (7 people). Statistical tests show that education has a significant relationship with nutritional status of children P value = 0.004 and socioeconomic families have a meaningful relationship with nutritional status of children P value = 0.002. Based on the results of the study suggested the health professionals in the health center should further improve the education, information about the importance of nutrition to the development of the child in the mothers through the selection and processing of good food and a good diet through health centers and integrated health.   ABSTRAK  Menurut badan kesehatan World Health Organization (WHO) tahun 2005 menunjukkan 49% kematian yang terjadi pada anak dibawah umur lima tahun di negara berkembang. Masalah gizi ini tidak dapat dilakukan dengan pendekatan medis dan pelayanan kesehatan saja. Penyebab yang berhubungan dengan kurang gizi yaitu pendidikan ibu, sosial ekonomi keluarga, sanitasi lingkungan yang kurang baik,dan kurangnya persediaan pangan. Penelitian ini bertujuan untuk mengetahui hubungan antara pendidikan dan sosial ekonomi keluarga dengan status gizi balita dengan menggunakan metode survei analitik pendekatan secara Cross Sectional, dengan populasi semua ibu yang memiliki anak balita yang berkunjung ke Puskesmas Keramasan Palembang dengan pengambilan sampel secara Accidental Sampling diperoleh jumlah sampel 35 responden. Variabel penelitian meliputi variabel independen dan dependen serta analisis univariat menggunakan uji statistik Chi-Square dengan tingkat kemaknaan α = 0,05. Hasil penelitian ini menunjukkan dari 35 responden didapatkan ibu yang berpendidikan tinggi sebanyak 16 orang  (45,7%), dan keluarga yang berpenghasilan menengah keatas sebanyak 12 orang (34,3%) dan hasil uji bivariat menunjukkan bahwa responden yang berpendidikan tinggi status gizi balitanya baik sebesar 81,3% (13 orang) lebih besar bila dibanding responden yang berpendidikan rendah status gizi balitanya baik 26,3% (5 orang) serta responden yang mempunyai sosial ekonomi keluarga menengah keatas dengan status gizi balita baik sebesar 91,7% (11 orang) lebih besar bila dibanding responden yang mempunyai sosial ekonomi keluarga menengah kebawah dengan status gizi balita baik sebesar 30,4% (7 orang). Uji statistik menunjukkan bahwa pendidikan mempunyai hubungan yang bermakna dengan status gizi balita P value = 0,004 dan sosial ekonomi keluarga mempunyai hubungan yang bermakna dengan status gizi balita P value = 0,002. Berdasarkan hasil penelitian disarankan pada petugas kesehatan di Puskesmas hendaknya lebih meningkatkan penyuluhan-penyuluhan tentang pentingnya gizi terhadap tumbuh kembang anak pada ibu-ibu melalui cara pemilihan dan pengolahan bahan makanan yang baik serta pola makanan yang baik melalui kegiatan Puskesmas dan Posyandu.


Author(s):  
Leny Leny

ABSTRACT Prenatal care is health care by health personnel to care the pregnant according to standards. Worlrd Health Organization (WHO) estimates more than 500.000 women die during pregnancy or childbirth. Maternal mortality in Indonesia is 307 per 100,000 live births. The quantity of pregnant women’s visit in Kabupaten Banyuasin in 2009 of 89.1%. The purpose of this study to determine the relationship between education and occupation with prenatal care at Puskesmas Mariana  Kecamatan Banyuasin I Kabupaten Banyuasin in 2011. This study uses analytic approach survey by Cross Sectional methods, the population are 1.946 pregnant women and the samples as many as 332 people. The results of univariate analysis study of pregnant women who are higher education as much as 45.2%, and  low maternal education as much as 54.8%. In pregnant women who work of 43.4%, and pregnant women who do not work for 56.6%. From the results of bivariate analysis and Chi-Square statistical tests found a significant association between education of pregnant women with prenatal care with P Value = 0.000, and there was a significant association between occupation of pregnant women with prenatal care with P Value = 0.000. Can be concluded that there is a relationship between education and occupation of pregnant women with prenatal care. Expected to health workers to provide counseling on the importance of prenatal care in pregnant women and expected future studies may explore again the factors associated with prenatal care with the different variables.   ABSTRAK Pemeriksaan kehamilan adalah pelayanan kesehatan oleh tenaga kesehatan untuk memeriksakan ibu hamil sesuai standar. World Health Organization (WHO) memperkirakan lebih dari 500.000 ibu pertahunnya meninggal saat hamil atau bersalin. AKI di Indonesia 307 per 100.000 kelahiran hidup. Jumlah kunjungan ibu hamil di Kabupaten Banyuasin tahun 2009 sebesar 89,1%. Tujuan penelitian ini untuk mengetahui hubungan antara pendidikan dan pekerjaan dengan pemeriksaan kehamilan di Puskesmas Mariana Kecamatan Banyuasin I Kabupaten Banyuasin tahun  2011. Penelitian ini menggunakan metode survey analitik dengan pendekatan Cross Sectional, populasi ibu hamil dengan jumlah 1.946 orang dan jumlah sampel sebanyak 332 orang. Hasil penelitian Analisa Univariat adalah ibu hamil yang pendidikan tinggi sebanyak 45,2%, dan pendidikan rendah ibu hamil sebanyak 54,8%. Pada variabel pekerjaan ibu hamil yang bekerja sebesar 43,4%, dan ibu hamil yang tidak bekerja sebesar 56,6%. Dari hasil analisa bivariat dan uji statistik Chi-Square  didapatkan hubungan yang bermakna antara pendidikan ibu hamil dengan pemeriksaan kehamilan dengan  P Value = 0,000, dan ada hubungan yang bermakna antara pekerjaan ibu hamil dengan pemeriksaan kehamilan dengan P Value = 0,000. Dapat disimpulkan bahwa ada hubungan antara pendidikan dan pekerjaan ibu hamil dengan pemeriksaan kehamilan. Diharapkan kepada petugas kesehatan agar dapat memberikan penyuluhan tentang pentingnya pemeriksaan pada ibu hamil dan diharapkan penelitian yang akan datang dapat menggali lagi faktor-faktor yang berhubungan dengan pemeriksaan kehamilan dengan variabel yang berbeda.


2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Dina Ardyana ◽  
Erma Puspita Sari

Latar belakang: Berdasarkan data World Health Organization (WHO) setiap tahunnya kira-kira 3%(3,6 juta) dari 120 juta bayi baru lahir mengalami asfiksia,hampir 1 juta bayi ini meninggal. Di Amerika diperkirakan 12.000 bayi meninggal atau menderita kelainan akibat asfiksia perinatal.Sebagian kasus Asfiksia Neonatorum pada bayi baru lahir merupakan kelanjutan dari asfiksia intrauterin. Maka dari itu,diagnosa dini pada penderita Asfiksia merupakan arti penting dalam merencanakan resusitasi yang akan dilakukan.Setelah bayi lahir, diagnosa asfiksia dapat dilakukan dengan menetapkan nilai APGAR. Tujuan: diketahuinya hubungan lilitan tali pusat,partus lama dan plasenta previa dengan kejadian Asfiksia neonatorum di Rumah Sakit “P” Palembang Tahun 2018. Metode: Jenis penelitian yang digunakan adalah survey analitik dengan pendekatan cross sectional. Populasi dalam penelitian seluruh ibu bersalin di zal kebidanan di Rumah Sakit “P” Palembang pada tahun 2018 yang berjumlah 820 orang. Hasil: Hasil analisis univariat diketahui yang mengalami asfiksia neonatorum sebanyak 20 responden (22,5%),yang mengalami plasenta previa sebanyak 15 responden(16,9%),yang mengalami partus lama sebanyak 20 responden (22,5%) dan yang mengalami lilitan tali pusat sebanyak 27 responden (30,3%).Sedangkan hasil uji chi square menunjukan ada hubungan plasenta previa dengan kejadian asfiksia neonatorum dengan p value = 0,000,ada hubungan partus lama dengan kejadian asfiksia neonatorum dengan p value = 0,000,dan ada hubungan lilitan tali pusat dengan kejadian asfiksia neonatorum dengan p value = 0,000. Saran: kepada Pimpinan Rumah Sakit untuk meningkatkan mutu pelayanan kesehatan khususnya mengenai bahaya asfiksia neonatorum. Kata kunci : Lilitan Tali Pusat,Partus Lama,Plasenta Previa,Asfiksia Neonatorum


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Marco Cattalini ◽  
◽  
Sara Della Paolera ◽  
Fiammetta Zunica ◽  
Claudia Bracaglia ◽  
...  

Abstract Background There is mounting evidence on the existence of a Pediatric Inflammatory Multisystem Syndrome-temporally associated to SARS-CoV-2 infection (PIMS-TS), sharing similarities with Kawasaki Disease (KD). The main outcome of the study were to better characterize the clinical features and the treatment response of PIMS-TS and to explore its relationship with KD determining whether KD and PIMS are two distinct entities. Methods The Rheumatology Study Group of the Italian Pediatric Society launched a survey to enroll patients diagnosed with KD (Kawasaki Disease Group – KDG) or KD-like (Kawacovid Group - KCG) disease between February 1st 2020, and May 31st 2020. Demographic, clinical, laboratory data, treatment information, and patients’ outcome were collected in an online anonymized database (RedCAP®). Relationship between clinical presentation and SARS-CoV-2 infection was also taken into account. Moreover, clinical characteristics of KDG during SARS-CoV-2 epidemic (KDG-CoV2) were compared to Kawasaki Disease patients (KDG-Historical) seen in three different Italian tertiary pediatric hospitals (Institute for Maternal and Child Health, IRCCS “Burlo Garofolo”, Trieste; AOU Meyer, Florence; IRCCS Istituto Giannina Gaslini, Genoa) from January 1st 2000 to December 31st 2019. Chi square test or exact Fisher test and non-parametric Wilcoxon Mann-Whitney test were used to study differences between two groups. Results One-hundred-forty-nine cases were enrolled, (96 KDG and 53 KCG). KCG children were significantly older and presented more frequently from gastrointestinal and respiratory involvement. Cardiac involvement was more common in KCG, with 60,4% of patients with myocarditis. 37,8% of patients among KCG presented hypotension/non-cardiogenic shock. Coronary artery abnormalities (CAA) were more common in the KDG. The risk of ICU admission were higher in KCG. Lymphopenia, higher CRP levels, elevated ferritin and troponin-T characterized KCG. KDG received more frequently immunoglobulins (IVIG) and acetylsalicylic acid (ASA) (81,3% vs 66%; p = 0.04 and 71,9% vs 43,4%; p = 0.001 respectively) as KCG more often received glucocorticoids (56,6% vs 14,6%; p < 0.0001). SARS-CoV-2 assay more often resulted positive in KCG than in KDG (75,5% vs 20%; p < 0.0001). Short-term follow data showed minor complications. Comparing KDG with a KD-Historical Italian cohort (598 patients), no statistical difference was found in terms of clinical manifestations and laboratory data. Conclusion Our study suggests that SARS-CoV-2 infection might determine two distinct inflammatory diseases in children: KD and PIMS-TS. Older age at onset and clinical peculiarities like the occurrence of myocarditis characterize this multi-inflammatory syndrome. Our patients had an optimal response to treatments and a good outcome, with few complications and no deaths.


2020 ◽  
Vol 5 (02) ◽  
pp. 29-42
Author(s):  
Samfriati S ◽  
Friska G ◽  
Lia Mayang S S

Background: In the Covid-19 Pandemic era 2020, Covid-19 with its increasing spread rate even death in each individual can occur, this greatly affects the condition of students universally by experiencing annoyance, worry, fear, anxiety so that it can cause excessive anxiety. One of the techniques to reduce this level of anxiety is the Benson Relaxation, which can provide comfort and a sense of relaxation so that it can adapt well to the current environment. This Benson relaxation is a combination of deep breaths and elements of faith that give a feeling of calm, comfort and even confidence.Goals: The purpose of this study was to determine the effect of Benson Relaxation on the Anxiety Levels of Corona virus disease 2019 on nursing students level III of STIKes Santa Elisabeth Medan 2020.Method: This study used a pre-experimental study with one group pre test and post test design. The instrument used was an anxiety level questionnaire, with 30 nursing students level III STIKes Santa Elisabeth Medan. The research sample were 30 students, where the sample was used by using purposive sampling.Result: The results of the study p-value = 0.000 (P <0.05) indicate that Benson relaxation has an effect on the anxiety level of the third level of Nursing student STIKes Santa Elisabeth Medan.Conclusion: This Benson relaxation technique is a good and appropriate relaxation to do at this time to reduce the level of anxiety in the respondent so that the respondent experiences a sense of calm and comfort. Respondents are expected to always apply this Benson relaxation to overcome the increasing increase in anxiety and can overcome the level of anxiety they are experiencing


2019 ◽  
Vol 2 (1) ◽  
pp. 57
Author(s):  
Jumiati Jumiati

Pendahuluan : Abortus menjadi masalah yang penting dalam kesehatan masyarakat karena berpengaruh terhadap morbiditas dan mortalitas maternal. Berdasarkan data World Health Organization (WHO) tahun 2016, sekitar 830 wanita meninggal akibat komplikasi terkait kehamilan di seluruh dunia setiap hari. Selama 2010–2014, diperkirakan 56 juta abortus terjadi setiap tahun di seluruh dunia. Tujuan : untuk mengetahui faktor-faktor yang berhubungan dengan abortus di RSU Mutia Sari Duri periode 2017. Metode : penelitian ini menggunakan survei analitik dengan pendekatan cross sectional. Populasi penelitian ini adalah seluruh ibu hamil yang mengalami abortus di RSU Mutia Sari Duri periode 2017 yang berjumlah 86 orang. Sampel dalam penelitian ini adalah total sampling  yaitu seluruh populasi. Uji statistik yang digunakan adalah uji statistik Chi-square. Hasil : data yang diperoleh dari hasil uji statistik menunjukkan ada hubungan jarak kehamilan dengan abortus didapat hasil p value 0,04 (p<0,05), tidak ada hubungan usia dengan abortus didapat hasil p value 0,48 (p>0,05), ada hubungan paritas dengan abortus didapat hasil p value 0,03 (p<0,05), dan ada hubungan pekerjaan dengan abortus didapat hasil p value 0,04 (p<0,05).Kesimpulan : penelitian ini adalah ada hubungan jarak kehamilan, paritas dan pekerjaan ibu hamil dengan abortus dan tidak ada hubungan usia ibu hamil dengan abortus di RSU Mutia Sari Duri periode 2017.


2021 ◽  
Vol 30 (02) ◽  
pp. 103-106
Author(s):  
Ajeet Kumar ◽  
◽  
Naveed Iqbal ◽  
Javaria Farooq ◽  
Saad Uddin Siddiqui

OBJECTIVE: This study was performed to compare incidence of perforations in Latex and Nitrile examination gloves during Minor Oral surgical procedures performed under local anesthesia. METHODOLOGY: 100 pairs of latex and 100 pairs of Nitrile examination gloves where used to perform 200 minor oral surgical procedures under local anesthesia. After completion of every minor oral surgical procedure each gloves was examined by Water Inflation method to observe presence or absence of Perforations. A data sheet was used to collect data including type of Gloves used (Latex or Nitrile) presence of perforations, sites of perforations and nature of minor oral surgical procedures. Data was entered and analyzed using SPSS version 20. Descriptive analysis was conducted to calculate frequency and percentages of Number and sites of perforations for both Nitrile and latex examination gloves. Chi Square test was used to find out statistical significance of difference of perforations rate between Nitrile and Latex gloves. P value of < 0.05 was considered significant. RESULTS: Out of 200 latex gloves 23 (11.5) had 29 perforations whereas out of total 200 Nitrile gloves 28 (14%) had 22 perforations. Nitrile gloves had a statistically significant higher rate of perforations as compared to Latex gloves. (P value 0.043). For both Nitrile and Latex gloves left non dominant hand had highest frequency of perforations Latex 18 (81.81%) perforations and Nitrile 18(62.06%). Index finger and thumb were most frequent sites of perforations in both Latex and Nitrile gloves. CONCLUSION: Gloves perforations were more common in Nitrile examination gloves however total number of perforations was more in Latex examination gloves.


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