scholarly journals Time to negative PCR in various disease categories of COVID-19 infection in Pakistani population

2021 ◽  
Vol 38 (1) ◽  
Author(s):  
Kaleem Ullah Toori ◽  
Asma Chaudhry ◽  
Muhammad Arsalan Qureshi

Objectives: To identify association of epidemiological characteristics, presence of underlying pre-morbidities and disease severity with time to first negative PCR in Corona virus disease 2019. Methods: Total 842 Corona Virus Real Time Polymerase-Chain-Reaction positive patients were included in this cross-sectional study. Patients were admitted to Department of Medicine at KRL Hospital Islamabad from April to August 2020. Age, gender, symptoms, pre-morbidities and disease severity were recorded. Outcome (recovered versus died) was documented. World Health Organization categories to classify disease severity (asymptomatic, mild, moderate and severe) were used. Time to negative PCR was documented as time between first positive PCR to first negative PCR. Results: The mean age of patients was 39.04 ± 11.32 years with 99.8% being males. Majority of patients (78.4%) were asymptomatic. Amongst symptoms, fever was the most common symptom. Diabetes mellitus and hypertension were the most commonly recorded co-morbidity. Mean time to negative PCR was 8.8 ± 3.1 days. A large proportion of patients recovered (99.9%). Significant positive correlation (p value < 0.05) was found between age, gender, presence of underlying pre-morbidities and disease severity categories with time to first negative PCR. Conclusion: The underlying epidemiological factors, pre-morbidities and disease severity are associated with time to negative PCR and hence affect frequency of recovery samples. doi: https://doi.org/10.12669/pjms.38.1.4476 How to cite this:Toori KU, Chaudhry A, Qureshi MA. Time to negative PCR in various disease categories of COVID-19 infection in Pakistani population. Pak J Med Sci. 2022;38(1):---------. doi: https://doi.org/10.12669/pjms.38.1.4476 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

2021 ◽  
Vol 7 (2) ◽  
pp. 68-74
Author(s):  
Lenny Astuti ◽  
Lily Marleni ◽  
Lela Aini

Tujuan penelitian ini adalah untuk mengetahui apakah ada hubungan Motivasi Belajar Mahasiswa Program Studi D-III Keperawatan Sekolah Tinggi Ilmu Kesehatan Siti Khadijah Palembang Tahun 2020. Rancangan penelitian yang digunakan adalah deskriptif analitik dengan pendekatan cross sectional. Desain tersebut dipilih karena penelitian, pengukuran atau pengamatan dilakukan secara bersamaan (sekali waktu) dan untuk melihat hubungan antara variabel independen dan variabel dependen. Jumlah sampel dalam penelitian ini yaitu sebanyak 113 responden. responden yang mengalami stress berat sebanyak 57 responden (50,4%) lebih banyak dibandingkan dengan responden yang mengalami stress ringan sebanyak 56 responden (49,6%). responden yang memiliki motivasi kuat sebanyak 99 respoden (87,6%) lebih banyak di bandingkan dengan responden yang memiliki motivasi sedang sebanyak 12 responden (10,6 %) dan motivasi lemah sebanyak 2 responden (1,8 %). Tidak Ada hubungan bermakna antara tingkat stress dan motivasi belajar dengan nilai p value 0,846.


2021 ◽  
Vol 51 (1) ◽  
Author(s):  
Indra Zachreini ◽  
Jenny Bashiruddin ◽  
Susyana Tamin ◽  
Harim Priyono ◽  
Ika Dewi Mayangsari ◽  
...  

ABSTRACTBackground: World Health Organization (WHO) announced a newly discovered virus that first identified in Wuhan, China on December 2019, namely SARS-CoV-2 as the cause of corona virus disease (COVID-19) which had become global pandemic. Doctors as medical practitioners are categorized as vulnerable group to be infected by corona virus, and many otorhinolaryngologists had been infected and even died in performing medical services. Among the causative factors why otorhinolaryngologists could get infected by corona virus is their behavior. Purpose: To assess the behavioral level of otorhinolaryngologists in medical services during Covid-19 pandemic. Method: Descriptive study with a cross sectional design. Research samples were otorhinolaryngologists in Indonesia who met the inclusions criteria. The samples were selected by consecutive sampling method, and got obtained 1299 subjects. Behavioral level was assessed from 3 aspects: knowledge, attitude, and practice, which were comprised of 12 questions. Result: It was found that 461 respondents had a good behavioral level (35.5%), 677 respondents had moderate levels (52.1%) and 161 respondents had low level (12.4%). There was a statistically significant correlation between knowledge with behavioral level, attitude with behavioral level, and practice with behavioral level (p=0.001). Conclusion: The study of behavioral level of otorhinolaryngologists in medical service during Covid-19 pandemic obtained the highest number was moderate level 677 respondents (57.2%), and there was a statistically significant correlations between the variable of knowledge with behavioral level, the variable of attitude with behavioral level, and the variable of practice with behavioral level (p=0.001).


2021 ◽  
Vol 6 (3) ◽  
pp. 158-166
Author(s):  
Abdul Muis ◽  
Muhammad Rifai ◽  
Rahmawati Azis

World Health Organization (WHO) has shown Corona Virus Disease 2019 as a pandemic. The spread of COVID-19 in Indonesia has now spread across locations and across countries, accompanied by an increase in the number of problems and/or the number of deaths. To overcome the spread of Covid-19, both the government and business actors have made various efforts so that the spread of the Covid-19 virus can be prevented and overcome, especially the spread of the Covid-19 virus in office areas by implementing new normal rules in the workplace through the Occupational Safety and Health program. Based on the results of observations from one of the lead managers of PT Maruki International Indonesia, who said that there had been cases against some of his employees who were suspected of being suspected of having COVID-19, we as authors consider it necessary to raise this issue to be investigated for input for the company so that it can be used to implement the implementation. Occupational Health and Safety program against suspected cases of the Covid-19 virus among PT Maruki International Indonesia employees. The purpose of this study was to determine the effect of the implementation of the Occupational Health and Safety Program on the incidence of suspected Covid-19 virus among employees of PT Maruki International Indonesia. This type of research is quantitative research with a design approach cross sectional study. The sample used is 150 employees from a population of 241 employees. Collecting quantitative data using a checklist and analyzed by univariate, bivariate. Thus, it can be said that the Behavioral Improving Body Immunity variable affects the variable incidence of suspected covid-19. It is hoped that with the results of this study the government and related company management can provide a policy to deal with the spread of the corona virus in the workplace. Keywords: Activities of wearing masks; hand washing habits; efforts to maintain distance and suspected cases of covid-19.


Author(s):  
Sherin Ann Thomas ◽  
Asish R ◽  
Vinimol C ◽  
Bindu V Bhaskar ◽  
Jesmith Elsa Jacob

Corona virus disease officially called as COVID-19, declared a “pandemic” by the World Health Organization; became a major public health problem causing worldwide morbidity and mortality, despite various control measures. Extraordinary measures are taken universally to fight the spread of the ongoing outbreak. In such a scenario, people’s adherence to preventive measures is largely influenced by their knowledge and perception of the disease. Since dental care professionals are having high chances of infectivity, which in turn has serious implications, it is essential that the auxiliary dental staff must be educated, empowered and provided appropriate and relevant knowledge of the disease.To assess the level of awareness regarding COVID-19 among auxiliary dental staff in a Tertiary Dental Care Centre in Kerala. A cross sectional survey was conducted among all the auxillary staff in a tertiary dental care centre by an online questionnaire through google forms. Details regarding demographic data, knowledge about the spread, symptoms, diagnosis, prevention and safety practices related to COVID-19 were obtained after getting an online informed consent. Descriptive statistics and Chi square test were done. Associations and differences were considered significant when the p value was less than 0.05.The initial sample size was 50. Forty two participants completed the study. Out of the participants 36% (n=15) were below 40 years and were males. About 40.5% (n=17) had experience less than 5 years. Around 69% (n=23) of the participants had good knowledge regarding COVID 19. Statistically significant results were seen with mode of transmission of Covid 19 and age of the respondents (p value=.006);current treatment of Covid 19 and years of experience of the respondents (p value=.011).The study concluded that there is overall good awareness level among the participants of the study.


2021 ◽  
Vol 28 (7) ◽  
pp. 1039-1043
Author(s):  
Hafiz Mughees Ather ◽  
◽  
Arfan Mahmood ◽  
Affan Shahid ◽  
Mohammed Osama ◽  
...  

Objective: To record the epidemiological, characteristics of Acute hepatitis patients. Study Design. Cross Sectional study. Setting: Government General Hospital Ghulam Muhammad Abad, Faisalabad. Period: March 2019 to 30th of September 2019. Material & Methods: A total of 92 patients included in the study. Patient’s epidemiological characteristics, symptoms and lab results were recorded during hospital stay. Categorical variables were analyzed using Chi-Square and Fissure Exact tests. P value of <0.05 was considered statistically significant. Results: 78% were male & 22% were female. Water source was 16% filtered water, 32% ground water & 52% was Government supplied water. Most common symptom was yellow sclera (100%), Dark urine (100%), Nausea, fatigue and anorexia (Each 87%), Vomiting (83%), Fever (73%), Right hypochondriac pain (70%), Body aches (66%) and headache was 61%. Among the risk factors other than water source, outside eating was present in 74% and tattooing was present in 5% while blood transfusion history and Ear/Nose piercing was 0%. All 92 patients discharged in stable condition (100%). Tests for determination of cause i.e HAV & HEV serology were ordered in each case. Conclusion: Young males were affected more commonly. Presentation of acute hepatitis varies in symptoms but mostly the disease is self-limiting and running a mild course without leading to liver failure. Most common risk factor was outside eating in unhygienic environment which should be avoided.


Author(s):  
Shatrughan Pareek ◽  
Narendra Kumar Kaushik ◽  
Diwakar Verma ◽  
Anupam Pareek ◽  
Yashawant Ramawat ◽  
...  

Background: Corona virus disease (COVID-19) is declared pandemic by the WHO.  It is a very contagious disease. The global mortality rate of Corona virus disease is around 3.1%. The study was conducted with aim to assess the knowledge and practices towards Corona virus disease among urban population. Awareness towards the disease is important for prevention and control.Methods: The research design was community based descriptive cross-sectional design. The study was conducted in selected urban communities of Bikaner district, Rajasthan. A structured knowledge questionnaire and Practice scale were distributed to subjects from March 2020 to April 2020. In present study, 327 subjects were included in the study by random sampling technique. Data analysis was done using SPSS version 22.0.Results: In the present study, 56.27% were male and 43.73% were female. Nearly 70% participants were graduate and above in educational status. In present study, mostly subjects (76%) have average to good knowledge and practice towards COVID-19. Finding of the study suggests that there was a weak correlation between knowledge and practices of urban people towards corona virus infection. The correlation was not significant (p value=0.1976) at 0.05 level of significance. The study also revealed that knowledge has association with only educational qualification and gender shown association with practices of urban population.Conclusions: Knowledge and practices among population towards the disease are crucial to minimize morbidity and mortality due to the disease. The people have knowledge towards corona virus infection but they are not implementing it into practice. 


Author(s):  
Subrata Baidya ◽  
Debosmita Paul ◽  
Purvita Chowdhury

A cluster of pneumonia cases of unknown aetiology was reported from Wuhan, Hubei province of China on 31st December, 2019. The World Health Organisation (WHO) declared the outbreak a Public Health Emergency of International Concern (PHEIC) on 30th January, 2020. Thereafter, it has spread through China and reached the level of a pandemic expanding to 210 countries with 77.9M confirmed cases and 1.71M deaths as per Corona virus Disease (COVID-19) situation report issued by WHO based on data received upto 23rdDecember, 2020. A number of questions remain unanswered regarding pathogen-associated variables for amplification dynamics, host environment and agent interaction. This short communication makes an effort to compile the information gathered from published articles of renowned journals and newsletters to explore the epidemiological characteristics of COVID-19. Hereby in this article, authors have tried to assemble the epidemiological lacunae created by the novel characteristics of the SARS-CoV-2 (Severe Acute Respiratory Syndrome-Corona Virus-2) which presently pose a rather puzzling transmission dynamics of COVID-19 that still remain unanswered.


2020 ◽  
Author(s):  
Fenhua Lai ◽  
Yongtao Zheng ◽  
Hexiang Jia ◽  
Fuliang Wang ◽  
Xiangjue Sun ◽  
...  

Abstract Background: The World Health Organization declared the outbreak a public health emergency of international concern (Corona Virus Disease 2019) on January 30th, this study aimed to investigate the epidemiological and clinical characteristics of Corona Virus Disease 2019 in Xiaoshan, Hangzhou, and evaluate scientific basis for disease control and prevention. Methods: A total of 30 patients had been admitted to hospital from Jan 22 to Feb 22, 2020, all of them were laboratory confirmed SARS-Cov-2. Demographic, epidemiological, clinical, laboratory data were collected from Hospital information system and Epidemiological investigation reports. All data was performed by descriptive analysis, Chi-square test or non-parametric Mann-Whitney U test, as appropriate. Two sided p value less than 0.05 was considered statistically significant.Results: 30 patients were enrolled, the median age was 44.5 years (IQR 33.8-52.3) and 17 (56.7%) patients were female, 14 (46.7%) patients were native and had no exposure to Hubei Province. At the time of study submission, only one patient had not been discharged and no patients died during the study. The median hospital stay was 16.0 days (IQR 12.5-20.5) and the median course of disease was 20.5 days (IQR 17.0-23.3). The most common symptoms were fever (66.7%), dry cough (26.7%), and pharyngalgia (23.3%) on first admission. Most patients were generally illness or more mild, but 10 (33.3%) patients received oxygen therapy and 14 (46.7%) patients received hormone therapy during their hospitalization. Almost half of patients showed mild lymphocytopenia and 40% patients had elevated concentrations of CRP in the early stages of COVID-19.Conclusions: Among the 30 patients were confirmed with SARA-Cov-2 infection in Xiaoshan, Hangzhou, most of them had clinical presentation of respiratory tract infection, but the median course of disease was more than 2 weeks. Further systematic prospective studies about COVID-19 should be urgently needed.


Author(s):  
Mamatha Tittamegalapalya Ramalingaiah ◽  
Jeetendra Kumar Jogihalli Mood ◽  
Vinutha Bagalur Srinivas Murthy ◽  
Virender Singh

Introduction: Corona virus disease is ongoing global pandemic, caused by severe acute respiratory distress syndrome corona virus 2 (SARS-Cov2). The virus was first identified in Wuhan, China in December 2019. The World Health Organization declared the virus a Public Health Emergency of International Concern on 30 January 2020, and later a pandemic on 11 March 2020.The severity of COVID-19 symptoms can range from asymptomatic milder forms to life-threatening. Severe illness is more likely in elderly patients and also in patients with co morbid conditions. Disease can transmit through air contaminated by droplets and small airborne particles. Aims: we aimed to know the clinical profile of covid 19 patients and also to co relate the neutrophil-lymphocyte ratio with clinical outcome of the disease. Materials and methods: This Prospective study was conducted in Patients admitted from August 2020 to October 2020. COVID-19 infection was diagnosed by RT-PCR and rapid antigen test (RAT) technique. Patients demographic data, clinical history was collected. Clinical assessment was performed. Laboratory investigations was sent. Patients were followed during the hospital stay. Appropriate statistical analysis was used Results: Males were commonly affected than females. Mean age of the patient was 61years. Diabetes was the most common co morbid condition. Fever was the most common symptom followed by cough, breathlessness. Neutrophil-lymphocyte ratio was elevated in intubated patients than in patients maintaining room air saturation, which was statistically significant (p value 0.001). Conclusion: Neutrophil-lymphocyte ratio (NLR) can be used as reliable, early marker for the disease progression of covid 19 disease.


Author(s):  
Iman Ahmed Mohammed ◽  
Abbas Hasan Ali ◽  
Jaafer Naseer Al shenaty

Background: the novel coronavirus (2019-ncov), formally known as severe acute respiratory syndrome coronavirus 2 (sars-cov-2), the etiological cause of the (corona virus disease 2019) covid-19, appeared in wuhan, hubei province, china. On 11 march 2020, the world health organization (who) declared this disease as a pandemic. As new information on the clinical characteristics, treatment options, and outcomes for covid-19 emerges approximately every hour, physicians should keep themselves up-to-date on this topic.Objective: to study the demographic features, clinical signs and symptoms and certain vital and laboratory findings of covid-19 hospitalized cases; and to identify the used medication, complications, length of stay at the hospital and disease outcomes of confirmed covid-19 cases.Patients and methods: a descriptive cross-sectional study with analytic elements was conducted at ibn-al khateeb hospital, baghdad on covid-19 patients admitted to the hospital from 1st of march to 4th of may 2020. All inpatients of all age groups, diagnosed as covid-19 and had a definite outcome (recovered and discharge or death) during the period of the study were included.Results: the mean age ± sd for the patients included in the study was = 37.9±18.85 years, with 51.2% being males. The outcome was statistically significantly associated with age, marital status, hypertension, disease severity at admission and length of stay at hospital.Conclusion: this study found that age was associated with disease outcome. Care, attention and monitoring should be taken into consideration for hypertensive patients. Patients’ initial signs and symptoms of dyspnea, weakness and sore throat were significantly associated with disease outcome.


Sign in / Sign up

Export Citation Format

Share Document