scholarly journals Emerging Trends and Research on Hydroxychloroquine Treatment in Diseases From 1991 to 2020

Author(s):  
Lingjun Kong ◽  
Yanan Wang ◽  
Wen Zhang

Abstract Background Recently, hydroxychloroquine (HCQ) has become a controversial point for whether it functioned in the treatment of coronavirus disease 2019 (COVID-19). The aim of this paper is mainly to explore the international frontiers and trends of HCQ clinical treatment in recent 30 years by bibliometric analysis. Besides, the research prospects and hotspots of HCQ therapy in COVID-19 have further been investigated quantitatively and qualitatively. Methods Publications related to HCQ treatment research from 1991 to 2020 and HCQ studies on COVID-19 from the end of 2019 till now were both obtained from Web of Science Core Collection (WOSCC). Bibliometric analyses were primarily performed via Citespace 5.7.R1 to identify the trends of cooperation between countries and institutions, the research hotspots and frontiers. Results A total of 2642 articles and reviews on HCQ treatment in diseases were included, indicating an increase in number of publications since 2013. The United States was the largest scientific output country, followed by France and China. Trending keywords analysis indicated the hotspot research of HCQ treatment referred to “rheumatoid arthriti,” “chloroquine”, “systemic lupus erythematosus” and “COVID-19”. Moreover, 568 publications on the study of HCQ in COVID-19 therapy were also gathered from WOSCC, which showed the USA ranked first again in the world for its most publications. Further, Aix Marseille University, Univ Tehran Med Sci, Univ Paris, Harvard Med Sch and Huazhong Univ Sci & Technol were the five leading institutions in research of HCQ treatment in COVID-19.Conclusion Visualization knowledge map analysis regarding HCQ clinical treatment over the past 30 years suggested scientists are mainly focused on the autoimmune diseases therapy by HCQ. HCQ research have significantly increased since the end of 2019. Obviously, studies on HCQ in COVID-19 may lead the future direction of this field in recent years. The present study provides valuable information on HCQ research through bibliometric analysis so that researchers may identify new perspective and fields.

2021 ◽  
Vol 12 ◽  
Author(s):  
Shijie Zhang ◽  
Hong Fan ◽  
Yonggang Zhang

Background: Citation analysis is a type of quantitative and bibliometric analytic method designed to rank papers based on their citation counts. Over the last few decades, the research on dyslexia has made some progress which helps us to assess this disease, but a citation analysis on dyslexia that reflects these advances is lacking.Methods: A retrospective bibliometric analysis was performed using the Web of Science Core Collection database. The 100 top-cited studies on dyslexia were retrieved after reviewing abstracts or full-texts to May 20th, 2021. Data from the 100 top-cited studies were subsequently extracted and analyzed.Results: The 100 top-cited studies on dyslexia were cited between 245 to 1,456 times, with a median citation count of 345. These studies were published in 50 different journals, with the “Proceedings of the National Academy of Sciences of the United States of America” having published the most (n = 10). The studies were published between 1973 and 2012 and the most prolific year in terms of number of publications was 2000. Eleven countries contributed to the 100 top-cited studies, and nearly 75% articles were either from the USA (n = 53) or United Kingdom (n = 21). Eighteen researchers published at least two different studies of the 100 top-cited list as the first author. Furthermore, 71 studies were published as an original research article, 28 studies were review articles, and one study was published as an editorial material. Finally, “Psychology” was the most frequent study category.Conclusions: This analysis provides a better understanding on dyslexia and may help doctors, researchers, and stakeholders to achieve a more comprehensive understanding of classic studies, new discoveries, and trends regarding this research field, thus promoting ideas for future investigation.


2020 ◽  
pp. 016555152097744
Author(s):  
Binh Pham-Duc ◽  
Trung Tran ◽  
Thao-Phuong-Thi Trinh ◽  
Tien-Trung Nguyen ◽  
Ngoc-Trang Nguyen ◽  
...  

Bibliometric analysis of 3105 publications retrieved from the Scopus database was conducted to evaluate bibliographic content of scientific output on social sciences in Vietnam, for the 2000–2019 period. Our main findings show that the number of publications on social sciences from Vietnam has increased significantly over the last two decades, and there was a spike in the scientific output for the recent three years when the number of publications accounted for 53.76% of the collection. The most productive authors came from a few public research institutes with strong resources as the top 10 institutions participated in 44.22% of the collection. Vietnamese scholars tend not to submit their works to high-ranking journals since five Q1 journals in the top 10 publishing journals published only 6.17% of the collection. For international collaboration, Australia and the United States ranked first and second based on the number of publications and citations. Other countries in top 10 mostly located in Europe and Asia. Research topics were diverse focusing on gender, poverty, HIV, higher education and sustainable development. We suggest that supporting policies and funding need to be provided to help Vietnamese scholars improve their works, and to boost their scientific production in the future.


2020 ◽  
Vol 21 (9) ◽  
pp. 685-703
Author(s):  
Waseem Hassan ◽  
Jean Paul Kamdem ◽  
Mohammad Amjad Kamal ◽  
Joao Batista Teixeira da Rocha

Background: Scopus is regularly covering Current Drug Metabolism from 2000 onwards. Objective: The major objective is to perform the 1st bibliometric analysis of Current Drug Metabolism (CDM). Methods: The data was retrieved from Scopus in April-May 2020 for detail analysis. Results: The total number of publications was found to be 1551, with 955 reviews (61.57%) and 466 articles (30.05%). From 2000 onwards, we calculated the relative growth rate and doubling time. Based on the number of publications, total 4418 authors, 3235 institutions and 83 countries were directly involved in all publications. M.A. Kamal is the highly productive scientist with fifty-three (53 or 3.73%) publications, King Abdulaziz University is the top university with the highest number of publications (58 or 4.13%) and the USA is the top-ranked country with 365 publications (25.96%). We also provided the h-index, total citations (TC), h-index without self-citations (WSC) and total WSC of the top ten authors, universities and countries. In citations analysis, Prof. Zhou S.F. was the top scientist with the highest (1594) number of citations. In institutional category Department of Drug Metabolism, Merck Research Laboratories, Rahway, United States, is the top ranked institutes with 654 total citations. While, United States is the top-ranked country with 18409 total citations. In co-words analysis, 3387, 30564 and 17333 terms in titles of the manuscripts, abstracts and keywords were recorded, respectively. This indicated that CDM principally focused on understanding drug development ranging from its efficacy to delivery, metabolism, distribution, safety and mechanism of actions. Similarly, various specific drugs were thoroughly discussed in publications. Various enzymatic, genetics, proteins and cancer-related aspects were also described. For data presentations, we used VOSviewer graphical maps. Conclusion: The data confirm that CDM showed continuous growth in the number of publications and citations. However significant measures are needed to make overall progress and improve the rankings in relevant categories.


2021 ◽  
Vol 13 (14) ◽  
pp. 7555
Author(s):  
Raghu Raman ◽  
Ricardo Vinuesa ◽  
Prema Nedungadi

India is ranked fifth in the world in terms of COVID-19 publications accounting for 6.7% of the total. About 60% of the COVID-19 publications in the year 2020 are from United States, China, UK, Italy, and India. We present a bibliometric analysis of the publication trends and citation structure along with the identification of major research clusters. By performing network analysis of authors, citations, institutions, keywords, and countries, we explore semantic associations by applying visualization techniques. Our study shows lead taken by the United States, China, UK, Italy, India in COVID-19 research may be attributed to the high prevalence of COVID-19 cases in those countries witnessing the first outbreak and also due to having access to COVID-19 data, access to labs for experimental trials, immediate funding, and overall support from the govt. agencies. A large number of publications and citations from India are due to co-authored publications with countries like the United States, UK, China, and Saudi Arabia. Findings show health sciences have the highest number of publications and citations, while physical sciences and social sciences and humanities counts were low. A large proportion of publications fall into the open-access category. With India as the focus, by comparing three major pandemics—SARS, MERS, COVID-19—from a bibliometrics perspective, we observe much broader involvement of authors from multiple countries for COVID-19 studies when compared to SARS and MERS. Finally, by applying bibliometric indicators, we see an increasing number of sustainable development-related studies from the COVID-19 domain, particularly concerning the topic of good health and well-being. This study allows for a deeper understanding of how the scholarly community from a populous country like India pursued research in the midst of a major pandemic which resulted in the closure of scientific institutions for an extended time.


2021 ◽  
Author(s):  
Jianfei Cao ◽  
Yeongjoo Lim ◽  
Shintaro Sengoku ◽  
Xitong Guo ◽  
Kota Kodama

BACKGROUND Smartphones have become an integral part of our lives with their unprecedented popularity and diversification of applications. The continuous upgrading of information technology has also enabled smartphones to display great potential in the field of healthcare. OBJECTIVE This study aimed to clarify the future research direction of mHealth by analyzing its research trends and latest research hotspots. METHODS This study collected mHealth-related literature published between 2000 and 2020 from the Web of Science database. Descriptive statistics of the literature were computed using Excel software. The publication trends of mHealth research were determined by analyzing the annual number of publications in the literature and annual number of publications categorized based on different countries. Finally, this study used the VOSviewer tool to construct visualization network maps of country/region collaborations and author keyword co-occurrences, and overlay visualization maps of the average publication year of author keywords to analyze the hotspots and research trends in mHealth research. RESULTS In this study, 12,593 mHealth-related research articles published between 2000 and 2020 were collected. The results showed an exponential growth trend in the number of annual publications in mHealth literature. The United States remained the leading contributor to the literature in this area (5,294/12,593, 42%), well ahead of other countries/regions. Other countries/regions also showed a clear trend of annual increases in the number of publications in mHealth literature. Regarding cooperation between countries, the four countries with the largest number of publications, the United States, the United Kingdom, Canada, and Australia, were found to cooperate more closely. The rest of the countries/regions showed a clear geographical pattern of cooperation. The keyword co-occurrence analysis of the top 100 authors formed five clusters, namely: development of mHealth medical technology and its application in various diseases, use of mHealth technology to improve basic public health and health policy, mHealth self-health testing and management in daily life, adolescent use of mHealth, and mHealth in mental health. The research trends revealed a gradual shift in mHealth research from health policy and improving public healthcare to the development and social application of mHealth technologies. CONCLUSIONS To the best of our knowledge, the most current bibliometric analysis dates back to 2016. However, the number of mHealth researches published between 2017 and 2020 exceeds the previous total. Therefore, the results of this study shed light on the latest research hotspots and research trends in mHealth research. These findings provide a useful overview of the development of the field; they may also serve as a valuable reference and provide guidance for other researchers in the field.


2018 ◽  
Vol 22 (8) ◽  
pp. 1655-1687 ◽  
Author(s):  
Magaly Gaviria-Marin ◽  
Jose M. Merigo ◽  
Simona Popa

Purpose In 2017, the Journal of Knowledge Management (JKM) celebrates its 20th anniversary. This study aims to show an updated analysis of their publications to provide a general overview of the journal, focusing on a bibliometric analysis of its publications between 1997 and 2016. Design/methodology/approach The methodology involves two procedures: a performance analysis and a science mapping analysis of JKM. The performance analysis uses a series of bibliometric indicators such as h-index, productivity and citations. This analysis considers different dimensions, including papers, authors, universities and countries. VOSviewer software is used to carry out the mapping of science of JKM, which, based on the concurrence of key words and co-citation points of view, seeks to graphically analyze the structure of the references of this journal. Findings There is a positive evolution in the number of publications (although with certain oscillations), which shows a growing interest in publishing in JKM. The USA and the UK lead the publications in this journal, although at a regional level, Europe is the most productive. The low participation of emerging economies in JKM is also observed. Practical implications The paper will identify the leading trends in the journal in terms of papers, authors, institutions, countries, journals and keywords. This study is useful for obtaining a quick snapshot of what is happening in the journal. Originality/value From the historical record of JKM publications, this study presents an exclusive bibliometric analysis of its publications until 2016 and identifies its main trends.


2021 ◽  
Author(s):  
Keng Yang ◽  
Yekang Hu ◽  
Hanying Qi

BACKGROUND Digital health is growing at a rapid pace, and digital health literacy has tremendous potential to promote health outcomes, bridge the digital divide, and improve health inequalities. OBJECTIVE The purposes of this study are to conduct a systematic bibliometric analysis on the field of dig-ital health literacy and to understand the research context and trends in this field. METHODS A total of 1,955 scientific publications were collected from the Web of Science (WoS) core col-lection. Institutional cooperation, journal co-citation, theme bursting, keyword co-occurrence, author cooperation, author co-citation, literature co-citation and references in the field of digi-tal health literacy were analyzed using the VOSviewer and CiteSpace knowledge mapping tools. RESULTS The results demonstrated that the United States was the leader in number of publications and citations in this field. The University of California System was first in terms of institutional contributions. The Journal of Medical Internet Research led in number of publications, cita-tions and co-citations. Research areas in the field of digital health literacy mainly include the definition and scale of health literacy, health literacy and health outcomes, health literacy and the digital divide, and the influencing factors of health literacy. CONCLUSIONS We summarize research progress in the field of digital health literacy and reveal the context, trends, and trending topics of digital health literacy research through statistical analysis and network visualization. Our work can serve as a fundamental reference and directional guide for future research in this field.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sheng Wang ◽  
Huanping Zhou ◽  
Li Zheng ◽  
Wanli Zhu ◽  
Lina Zhu ◽  
...  

Acute lung injury (ALI) is an intractable disorder associated with macrophages. This bibliometric analysis was applied to identify the characteristics of global scientific output, the hotspots, and frontiers about macrophages in ALI over the past 10 years. We retrieved publications published from 2011 to 2020 and their recorded information from Science Citation Index Expanded (SCI-expanded) of Web of Science Core Collection (WoSCC). Bibliometrix package was used to analyze bibliometric indicators, and the VOSviewer was used to visualize the trend and hotspots of researches on macrophages in ALI. Altogether, 2,632 original articles were reviewed, and the results showed that the annual number of publications (Np) concerning the role of macrophages in ALI kept increasing over the past 10 years. China produced the most papers, the number of citations (Nc) and H-index of the USA ranked first. Shanghai Jiaotong University and INT IMMUNOPHARMACOL were the most prolific affiliation and journal, respectively. Papers published by Matute-Bello G in 2011 had the highest local citation score (LCS). Recently, the keywords “NLRP3” and “extracellular vesicles” appeared most frequently. Besides, researches on COVID-19–induced ALI related to macrophages seemed to be the hotspot recently. This bibliometric study revealed that publications related to macrophages in ALI tend to increase continuously. China was a big producer and the USA was an influential country in this field. Most studies were mainly centered on basic researches in the past decade, and pathways associated with the regulatory role of macrophages in inhibiting and attenuating ALI have become the focus of attention in more recent studies. What is more, our bibliometric analysis showed that macrophages play an important role in COVID-19–induced ALI and may be a target for the treatment of COVID-19.


Author(s):  
Jen Ling Gan ◽  
Aqilah Yaacob

Objective: There is limited literature that discussed the trend of ‘employee voice’. Hence, this bibliometric analysis is aimed to evaluate the global research growth to retrieve and analyze the publication on ‘employee voice’. The bibliometric analysis is used to search the database of Scopus from the oldest publication in 1986 to the recent publication in 2019. The objectives were to evaluate the trend of ‘employee voice’ research, details of co-authorship, leading institutions and countries, top scholars, and leading author keywords. Methodology: This study used VOS Viewer 1.6.11 to analyze and visualize the global research trend on ‘employee voice’ in analyzing the bibliographic data. Bibliometric maps were retrieved from VOS Viewer 1.6.11. Results: This study retrieved 443 journal articles from the Scopus database from 1986 to 2019. The publication’s trend revealed that the number of publications has been increasing steadily since 2005. The leading countries in ‘employee voice’ research are the United Kingdom and the United States. Among the fifteen leading universities, five of them were from the world’s top 150 universities. Among the keywords, ‘voice behavior’ has the most linkage with ‘employee voice’, which indicated that employee voice is active in the business and management field compared to other fields such as nursing and psychology. According to the author keywords analysis, ‘promotive voice’ and ‘prohibitive voice’ were found to become a potential concerned area in the future as they started to receive attention in 2017. Implication: This paper can be beneficial for academicians, organizations, and business policymakers in understanding the global trend of ‘employee voice’ besides discovering the future directions and opportunities for future studies.


2021 ◽  
Vol 11 ◽  
Author(s):  
Haoran Ding ◽  
Chenzhou Wu ◽  
Nailin Liao ◽  
Qi Zhan ◽  
Weize Sun ◽  
...  

ObjectivesTo date, radiomics has been applied in oncology for over a decade and has shown great progress. We used a bibliometric analysis to analyze the publications of radiomics in oncology to clearly illustrate the current situation and future trends and encourage more researchers to participate in radiomics research in oncology.MethodsPublications for radiomics in oncology were downloaded from the Web of Science Core Collection (WoSCC). WoSCC data were collected, and CiteSpace was used for a bibliometric analysis of countries, institutions, journals, authors, keywords, and references pertaining to this field. The state of research and areas of focus were analyzed through burst detection.ResultsA total of 7,199 pieces of literature concerning radiomics in oncology were analyzed on CiteSpace. The number of publications has undergone rapid growth and continues to increase. The USA and Chinese Academy of Sciences are found to be the most prolific country and institution, respectively. In terms of journals and co-cited journals, Scientific Reports is ranked highest with respect to the number of publications, and Radiology is ranked highest among co-cited journals. Moreover, Jie Tian has published the most publications, and Phillipe Lambin is the most cited author. A paper published by Gillies et al. presents the highest citation counts. Artificial intelligence (AI), segmentation methods, and the use of radiomics for classification and diagnosis in oncology are major areas of focus in this field. Test-retest statistics, including reproducibility and statistical methods of radiomics research, the relation between genomics and radiomics, and applications of radiomics to sarcoma and intensity-modulated radiotherapy, are frontier areas of this field.ConclusionTo our knowledge, this is the first study to provide an overview of the literature related to radiomics in oncology and may inspire researchers from multiple disciplines to engage in radiomics-related research.


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