Could anterior cervical fixation be an alternative method in the management of Hirayama disease?

2021 ◽  
Author(s):  
Wence Wu ◽  
Zhechen Li ◽  
Hongjie Zhang ◽  
Renqin Lin ◽  
Jianhua Lin
Keyword(s):  
Clinical Efficacy ◽  
The Other ◽  
Time Range ◽  
Site Infection ◽  
Cervical Lordosis ◽  
Screw Loosening ◽  
Internal Fixators ◽  
Cross Sectional ◽  
Hirayama Disease ◽  
Loss Range

Abstract The study aimed to evaluate the clinical efficacy and feasibility of surgical treatment for Hirayama disease(HD) by anterior cervical fixation(ACF). From August 2008 to November 2015, 13 patients(12 males and 1 female, average age, 16.3 ± 1.1 years) with HD underwent ACF. Surgery-related indexes, clinical efficacy, and radiographic parameters were used to evaluate the clinical outcomes of surgery. The surgery duration time range from 67 to 128 min(average 89.2 ± 19.9 min)and the blood loss range from 40 to 120 ml(average 68.1 ± 26.3 ml). Four patients got resolved tremor, and the other patients stopped progressing. Grip strength significantly improved from preoperative 15.6 ± 1.7 kilogram to postoperative 18.6 ± 1.9 kilogram(P < 0.001). The cross-sectional areas of the spinal cord at C6 and C7 levels increased from 0.7 ± 0.1 cm2 to 0.8 ± 0.1 cm2(P = 0.018) and from 0.6 ± 0.2 cm2 to 0.7 ± 0.1 cm2(P = 0.049) respectively. The cervical lordosis increased from 2.4 ± 3.4° to 7.0 ± 3.5°(P = 0.001). The range of cervical flexion was significantly decreased from preoperative 31.3 ± 11.5° to postoperative 14.3 ± 7.5°(P < 0.001). No surgical related complications such as hoarseness, cerebral fluid leakage, and surgical site infection were observed after surgery. Two patients, felt abnormal sensation of throat occasionally, showed screw loosening and internal fixators were removed finally. Athough screw loosening was observed, ACF could serve as an effective treatment in the management of the HD.

HISTOPATHOLOGY OF THE PIGMENTED TUMORAL-LIKE LESIONS OF THE SKIN AT HUE HOSPITAL OF MEDICINE AND PHARMACY UNIVERSITY

2018 ◽  
Vol 8 (4) ◽  
pp. 65-69
Author(s):  
Mao Nguyen Van ◽  
Dong Tran Nam
Keyword(s):  
Key Words ◽  
Definitive Diagnosis ◽  
The Other ◽  
Cell Tumour ◽  
Cross Sectional ◽  
Skin Tumour ◽  
Clinical Appearance ◽  
The Face ◽  
The Common ◽  
Difficult Cases

Background: Pigmented tumour of the skin is one of the common tumour in human including the benign pigmented tumours (more common) called Nevi tumours and the malignant one called melanoma which was less frequent but the most poor in prognosis. In addition, the others not belonging to these group had the same clinical appearance, so the application of histopathology and immunohistochemistry for the definitive diagnosis was indespensible. Objectives: 1. To describe the macroscopic features of the pigmented tumoral-like lesions; 2. To classify the histopathologic types of the pigmented cell tumours and the other pigmented tumours of the skin. Materials and Method: Cross-sectional research on 55 patients diagnosed as pigmented tumoral lesions by clinician, then all definitively diagnosed by histopathology combining the immunohistochemistry in difficult cases. Results: There was no difference in gender, the disease was discovered most common in adult, especially with the age over 51 years old (58.1%). the most region located was in the face accounting for 60%, following the trunk and limbs (14.6%, 12.8% respectively). All 3 malignant melanomas happened in foot. The most common color of the lesions was black (65.4%), the other ones were rose, grey and blue. Histopathology and immunohisthochemistry showed that the true pigmented cell tumours were 52.6% encompassing benign ones (Nevi tumour) (41.8%), melanoma (5.4%) and lentigo (5.4%). 47.4% was not the true pigmented cell tumour including pigmented basocellular carcinoma (36.4%) and the others less common as histiofibromas, acanthoma and papilloma. Conclusion: the pigmented tumoral-like lesions of the skin could be the true pigmented cell tumours and the others, so the application of the histopathology and the immunohistochemistry after the clinical discovery helps to determine and classify the disease definitely and for the best orientation of treatment as well. Key words: skin tumour, benign pigmented tumour (Nevi), malignant pigmented tumour (melanoma), pigmented basocellular carcinoma

EXPRESSION OF SOME IMMUNOLOGIC MARKERS FOR THE DIAGNOSIS OF SUSPECTED LYMPHOID LESIONS OF LYMPHOMA

2018 ◽  
Vol 8 (4) ◽  
pp. 28-33
Author(s):  
Mao Nguyen Van ◽  
Thao Le Thi Thu
Keyword(s):  
Correct Diagnosis ◽  
Tumour Cells ◽  
The Body ◽  
The Other ◽  
Cervical Region ◽  
Cross Sectional ◽  
Immunologic Markers ◽  
Microscopic Features ◽  
Poor Differentiation ◽  
Benign Tumours

Background: In practice it was difficult or impossible to have a correct diagnosis for the lymphoid proliferation lesions based on only H.E standard histopathology. In addition to histopathology, the application of immunohistochemistry was indispensable for the definitive diagnosis of the malignant or benign tumours and the origin of the tumour cells as well. Objectives: 1. To describe the gross and microscopic features of the suspected lesions of lymphoma; 2. To asses the expression of some immunologic markers for the diagnosis and classification of the suspected lesions of lymphoma. Materials and Method: Cross-sectional research on 81 patients diagnosed by histopathology as lymphomas or suspected lesions of lymphoma, following with immunohistopathology staining of 6 main markers including LCA, CD3, CD20, Bcl2, CD30 and AE1/3. Results: The most site was lymph node 58.1% which appeared at cervical region 72.3%, then the stomach 14.9% and small intestine 12.4%. The other sites in the body were met with lower frequency. Histopathologically, the most type of the lesions was atypical hyperplasia of the lymphoid tissue suspecting the lymphomas 49.4%, lymphomas 34.5%, the other diagnoses were lower including inflammation, poor differentiation carcinoam not excluding the lymphomas, lymphomas differentiating with poor differentiation carcinomas. Immunohistochemistry showed that, LCA, CD3, CD20, Bcl2, CD30 and AE1/3 were all positive depending on such type of tumours. The real lymphomas were 48/81 cases (59.3%), benign ones 35.8% and poor differentiated carcinomas 4.9%. Conclusion: Immunohistochemistry with 6 markers could help to diagnose correctly as benign or malignant lesions, classify and determine the origin of the tumour cells as lymphocytes or epithelial cells diagnosed by histopathology as lymphomas or suspected lesions of lymphomas. Key words: histopathology, immunohistochemistry, lymphomas, poor differentiated carcinomas, hyperplasia, atypicality

HOSPITAL INFECTION IN SURGICAL DEPARTMENTS AT HUE UNIVERSITY HOSPITAL IN 2015

2016 ◽  
pp. 39-43
Author(s):  
Dinh Binh Tran ◽  
Dinh Tan Tran
Keyword(s):  
Surgical Site Infection ◽  
Surgical Intervention ◽  
University Hospital ◽  
Hospital Infections ◽  
Site Infection ◽  
Cross Sectional ◽  
Surgical Interventions ◽  
Hospital Acquired Infections ◽  
Tract Infections ◽  
Hospital Acquired

Objective: To study nosocomial infections and identify the main agents causing hospital infections at Hue University Hospital. Subjects and Methods: A cross-sectional descriptive study of 385 patients with surgical interventions. Results: The prevalence of hospital infections was 5.2%, surgical site infection was the most common (60%), followed by skin and soft tissue infections (35%), urinary tract infections (5%). Surgical site infection (11.6%) in dirty surgery. There were 3 bacterial pathogens isolated, including Staphylococcus aureus (50%), Pseudomonas aeruginosa and Enterococcusspp (25%). Conclusion: Surgical site infection was high in hospital-acquired infections. Key words: hospital infections, surgical intervention, surgical site infection, bacteria

Human density, economic level and frequency of canine helminths in Buenos Aires

2021 ◽  
Vol 95 ◽  
Author(s):  
D. Rubel ◽  
N. Flaibani
Keyword(s):  
Linear Models ◽  
Buenos Aires ◽  
Toxocara Canis ◽  
The Other ◽  
Green Spaces ◽  
Cross Sectional ◽  
Independent Variables ◽  
Economic Level ◽  
Faecal Samples ◽  
Human Density

Abstract The aim of this study was to explore through cross-sectional study the variation in the prevalence of parasitic helminths in canine faeces collected from green spaces of Buenos Aires according to the human density (HD) and economic level (EL) in the surroundings. HD and EL were considered as independent variables with three categories each. Twenty public squares (one hectare of surface) were randomly selected for each existing combination of the two independent variables. Ten random samples of fresh canine faeces were obtained in each square and analysed for helminths by the sedimentation and flotation techniques. The prevalence for each of the species was analysed using generalized linear models (GLM). The prevalence was modelled with a binomial error distribution and a logit link function. Helminth eggs were detected in 45 out of the 200 (22.5%) faecal samples collected and in 18 of the 20 green spaces sampled. The species observed were Ancylostoma caninum (13% of samples), Trichuris vulpis (8%) and Toxocara canis (4.5%). The GLM indicated that the prevalence of A. caninum in the slum areas (very high HD and very low EL) was higher than that in the other areas studied. However, the HD seemed to contribute more than the EL to the variations in the prevalence of A. caninum in faecal samples. The GLM showed no differences in the prevalence of the other parasite species for the different levels of the independent variables.

scholarly journals Quality of Life of Brazilian Vegetarians Measured by the WHOQOL-BREF: Influence of Type of Diet, Motivation and Sociodemographic Data

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2648
Author(s):  
Shila Minari Hargreaves ◽  
Eduardo Yoshio Nakano ◽  
Heesup Han ◽  
António Raposo ◽  
Antonio Ariza-Montes ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Online Survey ◽  
Well Being ◽  
Vegetarian Diet ◽  
The Other ◽  
Average Score ◽  
Cross Sectional ◽  
Domain 3 ◽  
Domain 4

This study aimed to evaluate the general quality of life (QoL) of Brazilian vegetarians. A cross-sectional study was conducted with Brazilian vegetarian adults (18 years old and above). Individuals were recruited to participate in a nationwide online survey that comprised the WHOQOL-BREF as well as sociodemographic and characterization questions related to vegetarianism. The WHOQOL-BREF is composed of 24 items which are divided into four domains (domain 1: physical health; domain 2: psychological well-being; domain 3: social relationships; and domain 4: environment), plus two general items which were analyzed separately, totaling 26 items. The answers from the questionnaire were converted into scores with a 0–100 scale range, with separate analyses for each domain. Results were compared among groups based on the different characteristics of the vegetarian population. A total of 4375 individuals completed the survey. General average score results were 74.67 (domain 1), 66.71 (domain 2), 63.66 (domain 3) and 65.76 (domain 4). Vegans showed better scores when compared to the other vegetarians, except in domain four, where the statistical difference was observed only for semi-vegetarians (lower score). Individuals adopting a vegetarian diet for longer (>1 year) showed better results for domains one and two, with no difference for the other domains. Having close people also adopting a vegetarian diet positively influenced the results for all domains. On the other hand, it was not possible to distinguish any clear influence of the motivation for adopting a vegetarian diet on the scores’ results. Adopting a vegetarian diet does not have detrimental effects on one’s QoL. In fact, the more plant-based the diet, and the longer it was adopted, the better the results were.

scholarly journals Perceived discrimination and psychological distress among immigrants to Canada: The mediating role of bicultural identity orientations

2021 ◽  
pp. 136843022199008
Author(s):  
Mustafa Firat ◽  
Kimberly A. Noels
Keyword(s):  
Psychological Distress ◽  
Undergraduate Students ◽  
Structural Equation ◽  
Perceived Discrimination ◽  
The Other ◽  
Equation Modeling ◽  
Bicultural Identity ◽  
Cross Sectional ◽  
Mediating Role ◽  
The Relationship

Bicultural identity orientations have rarely been examined in relation to both perceived discrimination and psychological distress. Furthermore, these constructs have usually been studied in isolation, but their intersection is essential for understanding intercultural relations in multicultural societies. Using cross-sectional data from 1,143 Canadian undergraduate students from immigrant families, this study explored the relationship between perceived discrimination and psychological distress, and how bicultural identity orientations might mediate this relationship. The structural equation modeling results indicated that perceived discrimination was associated with higher levels of psychological distress and hybrid, monocultural, alternating, and conflicted orientations, but lower levels of complementary orientation. Alternating and conflicted orientations were related to higher psychological distress, whereas the other orientations were not. Alternating and conflicted orientations mediated the relationship between perceived discrimination and psychological distress, whereas the other orientations did not. The findings are discussed in light of theories on identity integration, rejection–identification, and acculturation.

Stock Price Jumps and Cross-Sectional Return Predictability

2013 ◽  
Vol 48 (5) ◽  
pp. 1519-1544 ◽  
Author(s):  
George J. Jiang ◽  
Tong Yao
Keyword(s):  
Stock Prices ◽  
Stock Price ◽  
Stock Return ◽  
Return Predictability ◽  
Value Premium ◽  
The Other ◽  
Stock Return Predictability ◽  
Cross Sectional ◽  
Return Dynamics

AbstractWe identify large discontinuous changes, known as jumps, in daily stock prices and explore the role of jumps in cross-sectional stock return predictability. Our results show that small and illiquid stocks have higher jump returns to the extent that cross-sectional differences in jumps fully account for the size and illiquidity effects. Based on value-weighted portfolios, jumps also account for the value premium. On the other hand, jumps are not the cause of momentum or net share issue effects. The findings of our study shed new light on stock return dynamics and present challenges to conventional explanations of stock return predictability.

Abstract 1122‐000172: High Resolution Vessel Wall Imaging and Cerebrovascular Plaques: Comparison with DSA, MRA, and CTA

2021 ◽  
Vol 1 (S1) ◽  
Author(s):  
Rami Fakih ◽  
Alberto Miller ◽  
Ashrita Raghuram ◽  
Sebastian Herrera ◽  
Sedat Kandemirli ◽  
...  
Keyword(s):  
Vessel Wall ◽  
The Other ◽  
Imaging Modalities ◽  
Plaque Burden ◽  
Rater Agreement ◽  
Cross Sectional ◽  
Tof Mra ◽  
Plaque Detection ◽  
Wall Imaging

Introduction : Current imaging modalities might underestimate the presence and severity of intracranial atherosclerosis (ICAD). High resolution vessel wall imaging (HR‐VWI) MRI emerged as a powerful tool to diagnose plaques not detected on routine imaging. We aim to compare different imaging modalities (HR‐VWI MRI; digital subtraction angiogram (DSA); Time‐of‐flight (TOF) MRA; and CTA) in the identification and characterization of intracranial atherosclerotic culprit plaques. Methods : Patients diagnosed with ICAD were prospectively imaged with HR‐VWI MRI. Culprit plaques were identified based on the likelihood of causing the stroke. Using cross‐sectional images of intracranial vessels, regions of interest (ROI) were delineated. Then, diameters and ROI areas were measured for the purpose of calculating the following variables: degree of stenosis (DS) at the plaque level, plaque burden (PB), and remodeling index (RI). Additional imaging modalities (DSA, TOF MRA, and CTA) were identified retrospectively for each patient. The sensitivity of detecting a culprit plaque as well as the correlations between the different variables were analyzed for each modality. Linear regression analysis was used to determine the association of DS with PB and RI. Interobserver agreement on the determination of a culprit plaque on every imaging modality was evaluated. Results : A total of 44 patients who underwent HR‐VWI had ICAD and were included in the final analysis. Of those, 34 had CTA, 18 had TOF‐MRA, and 18 had DSA. Using HR‐VWI as gold standard, the sensitivity for culprit plaque detection was 88% for DSA, 78% for TOF MRA, and 76% for CTA. We found no difference between the DS in all four modalities using measured cross‐sectional diameters, but difference was found when measuring ROI areas to calculate DS. There was a significant positive correlation between PB and DS on HR‐VWI MRI (p<0.001), but not on the DSA (p = 0.168), MRA (p = 0.144), or CTA (p = 0.253), and a significant negative correlation between RI and DS on HR‐VWI MRI (p = 0.003), but not on DSA (p = 0.783), MRA (p = 0.405), or CTA (p = 0.751). PB and RI predicted the degrees of stenosis on HR‐VWI, but not on the other modalities. There was good inter‐rater agreement for culprit plaque detection on HR‐VWI (k = 0.48, p = 0.001), but no agreement was found on the other modalities. Conclusions : HR‐VWI MRI can locate otherwise undetectable plaques on conventional imaging through the ability to measure plaque burden, an essential component for characterization of plaques severity and a strong predictor of stenosis. HR‐VWI also showed more accurate measurements of degree of stenosis through measurement of ROI areas, and had good inter‐rater agreement for accurate plaque detection, compared to DSA, MRA, and CTA.

scholarly journals Hypermobility and sports injury

2018 ◽  
Vol 4 (1) ◽  
pp. e000366 ◽  
Author(s):  
Joseph Alexander Nathan ◽  
Kevin Davies ◽  
Ian Swaine
Keyword(s):  
Statistical Analysis ◽  
Sports Injury ◽  
The Other ◽  
Anecdotal Evidence ◽  
Demographic Information ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Exact Test ◽  
Joint Dislocation ◽  
Ligament Sprain

ObjectiveTo determine whether there is an association between hypermobility and sports injury.MethodsA quantitative observational approach using a cross-sectional survey was adopted. Individuals were identified as hypermobile or not. All participants were asked to complete two questionnaires: one asking demographic information and the other injury-specific. Fisher’s exact test was used for statistical analysis.Results114 individuals participated in the study, 62 women and 52 men. 26% of the participants were hypermobile. There was no significant association between hypermobility and sports injury (p=0.66). There was a significant increase in joint and ligament sprain among the non-hypermobile (NH) group covering all sports (p=0.03). Joint dislocation was found exclusively among hypermobile individuals. The duration of injury in hypermobile individuals was higher than NH. The use of oral painkillers or anti-inflammatories in the semiprofessional group was greater than the general population.ConclusionHypermobility is relatively common among individuals, and there is a lot of anecdotal evidence associating it with increased rates of injuries. This project finds that NH individuals are more likely to sustain a ligament or joint sprain in sports. This is due to increased joint laxity and flexibility preventing injury. There were important limitations to this study which will be addressed in further work. These include assessing for pauciarticular hypermobility and focusing on one sport to investigate its association with sports injury in those who are hypermobile or not. It would also be important to focus on one specific joint, assessing its flexibility and association with injury.

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