Spontaneous Reporting of Adverse Drug Reaction Among Health Professionals In Kpone-Katamanso District, Ghana

Author(s):  
Morrison Asiamah ◽  
Kwadwo Owusu Akuffo ◽  
Pricillia Nortey ◽  
Nina Donkor ◽  
Anthony Danso-Appiah

Abstract Background: Spontaneous reporting of adverse drug reactions (ADR) is an effective means of ensuring postmarketing surveillance of drugs, and health professionals play a cardinal role through voluntary reporting of ADR. However, the pharmacovigilance system in Ghana is plagued with under-reporting issues, which is of public health concern. Method: A questionnaire-based cross-sectional study involving 268 health professionals at Kpone-Katamanso District was carried out. Data on spontaneous reporting of ADR, demographics of participants, knowledge, and attitudes of professionals towards reporting and factors that may influence ADR reporting were collected. Logistic regression models were used to examine the association of the independent variables with spontaneous reporting of ADR.Result: Overall, 77.6% (208) of the 268 respondents had witnessed ADR; however, only 17.3% of the respondents have ever reported an ADR to the FDA. Health professionals who had adequate knowledge on spontaneous reporting of ADR were 51.9%, while 30.3% had very good knowledge of spontaneous reporting of ADR. After statistical adjustment, Age (AOR=2.26, 95%CI= 1.25–4.10), Fear of Legal Consequences (AOR=0.15, 95%CI=0.41–0.51), Time Constraint (AOR=0.3, 95%CI=0.10–0.91), Pharmacovigilance training (AOR= 18.78, 95%CI= 5.46–64.59) and Unavailability of Reporting form (AOR=0.28, 95%CI=0.09– 0.88) were found to be significantly associated spontaneous reporting of ADR. Conclusion: The proportion of health professionals in the Kpone-Katamanso District who spontaneously report observed ADR is low. Our findings underscore the need for the FDA to intensify awareness through media sensitization and engage all relevant stakeholders on the need for the entire population to report ADR.

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Joana Seringa ◽  
Ana Patrícia Marques ◽  
Bruno Moita ◽  
Cátia Gaspar ◽  
João Filipe Raposo ◽  
...  

Abstract Background Multiple admissions for ambulatory care sensitive conditions (ACSC) are responsible for an important proportion of health care expenditures. Diabetes is one of the conditions consensually classified as an ACSC being considered a major public health concern. The aim of this study was to analyse the impact of diabetes on the occurrence of multiple admissions for ACSC. Methods We analysed inpatient data of all public Portuguese NHS hospitals from 2013 to 2015 on multiple admissions for ACSC among adults aged 18 or older. Multiple ACSC users were identified if they had two or more admissions for any ACSC during the period of analysis. Two logistic regression models were computed. A baseline model where a logistic regression was performed to assess the association between multiple admissions and the presence of diabetes, adjusting for age and sex. A full model to test if diabetes had no constant association with multiple admissions by any ACSC across age groups. Results Among 301,334 ACSC admissions, 144,209 (47.9%) were classified as multiple admissions and from those, 59,436 had diabetes diagnosis, which corresponded to 23,692 patients. Patients with diabetes were 1.49 times (p < 0,001) more likely to be admitted multiple times for any ACSC than patients without diabetes. Younger adults with diabetes (18–39 years old) were more likely to become multiple users. Conclusion Diabetes increases the risk of multiple admissions for ACSC, especially in younger adults. Diabetes presence is associated with a higher resource utilization, which highlights the need for the implementation of adequate management of chronic diseases policies.


Author(s):  
A. H. M. Shamim Al Mamun ◽  
Kamrul Hsan ◽  
Md. Shanjid Sarwar ◽  
Md. Ruhul Furkan Siddique

Background: Millions of people are suffering from food borne illness and it has become a growing public health concern in the world. To reduce the burden of food borne illness, food handlers must have accurate knowledge of food safety. The objective of the study was to assess the knowledge and level of personal hygiene practice among food handlers of Jahangirnagar University.Methods: It was a descriptive cross sectional study, done among the food handlers in Jahangirngar University Campus, Dhaka, Bangladesh from May 2016 to September 2016. Data were collected from 119 food handlers by using face to face interview using a pre-tested questionnaire. Statistical Package for Social Sciences (SPSS 22.0) software was used for data analysis.Results: Study found that 65.55% of the food handlers did not have adequate knowledge regarding personal hygiene. The study also found that 71.4% of the food handlers had poor hygiene practice. The study revealed that age, education and sleeping place and knowledge regarding personal hygiene were significantly associated with the respondent’s personal hygiene practice.Conclusions: The study shows that knowledge and its practice among the food handlers is very poor. Implementation of training and awareness program on personal hygiene are required to improve their knowledge and personal hygiene practice.


2020 ◽  
Author(s):  
Helene Carrier ◽  
Anna Zaytseva ◽  
Aurélie Bocquier ◽  
Patrick Villani ◽  
Martin Fortin ◽  
...  

Abstract Background. Cooperation between general practitioners (GPs) and other health professionals appears to help reduce the risk of adverse events linked to polypharmacy for patients with multimorbidity. We investigated the existence of different GP profiles according to their opinions and behaviors about such cooperation and studied the association between these profiles and the GPs’ characteristics and deprescribing behaviors.Methods. Between May and July 2016, we performed a cross-sectional survey in a panel of French GPsabout their management of patients with multimorbidity and polypharmacy, focusing specifically on their opinions of healthcare professionals’ roles and interprofessional cooperation. We used an agglomerative hierarchical cluster analysis to identify GP profiles and then multivariable logistic regression models to study their associations with these doctors' characteristics and deprescribing behaviors.Results. We identified four profiles of GPs according to their cooperation propensities: GPs from the “intensive” profile (14%) were favorable to cooperating with various health professionals, including delegating some prescribing tasks to pharmacists; GPs from the "moderate" profile (47%) had favorable opinions about health professionals’ roles, except for this specific task delegation; GPs from the "selective" profile (27%) tended to work only with physicians; GPs from the "low cooperation" profile (12%) didn’t appeared interested in cooperation. These profiles were associated with different professional characteristics.Conclusions. Current health policies encourage interprofessional cooperation for the management of patients with multimorbidity. Our study provides information for understanding disparities among GPs regarding working with other professionals who deal with their patients and suggests possible ways to improve cooperation.


Author(s):  
Asifa Ashraf ◽  
Ipseeta Menon ◽  
Ritu Gupta ◽  
Vikram Arora ◽  
Dipshikha Das ◽  
...  

Background and Objectives: Covid-19 is highly contagious disease and has today become a major public health concern in the developing countries worldwide. This study attempted to assess the knowledge, attitude, anxiety experience, perceived mental healthcare, and oral health among adult Kashmiri population during the COVID-19 pandemic. Methods: An anonymous online questionnaire was developed using Google forms to avoid person-to-person contact. The structured questionnaire consisted of questions covering several areas: sociodemographic data, knowledge, awareness, attitude about the COVID-19 , the anxiety level, oral hygiene habits during confinement, care and disinfection control behaviours in the dental environment. Results: Due to continuing conflict in Kashmir during the last 18 years there has been a phenomenal increase in psychiatric morbidity. The results reveal that the prevalence of depression was high 46.3% among Kashmiri residents who were anxious with the thought of  COVID-19 virus. In our study it was also found that 66.2% of the responders had a moderate level of knowledge about being getting quarantined and 97.7% of the participants had an adequate knowledge about its preventive aspects. The anxiety levels identified in the study were high i.e. more than 70% of the participants were preoccupied with the COVID-19 pandemic over the past months. Approximately, 42.6% of the participants have been angered and distressed due to being worried about the ongoing pandemic. Oral hygiene and last visit to the dentist were found highly significant in our study i.e. approximately  36.6% of the participants had visited a dentist among which 35.2% had visited only due to consultation advise. Conclusion: Population of Kashmir had a better mean knowledge score regarding this virus but yet mental health is an integral part of overall health and quality of life. Substantial and sustainable improvements can be achieved only when a comprehensive strategy for mental health which incorporates both prevention and care elements is adopted. There is a need to intensify the awareness and address the mental health issues, and importance of oral hygiene of people during this COVID-19 pandemic.


2020 ◽  
Vol 17 (2) ◽  
pp. 1-22
Author(s):  
Beatriz Edra ◽  
Bruno Magalhães ◽  
Mafalda Silva ◽  
Maria do Céu Costa

The nature, diversity, and hazardousness of hospital waste (HW) require specific management procedures. Specific interventions on HW are imperative for modern societies, imposed by public and environmental health policies. The health institutions strategic management plan integrates HW management policies considering a social technic perspective process in their institutional strategic management plan, taking into account a sociotechnical perspective, based on related good practices. Sorting is one of the most critical phases for effective management in reducing risks of generated hospital waste, more specifically at the generation site. Health professionals play an important role in this process since they participate in sorting in different contexts of clinical practice. This research aimed to identify the periodicity of contact of different health professionals such as nurses, doctors and medical assistants (MA) with HW, and their knowledge regarding the practices of sorting and storing of HW. An observational, descriptive, and correlational cross-sectional study was developed. Data were gathered through a questionnaire applied to a sample of 1800 health professionals recruited from a Hospital Center in Porto ( Portugal). Results showed that from the 79% of health professionals who were in contact with HW, 68.7% had adequate knowledge about sorting practices. Health professionals presented more doubts in sorting and storing wastes from Groups III (Biological Hazard HW) and IV (HW of obligatory incineration).


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Babar Irfan ◽  
Ibrahim Zahid ◽  
Muhammad Sharjeel Khan ◽  
Omar Abdul Aziz Khan ◽  
Shayan Zaidi ◽  
...  

Abstract Background Basic Life Support (BLS) is the recognition of sudden cardiac arrest and activation of the emergency response system, followed by resuscitation, and rapid defibrillation. According to WHO, Pakistan has one of the highest mortality rates from accidental deaths therefore assessment and comparison of BLS knowledge in health professionals is crucial. We thereby aim to assess and compare the knowledge of BLS in doctors, dentists and nurses. Methods A multi-centric cross-sectional survey was conducted in Karachi at different institutions belonging to the private as well as government sector from January to March 2018. We used a structured questionnaire which was adapted from pretested questionnaires that have been used previously in similar studies. Descriptive statistics were analyzed using SPSS v22.0, where adequate knowledge was taken as a score of at least 50%. P < 0.05 was considered as significant. Logistic regression was used to identify the factors affecting the knowledge regarding BLS in health care professionals. Results The responders consisted of 140 doctors, nurses and dentists each. Only one individual (dentist) received a full score of 100%. In total, 58.3% of the population had inadequate knowledge. Average scores of doctors, dentists and nurses were 53.5, 43.3 and 38.4% respectively. Doctors, participants with prior training in BLS and those with 6 to 10 years after graduation were found to be a significant predictor of adequate knowledge, on multivariate analysis. Conclusion Even though knowledge of BLS in doctors is better than that of dentists and nurses, overall knowledge of health care professionals is extremely poor. Present study highlights the need for a structured training of BLS for health care workers.


2020 ◽  
Vol 42 (3) ◽  
pp. 493-503 ◽  
Author(s):  
Bada Sharanappa Nagaraja ◽  
Kalhalli Narayanaswamy Ramesh ◽  
Debjyoti Dhar ◽  
Mahammad Samim Mondal ◽  
Treshita Dey ◽  
...  

Abstract Background The rising burden of Coronavirus disease (COVID-19) has led to the mass use of hydroxychloroquine by healthcare workers (HCWs). Adverse event profile of this drug when used as prophylaxis is not well known in the literature. Methods A retrospective, cross-sectional study was conducted across the country using semi-structured web-based questionnaire among COVID-19 negative and asymptomatic healthcare workers, taking hydroxychloroquine prophylaxis. Descriptive and multivariate logistic-regression models were applied for analysis. Results Of the 166 participants, at least one adverse event was experienced by 37.9% participants, gastrointestinal being the most common (30.7%). Risk was higher in participants &lt;40 years age (odd’s ratio (OR): 2.44, 95% confidence interval (CI): 1.18–5.05) and after first dose of hydroxychloroquine (51.2%, OR: 2.38, 95%CI: 1.17–4.84). Hydroxychloroquine prophylaxis was initiated without electrocardiography by 80.1% of HCWs. Only 21.6% of those with cardiovascular disease could get prior ECG. Conclusions A higher incidence of adverse events was observed when results were compared with studies involving patients on long-term hydroxychloroquine therapy. Younger age and first dose were associated with greater incidence of adverse events though all were self-limiting. Monitoring prior and during prophylaxis was inadequate even among those with cardiovascular disease and risk-factors. However, no serious cardiovascular events were reported.


2017 ◽  
Vol 20 (9) ◽  
pp. 1609-1616 ◽  
Author(s):  
Alyson Haslam ◽  
Sara Wagner Robb ◽  
James R Hébert ◽  
Hanwen Huang ◽  
Michael D Wirth ◽  
...  

AbstractObjectiveThe Dietary Inflammatory Index (DII)TM, which was developed to characterize the inflammatory potential of a person’s diet, has been shown to be associated with inflammatory conditions such as cancer. The present study aimed to investigate the association between DII scores and colorectal adenoma (CRA), a pre-cancerous condition.DesignResponses to baseline dietary questionnaires were used calculate DII scores. In a cross-sectional study design, the association between DII scores and CRA prevalence was determined in men and women separately using logistic regression models.SettingTen cancer screening centres across the USA.SubjectsParticipants were those included in the screening arm of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.ResultsAmong the 44 278 individuals included in these analyses, men with diets in the most inflammatory quartile of DII scores had higher odds of all types of CRA (advanced, non-advanced and multiple (>1)) compared with those with diets in the least inflammatory quartile of DII scores. In fully adjusted models, compared with those with DII scores in quartile 1 (least inflammatory), males with DII scores in quartile 3 (adjusted odds ratio (aOR)=1·28; 95 % CI 1·12, 1·47) and quartile 4 (aOR=1·41; 95 % CI 1·23, 1·62) were more likely to have prevalent distal CRA. Higher DII scores, representing a more inflammatory diet, also were weakly associated with a higher prevalence of CRA in women.ConclusionsImplementing an anti-inflammatory diet may be an effective means of primary prevention of CRA, especially in men.


RSBO ◽  
2016 ◽  
Vol 12 (1) ◽  
pp. 41 ◽  
Author(s):  
Elisabete Rabaldo Bottan ◽  
Iara Fiorentin Comunello ◽  
Constanza Marín ◽  
Eduardo Mazzetti Subtil

Introduction and Objective: To evaluate the level of knowledge about oral cancer of students attending public school in one city of Santa Catarina (Brasil). Material and methods: A descriptive cross-sectional study, using primary data collection. Students of last year of elementary school and first year of high school, enrolled in public schools in the city of Itajaí (SC), in 2012, were the target population. The non-probability sample was obtained by convenience. Data were collected through a self-administered questionnaire structured with 13 questions divided into three fields. The level of knowledge was made based on pre-established scores. Results: 1149 instruments were analyzed (80.8% of the target population). The average age of the group was 15.5 years and 54.5% were female. The majority (78%) never had received information about oral cancer. Only 27.9% had cognizance about self-examination of the oral cavity. With regard to knowledge, 87.5% classified as unsatisfactory. For most issues the cognitive field did not identify a significant correlation between knowledge and the variables gender and education. When asked if they would like to participate in educational and preventive activitiesabout oral cancer and other issues related to health, 72.6% expressed interest. Conclusion: The group did not have adequate knowledge on the subject of oral cancer. Facing this reality, and the positive attitude of respondents, the researchers designed and offered an educational program to the research subjects.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Vareda ◽  
T Garcia ◽  
J Rachadell

Abstract Background From disease prevention to health promotion, communication is key for Public Health (PH) practice and, according to the 9th Essential Public Health Operation its goal is to improve populations health literacy and capacity to access, understand and use information. Though social media is frequently presented as a potentially useful tool for PH communication, there is a lack of evidence about its effectiveness and impact on PH outcomes. This study researches Instagram® as a PH tool and aims to know who is using it, what content is shared on the platform and how much engagement there is. Methods This cross-sectional study regards information on 1000 Instagram® posts with the hashtags publichealth, publichealthpromotion, healthpromotion, publichealthmatters and publichealtheducation. Authors categorized post content and creators, and reviewed the number of likes and comments per post to determine engagement. Data analysis was performed on IBM SPSS® Statistics. Results The most common content categories were communicable diseases (n = 383), non-communicable diseases (n = 258) and healthy lifestyles (n = 143). Health professionals post more about communicable diseases (43,6%) and non-professionals about healthy lifestyles (36,1%). Non-professionals (n = 191) post about PH issues almost as much as health professionals (n = 220) and PH associations (n = 201). Most don't reference their sources (n = 821). Posts on communicable diseases have the most likes and comments per post (mean of 172 likes and 3,1 comments). Conclusions Half the Instagram® posts analysed in this study were made by health professionals or organizations. Communicable diseases, non-communicable diseases and healthy lifestyles were the most frequent content categories and had the most engagement. The majority of posts didn't reference their sources. Though Instagram® seems to be a potential PH communication tool, further research is needed to confirm its benefits for PH. Key messages Social media platforms like Instagram® are potentially powerful tools for PH communication. There is a need to understand the efficacy of social media as health promotion tools.


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