A study of water and sanitation access trends in Peru: where do inequities persist?

2014 ◽  
Vol 4 (3) ◽  
pp. 499-508 ◽  
Author(s):  
Betsy Eagin ◽  
Jay P. Graham
Keyword(s):  
Surface Water ◽  
Demographic And Health Surveys ◽  
Significant Progress ◽  
Open Defecation ◽  
Point Change ◽  
Household Level ◽  
Access To Water ◽  
High Risk Populations ◽  
Using Data ◽  
Made In

Peru has made significant progress in increasing access to water supply and sanitation (WS&S). It is unclear, however, if improvements have been equitable and whether certain sub-populations are making equivalent progress. This study explored trends in access to WS&S throughout Peru using data from Demographic and Health Surveys. The study focused on the worst forms of household-level WS&S access, including use of untreated surface water and the practice of open defecation (OD). The prevalence of access and the average annual percentage point change in access were analyzed by quintiles of wealth, urban and rural residence, political regions of Peru, and language for the years 2000, 2004, and 2008. The findings indicate that significant progress in access to WS&S has been made in Peru, but that several sub-populations remain underserved. Regions experiencing high levels of OD made dramatic improvements between 2000 and 2008. The poorest urban populations showed an increasing prevalence of OD, and in some cases surpassed poor, rural populations. The use of untreated surface water was reduced between 2000 and 2008, and remained below 5% for the country. An increased focus on targeting high risk populations to improve equity in access is recommended.

Equity in access to water supply and sanitation in Ethiopia: an analysis of EDHS data (2000–2011)

2016 ◽  
Vol 6 (2) ◽  
pp. 320-330 ◽  
Author(s):  
Selamawit Seyoum ◽  
Jay P. Graham
Keyword(s):  
Surface Water ◽  
Water Supply ◽  
Primary Source ◽  
Open Defecation ◽  
Water Supplies ◽  
Urban Rural ◽  
Improved Sanitation ◽  
Access To Water ◽  
Equity In Access ◽  
Water Supply And Sanitation

Significant efforts to improve water supply and sanitation (WS&S) in Ethiopia have been made over the past decade, yet it is unclear how progress has affected different segments of the population. This study used data from Ethiopia's Demographic and Health Survey (2000, 2005, and 2011) to assess trends in: 1) access to improved water supplies; 2) use of improved sanitation; 3) use of untreated surface water as a primary source for drinking water; 4) open defecation; and 5) water transport times greater than 30 minutes. Trends were assessed by urban/rural residence, administrative region and education. The study found increases in access to improved water supplies and reductions in open defecation; however, no progress was observed in the use of improved sanitation. Rural households that reported drinking untreated surface water went from nearly one-third in 2000 to one-fifth in 2011. No improvements were found regarding the reported time spent collecting water. Inequities in WS&S remained high across the country, highlighting the need to focus on these differences and target resources towards sub-populations that lack this fundamental necessity.

Prevalence and Predictors of Surveillance Cameras in Law Enforcement

2016 ◽  
Vol 28 (1) ◽  
pp. 41-60
Author(s):  
Amie M. Schuck
Keyword(s):  
Law Enforcement ◽  
Adoption Process ◽  
Significant Progress ◽  
Law Enforcement Agencies ◽  
The Public ◽  
Surveillance Cameras ◽  
Research Findings ◽  
Using Data ◽  
The Relationship ◽  
Made In

Using data from more than 2,500 law enforcement agencies, the goal of this study was to identify predictors of advanced surveillance technologies. The findings suggest that the adoption of modern surveillance cameras is neither uniform nor comprehensive and that the adoption process is ongoing with agency officials implementing and discontinuing technologies over time. Most important, stakeholders both inside and outside the organization have the greatest influence on the adoption process, and cameras in vehicles and mobile devices are most prevalent in improvised communities. As cameras become smaller and less expensive, they have the potential to democratize surveillance and equalize the relationship between the police and the public during encounters. However, the democratization effect will only occur if implementation is widespread and all segments of the community have an equal voice in the process. The research findings suggest that significant progress still needs to be made in these areas.

Toward quantitative defect analysis using HREM

1994 ◽  
Vol 52 ◽  
pp. 714-715
Author(s):  
David J. Smith
Keyword(s):  
Electron Microscope ◽  
Unit Cell ◽  
Defect Analysis ◽  
Significant Progress ◽  
Detailed Characterization ◽  
Small Unit ◽  
Resolution Electron ◽  
High Resolution Electron Microscope ◽  
Large Unit Cell ◽  
Made In

The electron microscope has evolved to the level where it is now straightforward to record highresolution images from thin samples (t∼10 to 20nm) that are directly interpretable in terms of atomic arrangements. Whilst recorded images necessarily represent two-dimensional projections of the structure, many defects such as dislocations and interfaces may be linear or planar in nature and thus might be expected to be amenable to detailed characterization. In this review, we briefly consider the recent significant progress that has been made in quantitative defect analysis using the high-resolution electron microscope and then discuss some drawbacks to the technique as well as potential scope for further improvements. Surveys of defect modelling for some small-unit-cell materials and interfaces have recently been published, and reference should be made to other papers in this symposium for further examples.The technique of structure imaging originated in the early '70s with observations of large-unit-cell block oxides.

Biomarkers for Early Detection of Colitis-associated Colorectal Cancer - Current Concepts, Future Trends

2020 ◽  
Vol 22 (1) ◽  
pp. 137-145
Author(s):  
Tomasz Mackiewicz ◽  
Aleksander Sowa ◽  
Jakub Fichna
Keyword(s):  
Colorectal Cancer ◽  
Early Detection ◽  
Cancer Development ◽  
Sporadic Colorectal Cancer ◽  
Future Trends ◽  
Significant Progress ◽  
Current Standard ◽  
Risk Of Cancer ◽  
Histological Testing ◽  
Made In

: Colitis-associated colorectal cancer (CAC) remains a critical complication of ulcerative colitis (UC) with mortality of approximately 15%, which makes early CAC diagnosis crucial. The current standard of surveillance, with repetitive colonoscopies and histological testing of biopsied mucosa samples is burdensome and expensive, and therefore less invasive methods and reliable biomarkers are needed. Significant progress has been made thanks to continuous extensive research in this field, however no clinically relevant biomarker has been established so far. This review of the current literature presents the genetic and molecular differences between CAC and sporadic colorectal cancer and covers progress made in the early detection of CAC carcinogenesis. It focuses on biomarkers under development, which can be easily tested in samples of body fluids or breath and, once made clinically available, will help to differentiate between progressors (UC patients who will develop dysplasia) from non-progressors and enable early intervention to decrease the risk of cancer development.

scholarly journals H3ABioNet genomic medicine and microbiome data portals hackathon proceedings

Database ◽  
2021 ◽  
Vol 2021 ◽  
Author(s):  
Faisal M Fadlelmola ◽  
Kais Ghedira ◽  
Yosr Hamdi ◽  
Mariem Hanachi ◽  
Fouzia Radouani ◽  
...  
Keyword(s):  
Ethnic Groups ◽  
Genomic Medicine ◽  
Lessons Learned ◽  
Team Work ◽  
Significant Progress ◽  
Team Members ◽  
Pan African ◽  
Scientific Expertise ◽  
Microbiome Data ◽  
Made In

Abstract African genomic medicine and microbiome datasets are usually not well characterized in terms of their origin, making it difficult to find and extract data for specific African ethnic groups or even countries. The Pan-African H3Africa Bioinformatics Network (H3ABioNet) recognized the need for developing data portals for African genomic medicine and African microbiomes to address this and ran a hackathon to initiate their development. The two portals were designed and significant progress was made in their development during the hackathon. All the participants worked in a very synergistic and collaborative atmosphere in order to achieve the hackathon's goals. The participants were divided into content and technical teams and worked over a period of 6 days. In response to one of the survey questions of what the participants liked the most during the hackathon, 55% of the hackathon participants highlighted the familial and friendly atmosphere, the team work and the diversity of team members and their expertise. This paper describes the preparations for the portals hackathon and the interaction between the participants and reflects upon the lessons learned about its impact on successfully developing the two data portals as well as building scientific expertise of younger African researchers. Database URL: The code for developing the two portals was made publicly available in GitHub repositories: [https://github.com/codemeleon/Database; https://github.com/codemeleon/AfricanMicrobiomePortal].

scholarly journals Rational design of photocatalysts for ammonia production from water and nitrogen gas

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Seokwoo Choe ◽  
Sung Min Kim ◽  
Yeji Lee ◽  
Jin Seok ◽  
Jiyong Jung ◽  
...  
Keyword(s):  
Energy Source ◽  
Rational Design ◽  
Future Research ◽  
Ammonia Production ◽  
Significant Progress ◽  
Nitrogen Gas ◽  
Research Directions ◽  
Effective Strategies ◽  
Future Research Directions ◽  
Made In

AbstractPhotocatalytic N2 reduction has emerged as one of the most attractive routes to produce NH3 as a useful commodity for chemicals used in industries and as a carbon-free energy source. Recently, significant progress has been made in understanding, exploring, and designing efficient photocatalyst. In this review, we outline the important mechanistic and experimental procedures for photocatalytic NH3 production. In addition, we review effective strategies on development of photocatalysts. Finally, our analyses on the characteristics and modifications of photocatalysts have been summarized, based on which we discuss the possible future research directions, particularly on preparing more efficient catalysts. Overall, this review provides insights on improving photocatalytic NH3 production and designing solar-driven chemical conversions.

scholarly journals Identification and Validation of New Cancer Stem Cell-Related Genes and Their Regulatory microRNAs in Colorectal Cancerogenesis

Biomedicines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 179
Author(s):  
Kristian Urh ◽  
Margareta Žlajpah ◽  
Nina Zidar ◽  
Emanuela Boštjančič
Keyword(s):  
Experimental Validation ◽  
Target Gene ◽  
Bioinformatics Analysis ◽  
Early Carcinoma ◽  
Significant Progress ◽  
Formalin Fixed Paraffin ◽  
Formalin Fixed Paraffin Embedded ◽  
Node Metastases ◽  
Formalin Fixed ◽  
Made In

Significant progress has been made in the last decade in our understanding of the pathogenetic mechanisms of colorectal cancer (CRC). Cancer stem cells (CSC) have gained much attention and are now believed to play a crucial role in the pathogenesis of various cancers, including CRC. In the current study, we validated gene expression of four genes related to CSC, L1TD1, SLITRK6, ST6GALNAC1 and TCEA3, identified in a previous bioinformatics analysis. Using bioinformatics, potential miRNA-target gene correlations were prioritized. In total, 70 formalin-fixed paraffin-embedded biopsy samples from 47 patients with adenoma, adenoma with early carcinoma and CRC without and with lymph node metastases were included. The expression of selected genes and microRNAs (miRNAs) was evaluated using quantitative PCR. Differential expression of all investigated genes and four of six prioritized miRNAs (hsa-miR-199a-3p, hsa-miR-335-5p, hsa-miR-425-5p, hsa-miR-1225-3p, hsa-miR-1233-3p and hsa-miR-1303) was found in at least one group of CRC cancerogenesis. L1TD1, SLITRK6, miR-1233-3p and miR-1225-3p were correlated to the level of malignancy. A negative correlation between miR-199a-3p and its predicted target SLITRK6 was observed, showing potential for further experimental validation in CRC. Our results provide further evidence that CSC-related genes and their regulatory miRNAs are involved in CRC development and progression and suggest that some them, particularly miR-199a-3p and its SLITRK6 target gene, are promising for further validation in CRC.

Surface water quality classification using data mining approaches: Irrigation along the Aladag River*

2021 ◽  
Author(s):  
Mohammad Taghi Sattari ◽  
Hajar Feizi ◽  
Muslume Sevba Colak ◽  
Ahmet Ozturk ◽  
Fazli Ozturk ◽  
...  
Keyword(s):  
Data Mining ◽  
Water Quality ◽  
Surface Water ◽  
Surface Water Quality ◽  
Quality Classification ◽  
Water Quality Classification ◽  
Using Data

scholarly journals Health and Housing Energy Expenditures: A Two-Part Model Approach

Processes ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 943
Author(s):  
Fátima Lima ◽  
Paula Ferreira ◽  
Vítor Leal
Keyword(s):  
Low Income ◽  
Health Expenditures ◽  
Household Level ◽  
Energy Expenditures ◽  
Health And Wellbeing ◽  
Health Gains ◽  
Key Factor ◽  
Using Data ◽  
Part Model ◽  
Model Approach

Interest in the interaction between energy and health within the built environment has been increasing in recent years, in the context of sustainable development. However, in order to promote health and wellbeing across all ages it is necessary to have a better understanding of the association between health and energy at household level. This study contributes to this debate by addressing the case of Portugal using data from the Household Budget Survey (HBS) microdata database. A two-part model is applied to estimate health expenditures based on energy-related expenditures, as well as socioeconomic variables. Additional statistical methods are used to enhance the perception of relevant predictors for health expenditures. Our findings suggest that given the high significance and coefficient value, energy expenditure is a relevant explanatory variable for health expenditures. This result is further validated by a dominance analysis ranking. Moreover, the results show that health gains and medical cost reductions can be a key factor to consider on the assessment of the economic viability of energy efficiency projects in buildings. This is particularly relevant for the older and low-income segments of the population.

scholarly journals The Pivotal Player: Components of NF-κB Pathway as Promising Biomarkers in Colorectal Cancer

2021 ◽  
Vol 22 (14) ◽  
pp. 7429
Author(s):  
Matthew Martin ◽  
Mengyao Sun ◽  
Aishat Motolani ◽  
Tao Lu
Keyword(s):  
Colorectal Cancer ◽  
Biological Response ◽  
Significant Progress ◽  
Therapeutic Approaches ◽  
Successful Development ◽  
Diagnostic Screening ◽  
Proteomic Data ◽  
Large Groups ◽  
Made In

Over the last several decades, colorectal cancer (CRC) has been one of the most prevalent cancers. While significant progress has been made in both diagnostic screening and therapeutic approaches, a large knowledge gap still remains regarding the early identification and treatment of CRC. Specifically, identification of CRC biomarkers that can help with the creation of targeted therapies as well as increasing the ability for clinicians to predict the biological response of a patient to therapeutics, is of particular importance. This review provides an overview of CRC and its progression stages, as well as the basic types of CRC biomarkers. We then lay out the synopsis of signaling pathways related to CRC, and further highlight the pivotal and multifaceted role of nuclear factor (NF) κB signaling in CRC. Particularly, we bring forth knowledge regarding the tumor microenvironment (TME) in CRC, and its complex interaction with cancer cells. We also provide examples of NF-κB signaling-related CRC biomarkers, and ongoing efforts made at targeting NF-κB signaling in CRC treatment. We conclude and anticipate that with more emerging novel regulators of the NF-κB pathway being discovered, together with their in-depth characterization and the integration of large groups of genomic, transcriptomic and proteomic data, the day of successful development of more ideal NF-κB inhibitors is fast approaching.

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