Tinospora cordifolia (Giloy): Phytochemistry, Ethnopharmacology, Clinical Application and Conservation Strategies

2020 ◽  
Vol 21 (12) ◽  
pp. 1165-1175
Author(s):  
Pradeep Kumar ◽  
Madhu Kamle ◽  
Dipendra K. Mahato ◽  
Himashree Bora ◽  
Bharti Sharma ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Alternative Medicine ◽  
Clinical Application ◽  
Future Generations ◽  
Tinospora Cordifolia ◽  
Conservation Strategies ◽  
Pharmacological Properties ◽  
Anti Oxidant ◽  
Ancient Times ◽  
Anti Inflammatory

Tinospora cordifolia (Giloy) is a medicinal plant used in folk and Ayurvedic medicines throughout India since ancient times. All the parts of the plant are immensely useful due to the presence of different compounds of pharmaceutical importance belonging to various groups as alkaloids, diterpenoid lactones, glycosides, steroids, sesquiterpenoid, and phenolics. These compounds possess pharmacological properties, which make it anti-diabetic, antipyretic, anti-inflammatory, anti-oxidant, hepato-protective, and immuno-modulatory. However, due to the increasing population, there is an inadequate supply of drugs. Therefore, this review focuses on phytochemistry, ethnopharmacology, clinical application and its conservation strategies so that the plant can be conserved for future generations and utilized as alternative medicine as well as to design various pharmacologically important drugs.

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

scholarly journals Medicinal properties of Abutilon indicum

2018 ◽  
Vol 1 (1) ◽  
pp. 1-4
Author(s):  
S Rajeshwari ◽  
SP Sevarkodiyone
Keyword(s):  
Medicinal Plant ◽  
Traditional Medicine ◽  
Phytochemical Analysis ◽  
Vaginal Infections ◽  
Anti Cancer ◽  
Anti Oxidant ◽  
Medicinal Properties ◽  
Anti Inflammatory ◽  
Larvicidal Activities ◽  
Abutilon Indicum

Abutilon indicum is a common Indian shrub, belonging to the family Malvaceae; Also known as Mallow in english, Abutilon indicum is used as a medicinal plant. It has been extensively used as a traditional medicine as a laxative, emollient, analgesic, anti-diabetic, anti-inflammatory and blood tonic agent and also in the treatment of leprosy, urinary disease, jaundice, piles, relieving thirst, cleaning wounds and ulcers, vaginal infections, diarrhea, rheumatism, mumps, pulmonary tuberculosis, bronchitis, allergy, blood dysentery, some nervous and some ear problems. Various studies on the plant extract have been performed to confirm the anti-oxidant, anti-bacterial, analgesic, anti-inflammatory, anti-cancer, hepato-protective, immuno-modulatory and larvicidal activities of the plant. This plant is often used as a medicinal plant and is considered invasive on certain tropical islands. In traditional medicine, A. indicum is used as a aphrodisiac, demulcent, diuretic, laxative, pulmonary and sedative (leaves). The bark is astringent and diuretic; laxative, expectorant and demulcent (seeds); laxative and tonic, anti-inflammatory and anthelmintic (plant); analgesic (fixed oil); diuretic and for leprosy (roots). The plant is very much used in Siddha medicines. In fact, the bark, root, leaves, flowers and seeds are all used for medicinal purposes by Tamils. The leaves are also used to treat for pile complaints. The flowers are traditionally used to increase semen in men. The phytochemical analysis showed the Presence of Alkaloid, Saponins, Amino acid, Flavonoids, Glycosides and steroids. This plant exhibits several potential pharmacological activities. A review on the various studies on the plant has been provided for the purpose of understanding its medicinal properties.

scholarly journals Pharmacological effects of Sapindus mukorossi

2012 ◽  
Vol 54 (5) ◽  
pp. 273-280 ◽  
Author(s):  
Aparna Upadhyay ◽  
D.K. Singh
Keyword(s):  
Medicinal Plant ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Effects ◽  
Tropical Regions ◽  
Multipurpose Tree ◽  
Phytochemical Composition ◽  
Anti Inflammatory ◽  
Different Parts ◽  
Research Studies

Sapindus mukorossi is an extremely valuable medicinal plant, distributed in tropical and sub-tropical regions of Asia. The aim of present review is to form a short compilation of the phytochemical composition and pharmacological properties of this multipurpose tree. The main phytoconstituents isolated and identified from different parts of this plant are triterpenoidal saponins of oleanane, dammarane and tirucullane type. The structure and chemical names of all the types of triterpenoidal saponins reported in Sapindus mukorossi are included in this review. Many research studies have been conducted to prove the plant's potential as being spermicidal, contraceptive, hepatoprotective, emetic, anti-inflammatory and anti-protozoal. The present review highlights some of the salient pharmacological uses of Sapindus mukorossi.

scholarly journals The Multifaced Actions of Curcumin in Pregnancy Outcome

Antioxidants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 126
Author(s):  
Giovanni Tossetta ◽  
Sonia Fantone ◽  
Stefano Raffaele Giannubilo ◽  
Daniela Marzioni
Keyword(s):  
Natural Compound ◽  
Curcuma Longa ◽  
Human Diet ◽  
Beneficial Effects ◽  
Toxic Agents ◽  
Anti Oxidant ◽  
Ancient Times ◽  
Anti Inflammatory ◽  
Pleiotropic Functions

Curcumin, also known as diferuloylmethane, is the main polyphenolic substance present in the rhizomes of Curcuma longa L. This plant showed many beneficial effects and has been used since ancient times for both food and pharmaceutical purposes. Due to its pleiotropic functions, curcumin consumption in the human diet has become very common thanks also to the fact that this natural compound is considered quite safe as it does not have serious side effects. Its functions as an anti-inflammatory, anti-oxidant, neuroprotective, immunomodulatory, anti-toxicant, anti-apoptotic, and anti-diabetic compound are already known and widely demonstrated. There are numerous studies concerning its effects on various human pathologies including cancer, diabetes and arthritis while the studies on curcumin during pregnancy have been performed only in animal models. Data concerning the role of curcumin as anti-inflammatory compound suggest a possible use of curcumin in managing pregnancy complications such as Preeclampsia (PE), Gestational Diabetes Mellitus (GDM), Fetal Growth Restriction (FGR), PreTerm Birth (PTB), and exposure to toxic agents and pathogens. The aim of this review is to present data to support the possible use of curcumin in clinical trials on human gestation complications.

scholarly journals Assessment of Chemical Properties of Tinospora Cordifolia

2020 ◽  
Vol 6 (12) ◽  
pp. 45-49
Author(s):  
Nafeesa Begum and Ranjith Y
Keyword(s):  
Urinary Tract ◽  
Chemical Analysis ◽  
Medicinal Plant ◽  
Urinary Tract Infections ◽  
Skin Diseases ◽  
Chemical Properties ◽  
Tinospora Cordifolia ◽  
Anti Inflammatory ◽  
Tract Infections ◽  
Important Medicinal Plant

The plant produces have phyto medicine this can be derived from bark, leaf, flower, fruit and seeds (Raghunathan and Rama Mitra, 1982). In the present study the phyto chemical analysis were carried out in leaf and bark of Tinosporacordifolia. Tinosporacordifolia is an important medicinal plant used in ayurvedic system of medicine. The stem of the plant is grayish brown in colour and bitter in taste. The stem is soft wooded, dry. The plant has been used as an anti spasmodic, anti inflammatory, Jaundice, Diabetes, seminal weakness, urinary tract infections, fever, skin diseases and expectorant, carminative, digestive, anti stress and aphrodisiac.

scholarly journals Phytomedicine - A Holistic Approach in Dentistry

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Rita Zarina ◽  
Jaini. J. L ◽  
Ektah Khosla
Keyword(s):  
Medicinal Plant ◽  
Folk Medicine ◽  
Holistic Approach ◽  
Herbal Products ◽  
Antibiotic Overuse ◽  
Ancient Times ◽  
Anti Inflammatory ◽  
Sedative Agents ◽  
Microbiological Properties

<div><p><em>Herbal products have been used since ancient times in folk medicine, involving both eastern and western medicinal traditions. Many plants with biological and anti-microbiological properties have been studied since there has been a relevant increase in the incidence of antibiotic overuse and misuse. In dentistry Phytomedicines has been used as anti-inflammatory, antibiotic, analgesic and sedative agents. This paper highlights certain medicinal plant which is used in dentistry as alternative and in holistic way.</em></p></div>

Analgesic activity and anti-inflammatory activity of methanolic extract of plant Sida cordata in carrageenan-induced paw edema in rats

2021 ◽  
pp. 143-146
Author(s):  
Prajakta P Shinde ◽  
Shahu D Khule ◽  
Sneha Sonawane ◽  
Suvarna Shelke
Keyword(s):  
Methanol Extract ◽  
Methanolic Extract ◽  
Diabetic Control ◽  
Diabetic Rats ◽  
Clinical Practices ◽  
Increased Risk ◽  
Anti Oxidant ◽  
Ancient Times ◽  
Anti Inflammatory ◽  
Altered Lipid

India has rich heritage of use of medicinal plants in clinical practices since ancient times. Diabetes mellitus is a group of syndromes characterized by hyperglycemia, altered lipid, carbohydrate and protein metabolism, and an increased risk of vascular disease complications. More than 400 plant species have been recorded to display hypoglycemic effects, but only a few of them have been investigated. Although many drugs are available to control the diabetes but has several adverse effects. The plant Sida cordata activities have been reported such as Antibacterial, Antitumor, Antifungal, Antiulcer, Antitussive, Anti-inflammatory, Anti-malarial, Anti-oxidant, Analgesic, Antidepressant, Antihyperglycemic, Hepatoprotective in ayurvedic system of medicine. This research was conducted undertaken In order to investigate the anti-diabetic activity of methnolic extract of Sida cordata. The two dose (100 and 200 mg/kg) methnolic extract of Sida cordata used for treatment of Alloxan induced diabetic rats. The glucose level was significantly (p<0.01) high in Alloxan control rats when opposed to normal control. But the level of glucose was significantly (p<0.01) decreased after 7th day in diabetic rats treated with methanol extract (200 mg/kg) as compared with diabetic control rats.

Therapeutic and nutritional values of Kumari (Aloe Vera)-a review

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
Renu P. Raokhande
Keyword(s):  
Medicinal Plant ◽  
Aloe Vera ◽  
Ayurvedic Medicine ◽  
Nutritional Values ◽  
Health Related ◽  
Ancient Times ◽  
Anti Inflammatory

Kumari (Aloe Vera) is well known and used worldwide as a medicinal plant. Since ancient times, aloe Vera has provided human-mankind with numerous valuable benefits. Aloe Vera is the most impressive and solution based medicinal based herb invented by nature. Various scientific researches has also shown its beneficiary values and various anti-tumor and anti-inflammatory properties. In Indian Ayurvedic medicine, Aloe Vera is applied for various health related aids. It is also regarded as the plant of balance between vatta, pitta, kapha-it is one of the very few plants that hold these qualities. The aim to present a study on Kumari (aloe Vera) is to get back to the ancient roots of Ayurvedic medicines and reap in all the benefits of these.

scholarly journals GILO (TINOSPORA CORDIFOLIA (WILLD.) MIERS: A WONDER DRUG OF UNANI SYSTEM OF MEDICINE

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Mohd Afsahul Kalam ◽  
Arshia Noor ◽  
Ifra Qayoom ◽  
Riehana Gani ◽  
Humma Humma
Keyword(s):  
Medicinal Plant ◽  
Broad Spectrum ◽  
Critical Review ◽  
Tinospora Cordifolia ◽  
Pharmacological Properties ◽  
Classical Literature ◽  
Therapeutic Uses ◽  
Therapeutic Properties ◽  
Wonder Drug

Gilo or Tinospora cordifolia is considered as a wonder drug of Unani System of Medicine because of its broad-spectrum therapeutic properties. It is an herbaceous vine, commonly grown in tropical India, and is being widely used in AYUSH system and unorganized systems (folk, tribal, native) of medicine. It is a storehouse of various phyto constituents like alkaloids, terpenoids, glycosides, hormones, polysaccharides, steroids, minerals etc. Its main pharmacological properties are antipyretic, anti-diabetic, antioxidant, hepato protective etc. Now a days, Gilo is being extensively assessed for its immunomodulator activity and it is proving to be a promising herb in this respect. The current study presents a critical review on the morphology, habitat, phytochemistry, pharmacological actions and therapeutic uses of this medicinal plant as mentioned in the classical literature of Unani System of Medicine as well as to cover its recent researches.

scholarly journals Phytochemical and Therapeutic Potential of Alstonia scholaris R. Br.- A Magical Traditional Plant

2021 ◽  
pp. 41-51
Author(s):  
Neeraj Bainsal ◽  
Pratibha Aggarwal ◽  
Kundan Singh Bora
Keyword(s):  
Medicinal Plant ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Health Condition ◽  
Pharmacological Properties ◽  
Alstonia Scholaris ◽  
The Family ◽  
Ancient Times ◽  
Phytochemical Constituents ◽  
Important Medicinal Plant

Alstonia scholaris R.Br. commonly known as devil tree is a potential medicinal plant belongs to the family Apocynaceae. Endemic to the geographical areas like India, China and Bangladesh. From the ancient times it is an important medicinal plant containing medicinal potential viabilities to treat number of health condition such as stomach ache, diarrhea, abdominal disorders etc. using various preparations like decoctions, powders etc. Its parts can be administered for the treatment of various diseases. The morphological, organoleptic and microscopic characteristics are also established. It is reported to be rich source of alkaloids. Also, it contains chemical constituents like irioids, coumarins, sugars, oils, phenolics etc. The phytochemical constituents contained in each part are described in the present review. The plant was investigated by the scientists, researchers while performing the experiments on animals they concluded that the plant have pharmacological properties such as antimicrobial, antidiarreal, antitussive, antiasthmatic, immunostimulatory, antidiabetic etc. which are discussed in the article.

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