scholarly journals COVID-19 IN CHILDREN: A NARRATIVE REVIEW

2021 ◽  
Vol 17 ◽  
Author(s):  
Jennifer F Ha
Keyword(s):  
Vulnerable Populations ◽  
Scientific Community ◽  
Literature Search ◽  
Narrative Review ◽  
Age Group ◽  
Disease Course ◽  
The Third ◽  
Bibliographic Search ◽  
Timely Fashion ◽  
Pertinent Information

Introduction: The coronavirus disease 2019 (COVID-19) pandemic is caused by the third known zoonotic coronavirus. It is a disease that does not spare any age group. The scientific community has been inundated with information since January 2020. This review aims to summarise pertinent information relating to COVID-19 in children. Method: Literature search was conducted in 2020 on the PubMed, MEDLINE, and Embase databases, with the keywords “COVID 19” and “children”. A bibliographic search of articles included was also undertaken. The abstracts were scanned to assess their appropriateness to be included in this narrative review. The data was updated on 11th April 2020. Result: The aetiology, transmission, incubation, pathophysiology, clinical features and complications, and management are discussed in this study. Conclusion: Our understanding of COVID-19 is evolving as more reports are being published. The growth of SARS-CoV2 is limited in children and they are often asymptomatic. The disease course is also milder. Continued research to understand its effect in children is important to help us manage the disease in these vulnerable populations in a timely fashion.

scholarly journals The Potential Preventive Effect of Pregnancy and Breastfeeding on Multiple Sclerosis

2021 ◽  
Vol 84 (2) ◽  
pp. 71-84
Author(s):  
Mohsen Ali Alhomoud ◽  
Abdul Sattar Khan ◽  
Iftetah Alhomoud
Keyword(s):  
Multiple Sclerosis ◽  
Neurological Disease ◽  
Literature Search ◽  
Current Evidence ◽  
Obstetric Outcomes ◽  
Preventive Effect ◽  
Third Trimester ◽  
The Third ◽  
The Central Nervous System

<b><i>Background:</i></b> Multiple sclerosis (MS) is an inflammatory demyelinating chronic neurological disease that affects the central nervous system of young adults and their quality of life. Several studies have investigated the effects of pregnancy and breastfeeding on MS. However, the evidence regarding the influence of pregnancy and breastfeeding on MS is still accumulating. This review aimed to summarize the current evidence regarding the effects of pregnancy and breastfeeding on MS. <b><i>Summary:</i></b> A systematic electronic literature search of the PubMed and Embase databases was conducted to determine relevant published articles. The eligible studies were summarized and evaluated in tables. <b><i>Key Messages:</i></b> The majority of the studies indicated that pregnancy appears to lower the rate of MS relapses, particularly in the third trimester. The evidence regarding the effect of breastfeeding on MS remains inconsistent. Despite reports of negative obstetric outcomes in some pregnant women with MS, pregnancies in women with MS should not be categorized as high-risk pregnancies.

scholarly journals A clinical staging proposal of the disease course over time in non-severe patients with coronavirus disease 2019

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yiting Lin ◽  
Yiqun Wu ◽  
Ping Zhong ◽  
Bingbo Hou ◽  
Jielan Liu ◽  
...  
Keyword(s):  
Inflammatory Markers ◽  
Clinical Signs ◽  
Clinical Staging ◽  
Disease Course ◽  
Prodromal Phase ◽  
The Third ◽  
Convalescent Phase ◽  
Secondary Damage ◽  
Remission Phase ◽  
Over Time

AbstractInformation on the clinical staging of coronavirus disease 2019 (COVID-19) is still limited. This study aimed to propose a clinical staging proposal of the disease course in non-severe patients with COVID-19. In this retrospective study, 108 non-severe patients with COVID-19 were grouped according to the duration from symptoms onset to hospital admission: ≤ 1 week, > 1 to 2 weeks, > 2 to 3 weeks, > 3 to 5 weeks, respectively. The dynamic changes of clinical signs were profiled across the four groups. A clinical staging proposal of the disease course over time was proposed from the perspective of the interaction between the virus and host. The prodromal phase, characterized by pneumonia, significant lymphopenia, and slightly elevated inflammatory markers, occurred in the first week after symptoms onset. In the second week, all the hematological and inflammatory markers were at the peak or bottom. Meanwhile, progressive pneumonia as well as the secondary damage of other organs (e.g. cardiac damage, coagulopathy, etc.) was significant during this period, making the disease progress into the apparent manifestation phase. In the third week, the improvement of the majority of clinical signs accompanied by a relatively high degree of inflammatory response defined the remission phase. After 3 weeks, patients were in the convalescent phase, in which all the indicators were maintained at a relatively normal level. We concluded that the disease course over time in non-severe patients with COVID-19 could be divided into four phases: the prodromal phase (in the first week), the apparent manifestation phase (in the second week), the remission phase (in the third week), and the convalescent phase (after 3 weeks), respectively. In clinical practice, tailored therapies should be considered seriously in different stages of the disease course.

Recurrent Adolescent Suicidal Behavior

PEDIATRICS ◽  
1977 ◽  
Vol 60 (4) ◽  
pp. 605-608
Author(s):  
Matilda S. McIntire ◽  
Carol R. Angle ◽  
Richard L. Wikoff ◽  
Marilyn L. Schlicht
Keyword(s):  
Adolescent Suicide ◽  
Suicide Attempts ◽  
Public Health Problem ◽  
Poison Control ◽  
Age Group ◽  
Emergency Room Visits ◽  
Suicidal Risk ◽  
Destructive Behavior ◽  
The Third ◽  
Completed Suicide

Suicide is the third leading cause of death among people in the age group 15 to 25 years.1 Self-destructive behavior in children and adolescents is a continuum that ranges from drug intoxications to gestures of low lethality to suicide attempts with high lethality of intent. In our survey of 1,100 self-poisonings in people aged 6 to 18 who were seen at poison control centers we found an incidence of 220 self-poisonings for every fatality.2 This is higher but comparable to other estimates of 50 to 150 suicide gestures for every reported death from suicide in the adolescent.3-6 Suicide attempts may account for 12% of all emergency room visits.7 This represents a public health problem of the first magnitude. It is ironically tragic that many of the adolescent suicide deaths are unintentioned-the victim did not really intend to die. In our collaborative poison study, for example, none of the six deaths could be called intended. The adolescents were not victims of suicide but of pharmacologic roulette. The single best correlate of suicidal risk appears to be lethality of intent. A diagnosis of suicide attempt, as contrasted to a gesture, implies both a lethality of intent coupled with a mature concept of death as an irreversible state. Lethality is defined by Shneidman8 as the probability of an individual's killing himself in the immediate future. In classifying all deaths as intentioned, subintentioned, and unintentioned as contrasted to the traditional classifications of natural, accidental, suicidal, and homicidal he has used the dimension of lethality to cut across the terms attempted, threatened, and completed suicide.

Tingkat Kecemasan Ibu Hamil Trimester III dalam Menghadapi Persalinan

2021 ◽  
Vol 3 (1) ◽  
pp. 18-24
Author(s):  
Nilda Yulita Siregar ◽  
Cici Fitrayanti Kias ◽  
Nurfatimah Nurfatimah ◽  
Fransisca Noya ◽  
Lisda Widianti Longgupa ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Preterm Labor ◽  
Community Health Center ◽  
Sampling Technique ◽  
Descriptive Study ◽  
Age Group ◽  
Third Trimester ◽  
Pregnancy And Childbirth ◽  
The Third ◽  
Fear And Anxiety

Introduction: Fear and anxiety during pregnancy and childbirth can cause problems such as preterm labor and low birth weight. Purpose: The purpose of this study was to determine the level of anxiety of third-trimester pregnant women in dealing with labor. Methods: This type of research is a descriptive study and analyzed with frequency distribution. The population was all pregnant women in the third trimester who were in the working area of ​​the Mapane Community Health Center with a total of 37 people. The sampling technique used total sampling. The results showed that only 8.1% of pregnant women experienced mild anxiety, while 91.9% did not experience anxiety. pregnant women who experience mild anxiety are 20% in the risk age group, 20% with diploma education, 11.5% in mothers who do not work, 60% in primigravidas, and 15.8% in mothers who do not get support from their husbands. Anxiety occurs mostly in primigravida because it is the first experience of pregnancy. It suggested for village midwives providing information about pregnancy and childbirth, especially for primigravida mothers, and involving their husbands in posyandu activities for pregnant women.

scholarly journals Anaerobic fitness of a Sample of Omani Children: Age group from 9-13 years

2010 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Hisham Ahmed Moheeb ◽  
Mansoor Al-Tauqi ◽  
Khalifa Bin Mubarak Al Jadeedi
Keyword(s):  
Motor Skills ◽  
Age Groups ◽  
Anaerobic Capacity ◽  
Age Group ◽  
Fourth Group ◽  
The Third ◽  
Stages Of Growth ◽  
Steady Rate ◽  
Capacity Level ◽  
Vertical Jumping

This study aimed to identify the anaerobic capacity level of a sample of Omani children. The sample included 197 children between the ages of 9 to 13 years. The Running-based Anaerobic Sprint Test (RAST) was used. The sample was divided into five groups. The first group comprised the nine-year olds (19 children), the second group comprised the ten-year olds (22 children), the third group comprised the eleven-year olds (52 children), the fourth group comprised the 12-year olds (43 children), and the fifth comprised the 13-year olds (61 children). The results showed that the anaerobic capacity level improved during the stages of growth. The level of improvement achieved in 13-year old children was the highest compared to the other age-groups (P S 0.000). This improvement was not at a steady rate. It occurred through booms that coincided with growth which appears in practice through the evolution of not only the level of values on the amount of effort, but also in the level of some related motor skills. It showed a positive correlation between the values of the anaerobic capacity level, the time of running 100 meters and vertical jumping (p S 0.01). Accordingly, this phase can be considered one of those booms. Key words: anaerobic capacity, (Running-based Anaerobic Sprint Test (RAST), Omani children, the 100 meters running, vertical jumping.

scholarly journals The Wingate Anaerobic Test, a Narrative Review of the Protocol Variables That Affect the Results Obtained

2021 ◽  
Vol 11 (16) ◽  
pp. 7417
Author(s):  
Arkaitz Castañeda-Babarro
Keyword(s):  
Literature Search ◽  
Web Of Science ◽  
Cycle Ergometer ◽  
Narrative Review ◽  
Improve Performance ◽  
Wingate Anaerobic Test ◽  
Warm Up ◽  
Cycling Test ◽  
Anaerobic Test

The Wingate Anaerobic Test (WAT) has been widely used since its creation in 1974. The WAT involves performing a 30 s “all-out” cycling test. The test is currently applied with some modifications, partly due to the evolution of the material used to perform it. The purpose of this text is to act as a guide for the correct use and application of the test, as well as to highlight the importance of controlling many of the variables that may influence its results. Methods: A literature search was conducted in PUBMED/MEDLINE and Web of Science with different combinations of keywords all related to the WAT to obtain a search of 113 papers. Results and discussion: It was observed that variables such as the duration of the test or the resistance used in the cycle ergometer must be adjusted according to the objective and the population evaluated, while others such as the warm-up or the supplementation of different substances can improve performance on the WAT. Conclusions: In order to apply the WAT correctly, variables such as duration, resistance used or warm-up time and intensity must be adjusted according to the evaluated subjects and the aim of the study. Other variables such as position on the bike or equipment used should also be controlled if we want to guarantee its replicability.

Efficiency and safety of sclerotherapy for recurrent nodular goiter

2020 ◽  
pp. 39-51
Author(s):  
G. V. Rodoman ◽  
I. R. Sumedi ◽  
N. V. Sviridenko ◽  
T. I. Shalaeva ◽  
M. M. Meloyan
Keyword(s):  
Minimally Invasive ◽  
Severe Pain ◽  
Nodular Goiter ◽  
Treatment Method ◽  
Age Group ◽  
Invasive Treatment ◽  
The Third ◽  
Invasive Method ◽  
Functional Autonomy

At present, patients with recurrent nodular goiter account for a significant portion of patients operated on for nodular goiter. At the same time, the comorbid background characteristic of this age group and the technical difficulties of the intervention on cicatricial tissues of the neck cause a high risk of complications of the operation, 3–7 times higher than with primary thyroid interventions. The aim of the study was to evaluate the effectiveness and safety of treatment of recurrent nodular goiter using an alternative minimally invasive method — sclerotherapy. The study included 30 patients previously operated on for nodular goiter. All had 4 courses of sclerotherapy, each included 5 sessions with a frequency of 1 session per week, followed by a follow-up period of 3 months. Polydocanol was used as a sclerosant. The analysis showed that sclerotherapy for recurrent nodular goiter allows all patients to reduce recurrent nodular formations, and in almost a third of cases, complete reduction of the nodes. On average, the decrease in the volume of thyroid residues was 9.6 ± 1.5 ml, and the size of nodular formations decreased by 17.2 ± 1.3 mm (3.7 times — from 23.6 ± 1.4 mm to 6.4 ± 0.7 mm, P <0.001). Nodes more than 3 cm, initially 19 %, ceased to be detected after the third course of sclerotherapy. In all cases, managed to eliminate hormonal imbalances in patients who initially had functional autonomy, as well as signs of compression of the neck organs. At the same time, sclerotherapy of nodules of the thyroid gland using polydocanol as a sclerosant is a safe minimally invasive treatment method, is not accompanied by severe pain and the risk of hypoparathyroidism and laryngeal paresis.

Mineral chemistry, P-T pseudosection and in-situ U-Th-Pbtotal monazite geochronology of Banded Iron Formation from Bundelkhand craton North-Central India, and its geodynamic significance

2021 ◽  
Author(s):  
Mohd Baqar Raza ◽  
Pritam Nasipuri ◽  
Hifzurrahman
Keyword(s):  
Central India ◽  
Mineral Chemistry ◽  
Iron Formation ◽  
Age Group ◽  
Banded Iron Formation ◽  
Tectonic Zone ◽  
Third Age ◽  
The Third ◽  
Hydrothermal Activities

&lt;p&gt;The Banded Iron Formation (BIF) in Bundelkhand craton (BuC) occurred as supracrustals associated with TTG&amp;#8217;s, amphibolites, calcsilicate rocks, and quartzite within the east-west trending Bundelkhand tectonic zone (BTZ). The BIFs near Mauranipur do not show any prominent iron-rich and silica-rich layer band and are composed of garnet, amphibole, quartz, and magnetite. The volumetrically dominant monoclinic-amphiboles are grunerite in composition. X&lt;sub&gt;Mg&lt;/sub&gt; of grunerite varies between 0.39-0.37. The garnets are Mn-rich, the X&lt;sub&gt;Spss&lt;/sub&gt; of garnet ranges from 0.26-0.20, X&lt;sub&gt;Pyp&lt;/sub&gt; and X&lt;sub&gt;Grs &lt;/sub&gt;vary between 0.10-0.06 and 0.07-0.05, respectively. P-T pseudosection analysis indicates that by destabilizing iron-silicate hydroxide phases through a series of dehydration and decarbonation reactions, amphibole and garnet stabilized in BIF at temperature 400-450&amp;#176;C and pressure 0.1-0.2 GPa.&lt;/p&gt;&lt;p&gt;Massive type BIFs have monazite grains that vary from 10 to 50 &amp;#181;m in size, yield three distinct U-Th-Pb&lt;sub&gt;total&lt;/sub&gt; age clusters. 10-20 &amp;#181;m sized monazite grains yield the oldest age, 3098&amp;#177;95 Ma. 2478&amp;#177;37 Ma average age is obtained from the second group, which is relatively larger and volumetrically predominant. The third age group of Monaiztes gives an age of 2088&amp;#177;110 Ma. ~3100 Ma monazite suggests the older supracrustal rocks of Bundelkhand craton, similar to those obtained from Singhbhum and the Dharwar craton. The 2478&amp;#177;37 Ma age is constrained as the timing of metamorphism and stabilization of BuC. The third age group, 2088&amp;#177;110 Ma probably associated with renewed hydrothermal activities, leading to rifting and emplacement of mafic dykes in BuC.&lt;/p&gt;

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