The Consumption of Folic Acid During Preconception Period and its Related Knowledge among Iranian Women

2020 ◽  
Vol 16 (1) ◽  
pp. 33-38
Author(s):  
Roghieh Bayrami ◽  
Alireza Didarloo ◽  
Afsaneh Asadinejad

Background: The use of folic acid in the preconception stage can prevent neural tube defects if taken at the right time. Objective: The purpose of this study was to investigate the intake of folic acid in the preconception period and its related knowledge among Iranian women. Materials and Methods: In this cross-sectional study, 230 married women who had decided to become pregnant were selected from health centers using the multistage cluster sampling method in Urmia-Iran, in 2018. The data collection tool was a self-structured, valid, reliable questionnaire consisting of the following parts: women’s demographic data, use of folic acid, and knowledge regarding the use of folic acid and its related benefits. Data analysis was carried out using SPSS v21 software. A P value < 0.05 was considered statistically significant. Results: In this study, the mean age of the participants was 30.73±6.77 years. About 49 (21.3%) women used folic acid supplements in the correct way. The mean score of women's knowledge was 6.20 ± 2.15. The minimum and maximum scores for knowledge were 1-10. There was a statistically significant relationship between taking folic acid with the subject's knowledge about folic acid (p=0.035), family income (p=0.027), women's job (p=0.046), education level (p=0.001) and the number of children (p=0.026). Conclusion: The study revealed that the status of taking folic acid among women and their knowledge concerning folic acid and its related importance were not satisfactory. This finding suggests that there is a need to give emphasis and deliver health education about preconception folic acid supplementation for women.

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 508.2-509
Author(s):  
K. Maatallah ◽  
H. Boussaa ◽  
H. Riahi ◽  
H. Ferjani ◽  
M. Habechi ◽  
...  

Background:Foot disease is a common problem in rheumatoid arthritis (RA). Therapeutic decisions are often based on clinical examination (CE) alone, which can be adversely affected by factors such as deformity, obesity, and peripheral edema. Ultrasonography (US) has previously been shown to be more sensitive than CE for detecting synovitis and tenosynovitis in RA forefeet, but few data exist for the hindfoot and ankle.Objectives:The aim of this study was to compare CE and US for the detection of hindfoot and ankle synovitis and tenosynovitis in patients with established RA.Methods:We conducted a cross-sectional study including patients with RA (ACR/EULAR 2010). Demographic data and disease parameters were collected. CE was performed by a rheumatologist for the presence or absence of tenderness, swelling, and mobility restriction of both ankles. The following tendons were examined for tenosynovitis: tibialis anterior (TA) and posterior (TP), fibularis longus (FL), and brevis (FB) (assessed together). In a second time, US examination of the tibiotalar, talonavicular, and subtalar joints and the same tendons as CE was performed by a blinded radiologist experienced in musculoskeletal imaging using a Philips HD11 device with a high-frequency linear transducer. The presence or absence of synovitis and tenosynovitis was recorded, and the composite synovitis score (power doppler / grayscale ultrasound (PDUS)) was measured for each joint. The US score of each patient was defined by the sum of the composite scores of the joints studied (0-30). A p-value <0.05 was considered significant.Results:Sixty-two feet were examined in 31 RA patients (25 women and six men) with a mean age of 54.8±10.8 years old [32-70]. The mean disease duration was 8.5±7.2 years [1-37]. Rheumatoid Factor (RF) and Anti-Citrullinated Peptides Antibodies (ACPA) were positive in 61.3% and 83.8% of cases. The mean DAS28 ESR was 3.8±1.5 [0.6-7].Clinical examination of ankles revealed tenderness in 57.4% of cases, swelling in 38.8% of cases, and restriction in the range of motion in 11.1% of cases. TA tenosynovitis was noted in 14.8% of cases, TP tenosynovitis in 22.2% of cases, and FL and FB tenosynovitis in 31.5% of cases.US showed tibiotalar synovitis in 59.3% of cases, talonavicular synovitis in 64.8% of cases, and subtalar synovitis in 46.3% of cases. TA tenosynovitis was noted in 5.6% of cases, TP tenosynovitis in 22.2% of cases, and FB and FL tenosynovitis in 25% and 11.1% of cases respectively.An association was found between clinical tenderness and US synovitis of the tibiotalar joint (p=0.013) and the talonavicular joint (p=0.027). No association was noted between clinical swelling and US synovitis in these joints.No association was noted between clinical and US tenosynovitis of TA (p=0.279), TP (p=0.436), FB (p=0.495) and FL (p=0.315).Conclusion:Clinical examination of RA ankles may be challenging and needs to be coupled with US, which is more sensitive and accurate in the detection of synovitis and tenosynovitis.Disclosure of Interests:None declared


2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Shakeel Ahmad ◽  
Rashida RIaz ◽  
Muhammad Haseeb ◽  
Hafiza Ammara Rasheed ◽  
Samia Iqbal

Purpose: To compare the mean difference of visual acuity as measured by auto refraction and subjective refraction. Study Design:  Descriptive cross-sectional study. Place and Duration of Study:  Department of ophthalmology, Services hospital Lahore from November 2013 to April 2014. Material and Methods:  Using non-probability consecutive sampling 300 eyes of 300 patients fulfilling inclusion criteria were recruited through OPD registration slip. Demographic data including age and gender was recorded. Complete ophthalmic examination was performed. This included measurement of refractive error by auto-refraction as well as subjective refraction. Detailed anterior segment examination with slit lamp and dilated fundus examination with indirect ophthalmoscopy was performed. The collected data was analyzed by using software SPSS version 17. Results:  The mean age of patients was 34.71 ± 7.45 years. There were 156 (52%) males and 144 (48%) females. There were 263 (87.69%) patients who had visual acuity of 6/6 and 37 (12.33%) had 6/9. Mean spherical auto-refraction and subjective refraction was 0.0290 ± 2.58 and -0.2842 ± 2.37 D with mean difference of -0.3133 ± 1.27 D. The mean cylindrical auto and subjective refraction in this study was -.9742 ± 0.78 D and -0.7500 ± 0.81 D and mean difference was 0.2242 ± 0.74 D. The mean cylindrical axis of auto and subjective refraction was 114.88 ± 49.75 and 115.60 ± 49.70 with mean difference as 0.72 ± 3.02 D (p-value < 0.05). Conclusion:  Difference of spherical, cylindrical and cylindrical axis in auto and subjective refraction was significantly different.


Author(s):  
Sajna M. V. ◽  
Shefaly Ann Jacob

Background: Anemia is one of the major problems among adolescents in India. As daily and once weekly supplementation of iron and folic acid show same effects in terms of growth rate, it has been decided that weekly supply is an effective method to tackle anaemia. The adherence to these tablets is an important factor to monitor the programme. Methods: A cross sectional study was conducted among the school students of 6-10th classes in Thrissur corporation area for a period of 6 months regarding the adherence to weekly iron and folic acid tablets. Sample size was calculated based on a pilot study and for a cluster sampling technology. After getting consent, data were collected, coded and analysed using SPSS17. Results: 380 students participated in the study. Mean age of the population was 13.01+ 1.3 years (with a range of 10 – 16 years). Only 139 (36.6%) students took tablets initially for a period of 1-2 months. Among the total girls, 124 (34.6%) took tablets initially. Of the students who took initially, 57 were continuing intake of iron tablets. The adherence to weekly iron and folic acid tablets for at in this study was 15% (n=57). Among the students who initially consumed tablets 36.6% reported stomach ache. Nausea (13.6%), vomiting (10.7%), black stool (9.3%), diarrhoea (5%) were other reported side effects of the drugs. Conclusions: The adherence to weekly iron and folic to this study was less. This can be effectively improved with continued health education sessions using different methods including the parents.


2021 ◽  
Vol 1 (2) ◽  
pp. 1-5
Author(s):  
Mona Ahmed Babiker Ahmed ◽  
Atif Elamin Abdelgadir ◽  
Hayfa Mohammed Ismail

This study was conducted to evaluate the level of adopted biosecurity measures in broiler farms based on manure bacterial load examination in Khartoum State, Sudan. To achieve the goal, a cross sectional study was conducted. Data and manure samples were collected from January to September 2018 from 12 close system broiler farms according to Non-probability Multistage Cluster Sampling Method in Khartoum, Khartoum North (Bahri), and Omdurman localities (4 for each). A standardized questionnaire was also conducted and used for data collection. A total of 12 manure samples were collected from one chosen broiler house in each farm to check the TVCs. All collected Data were subjected to descriptive and analytical statistic such as Chi square and ANOVA using SPSS. The Results of external biosecurity measures revealed that half of the total farms examined (50%) were at a distance between 500 m to 1km from the nearest poultry farm. The same percentage was obtained for no manure spreading from neighboring farms. However, frequent passage of other farms vehicles via near public road was reported in 50% of participating farms. The internal biosecurity results showed that all the examined farms (100%) prohibiting manure storage beside 75.0% of them remove the manure through the dirty area. Furthermore, workers protective wearing when contact waste and hygiene practicing after removing waste sometimes practiced by 75.0% of the participant farms. The mean of bacterial TVCs in manure samples was found below the cut-off level (6.01±0.78 cfu/g) with 95% confidence intervals of 4.48-7.37, 5.20-6.79, and 4.39-7.84 and mean TVC of 5.93±0.90, 6.00±0.50, and 6.11±1.08 cfu/g for Khartoum, Khartoum North, and Omdorman, respectively. No significant difference was obtained for log means of bacterial TVCs and farm location (F value=0.047 and P-value=0.955). In conclusion, despite that the bacterial counts in manure samples were below the cut-off level, poor hygienic practices were detected. Formulation of suitable procedures and regulations by official authorities for implementing biosecurity measures is recommended.


2020 ◽  
Author(s):  
Mohamed Hayir Tahlil Mohamud ◽  
Lul Mohamud Mohamed ◽  
Mohamed Ali Magan ◽  
Mohamed Abdulkadir Mohamud ◽  
Abdishakur Abdukadir Muse

Abstract Background: Immunization is amongst the most cost effective public health interventions for reducing global childhood morbidity and mortality. However globally 9 million deaths of children occur as a result of vaccine-preventable disease, a bigger proportion occurred in sub-Saharan Africa which was 4.4 million. Therefore, this study aimed to assess barriers for complete vaccination coverage among under five years children in Mogadishu, Somalia. Methods: A community based Cross-sectional study was conducted in between April to July, 2019 in Mogadishu-Somalia. Two-stage cluster sampling with systematic random sampling was used to select a sample of 820 households. Data was collected through structured, interviewer administrator questionnaire. In case more eligible children found at single selected household, one child was randomly selected and the information related to immunization was interviewed from his/her caregiver. Results: the overall, fully vaccinated under five years children was found to be 45.2%. Immunization was found to be increased by being a younger caregiver (β = -0.019, P-value=0.042), being married caregiver, being Father with Secondary & above education (AOR=1.755, 95% CI=1.161-2.655, P-value =0.008), being a young child (β = -0.018, P-value=0.011), being children from birth order of fifth & above (AOR=1.539, 95% CI=1.011-2.343, P-value=0.044), Married caregiver (AOR=0.244, 95% CI= 0.063-0.94, P-value=0.041), increased Household monthly family income= (β = 0.003, P-value=0.000), Availability of vaccine at the time of visit (AOR =6.147, 95% CI=1.943-19.441, P-value=0.002), Cost affordability of vaccine =( AOR =1.951, 95% CI=1.238-3.076, P-value=0.004), Being born at health facility (AOR =1.517, 95% CI=1.104-2.086, P-value=0.010), having good Knowledge on immunization (AOR =1.125, 95% CI=1.070-1.181, P-value=0.001), having good Practice on immunization (AOR =2.756, 95% CI=2.233-3.402, P-value=0.001) and having good Perception on vaccine (AOR =4.976, 95% CI=2.183-11.340, P-value =0.001).Conclusion: In conclusion, the result of this study has revealed that the proportion of fully vaccinated under five children in Mogadishu is very low. Steps to promote Health education and vaccine availability should be lounged.


2020 ◽  
Vol 6 (2) ◽  
pp. 74-77
Author(s):  
Mohammad Enayet Hussain ◽  
Bithi Debnath ◽  
AFM Al Masum Khan ◽  
Md Ferdous Mian ◽  
Md Nahidul Islam ◽  
...  

Background: The visual evoked potentials (VEP) is a valuable tool to document occult lesions of the central visual channels especially within the optic nerve. Objectives: The purpose of the present study was to observe the findings of first few cases of VEP done in the neurophysiology department of the National Institute of Neurosciences (NINS), Dhaka, Bangladesh. Methodology: This cross-sectional study was conducted in the Department of Neurophysiology at the National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from September 2017 to March 2020. All patients referred to the Neurophysiology Department of NINS for VEP were included. Pattern reversal VEPs were done using standard protocol set by International Federation of Clinical Neurophysiology (IFCN). Results: The mean age of the study population was 30.70 (±12.11) years (6-68 years) with 31 (46.3%) male and 36 (53.7%) female patients. The mean duration of illness was 8.71 (±1.78) months (3 days- 120 months). Most common presenting symptom was blurring of vision (37.3%) and dimness of vision (32.8%). Patterned VEP revealed mixed type (both demyelinating and axonal) of abnormality in most cases [29(43.35)]. The most common clinical diagnosis was multiple sclerosis (29.85%) and optic neuropathy (26.87%). In the clinically suspected cases of multiple sclerosis, optic neuropathy and optic neuritis most of the cases of VEP were abnormal and the p value is 0.04 in optic neuropathy and optic neuritis. Conclusion: The commonest presentation of the patients in this series were blurring of vision and dimness of vision. The most common clinical diagnosis for which VEP was asked for, was optic neuritis and multiple sclerosis. Most abnormalities were of mixed pattern (demyelinating and axonal). Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 74-77


2015 ◽  
Vol 59 (6) ◽  
pp. 3240-3245 ◽  
Author(s):  
Kanokrat Rungtivasuwan ◽  
Anchalee Avihingsanon ◽  
Narukjaporn Thammajaruk ◽  
Siwaporn Mitruk ◽  
David M. Burger ◽  
...  

ABSTRACTTenofovir (TFV) is eliminated by renal excretion, which is mediated through multidrug-resistant protein 2 (MRP2) and MRP4, encoded byABCC2andABCC4, respectively. Genetic polymorphisms of these transporters may affect the plasma concentrations of tenofovir. Therefore, the aim of this study was to investigate the influence of genetic and nongenetic factors on tenofovir plasma concentrations. A cross-sectional study was performed in Thai HIV-infected patients aged ≥18 years who had been receiving tenofovir disoproxil fumarate at 300 mg once daily for at least 6 months. A middose tenofovir plasma concentration was obtained. Multivariate analysis was performed to investigate whether there was an association between tenofovir plasma concentrations and demographic data, including age, sex, body weight, estimated glomerular filtration rate (eGFR), hepatitis B virus coinfection, hepatitis C virus coinfection, duration of tenofovir treatment, concomitant use of ritonavir-boosted protease inhibitors, and polymorphisms ofABCC2andABCC4. A total of 150 Thai HIV-infected patients were included. The mean age of the patients was 43.9 ± 7.2 years. The mean tenofovir plasma concentration was 100.3 ± 52.7 ng/ml. In multivariate analysis, a low body weight, a low eGFR, the concomitant use of ritonavir-boosted protease inhibitors, and theABCC44131T → G variation (genotype TG or GG) were independently associated with higher tenofovir plasma concentrations. After adjusting for weight, eGFR, and the concomitant use of ritonavir-boosted protease inhibitors, a 30% increase in the mean tenofovir plasma concentration was observed in patients having theABCC44131 TG or GG genotype. Both genetic and nongenetic factors affect tenofovir plasma concentrations. These factors should be considered when adjusting tenofovir dosage regimens to ensure the efficacy and safety of a drug. (This study has been registered at ClinicalTrials.gov under registration no. NCT01138241.)


2021 ◽  
Vol 18 ◽  
Author(s):  
Marwa Hammad ◽  
Huny Bakry

Background: Autoimmune inflammatory rheumatic diseases have long been treated by conventional disease-modifying anti-rheumatic drugs. Biological therapy is a new era in the treatment of rheumatic diseases, but satisfaction and adherence to it is still not well tested. Aim: To assess the satisfaction and adherence to biological treatment among patients with autoimmune inflammatory rheumatic diseases. Methods: A cross sectional study was conducted among 56 patients suffering from inflammatory rheumatic diseases using Morisky 8 questionnaire and Treatment Satisfaction Questionnaire for Medication (TSQM) over a period of one month Results: About 76.8% of the patients had medium adherence and the underlying cause of missing doses was the unavailability of the drugs. The mean satisfaction with biological treatment was 62.7±6.9. Patients who did not receive formal education had significantly higher satisfaction with the biological treatment than others 64.94±5.01 at a P value 0.04 (<0.05). Conclusion: Patients with inflammatory rheumatic diseases in our study showed medium adherence and satisfaction. Authorities in the medical field are providing great help to these patients in need of biological therapy, but ensuring the availability of all doses of the biological treatment regimen is still necessary. Patient, family and nurse education programs are also necessary to maximize adherence and satisfaction.


2021 ◽  
Author(s):  
Anas Shamala ◽  
Ebtesam Al-Maimooni ◽  
Salsbeel Al-Matari ◽  
Ryhana Hiyat ◽  
Mohammed Al-wesabi ◽  
...  

Abstract Backgrounds: The present study sought to assess tooth loss and oral hygiene practices among a sample of Yemeni women in association with giving births (parity).Subjects and Methods: This cross-sectional study included a sample of 644 Yemeni women. They were interviewed to gather socio-demographic (age, education, number of children) and behavioral data (oral hygiene practices, khat chewing and smoking). Additionally, they were examined clinically to assess number of tooth loss. Data were analyzed using SPSS with a P-value < 0.05 was considered statistically significant. Results: The participating women aged between 16 and 51 years. Only one fifth of the sample reported brushing their teeth regularly (i.e, at least once a day), and around 36.8% reported using dental aids occasionally. Additionally, 52% and 21% of the sample reported they were khat chewers and smokers, respectively. The mean number of tooth loss was 4.7. The mean number of children was 4.15, with approximately 54% of the participating women had more than 3 children. The results of the logistic regression revealed a significant association between number of children and tooth loss. Conclusion: Yemeni women had poor oral hygiene practices and high prevalence of tooth loss increased proportionally with the increased number of children. This emphasizes the importance of an effective oral hygiene motivation and health education among female patients during pregnancy periods.


2020 ◽  
Vol 7 (6) ◽  
pp. 997
Author(s):  
Dharmendra Jhavar ◽  
Neha Kirti ◽  
Sumit Kumar Vishwakarma ◽  
Umesh Kumar Chandra ◽  
Vinod Verma

Background: Since a long time ago, the experts have realized that determination of cut-off point for diagnosing diabetes will be revised over time with the lower blood glucose level as the more sensitive diagnosis for detecting the occurring complication and biochemical changes.Methods: This cross sectional study was carried out in the department of medicine, M.G.M. Medical College and M.Y. Hospital Indore from July, 2016 to August, 2017 in 200 individuals and patients having euglycemic status attending General Medicine OPD.Results: In the low and high normal group 2 (2.0%) and 8 (8.0%) were having abnormal total cholesterol (TC) level respectively. The mean total cholesterol in the low normal group was 117.16±26.94mg/dl and it was 154.74±28.38mg/dl in the high normal group. The difference was found to be statistically significant (p value 0.000). In the low and high normal group, 4 (4.0%) and 17 (17.0%) were having abnormal triglyceride (TG) levels respectively. The mean TG levels in the low and high normal group were 96.93±22.64mg/dl and 110.55±32.37mg/dl respectively. The difference was found to be statistically significant (p value 0.001). In the low and high normal group, 6 (6.0%) and 14 (14.0%) patient was having abnormal uric acid levels respectively. The mean uric acid levels in the low and high normal group was 4.88±1.10mg/dl and 5.31±1.31mg/dl respectively. The difference was found to be statistically significant (p value 0.013).Conclusions: Higher levels of Cholesterol and Triglycerides were found more commonly in high normal euglycemic group compared to low normal euglycemic group. Mean cholesterol and mean triglyceride levels were higher in high normal euglycemic group.


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