scholarly journals Comparative evaluation of the use of a chitosan-based multicomponent remedy in patients with acantholytic lesion of the tissues of the prosthetic bed to provide conditions for the use of removable dentures

2018 ◽  
Vol 24 (1) ◽  
Author(s):  
Bogdan Genyk

The article describes the offered by us multicomponent remedy based on chitosan, to provide analgesic and wound-healing effect in patients with acantholytic lesions of the prosthetic bed tissues. Objective of the study. To improve the conditions of removable dentures use for patients with acantholytic pemphigus. Materials and methods. The study involved 56 patients with acantholytic pemphigus, aged from 45 to 63 years old, who were divided into 2 clinical groups. The main group used the proposed remedy; the comparative group received the standard local pemphigus treatment. Methods for determining the area of ​​mucus lesion and the method for determining the intensity of pain syndrome were used to evaluate the final results. Results of the study and their discussion. The average value of visual analogue scale (VAS) was 4.76±0.56 cm in patients of the main group during the first day. During the 7th and 14th day, the value decreased to 2.4±0.28 cm and 1.87±0.12 cm, respectively. In patients of the comparison group, the average value of VAS was 5.07±0.36 cm as for the first day and 4.45±0.45 and 2.36±0.17 cm during the 7th and 14th days, respectively. The ratio of the mean value of the affected area in patients of the main group and the comparison group was 1.04 during the first day, and during the 7th and 14th day the area of ​​injury in patients of the main group was lower 1.29- and 1.84 -fold, respectively. Conclusions The results of the study confirm the necessity of using a multicomponent remedy based on chitosan together with the removable dentures in patients with acantholytic pemphigus, due to its clearly expressed epithelial and analgesic action.

2019 ◽  
Vol 16 (2) ◽  
pp. 225-229
Author(s):  
M. V. Pshenichnov ◽  
O. V. Kolenko ◽  
E. L. Sorokin ◽  
Ya. E. Pashentcev

Purpose. Revealing of the ocular risk factors in the formation of diabetic macular edema (ME) in type 2 diabetes mellitus (DM2).Patients and methods. A 3.5-year research of 80 patients (160 eyes) with DM2 without signs of ME at the beginning of the research was performed. The main group consisted of 46 patients with ME symptoms on one or both eyes during the research period, the comparison group included 34 patients without ME symptoms to the end of the research. The initial ocular characteristics were retrospect compared in groups.Results. The mean value of the axial lengths (AL) in the eyes of the main group was 23.12 ± 0.75 mm compared to 23.82 ± 0.62 mm in the comparison group (significant difference, p < 0.01). AL was less than 23.5 mm in 66 % of the eyes in the main group and only in 22 % of the eyes in the comparison group (p < 0.01). The mean value of the initial macular retina volume in the main group was significantly higher than in the comparison group — 7.51 ± 0.22 mm3 and 7.21 ± 0.12 mm3, respectively (p < 0.01). Initial background diabetic retinopathy (DR) was noted in 73 % of the eyes in the main group, which significantly differed from the comparison group, where this index was noted only in 13 % of the eyes (p < 0.01).Conclusion. Significant ocular risk factors for the formation of ME in patients with DM2 are: the initial macular retina volume more than 7.3 mm3, the value of the AL less than 23.5 mm; the initial background DR. The use of the detected morphometric parameters of eye and retina in combination with an adequate assessment of the risk factors in human organism makes it possible to assume with high degree of probability a high risk of the primary formation of diabetic ME in patients with DM2. 


2019 ◽  
Vol 16 (1) ◽  
pp. 63-69
Author(s):  
M. V. Pshenichnov ◽  
O. V. Kolenko ◽  
E. L. Sorokin ◽  
Yu. E. Pashentcev

Purpose. Revealing of the intraocular risk factors in the diabetic macular edema (ME) formatis in diabetes mellitus type II (DM2). Patients and methods. A 3.5-year research of 80 patients (160 eyes) with DM2 without signs of ME at the beginning of the research was performed. The main group consisted of 46 patients with ME symptoms on one or both eyes during the research period, the comparison group included 34 patients without ME symptoms to the end of the research. The initial ocular characteristics were retrospectively compared in groups.Results. The mean value of the axial lengths (AL) in the eyes of the main group was 23.12 ± 0.75 mm compared to 23.82 ± 0.62 mm in the comparison group (significant difference, p < 0.01). AL was less than 23.5 mm in 66 % eyes in the main group and only in 22 % of the eyes in the comparison group (p < 0.01). The mean value of the initial macular retina volume in the main group was significantly higher than in the comparison group — 7.51 ± 0.22 mm3 and 7.21 ± 0.12 mm3, respectively (p < 0.01). Initial background diabetic retinopathy (DR) was noted in 73 % eyes in the main group, which significantly differed from the comparison group, where this index was noted only in 13 % of the eyes (p < 0.01).Conclusion. Significant ocular risk factors for the formation of ME in patients with DM2 are: the initial macular retina volume more than 7.3 mm3, the value of the AL less than 23.5 mm; the initial background DR. The use of the detected morphometric parameters of eye and retina in combination with an adequate assessment of the risk factors in human organism makes it possible to assume a high risk of the primary formation of diabetic ME in patients with DM2 with high degree of probability.


2018 ◽  
Vol 25 (3) ◽  
Author(s):  
Bogdan Genyk

The recommendations, offered by us, as for the use of removable dentures in patients with acantholytic pemphigus using a multicomponent remedy based on chitosan are described in the article to provide an analgesic and wound-healing effect in patients with acantholytic damage of the prosthetic bed tissues.Objective of the study. To improve the conditions for the use of removable dentures for acantholytic pemphigus patients.Materials and methods. The study involved 56 patients with acantholytic pemphigus, aged 45 to 63 years old, who were divided into 2 clinical groups. The main group used removable dentures according to our recommendations; the comparison group used removable dentures in accordance with generally accepted recommendations. Methods for determining the intensity of the pain syndrome and the subjective responses of patients about the state of health were used to evaluate the ultimate results.Results of the research and their discussion. Improvement of general state according to the data of a subjective survey in the main group was observed in 20 patients, which was 71.42% during the 7th day; and in 27 patients during the 14th day, which was 96.42%. In the comparison group, patients who subjectively felt better were 35.71% during the 7th day and 57.14% during the 14th day, respectively.Conclusions. The results of the study confirm the necessity to develop, implement and improve the recommendations for the inclusion into the protocol of the use of removable orthopedic structures of dentures in patients with acantholytic lesions of the prosthetic bed tissues.


2011 ◽  
Vol 18 (4) ◽  
pp. 3-10
Author(s):  
A V Krut'ko ◽  
Shamil' Al'firovich Akhmet'yanov ◽  
D M Kozlov ◽  
A V Peleganchuk ◽  
A V Bulatov ◽  
...  

Results of randomized prospective study with participation of 94 patients aged from 20 to 70 years with monosegmental lumbar spine lesions are presented. Minimum invasive surgical interventions were performed in 55 patients from the main group. Control group consisted of 39 patients in whom decompressive-stabilizing operations via conventional posteromedian approach with skeletization of posterior segments of vertebral column were performed. Average size of operative wound in open interventions more than 10 times exceeded that size in minimum invasive interventions and made up 484 ± 56 and 36 ± 12 sq.cm, respectively. Mean blood loss was 326.6 ± 278.0 ml in the main group and 855.1 ± 512.0 ml in the comparative one. In the main group no one patient required substitution hemotransfusion, while in 13 patients from the comparative group donor erythrocytic mass and/or fresh-frozen plasma were used to eliminate the deficit of blood components. Intensity of pain syndrome in the zone of surgical intervention by visual analog scale in the main group was lower than in comparative group. In the main and comparative groups the duration of hospitalization made up 6.1 ± 2.7 and 9.7 ± 3.7 bed days, respectively. In no one patient from the main group complications in the zone of operative wound were noted. Three patients from the comparative group required secondary debridement and in 1 patient early deep operative wound suppuration was observed. Application of low invasive surgical techniques for the treatment of patients with degenerative lumbar spine lesions enabled to perform radical surgical treatment with minimal iatrogenic injury. The method possessed indubitable advantages over the conventional open operations especially intraoperatively and in early postoperative period.


2018 ◽  
Vol 14 (3-4) ◽  
pp. 74-79
Author(s):  
I.V. Kolosovych ◽  
B.H. Bezrodnyi ◽  
I.V. Hanol

Relevance. The article is devoted to the problem of diagnosis and treatment of acute biliary pancreatitis, which remains one of the most common surgical diseases of the abdominal cavity and accounts for 33.2% of the total number of patients with acute pancreatitis. Objective of the work is to improve the diagnosis and results of surgical treatment of patients with acute pancreatitis of biliary etiology. Materials and methods. The results of treatment of 264 patients with acute pancreatitis of biliary etiology are analyzed. Operative treatment was applied in 92 (34,8 %) patients: endoscopic operations were performed in 44 patients (16,7 %). Thus, in 10 (3,8 %) patients, endoscopic papilloprotectomy was performed with the auditory of the duct system and the extraction of concrements. In other cases, organo-preserving intervention was performed without disturbing the morphofunctional integrity of the sphincter apparatus of the duct system: the cannulation in 6 (2,3%) patients, mechanical (balloon) in 5 (1,9 %) cases, pharmacological (myogenic antispasmodic) dilatation of distal duct and a large duodenal papilla in 11 (4,2 %) patients. In residual choledocholithiasis, a technique of papillotomy under the control of choledochoscopy was proposed – 12 (4,54 %) patients. A comparative analysis of the effectiveness of the treatment of patients who used the "open" (comparative group) and noninvasive endoscopic interventions in the early disease (the main group) was performed. Results. So in the main group the length of stay in the hospital was 12±3,2 days, respectively, in the comparison group – 26±4,3 days. In 42 (95,4 %) patients who had undergone endoscopic surgery, a positive clinical effect, a rapid regress of the symptoms of acute pancreatitis was achieved. In two (4,5 %) patients in the main group, the course was complicated by the development of the abscess of the stuffing box, and puncture under ultrasound control was performed. In patients of the comparison group complications arose in 5 (41,6 %) patients, it is noteworthy that all of them had undergone operative interventions, which were limited only to the rehabilitation and drainage of the abdominal cavity, a stuffing box bag. The mortality rate among unopposed was 1,2 % (2 patients), and among the operated – 11,9 % (11 patients). Among prooperated patients who died, 81,8 % (9 people) were elderly patients. Conclusions. The use of minimally invasive endoscopic interventions in the early phase of the disease reduces the length of stay of patients in the hospital from 26±4,3 days (comparison group) to 12 3,2 days (main group) and the number of complications occurring by 37,1 % (P <0, 05). Application of the proposed method of papillotomy under the control of choledochoscopy makes it possible to reduce the risk of perforation of the wall of the duodenum with the development of peritonitis or retroperitoneal phlegmon by 1,2 % (P <0,05).


Author(s):  
Yusuf Nasirudin ◽  
Dewa Putu Gde Purwa Samatra ◽  
Wahyuddin ◽  
Susy Purnawati ◽  
Ni Made Linawati ◽  
...  

In the game of futsal, work of postural muscle balance needed to maintain the stability of the body for receiving the pass and put the ball into the other team's goal at the time of attack, changing the direction of movement quickly when returning to their respective positions and avoid of back disorder. This research is a form of experimental research that will test the effectiveness of the provision of trunk balance exercise is better than the strengthening of back exercises to improve muscle work balance of erector spine on futsal beginner players, in this study sample will be divided into two groups, the first group will be given trunk balance exercise to improve balance of erectorspine muscles work in futsal begginer players, the second group will be given back strengthening exercise to improve balance of erectorspine muscles work in futsal begginer players.This study was conducted for 6 weeks and the intervention performed 18 times during the study period. Samples measured by surface electromyography to measure work of right and left erector muscle by calculating the proportion of the work on the muscle, the measurement is performed at before the intervention and then intervention in accordance with the grouping which has been divided and then after completion of the intervention, the samples will be re-measured to obtain the value of the intervention.The results of the first group who has been given of trunk balance exercise shows the average value of the before treatment (83.82 ± 2.94) % and the mean value of the after treatment (96.74 ± 2.39) %, and in the second group who has been given strengthening back exercise shows the mean value of the before treatment (88.29 ± 1.89) % and the mean value after treatment (95.91 ± 1.75) %, with the probability value of both groups is 0.000 (p <0.05), and can be expressed there is a significant difference between both groups. In the fourth hypothesis test conducted comparative results of both groups, using independent samples t-test using mean value of the first and second groups, in the first group (12.92 ± 2.94) %, and the second group (7.61 ± 2.12) %, with a probability value 0.000 (p<0.05) and can be expressed in statistical analysis is no significant difference between both treatments were carried out and that means, giving trunk balance exercise is better than back strengthening exercise to improve balance of erector spine muscles work on futsal beginner players.


1959 ◽  
Vol 6 (2) ◽  
pp. 261-271 ◽  
Author(s):  
A. A. Townsend

To determine experimentally the mean value of a randomly fluctuating quantity, it may be necessary to measure the average value over a considerable interval of time. This problem arose in a recent study of the temperature fluctuations over a heated horizontal plate, and a system was used that depended on the counting of electrical pulses generated at a rate proportional to the quantity being measured. The advantage of this technique is that mean values may be measured over time intervals of almost unlimited length with little added difficulty for the experimenter. Circuits are described which measure: (a) the mean square of a fluctuating quantity and of its time-derivative, (b) the statistical distribution of the fluctuations, (c) the mean frequency of the fluctuation assuming a particular value, and (d) the mean product of two fluctuating quantities. Over the range of use, the stability and linearity of the calibrations is better than 1%, more than sufficient for work on natural convection. In its present form, the equipment responds uniformly to all frequencies below 100 c/s, but it would not be difficult to extend this range of response to higher frequencies.


2019 ◽  
Author(s):  
Eko Prasetyo

The research aims to measure the effect of entrepreneurial self-efficacy (ESE), entrepreneurial attitude (EA), and entrepreneurial intention (EI) towards entrepreneurship education. The research subjects were all students of SMK Negeri Tempursari. Research conducted is a population study with a total of 187 students. The research instrument used a questionnaire. Data analysis used the MANOVA technique. The results of the study were: (1) The mean value of the ESE, EA, and EI of students who have received entrepreneurship education is higher when compared to the average value of students who have not received entrepreneurship education; and (2) EA and EI have no significant effect between students who have received entrepreneurship education and students who have not received entrepreneurship education. While in the ESE aspect there is a significant influence between students who have received entrepreneurship education and students who have not received entrepreneurship education.


Author(s):  
Lena Susianti ◽  
Muhammad Anwar

This research was conducted to determine the effect of brainstorming strategies on students' creative thinking skills in workshop work subjects and technical drawing of class X students of Electronic Engineering at SMKN 1 Bukittinggi. The research design in this study is quasi-experimental. The instrument used was in the form of a matter of creative thinking skills tests that had been validated by an Expert, namely a lecturer majoring in Electronics Engineering. Validity test obtained the average value of validity of 0.85 which is in the valid category. Reliability test obtained Alpha Cronbach's value of 0.856 which is in the interpretation of the value of the pair very well. Because the questions are valid and reliable, the matter of creative thinking skills can be used. The results found the mean value in the experimental class (X TE1) 87.5 and the average value of the control class (X TE2) 74.0. After t-test, it was obtained that tcount> ttable so that Ha was accepted and Ho was rejected. It can be concluded that there is a significant influence on the application of brainstorming strategies to creative thinking skills.          Keywords: Creative Thinking Skills, Brainstorming Strategies, Validity, Reliability


Author(s):  
O. V. Avdeev ◽  
Y. K. Zmarko ◽  
A. B. Boykiv ◽  
R. O. Drevnitska

The high prevalence of inflammatory processes in the periodontitis of children, the ineffective effectiveness of preventive and curative measures can contribute to the development of generalized periodontitis, therefore it remains urgent to develop pathogenetic effects in the treatment of chronic catarrhal gingivitis.The aim of the study – a comparative assessment of the traditional treatment of chronic catarrhal gingivitis in children aged 6–7 years with therapy using an anti-inflammatory gel with neovitin.Materials and Methods. 61 children aged 6–7 years, suffering from chronic catarrhal gingivitis, were taken under clinical supervision and divided into groups: the main (30 children) and the comparative (31 children). All children underwent conventional therapy in accordance with the protocols for the provision of medical care – basic therapy. In the main group, for a month, pathogenetic agents were used: an anti-inflammatory gel with neovitin, hygiene products were recommended. In the comparative group, 3 % hydrogen peroxide solution was used for local therapy, for rinsing of the mouth (during the first week of treatment) – Rotokan, a therapeutic and prophylactic toothpaste.Examination and control examinations were carried out with the hygienic state of the mouth determined by the hygienic index of Yu. A. Fedorov and V. V. Volodkina, prevalence and intensity of the inflammatory process in the gums with the help of the Schiller-Pisarev test and the PMA index, oral fluid index (lysozyme content, formation of oxydradicals, urease activity, degree of dysbiosis, pH and viscosity).Results and Discussion. After the treatment, elimination of gum inflammation in patients of the main group was accompanied by a decrease in the PMA index by 3.8 times; formation of oxyradicals decreased in children of the main group by 6.35 %; in the comparative group – by 6.15 %. Urease activity decreased in children of the main group by 16.37 % (p<0.05), the viscosity of the oral fluid of children decreased in 2.65 times in the main group and in 2.13 times in the comparative group (p<0.05). The lysozyme content increased in children of the main group by 15.61 % (p<0.05) in the comparison group – by 9.63% (p<0.05). The treatment after 0.5 years caused an increase in the lysozyme content in the oral fluid of the children of the main group to the level of the control group. The degree of dysbiosis decreased in the main group, in the comparison group tended to increase.Conclusions. The use of the proposed therapy with gel with neovitin contributed to the best results of treatment: reducing the degree of inflammation of the gums, the number of visits to the doctor, improving the indices of nonspecific protection in the oral fluid of 6-7 years-old children and, to a greater extent, six months after the treatment.


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