FAKTOR PREDIKTOR GANGGUAN PENGLIHATAN BERAT DAN KEBUTAAN PADA PENDERITA DIABETES DI DAERAH ISTIMEWA YOGYAKARTA

Predictors of severe visual impairment and blindness among diabetic patients in Special Territory of YogyakartaPurposeThe purpose of this study was to identify any predictors of severe visual impairment and blindness among diabetic patients in Daerah Istimewa Yogyakarta.MethodsThis research was a cross-sectional study by analyzing registry data from (JOGED.COM). Data included sociodemographic characteristics, diabetic status, health record, and eye diseases. The analysis was done using chi-square and simple logistic regression tests follow with semi-partial correlation, stratification tests and multilevel analysis with Generalized Estimation Equation (GEE).ResultsAs much as 1093 data were included in this study. The prevalence of severe visual impairment was 12% and blindness was 6.5%. Cataract, diabetic retinopathy and diabetes duration >10 years were statistically significant with severe visual impairment and blindness while glaucoma and hypertension only significant with severe visual impairment. The contribution of cataract in severe visual impairment (4.73%) and blindness (3.11%) was highest among eye diseases. There was modification effect of cataract to severe visual impairment and blindness by diabetes duration. Based on GEE, cataract, diabetic retinopathy and diabetes duration > 10 years was the best model to predict the occurrence of severe visual impairment and blindness.ConclusionsPredictors of severe visual impairment and blindness among diabetic patients in Daerah Istimewa Yogyakarta were the cataract, diabetic retinopathy and diabetes duration >10 years. Modification effect of cataract by diabetes duration only was significant in a model to predict blindness.

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THE ASSOCIATION OF DIABETES DURATION WITH THE SEVERITY OF DIABETIC RETINOPATHY

DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) ◽

10.14710/dmj.v10i1.29942 ◽

2021 ◽

Vol 10 (1) ◽

pp. 64-68

Author(s):

Intan Lamy Manao ◽

Hesti Triwahyu Hutami ◽

Fifin Luthfia Rahmi ◽

Arnila Novitasari Saubig

Keyword(s):

Diabetic Retinopathy ◽

Diabetic Patient ◽

Microvascular Complications ◽

Diabetes Duration ◽

Diabetic Patients ◽

Research Subjects ◽

Chi Square ◽

Cross Sectional ◽

Duration Of Diabetes ◽

Chi Square Analysis

Background: The prevalence of diabetic patients is increasing over the years. It will increase the incidence of microvascular complications due to prolonged hyperglycemia in diabetic patient. Diabetic retinopathy is one of microvascular complication which is one of the leading causes of blindness in the world. Prolonged hyperglycemia in diabetic patient cause toxicity to the retina which cause nerve and vascular damage and death to the retina. In this study was analyzed the association of diabetes duration with the severity of diabetic retinopathy associated with many cases of delay in diagnosing diabetes recentlyObjective: This study aims to investigate the association of diabetes duration with the severity of diabetic retinopathyMethods: A cross-sectional design was performed by collecting data from the medical records of diabetic patients who were diagnosed with diabetic retinopathy in Diponegoro National Hospital in July-December 2019 using purposive sampling method. Research subjects were 51 patients who fulfilled the inclusion and exclusion criteria. The data were analyzed using non-parametric Chi Square test with p < 0.05 was considered statistically significant.Results: Prevalence was more in the age group of 51-60 years (45,1%), female (58,8%), diabetics <5 years (41,2%), and PDR (72,6%). Chi Square analysis shows no statistically significant association between duration of diabetes with the severity of diabetic retinopathy (p = 0,881)Conclusion: There was no statistically significant association between duration of diabetes with the severity of diabetic retinopathy

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Ocular morbidity among diabetics attending the preventive ophthalmic clinic of a tertiary care institute with special reference to diabetic retinopathy

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20194299 ◽

2019 ◽

Vol 7 (10) ◽

pp. 3722

Author(s):

Anjum B. Fazili ◽

Rohul J. Shah ◽

Mohd D. Mir ◽

Asif Jasmine ◽

Feroz A. Wani ◽

...

Keyword(s):

Risk Factors ◽

Diabetic Retinopathy ◽

Visual Impairment ◽

Tertiary Care ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Cross Sectional ◽

Care Institute ◽

Life Threatening ◽

One Year

Background: Non communicable diseases have taken over previously life threatening infections in the demographic transition. As the burden of NCDs including diabetes is increasing at an alarming rate the complications related to these diseases are also increasing leading to huge morbidity. Likewise, blindness/ visual impairment due to diabetic retinopathy is now slowly and steadily replacing refractive errors and cataracts as a cause of morbidity.Methods: This cross sectional study was carried over a period of one year in an ophthalmic unit of a tertiary health care institute in which known diabetic patients were screened for diabetic retinopathy besides various modifiable and non-modifiable risk factors.Results: Overall prevalence of diabetic retinopathy in our study population was found to be 29.0%. Among various risk factors duration of diabetes, hypertension, HbA1C >6.5% and serum creatinine >1.1 mg/dl were found to be significantly associated with diabetic retinopathy.Conclusion: Regular screening for diabetic retinopathy besides prevention and strict control of risk factors is key to prevention and progression of blindness/ visual impairment due to diabetic retinopathy.

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The impact of diabetes on visual acuity in Ethiopia, 2021

PLoS ONE ◽

10.1371/journal.pone.0256145 ◽

2021 ◽

Vol 16 (8) ◽

pp. e0256145

Author(s):

Mulu Tiruneh Asemu ◽

Mengesha Assefa Ahunie

Keyword(s):

Diabetic Retinopathy ◽

Visual Impairment ◽

Multinomial Logistic Regression ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Ischemic Optic Neuropathy ◽

Cross Sectional ◽

The Right ◽

The University ◽

The Impact

Background Diabetes mellitus is a complex metabolic disorder characterized by hyperglycemia that results from defects in insulin secretion, insulin action, or both. Glaucoma is the ocular complication of diabetic illness. In addition to this, retinopathy, maculopathy, ischemic optic neuropathy, extra-ocular muscle palsy, iridocyclitis, and rubeosis iridis were other complications. This study aims to determine the impact of diabetes on visual impairment and blindness among diabetic patients in Ethiopia. Methods This hospital-based cross-sectional study includes 401 samples of diabetic patients in the University of Gondar Comprehensive Specialized Hospital from January 2017 to January 2019. The multinomial logistic regression model was employed to identify significant differences among the factor variables. Results The magnitude of blindness was 32.17%, and the burden of severe visual impairment was 12.46%. Of the total patients, 120(29.9%) were have diabetic retinopathy of whom, 113(94.2%) were blind either in the right, left, or both eyes and 3 (2.5%) had severe visual impairment. One hundred twenty-six (31.42%) patients developed diabetic maculopathy of whom, 117 (92.85%) were blind either in the right or left eye, and one (0.8%) had severe visual impairment. From the whole diabetic patients, the magnitude of glaucoma was 186(46.38%), and from the patients who developed glaucoma was blind visual impairment 127(68.27%) either in the right or left eye. Thirty-eight (20.34%) had severe visual impairment. Glaucoma was significantly associated with severe visual impairment and blindness (p<0.001). Glaucoma, diabetic retinopathy, maculopathy, and type of diabetes are factors for visual impairment. Conclusion We found that visual impairment in the category of severe and blindness are frequent in Ethiopian diabetic patients. Glaucoma, diabetic retinopathy, maculopathy are the main predictive factors that determine the occurrence of blindness.

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Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study

Medical Sciences ◽

10.3390/medsci6040104 ◽

2018 ◽

Vol 6 (4) ◽

pp. 104 ◽

Cited By ~ 1

Author(s):

Veena H. R. ◽

Sribhargava Natesh ◽

Sudhir Patil

Keyword(s):

Diabetic Retinopathy ◽

Serum Creatinine ◽

Glycated Haemoglobin ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Chronic Inflammatory Condition ◽

The Mean

Periodontal disease (PD), a chronic inflammatory condition characterized by destruction of the supporting tissues of the teeth, increases the risk of complications in diabetics. Diabetic retinopathy (DR) is a microvascular complication of prolonged hyperglycaemia. There appears to be a similarity in the pathogenesis of DR and PD. Hence, this study aimed to investigate the association, if any, between DR and PD, correlate the severity of DR with the severity of PD, and investigate the association between glycated haemoglobin (HbA1c), serum creatinine and periodontal variables. The periodontal status of 200 adult diabetic patients in the age group of 30–65 years with varying severity of DR was assessed. Evaluation of the severity of PD was assessed by recording clinical parameters. Haematological investigations including glycated haemoglobin (HbA1c) and serum creatinine were estimated before the initiation of treatment for DR. A statistically significant association between the mean duration of diabetes mellitus (DM) and the severity of DR and PD was found. The severity of PD was directly correlated with the severity of DR. There was a significant association between the levels of HbA1c and serum creatinine and severity of DR and PD. There could be a plausible relationship between DR and PD. Further prospective studies on a larger population with longer follow-ups are required to ascertain whether PD and its severity directly affect the progression and severity of DR.

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DOES INSULIN LIKE GROWTH FACTOR-1 (IGF-1) DEFICIENCY HAVE A “PROTECTIVE” ROLE IN THE DEVELOPMENT OF DIABETIC RETINOPATHY IN THALASSEMIA MAJOR PATIENTS?

Mediterranean Journal of Hematology and Infectious Diseases ◽

10.4084/mjhid.2015.038 ◽

2015 ◽

Vol 7 ◽

pp. e2015038 ◽

Cited By ~ 4

Author(s):

Vincenzo De Sanctis

Keyword(s):

Diabetic Retinopathy ◽

Growth Factor ◽

Cross Sectional Study ◽

Protective Role ◽

Dependent Diabetes Mellitus ◽

Diabetic Patients ◽

Italian Population ◽

Sectional Study ◽

Cross Sectional ◽

Number Of Patients

Objective: This cross-sectional study was designed to give insights into relationship between Insulin-Growth-Factor 1 (IGF-1) levels and diabetic retinopathy (DR) in a sample of thalassaemia major(TM) patients with insulin dependent diabetes mellitus (IDDM). Τhis relation was not previously evaluated, despite the fact that both diseases co-exist in the same patient. The study also describes the clinical and biochemical profile of the associated complications in TM patients with and without IDDM. Design: A population-based cross-sectional study. Participants:The study includes 19 consecutive TM patients with IDDM and 31 age- and sex-matched TM patients without IDDM who visited our out-patient clinics for an endocrine assessment Methods: An extensive medical history, with data on associated complications and current medications, was obtained. Blood samples were drawn in the morning after an overnight fast to measure the serum concentrations of IGF-1, glucose, fructosamine , free thyroxine (FT4), thyrotropin (TSH) and biochemical analysis . Serologic screening assays for hepatitis C virus seropositivity (HCVab and HCV-RNA) were also evaluated, applying routine laboratory methods.Plasma total IGF-1 was measured by a chemiluminescent immunometric assay (CLIA) method. Ophthalmology evaluation was done by the same researcher using stereoscopic fundus biomicroscopy through dilated pupils. DR was graded using the scale developed by the Global Diabetic Retinopathy Group. Iron stores were assessed by direct and indirect methods. Results:Eighteen TM patients with IDDM (94.7 %) and 10 non-diabetic patients (32.2 %) had IGF-1 levels below the 2.5th percentile of the normal values for the Italian population. The mean serum IGF-1 concentrations were significantly lower in the diabetic versus the non-diabetic TM groups (p < 0.001). DR was present in in 4 (21 %) of 19 TM patients with IDDM and was associated with the main classical risk factors, namely inefficient glycemic control and duration of disease but not hypertension. Using the scale developed by the Global Diabetic Retinopathy Group, the DR in our patients was classified as non proliferative diabetic retinopathy (NPDR). Only few numbers of microaneurysms [1-3] were detected. Our data also confirm the strong association of IDDM in TM patients with other endocrine and non-endocrine complications.Conclusions: These results , although on a small number of patients, suggest a possible ‘protective’ role of low IGF-1 in the development of DR in TM patients

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Association of Retinopathy with Chronic Kidney Disease in Diabetes Mellitus

BIRDEM Medical Journal ◽

10.3329/birdem.v8i3.38123 ◽

2018 ◽

Vol 8 (3) ◽

pp. 210-214

Author(s):

Rushda Sharmin Binte Rouf ◽

SM Ashrafuzzaman ◽

Zafar Ahmed Latif

Keyword(s):

Diabetes Mellitus ◽

Chronic Kidney Disease ◽

Diabetic Retinopathy ◽

Kidney Disease ◽

Strong Association ◽

Albumin Excretion Rate ◽

Cross Sectional Study ◽

Fundus Photography ◽

Diabetic Patients ◽

Cross Sectional

Background: Diabetic retinopathy (DR) and nephropathy are two major complications of diabetes mellitus carrying significant morbidity and mortality. In this study DR was investigated in different stages of chronic kidney disease (CKD) to find out possible association of these two devastating complications.Methods: This cross-sectional study was conducted in 150 diabetic patients having CKD in BIRDEM. CKD was defined as estimated glomerular filtration rate (eGFR) of <60ml/min/1.73m2and/or urinary albumin excretion rate (UAER) >30 mg/day in at least two occasions in 3 months apart. Retinopathy was assessed by direct fundoscopic examination and confirmed by color fundus photography. Severe DR (SDR) included proliferative diabetic retinopathy, severe non-proliferative DR and maculopathy; whereas microaneurysm regarded as non-severe retinopathy.Results: Majority (68%) of the respondents had some form of retinopathy (38.35% SDR and 29.65% nonsevere). There was strong association between different levels of albuminuria (UAER) and DR (p<0.0001). On the contrary DR did not correspond with stages of CKD (P=0.349). Hypertension (79.5%) and dyslipidaemia (59%) were common co-morbidities.Conclusion: This study concluded that DR prevalence was more in nephropathy along with significant association with UAER. Whereas different stages of CKD was not associated with stages of DR . This finding focused the necessity of regular retinal examination irrespective of the stage of renal involvement.Birdem Med J 2018; 8(3): 210-214

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Detecting chronic kidney disease in diabetic adults by estimating glomerular filtration rate and Serum Creatinine

Journal of Contemporary Medical Sciences ◽

10.22317/jcms.v7i1.926 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Ahmed Kh. Mohammed Almaawi

Keyword(s):

Risk Factors ◽

Serum Creatinine ◽

Cross Sectional Study ◽

P Value ◽

Diabetic Patients ◽

Kappa Index ◽

Chi Square ◽

Cross Sectional ◽

Female Ratio ◽

Qualitative Variables

Objective: To assess CKD prevalence and risk factors including socio-demography among diabetics by estimating GFR rather than serum creatinine (sCr). Methods: A cross-sectional study was conducted in Dec. 15 2019 through Aug. 15 2020, among 800 diabetics attending tertiary diabetes centers, Baghdad. Data was collected by self-administered questionnaire. SPSS was used for data analysis by (mean, standard deviation and T-test) for quantitative variables and (frequency, percentage, Chi-square test and Kappa index) for qualitative variables. P-Value less than 0.05 was considered significant. Results: 800 diabetics for last 5-40 years, 95.6% with type2. Aged 52.1±13.2 years, with male: female ratio 1.03:1, 63.6% were with no income, sCr level was 0.86±0.3 mg/dl, and eGFR by Cockcroft Gault (CG) and CKD-EPI equations was 100.4±36.5 & 92.2±25.5 ml/min/1.73m2 respectively. CKD prevalence based on sCr, and eGFR assessed by above equations was 13.3%, 20% and 15.9% respectively (p<0.001). Those with CKD were hypertensive, females, and living in peripheries. Conclusions: Diabetic patients, mainly those with risk factors are more likely to develop CKD. It is better to detect CKD intially by estimating the GFR, rather than serum creatinine level alone. Furthermore, using CKD-EPI equation might be better than the CG formula to estimate the GFR.

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Sex-Gender Differences in Diabetic Retinopathy

Diabetology ◽

10.3390/ijd1010001 ◽

2020 ◽

Vol 1 (1) ◽

pp. 1-10

Author(s):

Sara Cherchi ◽

Alfonso Gigante ◽

Maria Anna Spanu ◽

Pierpaolo Contini ◽

Gisella Meloni ◽

...

Keyword(s):

Diabetic Retinopathy ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Sectional Study ◽

Type 2 Diabetic Patients ◽

Cross Sectional ◽

Large Sample ◽

Male Sex ◽

Type 2 Diabetic

Diabetic retinopathy (DR) is one of the main causes of visual loss in individuals aged 20–64 years old. The aim of this study was to investigate, in a multicenter retrospective cross-sectional study, sex-gender difference in DR in a large sample of type 2 diabetic patients (T2DM). 20,611 T2DM regularly attending the units for the last three years were classified as having: (a) No DR (NDR), (b) nonproliferative DR (NPDR), or (c) preproliferative/proliferative DR (PPDR). DR of all grades was present in 4294 T2DM (20.8%), with a significant higher prevalence in men as compared to women (22.0% vs. 19.3% p < 0.0001). Among DR patients, both NPDR and PPDR were significantly more prevalent in men vs. women (p = 0.001 and p = 0.0016, respectively). Women had similar age and BMI, but longer diabetes duration, worse glycemic metabolic control, and more prevalence of hypertension and chronic renal failure (CRF) of any grade vs. men. No significant differences between sexes were evident in term of drug therapy for diabetes and associate pathologies. Conclusions: In this large sample of T2DM, men show higher prevalence of DR vs. women, in spite of less represented risk factors, suggesting that male sex per se might be a risk factor for DR development.

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Oculo-Visual Findings among Industrial Mine Workers at Goldfields Ghana Limited, Tarkwa

Ophthalmology and Eye Diseases ◽

10.4137/oed.s9204 ◽

2012 ◽

Vol 4 ◽

pp. OED.S9204 ◽

Cited By ~ 2

Author(s):

GO Ovenseri-Ogbomo ◽

S Ocansey ◽

EK Abu ◽

S Kyei ◽

SB Boadi-Kusi

Keyword(s):

Visual Impairment ◽

Demographic Data ◽

Cross Sectional Study ◽

Eye Diseases ◽

Sectional Study ◽

Cross Sectional ◽

Visual Status ◽

Study Population ◽

The Mean ◽

Mine Workers

Objective The focus of this study was to evaluate the visual status of mine workers who were directly involved in mining and/or are exposed to the mining environment. Methods A hospital based cross-sectional study was conducted. Four hundred and six (406) workers were conveniently sampled for the study. Information on their socio-demographic data was also collected. In addition, all participants underwent ophthalmic examination. Results The mean age of the workers was 41.1 years. Visual impairment was found in 114 (28.1%) of the study population of which refractive error (56.8%) was the major cause. Presbyopia was also observed in 45.5% of the workers with only 30.3% of them wearing near correction. The prevalence of eye diseases were pterygium/pingueculae (25.8%), conjunctivitis (26.8%), suspected glaucoma (15.3%), and cataract (7.4%). Conclusions Visual impairment and eye diseases were found among the miners.

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Prevalence of Metabolic Syndrome in individuals with Type 2 Diabetes Mellitus

Revista Brasileira de Enfermagem ◽

10.1590/0034-7167-2016-0145 ◽

2017 ◽

Vol 70 (2) ◽

pp. 265-270 ◽

Cited By ~ 8

Author(s):

José Cláudio Garcia Lira Neto ◽

Mayra de Almeida Xavier ◽

José Wicto Pereira Borges ◽

Márcio Flávio Moura de Araújo ◽

Marta Maria Coelho Damasceno ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Metabolic Syndrome ◽

Type 2 Diabetes Mellitus ◽

Descriptive Analysis ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Chi Square ◽

Cross Sectional

ABSTRACT Objective: to identify the prevalence of Metabolic Syndrome and its components in a population of patients with type 2 Diabetes Mellitus. Method: a cross-sectional study was conducted with 201 diabetic patients. A descriptive analysis and Chi-square and Fisher's exact tests ( p <0.05) were performed. Results: the majority of participants were females and overweight, with a mean age of 63.1 years and a low level of education, and categorized as physically inactive. Of all individuals investigated, 50.7% were diagnosed with Metabolic Syndrome and 92% had at least one of the syndrome components with values beyond those recommended. Conclusion: it is essential to take preventive actions and develop studies that help to identify the factors associated with this syndrome.

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