A PROSPECTIVE STUDY OF THE PATTERN OF USE OF ANTIMICROBIAL AGENTS IN SURGICAL PROPHYLAXIS IN A TERTIARY CARE CENTRE

Objective: To evaluate the most common class of antimicrobial agents used in surgical prophylaxis. To evaluate the timing, dosage, route and duration of use of antimicrobial agents in surgical prophylaxis.Methods: The study subjects were 214 patients who underwent general surgical procedures at Vinayaka Missions Kirupananda Variyar Medical College from July 2013 to June 2014. The use of antimicrobial agents was noted from the first dose of antibiotic given before the induction of anaesthesia. After surgery was completed the duration of antibiotic in the post-operative ward was noted. Results: Majority of the patients were males of age group 50-60 y and the most common surgical procedure was hernioplasty. Combination therapy with two antimicrobial agents was more preferred regimen 126 (58.9%). Among the antimicrobial agent's cefotaxime 114 (24.8%) was the most commonly prescribed drug and it was followed by metronidazole 121 (21.9%). ceftriaxone 60 (13.1%) was the third most commonly prescribed antimicrobial agent. The mean duration of prescription of antimicrobial agents in the present study was 4.78 d and the mean cost of drug treatment was 787.54 rupees. The cost-effective regimen was that of aminoglycosides and imidazole.Conclusion: The choice of antimicrobial agent was based on the local prevalence pattern of microorganisms. The intravenous administration of antibiotic prophylaxis immediately before or after the induction of anaesthesia is the most reliable method for ensuring effective serum concentration at the time of surgery. The antimicrobial agent chosen must cover all the most likely contaminating organisms.

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Magnitude of hypothyroidism among patients of cholelithiasis in a tertiary care centre in rural West Bengal: a prospective study

International Surgery Journal ◽

10.18203/2349-2902.isj20214374 ◽

2021 ◽

Vol 8 (11) ◽

pp. 3375

Author(s):

Jaganmoy Maji ◽

Debjyoti Mandal

Keyword(s):

Stone Formation ◽

Tertiary Care ◽

Gall Stone ◽

Sampling Technique ◽

Cross Sectional Study ◽

Tertiary Care Centre ◽

Cross Sectional ◽

Medical College ◽

Elder Patients ◽

A Prospective Study

Background: Cholelithiasis is a common pathology of the gall bladder affecting about 10 to 15% of the adults in western countries and 2 to 29% in India. More than 80% of the patients with cholelithiasis are asymptomatic. Hypothyroidism may cause gall stone formation due to the hyperlipidemia, motility disorders affecting the bile duct and sphincter of Oddi.Methods: This was a descriptive cross-sectional study conducted at Department of Surgery, Bankura Sammilani Medical College and Hospital, Bankura from March 2019 to February 2020 for duration of one and half year. The sample size was 54 and consecutive non-probability sampling technique was used for the sampling. All the collected data were recorded in a pre-designed proforma and analyzed in MS excel.Results: Out of 54-patients with cholelithiasis, 28% patients were from the age group 45-54 years.40% patients were hypothyroid pre-dominantly females. Among 30-female patients 11 (26.82%) were hypothyroid and among 11-male patients 2 (15.38%) were hypothyroid. Hypothyroidism in male and female was statistically significant.Conclusions: This study was introduced to determine the relationship between hypothyroidism and cholelithiasis. It was concluded that hypothyroidism was more common in female, obese and elder patients. The gender distribution of the hypothyroidism in patients with cholelithiasis was statistically significant while all other variables were statistically not significant.

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A PROSPECTIVE HISTOPATHOLOGICAL STUDY OF MENINGIOMAS IN A TERTIARY CARE CENTRE OF VIJAYAWADA

10.36106/gjra/9100428 ◽

2021 ◽

pp. 11-13

Author(s):

C.Bhanu Sree ◽

P. Annapurna ◽

M. Rajani

Keyword(s):

Surgical Resection ◽

Tertiary Care ◽

Histopathological Study ◽

Age Group ◽

Care Centre ◽

Tertiary Care Centre ◽

Medical College ◽

Histological Appearance ◽

Classi Cation ◽

A Prospective Study

Background: Meningiomas are neoplasms arising from the arachnoidal cap cells in the meningeal coverings of the spinal cord and brain. These are the most common benign intracranial tumours and account for about 13-26% of all primary brain neoplasms. These are generally benign neoplasms of adults most often seen in middle age, but about 10% are atypical or malignant. These neoplasms are graded by WHO as Grade I , II and III . Benign meningiomas can be cured by surgical resection where as higher grade meningiomas require radiotherapy after surgical resection as these higher grade meningiomas have greater recurrence and aggressive behavior. Aims and Objectives: To study the variants and histopathological spectrum of meningioma and prognosis of variants. Material & Methods: The present study is a prospective study conducted in the department of Pathology, Siddhartha medical college from June 2019-May 2020. During this study, 16 cases of meningiomas were diagnosed and reviewed. Result:In our study of 16 cases females were 62.5%. The most common age group is 41-60 yrs (68.75%). Most common variant was noted to be transitional meningioma followed by meningothelial meningioma. Out of the 16 cases, grade I were 81.25%. Conclusion: Meningiomas account for 28-30% of primary central nervous system tumors and unveil a heterogeneous histopathology. The histological appearance of meningioma determines the grading for the management of the various subtypes and also associated with patient's prognosis. Hence a continuous revision of histopathological classication systems is required to improve the diagnostic accuracy. Benign meningiomas are the most common type. From our study, we conclude that transitional meningioma is the most common benign variant.

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Position of parotid papilla and commissure of lip in relation to maxillary occlusal plane among patients visiting a tertiary care centre of Nepal

Journal of Nepalese Prosthodontic Society ◽

10.3126/jnprossoc.v4i1.42303 ◽

2021 ◽

Vol 4 (1) ◽

pp. 1-6

Author(s):

P Mehta ◽

S Chhetri

Keyword(s):

Tertiary Care ◽

Cross Sectional Study ◽

Occlusal Plane ◽

Sectional Study ◽

Tertiary Care Centre ◽

Cross Sectional ◽

Medical College ◽

Exact Position ◽

The Mean ◽

Edentulous Patients

Introduction: The exact position of the Parotid papilla and commissure of the lip plays a crucial role in determining the maxillary occlusal plane which directly facilitates rehabilitating edentulous patients with a removable complete denture. Since the beginning, many authors have conducted different studies regarding its position but multiple variations in its location have been noted. Also, this type of study has not been conducted in the Nepalese population which drags the urge to determine the position of these soft-tissue landmarks in context to the Nepalese population. Objective: To determine the position of parotid papilla and commissure of lip in relation to the maxillary occlusal plane. Materials and Methods: A descriptive cross-sectional study was conducted in the 45 dentate subjects visiting Nobel medical college from November 2019 to April 2020. A vestibular impression was made, stone index fabricated and vernier caliper was used to locate position of parotid papilla & commissure of lip. All the data were collected and statistically analyzed. Results: The mean measurement of distances between maxillary occlusal plane and parotid papilla was 3.69 ± 1.19 mm and between maxillary occlusal plane and commissure of lip was 0.41 ± 0.83 mm respectively. Conclusion: This study showed that the position of the parotid papilla was superior to the position of the maxillary occlusal plane with a mean distance of 3.69mm. The commissure of lip was found to be at the level of maxillary occlusion plane in highest number of cases followed by a superior position with least at the inferior position with respect to the maxillary occlusal plane.

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A Study on the Clinicopathological Profile of the Cases of Colorectal Carcinoma

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i58b34229 ◽

2021 ◽

pp. 493-500

Author(s):

Dhanya Menon ◽

Iniya Sudhan ◽

Ganthimathy Sekhar

Keyword(s):

Colorectal Cancer ◽

Colorectal Carcinoma ◽

Sampling Method ◽

Tertiary Care ◽

Tumour Site ◽

Tertiary Care Centre ◽

Medical College ◽

Female Predominance ◽

Clinicopathological Profile ◽

The Mean

Aim: To assess the clinicopathological details of patients with colorectal cancer in a tertiary care centre in India and compare it other studies reported in the literature. Study Design: This is a retrospective study conducted on all the patients who were admitted in the period of 2017 to 2020. Place and Duration of Study: Department of Pathology, Saveetha Medical College, Thandalam, Chennai. The data was processed and the manuscript was prepared between June 2020 and January 2021. Methodology: Patient details were collected from the histopathology records and the parameters studied were age, gender, tumour site, histological type, differentiation and tumour stage of the colorectal carcinoma. The sampling was done using the complete enumerate sampling method. The patients diagnosed histopathologically as colorectal carcinoma were included in our study. Results: A total of 51 patients had been admitted in the years 2017, 2018, and 2019 in our institute. There was a female predominance among the patients. The mean age of the patients was lesser than the mean age of colorectal cancer cases in other studies which have been reported in the country. The most common tumour site was rectum in both the sexes and the most common histologic type was adenocarcinoma. The most common histological differentiation was moderate differentiation. Conclusion: The increased incidence in younger patients as compared to previous studies may be attributable to the lifestyle and dietary changes.

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Role of diagnostic hystero-laparoscopy in the evaluation of female infertility

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193528 ◽

2019 ◽

Vol 8 (8) ◽

pp. 3156

Author(s):

Deepa Shanmugham ◽

Nambala Divya Sahitya ◽

Sindhu Natarajan ◽

Deepak Kannan Saravanany

Keyword(s):

Tertiary Care ◽

Reproductive Age ◽

Polycystic Ovaries ◽

Tertiary Care Centre ◽

Male Factor ◽

Acute Pelvic Inflammatory Disease ◽

Tubal Factor ◽

The Mean ◽

A Prospective Study

Background: Infertility affects about 10-15% of reproductive age couples. The main causes of infertility include male factor, ovulatory disorders, tubal factor and endometriosis. This study was conducted to determine the role of Diagnostic hystero-laparoscopy (DHL) in the evaluation of female infertility.Methods: This study was a prospective study done in a tertiary care centre over a period of 1 year on all infertile couples. The exclusion criteria: male factor infertility, hypothyroidism, hyperprolactinemia, acute pelvic inflammatory disease. Diagnostic hysterolaparoscopy was performed in all study patients in pre ovulatory phase, under general anaesthesia. The findings were then documented and analysed.Results: A total number of 90 patients were recruited for the study. The mean age of the patients was 28±3 years. The mean BMI of the study patients was 25±4 kg/m2. The mean duration of infertility was 5.4 years. On laparoscopy, 28 patients had polycystic ovaries (31.1%), 4 patients had pelvic adhesions (4.4%), 2 patients had endometriosis (2.2%) and tubal block was identified in 10 patients (11.11%). 10 patients had abnormal findings on hysteroscopy.Conclusions: Hystero laparoscopy is an effective diagnostic tool in the evaluation of infertility and has to be included in basic diagnostic workup.

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Study of benign neck swellings of anterior neck triangle at a tertiary care centre

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20192709 ◽

2019 ◽

Vol 5 (4) ◽

pp. 941 ◽

Cited By ~ 1

Author(s):

Pradipkumar Digambar Khokle ◽

Vinod Tukaram Kandakure ◽

Ujjwala Madhukar Kolekar

Keyword(s):

Tertiary Care ◽

Surgical Excision ◽

Lateral Neck ◽

Neck Swelling ◽

Thyroglossal Cyst ◽

Tertiary Care Centre ◽

Medical College ◽

Wide Range ◽

Thyroid Swelling ◽

A Prospective Study

Background: Tumors of the neck are interesting to surgeons especially because of the complex neck anatomy and difficult differential diagnosis. The aim is to study different types of neck swellings i.e. thyroid swelling, salivary gland swelling, other neck swellings such as thyroglossal cyst, branchial cyst, lymphangioma and also the miscellaneous and rare lumps in the neck. The study also discusses their age and sex-wise distribution, clinical features, presentation, diagnostic modalities and treatment.Methods: This is a prospective study, conducted at our institute Government Medical College, Latur from June 2017 to May 2018 for a duration of one year. Results: A total of 57 patients were studied during this period. Out of the 57 patients, 47 of them were midline swellings (82.45%) and 10 among them were lateral neck swellings (17.55%). People over a wide range of age group between 5-60 years were affected. Midline neck swelling were more common than lateral neck swellings.Conclusions: Among the midline benign neck swellings, thyroid swelling was found to be the commonest followed by thyroglossal cyst. Thyroid swellings occur more commonly in the females than males. Ultrasound guided FNAC is the most common, effective and safe investigation that aids in the diagnosis. Treatment of choice for benign, non-inflammatory and non-malignant neck swelling is mostly surgical excision rather than medical management.

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When the Disease is Known but the Patient is not. Outcome of 118 such Patients at a Tertiary Care Centre

Romanian Neurosurgery ◽

10.2478/romneu-2018-0066 ◽

2018 ◽

Vol 32 (2) ◽

pp. 505-512

Author(s):

Gaurav Jaiswal ◽

Praveen Kumar Tripathi ◽

Vardan Kulshreshtha ◽

Tarun Kumar Gupta

Keyword(s):

Head Injury ◽

Road Traffic ◽

Tertiary Care ◽

Good Recovery ◽

Tertiary Care Centre ◽

Medical College ◽

Discharged Patients ◽

History Of ◽

A Prospective Study ◽

Lost To Follow Up

Abstract This is a prospective study, carried out at the Department of Neurosurgery at M.B.G Hospital, R.N.T Medical College, Udaipur, Rajasthan (India). Many patients with history of trauma with head injury, whose identity cannot be ascertained, are admitted in our hospital. The management of these unattended patients from pre-hospital till discharge, rehabilitation or death is full of difficulties especially when surgical intervention has to be done. From March 16, 2015, until March 30, 2016, 118 consecutive patients unattended patients admitted in our department with history of head injury were enrolled in the study. Out of 118 patients, 107 (91%) were male, most were in the age group of 30-39 years. In majority of patients, 115 (97%) principal cause of head injury was road traffic accident. Majority of the patients 49 (41%) had Glasgow coma scale >13 on admission. Twenty three patients 23 (20%) died in hospital, 71 (60%) patients had good recovery. During the course of treatment identity of 115 patients was established and 92 (78%) patients, who survived were discharged to home. Three (3%) patients were shifted to destitute home. All discharged patients were followed at 1 month and 6 month interval. 78 (82%) & 76 (80%) patients showed good recovery (GOS) at 1 month & 6 month respectively. One patient expired at home within one month of discharge and 6 patients lost to follow up at 6 months.

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A clinical study of incidence of malignancy in solitary thyroid nodule in a tertiary care hospital

International Surgery Journal ◽

10.18203/2349-2902.isj20185490 ◽

2018 ◽

Vol 6 (1) ◽

pp. 293

Author(s):

Palani V. ◽

Reshma S.

Keyword(s):

Thyroid Nodule ◽

Thyroid Nodules ◽

Tertiary Care ◽

Care Hospital ◽

Solitary Nodule ◽

Medical College ◽

Solitary Thyroid Nodule ◽

The Mean ◽

A Prospective Study ◽

Optimum Management

Background: Thyroid nodules are common endocrine problem. A discrete swelling in an otherwise impalpable gland is termed as solitary nodule of thyroid. Solitary nodules have a high likelihood of being malignant. They should be characterized properly for optimum management. Aim of the study is to identify the incidence of malignancy in solitary nodule thyroid.Methods: A prospective study had been carried out from January 2018 to October 2018, in the Department of General surgery, ACS Medical College and Hospital, Chennai, India. Fifty patients, who presented with solitary thyroid swelling were examined clinically and confirmed after taking a detailed history and underwent thyroid surgery were included in this study. The histopathological reports were evaluated by standard statistical methods.Results: There were 50 cases of clinically detected solitary thyroid nodule with female preponderance more than males. The mean age of the incidence of solitary thyroid nodule is 35years. The incidence of malignancy in solitary thyroid nodule is 20%.Conclusions: It is concluded from the present study that 20% of solitary thyroid nodules are malignant, with female preponderance and a mean age of solitary thyroid nodule is 35years.

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Study of bacteriological profile and sensitivity to various drugs in a case of wound dehiscence in tertiary care centre

International Surgery Journal ◽

10.18203/2349-2902.isj20190569 ◽

2019 ◽

Vol 6 (3) ◽

pp. 724

Author(s):

Shashank Shekhar Tripathi ◽

Ankur Tripathi ◽

Rahul Singh ◽

Himansha Pandey

Keyword(s):

Surgical Procedures ◽

Surgical Complication ◽

Tertiary Care ◽

Wound Dehiscence ◽

Tertiary Care Centre ◽

Medical College ◽

Elective Surgical Procedures ◽

One Year ◽

A Prospective Study ◽

Prolonged Hospital

Background: Surgical wound infection is a common post-operative complication causing significant post-operative morbidity and mortality, prolonged hospital stays and adds between 10-20% to hospital cost.Methods: This is a prospective study conducted in Department of General Surgery and Department of Microbiology, M.L.N. Medical College and Swaroop Rani Nehru Hospital, Allahabad. The study group comprised of all patients who underwent surgery during the period from October 2017 to September 2018 and were diagnosed with postoperative surgical site infection and wound dehiscence.Results: A total of 1640 patients were followed during one year of study. 540 (32.92%) patients were operated as emergency cases while 1100 (67.08%) were operated as elective cases.Conclusions: Wound dehiscence is a common surgical complication occurring in about 6.5% of surgical procedures. Emergency operative procedures are associated with higher incidence (16.67%) of wound dehiscence as compared to elective surgical procedures (1.67%). Male gender is more commonly associated with wound dehiscence especially in case of emergency surgical procedures with male to female ration of 1.67:1.Incidence of wound dehiscence increases with increasing age being maximum in older age group. Malnutrition is the most common risk factor present in surgical patients predisposing to wound dehiscence.

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A STUDY OF URINARY TRACT ABNORMALITIES IN HOSPITALISED CHILDREN PRESENTING WITH URINARY TRACT INFECTION IN MIDNAPORE MEDICAL COLLEGE AND HOSPITAL

10.36106/ijsr/4125517 ◽

2021 ◽

pp. 71-73

Author(s):

Nabanita Das ◽

Mitali Bera ◽

Shabarna Roy ◽

Dhruba Kumar Mahata

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pediatric Patients ◽

Tertiary Care ◽

Tertiary Care Centre ◽

Medical College ◽

Number Of Children ◽

The Mean ◽

Tract Infections

Introduction: Urinary tract infection is the most common bacterial infection in childhood and upto 30% of infants and children experience recurrent infections during the rst 6 to 12 months after initial UTI. Urinary tract infections (UTI) imply invasion of urinary tract by pathogens, which may involve the upper or lower urinary tract depending on the infection in the kidney or bladder and urethra. Aims And Objectives: Children presenting with UTI by Ultrasonography, MCU and / or DMSA depending on the child's age. structural abnormalities and the presence of VUR if any in children with UTI by USG, MCU and DMSAscan in indicated cases. Materials And Methods: The study was conducted in the Pediatrics ward of Midnapore Medical College and Hospital. This is a tertiary care centre. Pediatric patients from different districts of West Bengal are referred to our Institute. All pediatric patients from 3 months to 12 years of age patients with a diagnosis of, either rst episode or recurrent UTI admitted at Midnapore Medical College and Hospital. Our study was an Observational, Prospective study. All the pediatric patients fullling the inclusion criteria, admitted to the hospital during the study period was enrolled for the study. Result And Analysis: We found in abnormal DMSA, the mean age (mean±s.d.) of children was 21.9375 ± 29.1398 years. In normal DMSA, the mean age (mean±s.d.) of children was 24.7321 ± 18.3179. In not required DMSA, the mean age (mean±s.d.) of children was 97.1667 ± 21.9855. Distribution of mean age in years vs. DMSAwas statistically signicant (p<0.0001). In abnormal DMSA, Conclusion: Even a normal USG report does not rule out dysfunctional bladder as we have had 3 children aged 19 months, 6 months and 26 months who had normal USG ndings but clear evidence of VUR on MCU of grades 2 ,4 and 1 respectively. In conclusion, abnormal US may carry a higher probability of grades III-VVUR and RS, and can affect the management in a signicant number of children hospitalized with UTI.

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