scholarly journals Esophageal inlet patch: Endoscopic prevalence in full sedated patients and Clinical significance.

2021 ◽  
Author(s):  
Remzi BESTAS ◽  
Nazım Ekin
Keyword(s):  
Clinical Significance ◽  
Clinical Features ◽  
Medical Records ◽  
Statistical Difference ◽  
Careful Examination ◽  
Common Symptom ◽  
Persistent Symptoms ◽  
Proximal Esophagus ◽  
Inlet Patch ◽  
The Mean

AİM: To determine the frequency, demographic and clinical features of the heterotopic gastric mucosa (inlet patch). MATERIALS AND METHODS: This retrospective study involves 244 patients who applied to the gastroenterology outpatient clinic with different symptoms between September 2016 and December 2019, and who were diagnosed with inlet patch in elective esophagogastroduodenoscopy. All endoscopic procedures were performed by the same clinical endoscopist. All medical records of patients including demographic and clinical features and endoscopy findings were reviewed. RESULTS: Considering 2823 patients who underwent elective esophagogastroduodenoscopy in the same study period, inlet patch was detected in 224 (8.6%). 56.6% of the patients diagnosed with inlet patch were male and there was no statistical difference between the two genders. The mean age of the patients was 37.73 ± 13.01 years. 83.6% of the patients had only one lesion, and 58.2% had a lesion larger than 1 cm, with the largest one being 4.5 cm. Size of the smallest lesion was 0.3 cm. All of the lesions were in the proximal esophagus. 54 patients (22.1%) had at least one supraesophageal or upper esophageal symptom. The most common symptom was globus sensation (64.8%). Patients with large lesions were more likely to experience symptoms (28.2% vs. 13.7%, p=0.008). CONCLUSION: Careful examination of the proximal esophagus may increase the chance of detecting inlet patch and may explain persistent symptoms in patients without a specific cause. Further understanding of the clinical significance of the disease may also prevent unnecessary diagnostic interventions.

scholarly journals Clinical Features of Imported Chinese COVID-19 Patients Following Chinese Inactivated Vaccines Injection Abroad

2021 ◽  
Author(s):  
Jianwu Li ◽  
Na Jiang ◽  
Qing-Lei Zeng ◽  
Yue Zhang ◽  
Yao Chu ◽  
...  
Keyword(s):  
Electronic Medical Records ◽  
Clinical Features ◽  
Medical Records ◽  
Severe Case ◽  
Shaanxi Province ◽  
Time Interval ◽  
Common Symptom ◽  
Limited Data ◽  
Inactivated Vaccines ◽  
The Mean

Abstract Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination has been demonstrated as an effective way to reduce the risk of coronavirus disease 2019 (COVID-19), and only a few vaccinees suffered from SARS-CoV-2 infection. However, limited data concerning the clinical features of these vaccinees infected with SARS-CoV-2 can be identified. Methods We retrospectively collected and analyzed epidemiological and clinical characteristics data of the imported COVID-19 cases who received Chinese inactivated vaccines abroad. Data were extracted from electronic medical records from a designated hospital in the Shaanxi Province of China between March 22 and May 17, 2021. Results Totally, 46 confirmed SARS-CoV-2 infection patients were enrolled. The mean age was 40.5 years (range 20-61), 41 (89.1%) are male. Eighteen (39.1%) patients were from Pakistan. Fourteen (30.4%) patients had at least one comorbidity. Forty (87.0%) and 6 cases were fully vaccinated and partly vaccinated. The time interval between vaccination and infection was 88 days (IQR, 33-123), 31 (67.4%) and 15 (32.6%) were asymptomatic and symptomatic cases, respectively. Fever (3/46, 6.5%) was the most common symptom; however, none had a body temperature higher than 38.0℃, and no severe case was observed. Notably, the rate of SARS-CoV-2 shedding discontinuation at 7 days after hospitalization in asymptomatic cases was higher than symptomatic one (93.5% vs 40%, P < 0.0001). Conclusions Individuals who received Chinese inactivated vaccines abroad remain have the probability to be infected with SARS-CoV-2, but all the vaccinees infected with SARS-CoV-2 were asymptomatic or had mild symptoms with favorable clinical outcomes.

scholarly journals Bone and joint tuberculosis in patients undergoing dialysis: clinical features, risk factors, and outcomes in 17 patients

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052094550
Author(s):  
Xuehua Wu ◽  
Jing Liu ◽  
Guorong Wang ◽  
Fengfeng Wu
Keyword(s):  
Risk Factors ◽  
Cell Count ◽  
Clinical Features ◽  
Medical Records ◽  
Delayed Diagnosis ◽  
Cd4 Cell Count ◽  
Spine Tuberculosis ◽  
The Mean ◽  
Anti Tubercular Therapy ◽  
Cd4 Cell

Objective This study was performed to investigate the clinical features, risk factors, and outcomes of bone and joint tuberculosis in patients undergoing dialysis. Methods We systematically reviewed the medical records of 17 patients with bone and joint tuberculosis undergoing dialysis who were admitted to our hospital from January 2009 to January 2019. Results Seventeen patients with bone and joint tuberculosis undergoing dialysis were identified in this retrospective study, and 13 patients were undergoing hemodialysis. The mean age of the 17 patients was 61.3 years (range, 32–82 years), and 10 (58.9%) patients were male. Most of the patients had a low CD4+ cell count and low hemoglobin and albumin levels. Surgery was performed in 6 patients (35.3%), and 13 of the 17 patients (76.4%) were cured. Three patients had bone or spine sequelae, mainly because of a delayed diagnosis, and one patient died of heart failure. Conclusion These findings indicate that older age, a low CD4+ cell count, and low hemoglobin and albumin levels are possible risk factors for bone and spine tuberculosis in patients undergoing dialysis. If diagnosed early, most patients should have a good outcome after anti-tubercular therapy with or without surgery.

scholarly journals Burden of herpes zoster among Brazilian adults – a hospital-based study

2021 ◽  
Vol 15 ◽  
Author(s):  
Ariane de Jesus Lopes de Abreu ◽  
Amanda Venys ◽  
Wilson Jacob ◽  
Thiago da Silva ◽  
Angela Henrique ◽  
...  
Keyword(s):  
Herpes Zoster ◽  
Clinical Features ◽  
Medical Records ◽  
Immunosuppressive Agents ◽  
Tertiary Care ◽  
Tertiary Hospital ◽  
Hospital Length Of Stay ◽  
First Episode ◽  
Care Hospital ◽  
The Mean

OBJECTIVE: To describe the clinical features of herpes zoster in adult patients treated at a large tertiary care hospital in Brazil over a 5-year period. METHODS: The medical records of suspected herpes zoster cases (based on ICD-10 codes) were identified for full review. Convenience sampling was used to select the medical records from a tertiary hospital in São Paulo. We collected data about co-existing medical conditions, medication use, herpes zoster-related clinical features and outcomes, and healthcare resource utilization. RESULTS: A total of 249 individuals whose first episode of herpes zoster occurred between 2010 and 2014 were included. The mean patient age was 55 years (range 18–96), and the majority were women (63.05%) and aged ≥ 50 years (63.86%). Medical comorbidities were reported in 92.77%, including diabetes (19.68%) and HIV infection (7.63%). Current/recent use of immunosuppressive agents was reported in 31.73%. A total of 65.86% of the patients were hospitalized: 102 patients (40.96%) were admitted for herpes zoster management, while 62 (24.90%) were already receiving inpatient care. The mean hospital length of stay was 16.60 days. One-third (34.14%) were managed as outpatients. Postherpetic neuralgia was reported as a complication in 18.07%. CONCLUSIONS: This retrospective descriptive study found a high frequency of herpes zoster episodes in older adults with comorbidities who sought medical care at a tertiary hospital. These results also underscore the importance of understanding the epidemiology of this disease and developing control strategies for these at-risk populations in Brazil.

scholarly journals Clinical Features of the Fellow Eyes of Children with Unilateral Facial Port-Wine Stains and Ipsilateral Glaucoma

2021 ◽  
Vol 62 (12) ◽  
pp. 1637-1642
Author(s):  
Young In Shin ◽  
Young Kook Kim ◽  
Sooyeon Choe ◽  
Yun Jeong Lee ◽  
Mirinae Jang ◽  
...  
Keyword(s):  
Clinical Features ◽  
Medical Records ◽  
Control Group ◽  
Port Wine ◽  
Initial Examination ◽  
Glaucoma Diagnosis ◽  
Significant Difference ◽  
The Mean ◽  
Fellow Eyes ◽  
Cup To Disc Ratio

Purpose: To investigate the clinical features of non-affected fellow eyes in patients with unilateral facial port-wine stain (PWS) and ipsilateral secondary glaucoma.Methods: We performed a retrospective analysis of the medical records of 35 patients with unilateral facial PWS glaucoma and those of controls (35 subjects without both facial PWS and glaucoma) between September 1996 and May 2020. We noted patients’ age at the glaucoma diagnosis (for unilateral facial PWS glaucoma patients) or at the initial examination (for controls), cup-to-disc ratio (CDR), and intraocular pressure (IOP). We compared the clinical features between the glaucoma-free eyes in patients with unilateral facial PWS glaucoma and the controls.Results: The mean age at the glaucoma diagnosis for unilateral facial PWS glaucoma patients was 0.56 ± 0.99 years (range, 0.08-4). The mean IOP of the glaucoma-free eyes was 16.68 ± 5.73 mmHg (range, 9-22.9), and the mean CDR was 0.37 ± 0.14 (range, 0.15-0.80) at glaucoma diagnosis. The mean IOP of the glaucoma-free eyes was 14.14 ± 6.29 mmHg (range, 8.1-26.7), and the mean CDR was 0.37 ± 0.12 (range, 0.26-0.82) at final examination. When comparing glaucoma-free eyes of the unilateral facial PWS glaucoma patients with the control group (mean age, 11.2 ± 7.4 years), the mean CDR was significantly greater (0.37 ± 0.12 vs. 0.30 ± 0.08; p = 0.014) but there was no significant difference in the mean IOP (14.14 ± 6.29 mmHg vs. 14.57 ± 2.49 mmHg; p = 0.712).Conclusions: The glaucoma-free eyes of unilateral facial PWS glaucoma patients showed greater CDR compared to the non-facial PWS and non-glaucoma controls. Additional longitudinal studies are needed to investigate the clinical course of those eyes, whether the risk of developing glaucoma is increased.

scholarly journals The clinical features and outcomes of Tolosa-Hunt syndrome

2021 ◽  
Author(s):  
Shin Yeop Oh
Keyword(s):  
Optic Nerve ◽  
Clinical Features ◽  
Medical Records ◽  
Facial Nerve Palsy ◽  
Ocular Motor ◽  
Hunt Syndrome ◽  
Study Results ◽  
History Of ◽  
The Mean

Abstract Background The objective of this study was to investigate the clinical features and outcomes of Tolosa-Hunt syndrome (THS). Methods A retrospective review of the medical records was performed on patients with THS between March 2016 and January 2020. A total of eleven patients fulfilling the ICHD-3 beta diagnostic criteria for THS were included in this study. Results The average age of the patients with THS was 57.18 ± 13.56 years and the mean duration of recovery was 26.91 ± 24.35 days. All nine patients had orbital or periorbital pain as the first symptom followed by diplopia. Ptosis was found in five patients (45.45%) in the involved eye. Sixth cranial nerve (CN) palsy was most common (eight cases, 72.73%), followed by third and fourth CN palsy (five cases, 45.45%, respectively), optic nerve (two cases, 18.18%), and trigeminal nerve and facial nerve palsy (one case, 9.09%, respectively). One patient with optic nerve (ON) involvement failed to recover visual acuity and the other ten patients completely recovered their ocular motor limitation. All patients were initially treated with steroids. One patient relapsed after five weeks and one patient had a history of THS five years earlier. Conclusions THS responded well to steroid treatment, but if it was accompanied by ON involvement, follow-up with active treatment was important.

Open Diverticulectomy and Cricopharyngotomy for Symptomatic Zenker's Diverticulum after Endoscopic Diverticuloesophagostomy

2019 ◽  
Vol 85 (3) ◽  
pp. 284-287
Author(s):  
Takuya Ogami ◽  
Joel Richter ◽  
John Jacobs ◽  
Vic Velanovich
Keyword(s):  
Surgical Resection ◽  
Medical Records ◽  
Operative Time ◽  
Symptomatic Improvement ◽  
Zenker’S Diverticulum ◽  
Open Resection ◽  
Short Term ◽  
Zenker's Diverticulum ◽  
Persistent Symptoms ◽  
The Mean

Two of the accepted treatments for symptomatic Zenker's diverticula are open resection of the diverticulum with cricopharyngotomy and transoral, endoscopic diverticuloesophagostomy with cricopharyngotomy. We report our experience with open surgical resection of the diverticulum with repeat cricopharyngotomy in patients with persistent symptoms after endoscopic diverticuloesophagostomy. This is a retrospective review of patients who underwent open surgical resection of the diverticulum, with repeat cricopharyngotomy in patients with persistent symptoms after endoscopic diverticuloesophagostomy. Medical records were reviewed for demographics, surgical detail, short-term complications, and symptomatic outcomes. Four patients underwent open resection of a Zenker's diverticulum with repeat cricopharyngotomy. There were two men and two women, with a mean age of 77.5 years. The mean operative time was 56 minutes and median length of stay was two days. All patients had improvement in dysphagia. Surgical diverticulectomy with cricopharyngotomy after failed endoscopic diverticuloesophagostomy is a technically challenging operation. However, symptomatic improvement can be achieved.

scholarly journals Effect of Ghrelin Hormone as a Diagnostic Factor on Appendicitis

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Ahmad Amouzeshi ◽  
Asghar Zarban ◽  
Seyede Narjes Yahooian ◽  
Bibi Fatemeh Shakhs Emampour
Keyword(s):  
Statistical Difference ◽  
Cross Sectional Study ◽  
Study Group ◽  
Common Symptom ◽  
Sectional Study ◽  
Cross Sectional ◽  
Statistical Population ◽  
The Mean ◽  
Serum Ghrelin ◽  
Larger Sample

Background. Appendicitis is the most common cause of surgery in people under 50. In America, it causes 250,000 cases per year and about 1 million days of hospitalization. Methods. This cross-sectional study was performed on 20 patients under appendectomy with diagnosis of acute appendicitis. The statistical population was divided into two groups, proven appendicitis in pathology and rejection of appendicitis in pathology. Then, 10 patients were assigned into each group. Results. A total of 20 patients were enrolled in this study, 9 of whom were female (45%) and 11 male (55%). The most common symptom was anorexia. However, there was no statistical difference between the two groups. The lowest level of serum ghrelin was 0.95 and the highest was 16.00 in the study group, which was the mean in people with appendicitis and nonappendicitis 6.24±4.09 and 5.12±4.85, respectively. These values were not significantly different between the two groups (T=0.45, df=18, p=0.65). Conclusion. This conclusion may be due to the small number of cases introduced into the study, which suggests that further investigation is warranted with a larger sample size.

scholarly journals The clinical profile of childhood optic neuritis

2001 ◽  
Vol 59 (2B) ◽  
pp. 311-317 ◽  
Author(s):  
Marco Aurélio Lana-Peixoto ◽  
Gustavo Cardoso de Andrade
Keyword(s):  
Multiple Sclerosis ◽  
Optic Neuritis ◽  
Clinical Features ◽  
Medical Records ◽  
Visual Loss ◽  
Visual Outcome ◽  
The Mean ◽  
Group 2 ◽  
Group 1

PURPOSE: To report the clinical features and outcome of a series of children with optic neuritis. METHODS: We reviewed the medical records of patients up to 16 years old with optic neuritis. Group 1 comprised children seen up to two weeks after the onset of visual loss; Group 2 comprised patients already harboring optic atrophy. RESULTS: There were 15 boys and 12 girls. The mean age was 10.9 years. Bilateral optic neuritis occurred in 10. Optic disc pallor was found in 35%, edema in 46%, and 19% had normal fundus. During follow-up visual acuity improved in all but one eye in Group 1, and in six of seven eyes in children in Group 2. Just one child converted to multiple sclerosis. CONCLUSIONS: This study shows that the clinical features of childhood optic neuritis differ from those observed in adults. In children it has a better visual outcome and a lower conversion rate to multiple sclerosis than in adults.

Evaluation of Low-Dose Gentamicin Once Daily Dosing Regimen at A General Hospital in Malaysia

2018 ◽  
Vol 9 (01) ◽  
Author(s):  
Ab Rahman A F ◽  
Md Sahak N. ◽  
Ali A. M.
Keyword(s):  
Medical Records ◽  
Public Hospital ◽  
Low Dose ◽  
Dosing Regimen ◽  
Once Daily ◽  
Neutropenic Sepsis ◽  
Wide Acceptance ◽  
The Mean ◽  
Initiation Of Therapy ◽  
Almost All

Objective: Once daily dosing (ODD) aminoglycoside is gaining wide acceptance as an alternative way of dosing. In our setting it is the regimen of choice whenever gentamicin is indicated. The objective of this study was to evaluate the practice of gentamicin ODD in a public hospital in Malaysia. Methods: We conducted a retrospective review of medical records of patients on gentamicin ODD who were admitted to Hospital Melaka during January 2002 until March 2010. All adult patients who were on ODD gentamicin with various level of renal function were included in the study. Patients on gentamicin less than 72 hours and pregnant women were excluded. Results: From 110 patients, 75 (68.2%) were male and 35 (31.8%) were female. Indications for ODD gentamicin included pneumonia, 34 (31.0%) neutropenic sepsis, 27 (24.5%) and sepsis, 11 (10.0%). The mean dose and duration of gentamicin was 3.2 mg/kg/day and 7 days, respectively. Almost all patients were on gentamicin combined with other antibiotics. Clinical cure based on fever resolution was found in 89.1% of patients treated with ODD. Resolution of fever took an average of 48 hours after initiation of therapy. The evaluation for bacteriologic cure could not be performed because of insufficient data on culture and sensitivity. Out of 38 patients with analyzable serum creatinine data, four patients might have developed nephrotoxicity. Conclusion: In our setting, lower dosages of ODD gentamicin when used in combination with other antibiotics seemed to be effective and safe in treating most gram negative infections.

Determination some Immunological Aspects in Pulmonary Tuberculosis Patients in Qadisiyah Province

2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Syoof Khowman Alramahy ◽  
Akram Hadi Hamza
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Statistical Difference ◽  
Positive Culture ◽  
Control Group ◽  
Tuberculosis Patients ◽  
Significant Difference ◽  
Lowenstein Jensen ◽  
The Mean ◽  
Igg Level

This study was carried out to study of some immunological aspects among the pulmonary Tuberculosis patients infected with causative agent, Mycobacterium tuberculosis. A Total of 200 sputum samples were collected from patients attending the consultant Clinic for Chest and Respiratory disease center, Diwaniya. Control group (No=15) also included. According to acid fast stain of sputum, the patients were classified as positive (No=91,45.5%) and negative (No=109,54.5, Lowenstein Jensen medium used for the cultivation of samples, on which 70% of sputum samples where positive culture for this microorganism. The grown microorganism were identified as M. tuberculosis, based on positive A.F.B, Niacin producers ,negative for catlase at 68c. The mean IgG level was l184.053±76.684 mg/100 ml in tuberculosis group compared with 1016.533 ± 44.882 mg/100ml in control group, rendering the statistical difference significant. For IgA and IgM levels, they were at mean of 315.880±38.552 mg/100 ml and 119.527±8.464 mg/100 ml in control group compared with 396.358±38.776 mg/100 ml and 134.207±11.696 mg/100 ml in patients group respectively with significant difference

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