scholarly journals Genotype, sex and interaction effect on lamb growth traits

2015 ◽  
Vol 31 (1) ◽  
pp. 37-44 ◽  
Author(s):  
V.C. Petrovic ◽  
M.P. Petrovic ◽  
D. Ruzic-Muslic ◽  
N. Maksimovic ◽  
M Selionova ◽  
...  

The pure breeds and crossing have an important role in production. It is essential in sheep meat production to maintain the genetic diversity of the adapted breeds, pure breeds and their crosses. Objective of the study is to determine the impact of genotype and sex on growth traits of lambs. Results of the study showed that male of all genotypes were dominant on body weight in all ages (from BWB to BW90). The highest birth weight (BWB) got male of genotype 2 (W). The lowest body weight at birth was the female lambs of genotype 1 (P). Body weights at ages 30, 60 and 90 days, male and female of genotype 4 (PxWxF) were dominant among other genotypes. Genotype 1 (P) of both sexes had the lowest bodyweights in all ages (BWB, BW30, BW60, BW90). The result showed better growth efficiency from males compared with females. The results of fixed factors and its impact on body weights of lambs showed very significant effect of genotype (P<0.01) on body weights of lambs at birth (BWB), ages 30, 60 and 90 days (BW30, BW60, BW90). The effect of sex had highly significant effects (P<0.001) on all ages. The interaction between genotype x sex showed a very significant effect (P?0.01) on body weight at birth (BWB) but were not significant (P?0.05) on body weights of lambs at ages BW30, BW60 and BW90. Superiority on growth traits of genotype 4 (PxWxF) at ages 30, 60 and 90 days, indicating that three-bred crossing resulted in high growth traits.

2017 ◽  
Vol 25 (4) ◽  
pp. 329 ◽  
Author(s):  
M. Sakthivel ◽  
D. Balasubramanyam ◽  
P. Kumarasamy ◽  
H. Gopi ◽  
A. Raja ◽  
...  

The genetic parameters of growth traits in the New Zealand White rabbits kept at Sheep Breeding and Research Station, Sandynallah, The Nilgiris, India were estimated by partitioning the variance and covariance components. The (co)variance components of body weights at weaning (W42), post-weaning (W70) and marketing (W135) age and growth efficiency traits viz., average daily gain (ADG), relative growth rate (RGR) and Kleiber ratio (KR) estimated on a daily basis at different age intervals (42 to 70 d; 70 to 135 d and 42 to 135 d) from weaning to marketing were estimated by restricted maximum likelihood, fitting 6 animal models with various combinations of direct and maternal effects. Data were collected over a period of 15 yr (1998 to 2012). A log-likelihood ratio test was used to select the most appropriate univariate model for each trait, which was subsequently used in bivariate analysis. Heritability estimates for W42, W70 and W135 were 0.42±0.07, 0.40±0.08 and 0.27±0.07, respectively. Heritability estimates of growth efficiency traits were moderate to high (0.18 to 0.42). Of the total phenotypic variation, maternal genetic effect contributed 14 to 32% for early body weight traits (W42 and W70) and ADG1. The contribution of maternal permanent environmental effect varied from 6 to 18% for W42 and for all the growth efficiency traits except for KR2. Maternal permanent environmental effect on most of the growth efficiency traits was a carryover effect of maternal care during weaning. Direct maternal genetic correlations, for the traits in which maternal genetic effect was significant, were moderate to high in magnitude and negative in direction. Maternal effect declined as the age of the animal increased. The estimates of total heritability and maternal across year repeatability for growth traits were moderate and an optimum rate of genetic progress seems possible in the herd by mass selection. The genetic and phenotypic correlations among body weights and between growth efficiency traits were also estimated. Moderate to high heritability and higher genetic correlation in body weight traits promise good scope for genetic improvement provided measures are taken to keep the inbreeding at the lowest level.


2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 789-789
Author(s):  
Marcia Monaco ◽  
Victoria Daniels ◽  
Mei Wang ◽  
Johanna Hirvonen ◽  
Henrik Max Jensen ◽  
...  

Abstract Objectives Human milk contains both prebiotic oligosaccharides and live bacteria, which are thought to bring health benefits to breastfed infants. Herein, we investigated the impact of formula supplementation with 2'-fucosyllactose (2'FL) and Bifidobacterium longum subsp. infantis (Bi-26) alone or in combination on growth, organ weights, and intestinal development of neonatal piglets. Methods Two-day-old intact male piglets (N = 53) were randomized to be fed a nutritionally-adequate milk replacer ad libitum without (CON) or with 1.0 g/L 2'FL (FL). Pigs were further stratified to receive either 12% glycerol solution alone or Bi-26 (109 CFU) in glycerol orally once daily (BI and FLBI). Body weights and food intake were monitored from postnatal day (PND) 2 to 33/34. On PND 34/35, animals were euthanized, intestine, liver and brain weights were assessed, and intestinal samples were collected for morphological analyses and disaccharidase activity. Dry matter of intestinal contents was also measured. Growth and food intake were analyzed as a 3-way, repeated-measures ANOVA with fixed effects of prebiotic, probiotic, and day, whereas all other variables were analyzed by a 2-way ANOVA with fixed effects of prebiotic and probiotic. Level of significance was set at P ≤ 0.05 and trends are reported at 0.05 &gt; P &lt; 0.1. Results All diets were well tolerated and food intake did not differ among the treatment groups. Daily body weights were affected by 2’FL, Bi26, and day, but no interaction was observed. However, there was a trend (p = 0.075) for greater body weight gain in CON vs. all other groups. No differences were observed for intestine, liver, or brain weight per kg body weight, jejunal or ileal lactase or sucrase activities, or fecal dry matter among the groups. Histomorphological outcomes in jejunum, ileum, and ascending colon were similar in all groups, except for a trend (p = 0.069) for larger ileal crypt volume in FL vs. CON piglets. Conclusions The addition of 2'FL and/or Bi-26 to milk replacer supported piglet growth with no detrimental effects on body and organ weights, or intestinal structure and function. Funding Sources DuPont Nutrition & Biosciences.


Author(s):  
C. Radovic ◽  
M. Petrovic ◽  
N. Parunovic ◽  
D. Radojkovic ◽  
R. Savic ◽  
...  

Objective of this paper was to evaluate phenotypic variability of carcass side and pork quality traits of fatteners (male castrated and female heads). Investigation included 12 pigs per group of Mangalitsa (Genotype 1), Moravka (Genotype 2), cross-breed Mangalitsa with Moravka (Genotype 3) and cross-breed Moravka with Duroc boar (Genotype 4). Results show that Mangalitsa had lower daily gain (268 g) than other genotypes (p<0.001). The greatest difference for fat thickness was determined between Genotype 1 and Genotype 4. As expected, the thinnest fat and maximum value for gain and depth of Musculus longissimus (ML) had the Genotype 4. The highest value for the ML surface was found in Genotype 4(47.52 cm2) whereas for the same trait in Mangalitsa the lowest value was observed (24.16 cm2). Mangalitsa had significantly lower L*, a* and b* values of ML compared with all other groups (p<0.001). Considering the low production performance of indigenous pig breeds, crossbreeding with the Duroc breed will contribute a improvement of growth and carcass traits.


2012 ◽  
Vol 28 (4) ◽  
pp. 743-749
Author(s):  
V. Caro-Petrovic ◽  
M.P. Petrovic ◽  
M.M. Petrovic ◽  
Z. Ilic ◽  
N. Maksimovic ◽  
...  

Some phenotypic and genetic trends on growth traits of lambs are observed. The research implicated lambs of two local breeds of sheep: Lipska (LP) and Svrljig (SV). All lambs were weighed for the first time at birth (BWB), and thereafter, regularly in two-week intervals. On the basis of the results during weighing the body weight (BW) were adjusted to the average age: 30 (BW30), 60 (BW60) and 90 days (BW90). Results of the effect of genotype on growth showed a significant effect on the growth traits. Sex of lambs had a significant effect at birth and very significant effect at 30 days, but had no significant effect on weight at 60 (BW60) and 90 (BW90) days. Birth type had significant effect on the body weight from birth to weaning and the highest body weights were recorded in singles. Phenotypic correlations were positive and very highly significant between the growth traits. Genetic correlations were significant, but not between all observed ages of lambs.


2018 ◽  
Vol 3 (4) ◽  
pp. 499-503
Author(s):  
Md Shahjahan ◽  
Asma Khatun ◽  
Sumya Khatun ◽  
Md Mahbubul Hoque ◽  
Sohrab Hossain ◽  
...  

This study was planned to clarify the variation of body weight and average daily gain traits in both indigenous and F1 crossbreed (Local×Mediterranean) buffalo at weaning (sixth month) and yearling stages (twelfth month). Data were collected from 33 indigenous and 35 F1 crossbred buffalo progeny during the period of 2011 to 2014 with intensive management system at Research and Development farm of Lal Teer Livestock Limited in Bangladesh. The gathered data were analyzed using general linear model (GLM) and independent sample t test. The effect of parity, sex, season and breeding year on body weight and average daily gain were observed where significant values found in breeding period (p <0.01) of crossbred buffalo for body weight. It might be the reason of crossbreeding to indigenous buffalo cows using imported semen with better genetic merit. The parity (p <0.05), season (p <0.05) and breeding period (p <0.01) were also significant for average daily gain measurement which suggesting environmental adaptability beside additive genetic effects. Body weights were measured at weaning and yearling stages for both local (113 to 195 kg) and F1 crossbred (144 to 220 kg) buffalo progeny to screen the elite offspring for the Genetic Farm and Bull station. Similarly, average daily gain observed 469 to 457 g and 600 to 506 g at the previously mentioned two stages for both local and F1 buffalos, respectively. It was observed that studied traits were comparatively better in F1 buffalo progeny than indigenous. The comparison of average daily weight gains between indigenous and F1 buffalos at weaning and yearling periods showed significant differences for body weight (p <0.001) and average daily gain (p <0.05), respectively. It is concluded that genetic gain might be possible in local buffalo population by grading up process which could switch the traditional buffalo rearing to commercial level as well as meeting the nutritional demand of country people.Asian J. Med. Biol. Res. December 2017, 3(4): 499-503


2020 ◽  
Vol 49 (1) ◽  
pp. 13-21
Author(s):  
M Solaiman ◽  
AS Apu ◽  
MY Ali ◽  
M Fakruzzaman ◽  
MO Faruque

The present study was undertaken to evaluate the availability of breeding bucks as well as growth and reproductive performances of Black Bengal goat under community based breeding program. A total of 30 goat rearers in three areas of Sakhipur upazilla were selected based on the survey result. Selected goat rearers were trained on scientific rearing, management and community-based breeding of Black Bengal goat and also build up community link with them. Three Black Bengal breeding bucks have been distributed among three potential farmers in three villages under Sakhipur upazilla. The management and performance of Black Bengal goats were monitored closely and analyze the impact of community based breeding program. The analysis of the growth performance showed that male kids attained significantly (p<0.05) higher birth weight (1.28±0.04 kg) than that of female kids (1.06±0.02 kg). The body weights of male at 3, 6, 9 and 12-month were 5.41±0.28, 9.18±0.32, 12.87±0.35 and 16.91±0.46 kg whereas female reached significantly (p<0.05) lower body weight as 4.97±0.16, 8.02±0.21, 10.91±0.23 and 14.21±0.34 kg at the same ages, respectively. Average daily body weight gain up to 12 months of age was also significantly (p<0.05) higher in males (43.42±1.17 g/day) than females (36.53±2.49 g/day). On the other hand, season had a significant effect (p<0.05) on the body weights of Black Bengal goat at 0 (birth), 3, 6, 9, 12-month of age. In case of reproductive performances, it was revealed that age at sexual maturity was 199.32±2.41 days; age at first kidding 393.23±1.38 days; service per conception 1.17±0.04, and litter size was 1.76±0.08 in community based breeding program. Beside these, post-partum heat period of Black Bengal goat was found 47.50±0.87 days. Comparing with the findings of previous research works, these results suggested that community based breeding program has not only reduced the scarcity of good quality breeding bucks but also improved the growth and reproductive performances of Black Bengal goats. Bang. J. Anim. Sci. 2020. 49 (1): 13-21


1978 ◽  
Vol 26 (2) ◽  
pp. 185-192 ◽  
Author(s):  
A. Farid ◽  
M. Makarechian

ABSTRACTThe pre-weaning records (birth weight, weaning weight and gain from birth to weaning) of 291 male and female lambs and the post-weaning records (body weight, feedlot gain and food conversion) of 136 male lambs were used to study relationships between different traits. The lambs were derived from three fat-tailed Iranian sheep breeds (Karakul, Mehraban and Naeini) and their crosses with Corriedale and Targhee rams. All lambs were weaned at 75 + 5 days of age and the males were fed in a feedlot for 100 days after weaning. Feedlot measurements were taken at 20-day intervals.Weaning weight and pre-weaning average daily gain showed positive and significant associations with birth weight. Birth weight, weaning weight and gain from birth to weaning were positively associated with body weight at subsequent ages in feedlot as well as with final weight (P<0·01). Birth weight, weaning weight and pre-weaning average daily gain were positively and significantly associated with total feedlot gain.Of the different traits, total gain during the first 20 days in feedlot (adjust period) had the lowest and total gain during the second 20 days had the highest association with total feedlot daily gain. There was no evidence that the heavier lambs at weaning and those showing high growth rate before weaning, were more efficient in the feedlot. Gain during the second 20-day period in the feedlot had a significant negative association with the total food conversion (unit food/unit gain) and therefore was a good predictor for food conversion.When the feedlot period was divided into two 40-day periods, it was found that gain during both had a significant negative association with the corresponding food conversion. A similar association was observed between total feedlot gain and food conversion, indicating that the rate and efficiency of gain improved simultaneously.


2015 ◽  
Vol 59 (12) ◽  
pp. 7426-7436 ◽  
Author(s):  
Sanne B. Jensen ◽  
Stéphanie B. N. Serre ◽  
Daryl G. Humes ◽  
Santseharay Ramirez ◽  
Yi-Ping Li ◽  
...  

ABSTRACTVarious protease inhibitors (PIs) currently are becoming available for treatment of hepatitis C virus (HCV). For genotype 1, substitutions at NS3 protease positions 155, 156, and 168 are the main determinants of PI resistance. For other genotypes, similar substitutions were selected during PI treatment but were not characterized systematically. To elucidate the impact of key PI resistance substitutions on genotypes 2 to 6, we engineered the substitutions R155A/E/G/H/K/Q/T, A156G/S/T/V, and D/Q168A/E/G/H/N/V into HCV recombinants expressing genotype 2 to 6 proteases. We evaluated viral fitness and sensitivity to nine PIs (telaprevir, boceprevir, simeprevir, asunaprevir, vaniprevir, faldaprevir, paritaprevir, deldeprevir, and grazoprevir) in Huh7.5 cells. We found that most variants showed decreased fitness compared to that of the original viruses. Overall, R155K, A156G/S, and D/Q168A/E/H/N/V variants showed the highest fitness; however, genotype 4 position 168 variants showed strong fitness impairment. Most variants tested were resistant to several PIs. Resistance levels varied significantly depending on the specific substitution, genotype, and PI. For telaprevir and boceprevir, specific 155 and 156, but not 168, variants proved resistant. For the remaining PIs, most genotype 2, 4, 5, and 6, but not genotype 3, variants showed various resistance levels. Overall, grazoprevir (MK-5172) had the highest efficacy against original viruses and variants. This is the first comprehensive study revealing the impact of described key PI resistance substitutions on fitness and PI resistance of HCV genotypes 2 to 6. In conclusion, the studied substitutions induced resistance to a panel of clinically relevant PIs, including the newer PIs paritaprevir, deldeprevir, and grazoprevir. We discovered complex patterns of resistance, with the impact of substitutions varying from increased sensitivity to high resistance.


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 234-235
Author(s):  
Emhimad Abdalla ◽  
Bayode Makanjuola ◽  
Benjamin Wood ◽  
Christine F Baes ◽  
Ryley J Vanderhout

Abstract The underlying genetic mechanisms affecting turkey growth traits have not been widely investigated. Over the last few years, genome-wide association studies (GWAS) became the de facto approach to identify candidate regions associated with complex phenotypes and diseases in livestock. In the present study, we performed GWAS to identify regions associated with growth traits, feed intake and walking ability in a breeding turkey line. This was followed by studying the functional evidence that may support the impact of those regions on the economic traits in turkeys. A total of 31,950 phenotypic records for body weight, feed intake and walking ability with genomic (56,393 SNP) data were provided by Hybrid Turkeys, Kitchener, Canada. The analysis was carried out using a mixed linear model with hatch-week-year and sex fitted as fixed effects and the accumulated effect of all markers captured by the genomic relationship matrix fitted as random polygenic effects. Significant markers were observed on several chromosomes across the turkey genome. For example, COL8A1 and RBPMS2 genes were identified on chromosome 1 and 12, respectively, and associated with body weight. Furthermore, a gene-set enrichment analysis was performed for each trait. These functional and positional analyses uncovered a number of gene ontology functional terms, Reactome pathways and Medical Subject Headings that showed significant enrichment of genes associated with the studied traits. Many of the observed gene ontology functional terms (e.g., skeletal muscle tissue growth, regulation of digestive system process, and adult walking behavior) are known to be related to body growth, feed intake and walking ability. The results of this study revealed novel candidate genomic regions and candidate genes that could be managed within a turkey breeding program.


Author(s):  
Mohamed Afifi ◽  
Tamer S. Abdelmoneim ◽  
Peter H. Brooks ◽  
Ayman Abdel-Aziz Swelum

This study aimed to evaluate the relationship between growth hormone (GH) gene polymorphism and estimated body weight in Harri sheep. One hundred Harri sheep lambs were used to determine the birth weight (BW) and weight at 120 days of age. The daily live-weight gain (DLWG) 0-120 days (g) was calculated. The complete CDS of the Harri sheep GH gene is 2117pb in length (GenBank acc. no. KU255857). Three novel SNPs were detected by comparing with GenBanke acc. no. X12546_1. The G871A SNP in intron II, G1383A in exon IV that resulted in conversion of the amino acid arginine number 121 to lysine (R121K) and the A1509G in intron IV. Each SNP was found on both alleles the mutant homozygote was more common (48, 56 and 50%) than the heterozygote (30, 18 and 20%) for G871A, G1383A and A1509G respectively.A positive significant (P is less than 0.05) correlation between growth traits (BW, 120 day body weight and DLWG) and SNP and a highly significant correlation with the genotype were detected. The regression analysis indicated the positive effect of genotype and SNPs on the growth traits. Individuals carrying homozygote mutant alleles had the heaviest body weight and the highest DLWG. Consequently, these SNP may be useful indicators in the selection of lambs for higher growth rate and meat production


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